Researchers identified a new mechanism by which HRG protein inhibits angiogenesis and tumor growth in cancer patients. The study shows that the HRG fragment binds to endothelial cells and platelets, creating a microenvironment that functions as an angiogenesis inhibitor.
Researchers have devised a new way to disarm the key protein NOTCH, which drives tumor growth. The discovery lays the foundation for a new therapy aimed at critically important transcription factors that could treat various diseases, including multiple types of cancer.
Researchers at the University of Leeds have developed a new technology to ensure correct drug crystal formation, eliminating polymorphism issues that result in significant losses. The system uses self-assembled monolayers to produce well-defined crystal structures, promising improved pharmaceutical efficiency and efficacy.
Scientists have assembled the largest-ever collection of liver proteins, which could become a roadmap for finding new biomarkers and treatments for liver disease, including hepatitis. The database includes 6,788 non-redundant proteins, many of which are related to diseases in the nervous system.
A study of 234 male college athletes found those using performance-enhancing substances were more likely to admit to heavy drinking and recreational drug use. They also experienced elevated rates of substance-related problems, including missing classes or getting into fights.
The UK research community has secured £7.5 million in funding to study the development and spread of pandemic influenza H1N1 2009. The projects aim to understand how the virus mutates, jumps species barriers, and causes disease in humans and pigs.
K-State's Fred Cholick, Dean of the College of Agriculture, received the Agronomic Service Award for his development of agronomic service programs and practices. Dave Mengel, Professor of Agronomy, won the Werner L. Nelson Award for his outstanding performance in diagnostic techniques and approaches.
The K-State Environmental Leadership Program develops an interdisciplinary course curriculum addressing water quality issues and civic engagement in watershed restoration. The program aims to build capacity in addressing environmental issues through a $114,000 grant from the US Department of Agriculture.
Researchers discovered that Stapled Peptides can potently and directly inhibit the Notch transcription factor complex, preventing cancer cell proliferation and survival. The findings validate the potential of Stapled Peptides to modulate key intracellular biological targets.
Researchers found features in rocks from the Buck Reef Chert that suggest water temperatures were significantly lower than previous studies had suggested, making conditions for life easier. This discovery could change our understanding of the earliest forms of life on Earth and potentially reveal new ways to study the planet's history.
Researchers found that employees participating in a large-scale worksite wellness program had significantly reduced absenteeism days due to illness. The study also estimated cost savings of $414.90 per employee per year.
A recent study published in the Journal of Vascular and Interventional Radiology found that catheter-directed therapy is a relatively safe and effective treatment for acute massive pulmonary embolism. The treatment was lifesaving in 86.5% of cases studied and had only a 2.4% chance of major complications.
A Kaiser Permanente study found that workers exposed to high levels of Bisphenol-A (BPA) in their jobs had a quadruple the risk of erectile dysfunction and seven times more risk of ejaculation difficulty. This is the first human study to measure the effects of BPA on the male reproductive system.
Scientists develop a new method to study living cells by exploding them with laser pulses, then analyzing the vaporized contents for chemical profiles. This technique reveals crucial details about cell health and differences between diseased and healthy cells.
The software converts flat medical scans into 3D images, making it easier for doctors to plan surgeries or radiation therapy. The technology is also being used in school biology classes to engage students and teach anatomy.
A new study reveals a novel mouse gene that reduces Alzheimer's disease pathologies by interacting with a key cellular enzyme. The research found that the gene, Rps23r1, interacts with glycogen synthase kinase-3 (GSK-3) and inhibits its activity, resulting in improved AD-like pathologies in transgenic mice.
A team of mathematicians has developed a method to design underground lines that bypass historical monuments, minimizing economic loss and ensuring safe distances. The study applies Voronoi diagrams to create optimized routes, offering non-disruptive solutions for the construction of line 2 in Seville.
The Interagency Autism Coordinating Committee (IACC) has included vaccine research studies in its updated Strategic Plan for Autism Research, responding to Congressional calls to investigate the potential connection between vaccines and autism. The plan aims to explore risk factors contributing to autism, including environmental exposu...
A new Stanford University study suggests the early ocean was much more temperate and life likely diversified and spread across the globe sooner. The researchers analyzed isotope ratios in ancient rocks, finding that the ocean temperature could not have been more than 40C, contradicting previous estimates of at least 55 degrees Celsius.
The SUNRISE balloon-borne telescope has delivered images showing the complex interplay on the solar surface with unprecedented detail. The mission reveals a connection between magnetic field strength and solar brightness, with implications for Earth's heat input.
Research found four alterations in RORB gene associated with pediatric bipolar disorder, linking circadian rhythm abnormalities to the condition. The study suggests that clock genes may be important candidates for further investigation into bipolar disorder's molecular basis.
Researchers have engineered bowtie-shaped devices that focus and sort light in tiny spaces, enabling the creation of ultrafast detector arrays. By introducing asymmetry, scientists can control the plasmonic properties of these devices to produce filters with specific colors or energies.
UT Southwestern Medical Center has launched ResearchMatch, a national partnership to match volunteers with scientists leading medical research studies. The initiative provides access to clinical trials and studies across the country, while protecting participants' privacy.
A Kansas State University study found that adolescents are less likely to wash their hands when cooking and more susceptible to cross-contaminating raw foods. Researchers also discovered that even with provided instructions, many consumers don't follow food safety guidelines.
Researchers at Albert Einstein College of Medicine discovered a link between longevity and genes that maintain telomere length. The study found that individuals with long telomeres were more likely to have inherited genes that enabled effective telomerase production, potentially protecting against age-related diseases.
A new miniature microscope enables neurosurgeons to visualize brain tumors in real-time, allowing for more precise removal and accurate diagnosis. This technology has the potential to reduce surgery time by up to 40 minutes and improve patient outcomes.
A study of Mexican swine flu cases reveals that young people are most likely to get infected, while the elderly have the highest mortality rates. The study also found that vaccination significantly lowers infection risk and prompt treatment is crucial for pregnant women.
A clinical trial found that eating about an ounce and a half of dark chocolate daily for two weeks reduced stress hormone levels and corrected other stress-related biochemical imbalances. This study provides strong evidence for the potential benefits of dark chocolate in reducing emotional stress.
A study by RAND Corporation suggests that slowing US healthcare spending will require new approaches, including changing payment methods for doctors and hospitals. The most promising option is bundling payments for medical care, which would encourage providers to eliminate unnecessary care and improve quality.
Children with dyslexia have trouble distinguishing speech from noise due to a deficit in the brain's ability to focus on predictable voice pitch. This mechanism is crucial for segregating sound streams and excluding background noise, a common symptom of dyslexia.
A DNA study confirms that Africa's rarest monkey, the kipunji, had an intriguing sexual past with baboons. The results may help to set conservation priorities for this critically endangered species by highlighting the importance of protecting its habitat and preserving genetic diversity.
A Mercyhurst forensic anthropology team conducts a mock excavation to test methods for recovering burned human remains from fatal fire scenes. The project aims to improve protocols for optimal scene recovery and laboratory analysis.
The University of Rochester Medical Center has launched a new center to improve cardiac safety and understand cardiac arrhythmias. The center will utilize a vast database of ECG data to develop novel methods and technologies to predict cardiac arrhythmias.
A team of researchers from Emory University, Children's Healthcare of Atlanta, and Georgia Tech has developed a novel continuous renal replacement therapy device designed specifically for children. The device addresses safety concerns and size limitations associated with adult kidney dialysis equipment, which can lead to dehydration an...
Researchers at Max Planck Institute create a novel catalyst that efficiently converts methane to methanol, offering a cost-effective alternative to traditional methods. The breakthrough could help address global natural gas shortages and support the chemical industry.
A UCLA/Emory study discovered significant differences between the human and chimp versions of the FOXP2 gene, which may explain why humans developed language while chimps did not. The research provides insight into the evolution of the human brain and may lead to new drug targets for disorders characterized by speech disruption.
Phillip A. Sharp has been awarded the 2010 Herbert Tabor Lectureship for his groundbreaking research on small RNAs, RNA interference, and its potential to revolutionize biology and generate new therapeutics. Sharp's work builds on his landmark discovery of RNA splicing in 1977, which earned him a Nobel Prize in Physiology or Medicine.
A study demonstrates the effectiveness of a gene delivery strategy producing follistatin, which inhibits myostatin, in non-human primates, showing pronounced increases in muscle size and strength. The treatment is well-tolerated and has long-term effects, paving the way for potential clinical trials.
Researchers found that aisle placements can influence sales across product categories as much as price or display. Stores placing cross-category items like chips and soda facing each other in the same aisle saw a 9% increase in weekly sales. This benefits both retailers and consumers.
Astronomers have discovered that Sun-like stars with planetary systems tend to have lower levels of lithium than those without planets. The study, which analyzed 500 stars, found that planet-bearing stars had less than 1% of the lithium present in other similar stars.
University of California, Berkeley chemists use ultrafast laser pulses to study green fluorescent protein's structural changes during fluorescence. The study reveals the importance of vibrational oscillations in proton transfer reactions, shedding light on how GFP captures and emits light.
Research from Northwestern University's Auditory Neuroscience Laboratory confirms that children with developmental dyslexia have trouble tuning into relevant auditory signals. The study suggests that poor readers who struggle with processing sound in noisy environments may benefit from simple strategies to enhance their listening skills.
A survey of 30 pediatric physicians reveals differing views on the role of religion and spirituality in medicine, with some seeing it as a barrier to care and others as a bridge. The study found that pediatric oncologists are more likely to view patients' religious backgrounds as relevant to their treatment.
A team of researchers, led by Iowa State University's Adam Bogdanove, has made a groundbreaking discovery about the molecular basis of bacterial diseases in plants. They found that specific proteins bind to host DNA molecules at predictable locations, activating targeted genes.
The analysis found that hazard ratios for vascular disease were nearly identical with non-HDL-C and HDL-C measurements as those seen with apo B and apo AI. Moreover, triglyceride concentration was not independently related to CHD risk after controlling for HDL-C and total cholesterol levels.
Researchers have discovered up to 15 species of boneworms in Monterey Bay, which feed on dead whales and exhibit unique life cycles. The worms' ability to adapt to different environments and find food sources has led scientists to estimate their evolutionary origins, suggesting they may date back to the time of dinosaurs.
Researchers at Rice University and the Texas Heart Institute will label stem cells with gadonanotubes to track their effectiveness in regenerating damaged heart tissue. The team aims to use MRI to steer the cells in vivo with an external magnetic field.
UC San Diego engineers develop algorithms for swarms of ocean robots to track ocean currents, predict oil spill movement, and improve models. The system will enable local agencies to deploy robots quickly to monitor spills and aid in the development of marine protected areas.
Researchers at Karolinska Institutet have discovered a mechanism that controls the brain's ability to create lasting memories. The study found that signalling via the nogo receptor 1 plays a key part in this process, enabling the conversion of short-term memories into long-term ones.
Experts from 11 countries agree on a joint DNA-based database to combat child trafficking, with the goal of eradicating the crime. The DNA-Prokids Programme aims to reunite victims with their families and prevent further exploitation.
A study published in the Journal of the National Cancer Institute found that erythropoiesis-stimulating agents increase the risk of venous thromboembolism in cancer patients. The use of these agents, approved to reduce blood transfusions during chemotherapy, may outweigh benefits due to associated risks.
A study of 3,754 women found that nearly 50% experience pain symptoms 2-3 years after breast cancer treatment, with young age and supplemental radiation therapy increasing the risk. The most common areas affected by pain are the axilla, arm, breast area, and side of the body.
Astronomers have found a middleweight black hole in galaxy NGC 5408, with masses between 1,000 and 9,000 solar masses. The discovery was made using the Swift satellite and XMM-Newton observatory, which detected quasi-periodic oscillations from the black hole.
A recent study found that only 30% of chest pain patients were seen within the recommended 10-minute timeframe, with African Americans facing longer wait times. Caregiver support and discipline also played a significant role in reducing adolescents' risk-taking behaviors.
Researchers at UAB used fMRI to analyze the brain's response to surprising sounds, finding activity in the frontal lobe controls emotional expression. The study aims to develop biological markers using fMRI that can help identify and treat PTSD sufferers.
Clemson University is part of a five-year, $3 million Air Force Office of Scientific Research award to explore carbon nanotube-based superconductors. The team aims to develop composite wires that can replace inefficient copper wiring in power lines.
A large observational study found that long-term statin use is associated with a decreased risk of developing gallstones requiring surgery. Patients taking statins for 1-4 prescriptions had a lower risk compared to non-users, with an increased risk reduction after 5 prescriptions.
A study by Fred Hutchinson Cancer Center found that women with cancer diagnoses are six times more likely to separate or divorce than their male counterparts. Longer marriages also remain more stable, with age being a factor in the likelihood of divorce or separation.
A new study reveals that the healthcare industry in the US accounts for nearly 10% of the country's total carbon dioxide emissions, despite only accounting for 16% of the nation's gross domestic product. Hospitals and pharmaceutical industries are among the largest contributors to this environmental impact.
The Geisel School of Medicine at Dartmouth has launched a handbook for rural health care ethics, addressing the gaps in resources for regional clinicians. The guide covers case studies and personal ethical challenges faced by healthcare professionals in rural settings.