A five-year study aims to define long-term issues and positive growth in bone marrow transplant survivors, while evaluating factors that impact their survival and quality of life. Researchers will assess physical and psychological health, neuropsychological changes, and menopausal symptoms in over 200 participants.
Researchers at Johns Hopkins Medicine successfully isolated and cultured human embryonic stem cells, a long-sought achievement. The versatile cells have the potential to rapidly study human processes and develop new therapies for various diseases, including diabetes, Parkinson's disease, and muscular dystrophies.
Researchers have developed a method to multiply and mature neural stem cells in the lab, which can form dopamine-producing neurons and reduce symptoms in an animal model of Parkinson's disease. The study opens up new opportunities for studying brain development and may lead to the creation of easily controlled stem cell therapies.
The study found that blood cell precursors originate soon after mesoderm cells appear in the embryo, suggesting a new understanding of blood cell development. The discovery also revealed that definitive red blood cell precursors can be found in the yolk sac before they appear within the embryo.
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A new procedure called in utero stem cell transplantation has shown promise in treating genetic disorders such as sickle cell anaemia and thalassaemia. The technique involves transplanting primitive blood forming cells into an affected fetus, which can cure the disease before damage occurs.
A study by scientists at NIAID found that gene therapy can result in prolonged production of functionally normal white blood cells in patients with chronic granulomatous disease. This finding has important clinical implications for the treatment of this rare immunologic disorder.
Researchers at Duke University Medical Center have identified a cell component called the spectrosome that guides reproductive cells to self-renew and mature differentiated cells in fruit flies. The finding may help explain how men continuously produce sperm and why some stem cells lose control, forming cancerous tumors.
Researchers have developed a new treatment using human mesenchymal stem cells that can regenerate tissue and reduce healing time after tendon surgery. The treatment has shown promising results in animal models, with improved tendon repair strength and quality of tissue within four weeks.
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Researchers are exploring two protocols to tackle AIDS: Protocol 1 focuses on reconstituting immune systems through thymus tissue transplants and boosting T-cells. Protocol 2 involves high-dose chemotherapy, radiation, and blood stem cell transplantation to treat cancer and restore immunity in patients with double jeopardy.