Articles tagged with Type 2 Diabetes
A recent study found that diabetes prevalence increased globally between 1993 and 1999. However, mortality rates from diabetes decreased by 3% during this period. The researchers suggest that earlier treatment and improved healthcare may contribute to the decline in mortality rates.
A study by Joslin Diabetes Center has identified a family of metabolic genes associated with type 2 diabetes risk. The research found that 55 genes showed altered activity in both people with diabetes and those at high risk for prediabetes, suggesting a continuum from normal to diabetic states.
Researchers found that 30% of diabetic patients with kidney disease do not exhibit common symptoms like protein in urine and eye disease. The current approach of screening for these symptoms alone is insufficient, and a blood test measuring kidney function directly is recommended.
A study found that prenatal exposure to a diabetic environment from mothers with type 1 diabetes is associated with increased occurrence of impaired glucose tolerance and a defective insulin secretory response in adult offspring. This effect was observed independently of genetic predisposition to type 2 diabetes.
A study found that regular physical activity, especially brisk walking, significantly reduces the risk of cardiovascular disease and death in men with diabetes. Diabetic men who were in the third highest category of total physical activity reduced their risk by 36 percent.
A new study suggests that type 1 diabetics can develop insulin resistance, increasing their risk of heart disease. Insulin resistance occurs when the body fails to use insulin properly, leading to high blood sugar levels and a greater risk of cardiovascular events.
A University of Pittsburgh study examines the effects of gastric bypass surgery on type 2 diabetes in 1,150 patients over a five-year period. The results show that diabetes resolves after an average of 62 days following surgery, with patients experiencing significant weight loss and improvement in glucose levels.
A unique program, ENERGY, has been established to reduce childhood obesity and type 2 diabetes among elementary school students. The program incorporates science education enrichment activities to promote healthy eating and active living.
The American College of Physicians recommends aiming for blood pressure levels less than 135/80 mm Hg in patients with type 2 diabetes. Thiazide diuretics and ACE inhibitors can be used as first-line agents to control blood pressure, but patients may need multiple medications.
The ACCORD clinical trial enrolls 10,000 adults with type 2 diabetes to test the effects of intensively controlling blood sugar along with aggressive control of blood pressure and lipids. The study aims to address the significant public health challenge of cardiovascular disease in people with type 2 diabetes.
A new study aims to investigate the effects of intensively controlling blood sugar, blood pressure, and lipid levels on cardiovascular disease risk in adults with type 2 diabetes. The ACCORD study will test three medical treatment strategies to determine their impact on CVD risk.
A Pittsburgh study found that even among those with normal weight, excess fat distribution in the body increases insulin resistance and type 2 diabetes risk. The study of elderly men and women with normal glucose tolerance showed that two-thirds of those with type 2 diabetes were not obese.
A new study from the Liverpool Diabetic Eye Study has proposed optimal screening intervals for diabetic eye disease, based on incidence data. The findings suggest that patients with no baseline retinopathy should be screened every 3 years, while those with background retinopathy can be screened annually.
A large study of over 17,000 Dutch adults found that those who drank seven or more cups of coffee a day were 50% less likely to develop type-2 diabetes. The study suggests that components of coffee other than caffeine may be beneficial for glucose metabolism, but long-term effects are unknown.
Regular aerobic and weight-lifting activities can help diabetics control blood sugar and lower blood pressure, also providing cardiovascular benefits. Exercise training reduces total and abdominal fat, leading to improvements in insulin sensitivity, blood pressure, and blood vessel function.
The InnoLet system features a dosing dial and reversible dose mechanism, making it easier for patients to administer accurate doses. Clinical studies show that 95% of participants rated the device as 'very easy' or 'easy' to use.
The XENDOS study found that 28.3% of obese individuals had undetected or untreated diabetes or pre-diabetes. Xenical-treated patients experienced significant weight loss and improved cardiovascular risk factors compared to lifestyle intervention alone.
The XENDOS study demonstrates that Xenical plus lifestyle intervention is more effective than lifestyle intervention alone in preventing or delaying the development of type 2 diabetes. Significant and sustained weight loss was achieved with Xenical, which also improved cardiovascular risk factors.
A group-based stress management training program has been found to lower blood glucose levels and improve health outcomes in people with type 2 diabetes. After one year, 32% of participants showed a reduction in hemoglobin A1C levels, while only 12% of those receiving no stress management training did so.
Consuming whole grains daily can lower incidence of type 2 diabetes, particularly in non-obese men. High fiber and magnesium content in whole grains slows glucose release and improves insulin response, leading to reduced risk.
A study found that high whole-grain consumption was associated with lower rates of type 2 diabetes and cardiovascular disease. Participants who consumed more whole grains had healthier lifestyle habits, including a lower waist-to-hip ratio, less saturated fat, and more fruits and vegetables.
Recent studies have shown that combining Xenical with a mildly reduced calorie diet can improve glycaemic control, body weight, and waist circumference in overweight or obese patients with type 2 diabetes. The medication has been found to reduce HbA1c levels by as much as 46% in patients with poor glycaemic control.
Researchers found Xenical significantly improved HbA1c and fasting plasma glucose levels in patients with type 2 diabetes. Additionally, treatment with Xenical showed post-prandial glucose benefits and cost-effectiveness as an adjunctive therapy to oral anti-diabetic medications.
A one-year study found that a diet reducing fat and calories, combined with walking, led to an average weight loss of 8.5% and improved blood sugar levels. Exercise was reported as the most beneficial behavior among participants.
Researchers found that early treatment with insulin-resistant drugs saves about 30% more beta cells than late intervention, preventing type 2 diabetes. The study suggests that lessening the workload on beta cells can prevent or slow disease onset.
A new study examines the relationship between adiponectin levels, body composition, and obesity-related risk factors in children. The research suggests that children from lower socio-economic backgrounds are at high risk of developing type-2 diabetes due to dysregulation of adiponectin secretion.
Many obese children and adolescents have impaired glucose tolerance, a precursor to type 2 diabetes. Researchers found that 25% of obese kids under 10 and 21% of teens between 11-18 had impaired glucose tolerance.
A pilot study suggests that continuous administration of GLP-1 can improve insulin sensitivity, b-cell function, and reduce blood glucose levels in patients with type 2 diabetes. The treatment also resulted in weight loss and reduced appetite, with no reported side effects.
Scientists discovered that mice without the myostatin protein gain less fat as they age, even though they eat the same amount of food. This could lead to a new approach for treating type 2 diabetes by increasing muscle mass, which may improve insulin sensitivity.
A large study of men's health habits found that a prudent diet significantly reduces the risk of developing type 2 diabetes. The study indicates that avoiding weight gain and eating a balanced diet may substantially reduce this risk, highlighting the importance of a healthy lifestyle in preventing the disease.
The Look AHEAD trial will examine the effects of a lifestyle intervention program on cardiovascular health in people with type 2 diabetes. The study, which began screening participants in July, aims to enroll 5,000 volunteers and follow them for up to 11.5 years.
A survey of practice nurses found that 85% are underestimating the prevalence of insulin resistance in type 2 diabetes patients. This lack of awareness can lead to inadequate treatment and education, highlighting the need for increased understanding of insulin resistance as a fundamental cause of type 2 diabetes.
A survey found that nearly two-thirds of GPs are unaware that insulin resistance is present in 92% of people with type 2 diabetes. This lack of understanding can lead to suboptimal treatment, as insulin resistance improves glycaemic control and reduces cardiovascular complications.
A groundbreaking study has found that Avandia can prevent the development of Type 2 diabetes in patients with impaired glucose tolerance, a condition affecting millions worldwide. The results have provided proof of concept for a larger prospective study to establish the effectiveness of Avandia in preventing Type 2 diabetes.
Researchers have developed a mouse model that replicates the clinical features of type 2 diabetes, enabling studies on pathogenesis and testing of new therapies. The strain of mice, generated by selectively mutating an insulin-like receptor in muscle cells, fully recapitulates the disease's progression.
Virginia Tech researchers are exploring a plant-based approach to produce a human enzyme for treating Type 2 diabetes. The project aims to create a transgenic plant that can cheaply produce D-chiro inositol, which is currently synthesized through expensive and painful processes.
New studies announce that AVANDIA (rosiglitazone maleate) may significantly reduce insulin resistance and lower cardiovascular risk in Type 2 diabetes patients. Insulin resistance is a fundamental cause of the condition, and targeting it with AVANDIA could lead to better outcomes.
A USC study found that administering a drug to lower insulin resistance in women at high risk for type 2 diabetes successfully prevents or stalls its onset. The study tested whether reducing the demands on beta cells could prevent diabetes in Latinas with recent gestational diabetes.
Researchers found that combining a long-acting AT1-receptor blocker with an ACE inhibitor reduces blood pressure and albumin excretion in hypertensive type 2 diabetic patients. The study also showed that combined treatment is more effective than using either drug alone.
A study found no significant difference in reducing maternal weight gain and gestational diabetes among Cree women, suggesting cultural factors and intervention intensity as contributing factors. Culturally appropriate modifications to interventions are proposed to reduce the risk of diabetes in pregnancy among this population.
The DIRECT programme aims to establish whether candesartan cilexetil can prevent and treat diabetic retinopathy. The trial will investigate the effect of RAS blockade on diabetic patients with and without retinopathy.
Scientists have identified a major susceptibility gene for type 2 diabetes in Mexican Americans, also affecting two European populations. The discovery provides new approaches to prevention, diagnosis and treatment of the disease.
A new genetic variation in the calpain-10 gene has been identified as a significant contributor to type 2 diabetes. This discovery provides new insight into the origins of the disease and its impact on patients' lives, offering potential therapeutic approaches for treatment.
Researchers found that female mice lacking IRS-2 protein are infertile due to defective ovaries and abnormal hormone production. The study suggests an evolutionarily conserved pathway linking energy metabolism and fertility in humans and animals, with potential implications for diabetes treatment.
Avandia targets both fundamental causes of type 2 diabetes by reducing insulin resistance and improving beta-cell function, providing enhanced glycaemic control. This dual therapeutic approach may delay disease progression and alter outcomes.
Studies show Avandia reduces hepatic fat and increases subcutaneous fat without increasing intra-abdominal fat, a key factor in type 2 diabetes. The medication also decreases plasminogen activator inhibitor-1 levels, associated with cardiovascular risk factors.
Type 2 diabetes accounts for 90% of all cases, with rising costs placing a strain on healthcare resources. Insulin usage and complications are key drivers of increased costs.
The launch of Avandia provides patients with inadequate glycaemic control a new treatment option. Adding Avandia to metformin improves fasting plasma glucose levels in obese patients, reducing the risk of disease progression. This combination therapy also shows promise for patients with mild-to-moderate renal impairment.
A new diet study, funded by Duke University Medical Center, aims to test the hypothesis that reducing fat intake can halt or slow diabetes progression. Participants will consume specially prepared foods with Olestra instead of real fat, allowing researchers to study a low-fat diet independently from a low-calorie diet.
A recent study reveals that primary care practices neglect to counsel diabetic patients on how to self-manage their illness, leading to a lack of comprehensive disease management. Despite this, patients who utilized community resources for support received more medical and counseling-related services from their physicians.
Researchers found that Avandia had a lower rate of elevated alanine aminotransferase (ALT) levels compared to placebo and other treatments. This suggests that Avandia is a valuable option for patients with type 2 diabetes, as it can help improve blood sugar control and potentially slow disease progression.
Researchers found that Avandia improves beta cell function, as measured by proinsulin to insulin ratio, indicating potential benefits for long-term glycemic control and disease progression. The study's results support the use of Avandia in type 2 diabetes treatment and suggest its potential to delay disease progression.
The National Heart, Lung, and Blood Institute recommends a more aggressive approach to treating high blood pressure in patients with type 2 diabetes. This is based on studies showing significant reductions in diabetes-related strokes, small blood vessel damage, and deaths when blood pressure is brought under control.
Researchers link HIV-protease inhibitors to increased diabetes risk due to impaired glucose storage, prompting reevaluation of screening methods and development of new treatments. Up to 83% of patients on the drugs develop excess belly fat and type 2 diabetes.
A nine-year study found that African-American women are 2.4 times more likely to develop diabetes due to lifestyle factors such as poor diet and lack of exercise. The study suggests that adopting a healthier lifestyle can help reduce the risk of developing diabetes in this population.
According to a study published in JAMA, African American women and men are more likely to develop type 2 diabetes than their white counterparts. The researchers found that being overweight was a significant factor in the excess risk for African American women, while high blood pressure was a key contributor for African American men.
A prospective cohort study found that regular exercise can benefit men with type 2 diabetes, while low physical fitness is associated with mortality. Meanwhile, a dangerous combination of blood thinners and intravenous steroids requires daily monitoring to prevent life-threatening bleeding.
Researchers found that taking American ginseng before a meal reduced blood sugar levels in both diabetic and non-diabetic individuals. The study's findings suggest that controlling after-meal blood sugar levels may be an important strategy in managing diabetes and preventing its onset.
A study led by Johns Hopkins found that patients with high blood pressure taking beta blockers were 28% more likely to develop diabetes than those not taking the medication. In contrast, thiazide diuretics were associated with a lower risk of diabetes.
Researchers found that diabetics under specialist care had significantly lower blood glucose levels and higher participation in self-care practices. The effect was particularly notable among patients with lower education levels.