Articles tagged with Open Access
The EU project CRAFT-OA aims to strengthen institutional publishing using Diamond Open Access model across Europe. The project will enable local platforms and service providers to expand their content services with the aim of networking them with other information systems in science.
Researchers discovered PDGF cross-signaling through alternative receptors in colorectal cancer cells, enabling bypassed signaling. This finding supports anti-PDGF therapy as a combination strategy alongside VEGF and EGF targeting.
The UTEP-led Computing Alliance will receive $4.8M from Google to improve diversity in computer science fields. The project aims to attract, prepare and support Hispanic students for graduate degrees, with initiatives including lab design, financial support and research collaborations.
The Journal of the Pediatric Infectious Diseases Society has published a supplement issue focusing on past, current, and future diversity and inclusion issues affecting pediatric infectious diseases. The collection examines the legacy of health disparities and their impact on the response to COVID-19.
Researchers have successfully fabricated bifunctional flexible electrochromic supercapacitors using silver nanowire flexible transparent electrodes. The devices can exhibit color changes to display energy status, offering potential for smart windows and wearable electronics. With excellent stability and high areal capacitance, these fl...
The study investigates the anisotropy dependence of damage evolution and material removal behaviors in ultra-precision machining of MgF2 single crystals. The research team developed a stress field model, revealing that plastic deformation and cleavage fracture mechanisms were activated depending on the crystal orientation.
Researchers found that lncRNA MVIH is overexpressed in cervical cancer tumors and associated with younger age, lymph node metastasis, tumor invasion depth, and squamous cell type. This suggests its potential as a diagnostic biomarker for cervical cancer.
The City of Tempe and Arizona State University have developed a unique partnership to track COVID-19 using wastewater-based epidemiology, providing early warning data for municipalities. The system has been shown to reliably predict SARS-CoV-2 levels in city ZIP codes up to 11 days ahead of clinical testing results.
A new case study explores the early years of BioOne and SPIE's nonprofit platform partnership, highlighting its potential to reduce costs and enhance strategic development. The authors share key lessons learned, including the importance of regular communication and reciprocal service-level agreements.
Researchers found that P2-HNF4α expression is associated with p-STAT3 and c-Myc expression in NAFLD patients, suggesting potential biomarkers for hepatocellular carcinoma (HCC) risk. Additionally, p-STAT3 expression was linked to hypertension, while c-Myc expression was associated with advanced fibrosis.
Researchers developed a photon-efficient volumetric imaging method, laterally swept light-sheet microscopy (iLSLM), which improves axial resolution and optical sectioning while reducing photobleaching. iLSLM outperforms conventional methods like swept focus light-sheet microscopy in terms of resolution and photon efficiency.
Researchers investigated neuronal response to excessive iron accumulation associated with age-related neurodegenerative diseases. They identified two genes, CLU and HERPUD1, that responded to aging-related iron accumulation, highlighting potential preventative strategies.
Research suggests that long-lasting insecticidal malaria nets lost their effectiveness after just one year in Burundi, contradicting the recommended replacement every 3 years. The study found that malaria incidence rose again after two years, highlighting the need for continued epidemiological monitoring and improved resource allocation.
For adrenal lesions evaluated by single-phase dual-energy CT, fat fraction had significantly higher sensitivity than virtual noncontrast attenuation at both clinically optimal threshold and traditional ≤10 HU threshold. Fat fraction-derived metrics can help definitively diagnose incidental adrenal lesions as adenomas.
Researchers review myeloid-derived suppressor cells' phenotypes, mechanisms of immunosuppression, and roles in cancer treatment. Studies on non-malignant diseases, such as autoimmune disorders and obesity, are lacking, highlighting the need for further investigation.
A systematic review of cutting friction behaviors in the metal cutting process reveals its significant impact on tool wear and surface quality. The study contributes to the development of high-quality cutting technology by understanding cutting friction mechanisms, simulation technologies, and anti-friction strategies.
Researchers found that individuals with persistent asthma have higher levels of inflammation and artery plaque, which may increase heart attack or stroke risk. The study also highlights the importance of addressing risk factors for cardiovascular disease in people with persistent asthma.
A study published in Oncotarget found that APOE genotype is associated with the presence and severity of cancer treatment-related side effects and symptoms, as well as the response to exercise-based interventions in cancer survivors. ApoE4 carriers showed a lower fall rate after exercise intervention compared to non-carriers.
A pooled data analysis of 10 randomized controlled trials involving 1040 women found that acupuncture significantly relieved pain during pregnancy, improved physical function, and quality of life. The therapy was also found to be safe, with no observable major side effects for newborns.
A new study analyzed tumor biopsies from patients with newly-diagnosed germinal center B cell lymphoma and found that CREBBP mutations were associated with lower disease-free survival rates. The researchers identified CLMA as a practical tool to translate experimental findings into clinical applications.
The MIT Press and American Academy of Arts & Sciences have made Dædalus, the journal of the American Academy, openly available. This move has led to an increase in online readership and downloads, with over 450,000 essay downloads between 2020 and 2021.
Researchers have summarized the latest developments in mass transfer techniques for large-scale and high-density microLED arrays. The techniques address key challenges such as interfacial adhesion mechanisms and process parameters to achieve high reliability and efficiency.
A new study suggests that prelamin A, a precursor of lamin A, accumulates with age and may drive normal aging. Researchers propose this protein as a target for intervention strategies to extend healthspan and lifespan.
A retrospective study found that tumor hyaluronan levels are associated with improved time to progression in non-small cell lung cancer patients. HA-high tumors showed a trend towards improved clinical benefit, suggesting its potential as a prognostic biomarker and therapeutic target.
A pre-pandemic conspiratorial mindset was associated with hesitance to accept COVID-19 vaccines, a new study suggests. Individuals who held conspiracy theories prior to the pandemic were more likely to believe in COVID-19 conspiracy theories and report hesitancy to be vaccinated.
A study using mRNA and miRNA expression profiles identified molecular signatures that can differentiate muscle invasive bladder cancer patients who respond to neoadjuvant chemotherapy from those who do not. The research found distinct gene pathways and subtypes associated with response, which may lead to more effective treatment delivery.
Research suggests digital marketing of formula milk and commercial baby foods is linked to unhealthy parental feeding practices. Parents exposed to extensive digital marketing were less likely to exclusively breastfeed within the first 6 months and more likely to give their children processed foods and sugary drinks.
Researchers found that overexpressing matriptase reduced myeloma cell proliferation and inhibited migration. Matriptase also blocked Src kinase activation, supporting its potential as a tumor suppressor in multiple myeloma. The study provides new insights into the role of matriptase in hematological malignancies.
The BiCIKL project has reached its halfway stage, launching a European community of key research infrastructures and stakeholders in biodiversity and life sciences. The FAIR Data Place online platform aims to provide scientists with access to all types of biodiversity data 'at their fingertips'.
A recent study published in Oncotarget reveals that Nectin-4 is widely expressed in head and neck squamous cell carcinoma (HNSCC), with significant correlations to clinico-pathological parameters. Non-smokers and p16-positive HNSCC showed higher expression of Nectin-4, leading to better survival rates for positive tumors.
A large UK Biobank study found that poor quality sleep, including insomnia, short/long sleep duration, snoring, and daytime sleepiness, is associated with a heightened risk of developing glaucoma. The study suggests that targeted screening of high-risk groups and sleep intervention may help prevent the disease.
Researchers at Fudan University reviewed fundamental mechanisms and recent developments in selective laser sintering of polymers. The study highlights the need for innovative materials, sintering methods, and post-processing techniques to improve the efficiency and performance of SLS polymer parts.
A study published in BMJ Open found that quad bike injuries among children are significantly more severe and common than car injuries. The research highlights the need for public education campaigns to educate on ATV-related injuries, particularly in young riders.
Researchers analyzed data from bike share stations in NYC, Chicago, and Philadelphia to understand disparities in bike share use. Key findings include concerns about traffic safety and personal safety among lower-income and people of color residents.
A new study published in GigaScience has made available an enormous amount of behavioral data from an animal model of obsessive-compulsive disorder (OCD), comprising over 2 years of continuous recording. The data set, which is the culmination of a 15-year study, provides insights into the mechanisms of OCD and potential treatments.
A new VR gaming technology has been developed that enables players to smell in virtual environments, using an olfactometer that can be printed on 3D printers. This allows for the creation of scent-based game mechanics based on player movements and judgments.
A new platform has been created using 214,000 microbiome samples to track antibiotic-resistant bacteria globally. The data can be used to tailor guidelines on combating resistance in different regions.
Researchers found a strong link between green space and reduced violent and property crime risk across 300 US cities. The study controlled for demographics, poverty, and other factors to confirm the findings.
Research suggests e-bikes won't help users reach weekly moderate to vigorous physical activity targets due to fewer and less physically demanding trips. However, they may encourage older people to take up cycling who wouldn't otherwise do so.
Researchers developed in-situ Ni alloying method to tailor microstructure and enhance strength of LAAM Ti-6Al-4V alloy. The results show that Ni addition increases yield strength and tensile strength while decreasing ductility.
A team of researchers has observed orcas killing white sharks in South Africa using drone and helicopter footage. The study provides the first direct evidence of this behavior, showing that orcas are capable of pursuing, capturing, and incapacitating white sharks.
A Kessler Foundation study found a relationship between rate of cognitive fatigue in MS and microstructural brain changes, particularly in white matter tracts and basal ganglia. The study's findings hold promise for advancing clinical interventions for disabling fatigue.
A prospective multicenter case-control study found that third-trimester fetuses exposed to opioids in utero exhibited smaller brain biometric measurements and altered fetal physiology. The study suggests a possible link between prenatal opioid exposure and postnatal clinical outcomes.
A novel 937-nm laser source has been developed for multiphoton microscopy, enabling deep tissue imaging at depths of over 600 µm with only 10 mW of power. This breakthrough technology offers a good balance between sensitivity, penetration depth, and imaging speed.
The report explores diffuse optical imaging methods applicable to noninvasive human studies, including near-infrared spectroscopy (NIRS) and diffuse correlation spectroscopy (DCS). It introduces state-of-the-art technologies and software, exploring their impact on neuroscience and clinical applications.
A new study sheds light on the ancestry of manatees, tracing their evolution back 47 million years to northern Africa. The research suggests that modern manatees migrated from South America to the Caribbean and North America around 34 million years ago, with some species thriving in communities for millions of years.
Researchers developed a novel biologically-inspired intraoral camera with a wide-angle insect eye structure, increasing field of view and resolving optical aberrations. The device provides multifunctional dental imaging, including high dynamic range, 3D depth, and autofluorescence, without discomfort or image blur.
A review of available monkeypox clinical guidelines found most were of low quality, lacking sufficient detail and failing to cover different risk groups. The lack of clarity between guidelines creates uncertainty for clinicians treating patients with monkeypox.
A 1g reduction in daily salt intake could prevent nearly 9 million cases of heart disease and stroke in China by 2030, saving 4 million lives. This is based on a modelling study that estimates the impact of reducing salt intake across the nation.
Researchers tested a core-strengthening program using the AllCore360º to improve trunk function, balance, and mobility after stroke. The study showed promising effects on functional outcomes, including improved lateral control of posture and standardized treatment dosage.
A Kessler Foundation neuroimaging study found that older individuals reported less state fatigue and showed greater brain activation to combat fatigue. The study also revealed women show greater resilience when faced with a fatiguing task, highlighting age and gender differences in fatigue responses.
A study found that electronic health record (EHR) order entry-based interventions significantly reduced contrast-enhanced CT utilization within a large health system during the global iodinated contrast media shortage. The number of patients undergoing contrast-enhanced CT examinations per day decreased by 12.0%, and the number of orde...
A recent study combined elevation data of the Antarctic ice sheet from two different satellites, CryoSat-2 and Sentinel-3, to obtain a more accurate map of latest elevation changes. The results showed that the average elevation of the ice sheets had decreased at a rate of 4.3 cm/year during 2016-2019.
In India, two out of five eligible children are missing out on preventive vitamin A supplementation, with wide variations in coverage among and within states. The analysis found large 'cold spots' in provision across the country, ranging from just under 13% to 94.5%, and distinct geographical hotspots and coldspots.
Researchers have developed instruments for single-molecule electrochemistry and spectroscopy, aiming to design and synthesize materials with chemistry, physics, and engineering at the atomic scale. They discuss challenges and opportunities in functionalizing molecular junctions and forming stable molecular electronic devices.
Researchers assessed 539 videos from 16 leading food and beverage brands on TikTok, finding that unhealthy food marketing is prevalent among children. The study highlights the need for policies to protect kids from the harmful impact of food marketing on social media platforms.
Researchers discovered Bi2O3 nanoparticles transform into active phase Bi/Bi2O3 nanosheets, showing enhanced catalytic performance and stability. Theoretical calculations support the role of surface-exposed Bi in promoting formate production.
Researchers developed topological membrane metadevices for on-chip terahertz wave manipulations, showcasing robust single-mode manipulation and valley-locked edge states. This breakthrough enables the development of a robust platform for terahertz on-chip communication, sensing, and multiplexing systems.
Researchers developed a novel approach to detecting hidden malicious codes in websites by analyzing common attack patterns and user-side scripts. The method can identify malicious distribution patterns with high accuracy and speed, including zero-day attacks.
The study compares the behavior of flat (1D), cylindrical (2D) and spherical (3D) micromirrors for free-space light coupling. Silicon micromirrors were fabricated and used to experimentally validate the coupling efficiency in visible and near infrared wavelengths.