Articles tagged with Stem Cell Research
Researchers at Thomas Jefferson University have isolated hematopoietic stem cells using a specific marker, enabling laboratory production of all types of blood cells. This breakthrough has the potential to alleviate blood shortages for transfusions and develop innovative approaches to bone marrow transplants and gene therapy.
The AAAS study recommends using federal funding for research on human stem cells, including embryonic stem cells already isolated in laboratories. However, the derivation of human stem cells should not receive federal funding due to public anxiety surrounding its process.
The American Association for the Advancement of Science (AAAS) is hosting a public forum to gather public comment on stem cell research recommendations. The event will feature a panel discussion with experts from various fields, including science, ethics, and policy.
Researchers have developed a new method to identify and isolate stem cells from umbilical cord blood using an enzyme that changes a fluorescent tag. This technique could help investigate fundamental questions about stem cells and potentially improve success rates of stem cell transplants by eliminating unwanted mature blood cells.
Researchers at the Weizmann Institute developed a molecule that allows blood stem cells to multiply without differentiation in the test tube, improving bone marrow transplantation and gene therapy research. This breakthrough could enable scientists to insert genes into human stem cells for treating genetic disorders.
Researchers at University of Washington successfully grew large numbers of mouse blood stem cells in lab for up to four months. The discovery may allow better care of cancer patients and create possibilities for genetic cures by enabling the multiplication of blood stem cells outside the body.
A Brown University research team has identified primary signals that initiate liver formation in embryonic cells. Understanding these signals could lead to new treatments for diseases such as viral hepatitis and cancer by enabling tissue regeneration and reprogramming of diseased cells.
Researchers will discuss cellular interactions in prostate cancer, new gene discoveries, and techniques for measuring patient outcomes. The symposium also features presentations on experimental agents, immunotherapies, and alternative therapies for treating prostate cancer.
Researchers found that vaccinated patients had a significantly lower chance of death and relapse compared to non-vaccinated patients. The THERATOPEO vaccine increased specific killing activity against cancer cells, leading to longer remission periods.
Researchers at UT Southwestern Medical Center have developed a novel method to turn off genes involved in telomerase activation, which enables continuous cell division in cancer cells. The study used peptide nucleic acid (PNA) molecules to block telomerase activity, showing significant promise for developing new cancer drugs.
The American Society of Transplantation will present over 1,000 presentations on various transplantation topics, including new findings on liver splitting for child recipients and embryonic stem cell transplantation. The conference also explores advancements in treating post-transplant patients without steroids and lung transplantation...
Bone marrow stem cells have been shown to form liver cells, suggesting a potential new approach for treating cirrhosis. Researchers at McGill University in Quebec discovered that cells from bone marrow can differentiate into hepatocytes, oval cells and bile duct cells.
Researchers discovered that human stem cells use a specific receptor, CXCR4, to migrate to bone marrow. Treating stem cells with growth factors increased their ability to express this receptor and migrate successfully, improving transplant success rates from 25% to over 90%.
A new study finds that certain brain cells can be stimulated to regenerate following a stroke, potentially treating memory disorders in stroke patients. Researchers discovered a 12-fold increase in the birth of new cells in rodents after stroke, which may lead to rewireing the brain and helping survivors recover lost memory function.
University of Pittsburgh researchers isolated bone-precursor cells from skeletal muscle and genetically altered them to produce bone growth. Injecting these cells into mice showed they could form bone inside the animals. This discovery may lead to targeted treatments for incomplete fractures.
Researchers have discovered a way to reprogram cells, enabling the selective expression of genes. This breakthrough could lead to new treatments for diseases by harnessing this technology to turn off or on specific genes in different cell types.
Human neural stem cells have been cloned for the first time in a solid organ, validating decades of research on mouse cell biology. These cells hold potential for future therapies in conditions like Tay-Sachs disease and brain cancer.
Researchers have found that adult stem cells, previously thought to be permanent, can shed their identities and become blood cells. This discovery raises the possibility of using adult stem cells for therapeutic purposes, such as generating healthy blood cells for patients with blood disorders.
Research reveals that the AHC gene, previously thought to program ovarian development, is actually crucial for male fertility. Males lacking this gene have defective testicles and are sterile. The study also found that overexpression of the AHC gene can interfere with the function of a key protein involved in testicular development.
Researchers demonstrate that human cells grown in the laboratory and immortalized by telomerase are not transformed into cancer cells, exhibiting normal behavior despite extended lifespan. The findings hold promise for new therapies for age-related diseases and cancer.
High-dose cyclophosphamide treatment achieved complete remissions in five patients with autoimmune disorders, while partial remissions were maintained in two. Patients experienced improved kidney function and reduced medication doses.
Scientists have developed a novel gene therapy treatment that permanently blocks age-related loss of muscle size and strength in mice. The treatment increases muscle strength by up to 27% in older mice, fully restoring their strength to young adulthood.
A clinical trial demonstrates that TPO, administered with G-CSF, boosts stem cell migration and increases the number of patients eligible for autologous stem cell transplantation. The treatment significantly improves re-growth of blood cells after chemotherapy.
A phase I trial has shown that adding mature stem cells to an umbilical cord blood transplant increases the success rate of transplants in children. The 'booster' cells were given to patients after growing in a laboratory setting for 12 days, and 19 out of 28 patients had successful transplants.
A five-year study aims to define long-term issues and positive growth in bone marrow transplant survivors, while evaluating factors that impact their survival and quality of life. Researchers will assess physical and psychological health, neuropsychological changes, and menopausal symptoms in over 200 participants.
Researchers at Johns Hopkins Medicine successfully isolated and cultured human embryonic stem cells, a long-sought achievement. The versatile cells have the potential to rapidly study human processes and develop new therapies for various diseases, including diabetes, Parkinson's disease, and muscular dystrophies.
Researchers have developed a method to multiply and mature neural stem cells in the lab, which can form dopamine-producing neurons and reduce symptoms in an animal model of Parkinson's disease. The study opens up new opportunities for studying brain development and may lead to the creation of easily controlled stem cell therapies.
The study found that blood cell precursors originate soon after mesoderm cells appear in the embryo, suggesting a new understanding of blood cell development. The discovery also revealed that definitive red blood cell precursors can be found in the yolk sac before they appear within the embryo.
A new procedure called in utero stem cell transplantation has shown promise in treating genetic disorders such as sickle cell anaemia and thalassaemia. The technique involves transplanting primitive blood forming cells into an affected fetus, which can cure the disease before damage occurs.
A study by scientists at NIAID found that gene therapy can result in prolonged production of functionally normal white blood cells in patients with chronic granulomatous disease. This finding has important clinical implications for the treatment of this rare immunologic disorder.
Researchers at Duke University Medical Center have identified a cell component called the spectrosome that guides reproductive cells to self-renew and mature differentiated cells in fruit flies. The finding may help explain how men continuously produce sperm and why some stem cells lose control, forming cancerous tumors.
Researchers have developed a new treatment using human mesenchymal stem cells that can regenerate tissue and reduce healing time after tendon surgery. The treatment has shown promising results in animal models, with improved tendon repair strength and quality of tissue within four weeks.
Researchers are exploring two protocols to tackle AIDS: Protocol 1 focuses on reconstituting immune systems through thymus tissue transplants and boosting T-cells. Protocol 2 involves high-dose chemotherapy, radiation, and blood stem cell transplantation to treat cancer and restore immunity in patients with double jeopardy.