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Science News Archive 2004 - Page 12


Page 12 of 135

JCI table of contents, December 1 2004

Researchers at Columbia University have discovered a new treatment that improves memory in mice with Alzheimer's disease. The phosphodiesterase inhibitor rolipram was found to modify gene expression and make brain synapses more resistant to beta-amyloid accumulation.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateDec 1, 2004

Spider silks, the ecological materials of tomorrow?

Researchers are exploring spider silk's potential as an ecological material, with applications in wound-closure systems and durable surgical implants. By engineering artificial proteins, they hope to create intelligent materials that can assemble into new types of mesh with biochemically active groups.

SourceBMC (BioMed Central)·JournalMicrobial Cell Factories·DateNov 30, 2004

The logic of life brings order to our genes

Professor Carsten Peterson and his team demonstrate how genes interact to produce stable systems, using the fruit fly as a model organism. They found that canalyzing rules, where one controlling gene activates another without affecting it, are present in almost 200 genetic networks in fruit flies.

SourceSwedish Research Council·JournalProceedings of the National Academy of Sciences·DateNov 30, 2004

Hebrew University researcher finds 'sweet' way to help prevent heart disease

A recent study published in Journal of Agricultural and Food Chemistry found that drinking pomelit juice daily can lower LDL blood cholesterol and increase antioxidant activity. Hypercholesterolic patients may benefit from adding fresh Sweetie juice to their diet as a preventative measure against future heart disease.

SourceThe Hebrew University of Jerusalem·JournalJournal of Agricultural and Food Chemistry·DateNov 30, 2004

Mayo Clinic discovers potential marker for aggressive kidney cancer

Researchers at the Mayo Clinic have identified a potential biomarker for aggressive kidney cancer, which can help improve treatment outcomes by identifying patients at high risk of disease progression. The study found that high levels of B7-H1 molecule are associated with increased risk of cancer spread and mortality.

SourceMayo Clinic·JournalProceedings of the National Academy of Sciences·DateNov 30, 2004

'Lighter than air' breathing more than doubles COPD patients' exercise endurance

A low-density helium/oxygen mixture significantly reduces airflow limitations and lung dynamic hyperinflation in COPD patients, allowing for a substantial increase in exercise endurance time. The study found that the duration of exercise doubled from 4.2 minutes to 9 minutes for patients breathing heliox compared to regular air.

SourceAmerican Physiological Society·JournalJournal of Applied Physiology·DateNov 29, 2004

Columbia researchers identify drug as therapeutic candidate for spinal muscular atrophy

Researchers at Columbia University have identified indoprofen as a potential therapeutic candidate for spinal muscular atrophy (SMA), a neurodegenerative disease affecting thousands of children worldwide. The discovery was made using a high-throughput chemical genetics approach and involves the use of a novel analysis tool called SLIMS.

SourceColumbia University Irving Medical Center·JournalChemistry & Biology·DateNov 29, 2004

New pheromone creates buzz about the clout of older bees

Researchers at Michigan State University have identified a new pheromone that regulates the behavioral maturation of honey bees, keeping younger nurse bees in check until they are more mature. This discovery sheds light on the complex social dynamics within bee colonies and how older forager bees exert influence over younger bees.

SourceMichigan State University·JournalProceedings of the National Academy of Sciences·DateNov 29, 2004

Alliance congratulates Congress and NIH

The Alliance for Taxpayer Access congratulates Congress and NIH on their public access plan, which aims to make taxpayer-funded biomedical research accessible online at no extra cost. The plan's compromise approach balances publisher interests with public access, addressing the 'Fleecing of America' issue highlighted by NBC News.

Testosterone deficiency found in one-third of diabetic men

A recent study revealed that nearly one-third of diabetic men suffer from hypogonadism, a condition caused by improper functioning of the pituitary gland or hypothalamus. The high prevalence of low testosterone levels in diabetic patients is concerning and associated with various health issues such as loss of muscle tone, increased abd...

SourceUniversity at Buffalo·JournalThe Journal of Clinical Endocrinology & Metabolism·DateNov 29, 2004

Differences in gene usage dramatically change bacteria's 'lifestyles'

Scientists found significant differences in Salmonella and E. coli's use of a gene linked to processes that govern antibiotic resistance, altering their ability to survive in different environments. The study suggests that understanding such changes will help develop new treatments for disease-causing microorganisms.

SourceWashU Medicine·JournalProceedings of the National Academy of Sciences·DateNov 29, 2004