A 3-month course of levofloxacin following kidney transplantation did not prevent BK virus from appearing in the urine, according to a study. The intervention was associated with increased risk of adverse events like bacterial resistance.
Researchers found that peritoneal dialysis and high-frequency home hemodialysis can significantly reduce mortality risks. Patients receiving these treatments had 10-26% lower mortality rates than those with standard in-center hemodialysis.
Recent high-impact clinical trials have yielded promising results in the fight against kidney disease, with several treatments showing significant benefits in reducing the risk of end-stage kidney disease. For example, intensive glucose control has been shown to lead to long-term reductions in the risk of developing end-stage kidney di...
A recent study forecasts the immense economic cost of osteoporotic fractures in China, expected to double by 2035 and reach $25.58 billion by 2050 due to an aging population.
A chemotherapy regimen of procarbazine, CCNU, and vincristine (PCV) following radiation therapy improved progression-free survival and overall survival in adults with low-grade gliomas. This trial found patients with oligodendroglioma had better outcomes than those with astrocytoma or oligoastrocytoma.
Late-breaking clinical studies presented at ASN Kidney Week 2014 highlight significant advances in kidney care, including the reduction of disparities in transplant referrals through a community-based intervention. Additionally, new treatments for End-Stage Renal Disease (ESRD) have shown promising results, such as ferric citrate's abi...
Studies found significant disparities in access to pre-ESRD kidney care across the US, with certain geographic areas and racial groups receiving lower quality care. Disparities were more pronounced among black patients, who had a 10% to 54% lower odds of receiving care from a kidney specialist.
A study found that sleep apnea is associated with more rapid loss of renal function in patients with diabetic nephropathy. Researchers identified high-risk scores for obstructive sleep apnea, which were common in non-dialysis CKD patients and linked to decreased kidney function.
A study found that Boston Marathon bombings resulted in over 100 cases of ear and hearing injuries, with 80% of patients experiencing reduced hearing and 68% new or worsened tinnitus one year later. Many had difficulty hearing in noisy situations and ongoing disability related to hearing loss, tinnitus, or dizziness.
A groundbreaking study by UCSF researchers found elevated carcinogen markers in nonsmoking car passengers after exposure to secondhand smoke. The study suggests that simply sitting in cars with smokers can lead to increased levels of toxic compounds associated with cancer, heart disease, and lung disease.
The MIT researchers' model assumes that large groups of ratings can be clustered together and described probabilistically. They found that just five clusters were enough to account for most of the variation in a population, suggesting that collaborative filtering yields nearly optimal predictions.
Researchers at Cardiff University have built a theoretical model to predict potential gravitational-wave signals from black hole collisions. The model aims to help scientists identify the correct waveforms and reveal secrets about how black holes orbit and collide.
A study found that 55% of the US population is not eligible to donate a kidney due to preventable health conditions such as hypertension, obesity, and diabetes. The majority of individuals with lower incomes are less likely to donate due to financial difficulties and immigration status.
Exercise training slows kidney function decline and improves cardio-respiratory fitness in patients with progressive stages 3–4 CKD. A personalized, low-intensity home exercise program also improves physical performance in dialysis patients.
Researchers at Cancer Research UK have identified over 400 areas of hidden faults in the human genome, which could conceal cancer-causing gene mutations. These 'blind spots' are difficult to detect using current gene-reading technology, highlighting opportunities for new diagnostic tests and treatments.
Researchers developed an anti-cancer drug that protects normal cells from radiation damage while sparing cancer cells. The compound, RTA 408, increases the effectiveness of radiation therapy in prostate cancer models and has potential applications for treating accidental radiation exposure.
Researchers at Vanderbilt University have discovered a new form of crystalline order that exhibits both crystal and polycrystalline properties. The 'interlaced crystals' arrangement has ideal properties for thermoelectric applications, which could increase power generation efficiency and reduce energy costs.
Researchers developed a fluorescence imaging technique to accurately identify protein receptors in tumors without tissue biopsy. The new approach strongly correlates with clinical immunohistochemistry and may impact oncology patient outcomes.
Research from University of Eastern Finland finds SIP1 protein expression indicates advanced tumour stage, high recurrence risk, and poor prognosis. The study identifies SIP1 as a potential new prognostic factor for clinical use.
Two new studies suggest that smartphones can be a key tool in improving medication adherence among teens and young adults with chronic conditions. Researchers found that patients who used cell phones for reminders were more likely to have 100% self-reported medication adherence, while those involved in a dedicated Young Adult Service h...
The 2014 global ocean warming is a result of North Pacific's record-breaking warming and the release of heat from stored water in the Western tropical Pacific. Temperatures now extend along the North American coast, indicating an end to the 14-year-long pause in ocean warming.
Researchers at the University of Toronto found that personalized dietary advice based on a person's genetic makeup leads to better eating habits and significant reductions in sodium intake. The study, published in PLoS One, suggests that genetic testing can improve lifestyle changes by providing tailored food recommendations.
Researchers at the University of Georgia discovered that chlorogenic acid significantly reduced insulin resistance and fat accumulation in mice fed a high-fat diet. The compound also maintained normal blood sugar levels and healthy liver composition.
Conventional treatments such as surgery and radiotherapy are less effective in prostate cancer patients carrying BRCA mutations, resulting in lower survival rates. The study suggests that targeted therapy, like PARP inhibitors, may be a more suitable option for these patients.
The study using Google Analytics found that online plant databases are visited by users in over 100 countries, with mobile traffic growing steadily. This highlights the democratization of botanical information, equal access for researchers worldwide, and reduced wear on biodiversity objects.
A new smartphone app developed by Rutgers engineers helps Warren Township document and mitigate hundreds of hazards to power lines, reducing the risk of future power outages. The app uses crowdsourcing to gather data from volunteers, which is then presented to utility companies in an organized manner.
A study found that weight loss after bariatric surgery is associated with increased kidney function and decreased albuminuria, a marker of kidney dysfunction. This suggests a beneficial impact on kidney health for patients with and without baseline kidney disease.
The Healthy Heart Score uses data from large-scale studies to estimate an individual's 20-year CVD risk based on nine critical diet and lifestyle factors. The free web-based survey provides practical tips for improving scores by incorporating heart-healthy habits into daily life.
Researchers at the University of Manchester have identified factor H-like protein 1 (FHL-1) as a new target for treating age-related macular degeneration (AMD). The study suggests that insufficient FHL-1 in the eye's back may lead to inflammation and vision loss.
Researchers at the University of Helsinki have uncovered a new regulatory system that senses nutrient deprivation and inhibits growth in fruit flies. This system, which involves protein kinase ERK7, prevents secretion of insulin-like peptides during starvation.
For the first time, clinicians have successfully provided hemodialysis to a patient with Ebola virus disease, resulting in recovery of kidney function. The protocol involved careful measures to maximize safety and minimize risk of secondary transmission, demonstrating that renal replacement therapies can be provided safely.
Glaucoma, affecting over 60 million worldwide, has been linked to mitochondrial gene mutations through DNA sequencing. The research aims to support personalized medicines targeting mutated mitochondria and prevent disease progression.
A study by Mass Eye and Ear found that blast-related ear injuries caused significant morbidity in Boston Marathon bombing survivors. The researchers reported high rates of hearing loss, tinnitus, and dizziness-related quality of life impairment among the patients.
A recent study by University of Leicester researchers found a higher number of fast-food outlets within 500m of inner-city neighbourhoods with high-density non-white ethnic minority groups and socially deprived areas. The study suggests a postcode lottery that increases the risk of developing diabetes or obesity.
A new study from the University of East Anglia finds that a single high level of lithium can cause significant decrease in kidney function, which remains affected for up to nine months. The research emphasizes the importance of regular monitoring, supporting current UK guidelines.
Researchers at UT Southwestern Medical Center found a novel looping mechanism involving DNA end caps that determines gene regulation, contributing to aging and disease. The study reveals how telomere length affects gene expression patterns, potentially influencing the onset of disease and optimizing fitness with age.
A new study reveals a stark assessment of the health dangers faced by male sex workers in Mexico City, with 38% having HIV and 21% having syphilis. The study highlights the need for incentives to promote condom use and improve individual and population health.
Dr. Alford has made significant contributions to health education through his work at Boston University School of Medicine. He received the AMA Award in recognition of his dedication and impact on healthcare education.
A mathematical model predicts that around 10 of 29 people with Ebola are likely to be detected at airport screening when trying to travel from West Africa to the UK and US by the end of the year.
A study of 699 African American adults found that those with severe periodontal disease developed chronic kidney disease at a rate 4 times higher than those without. Targeting periodontal disease may be an important path towards reducing disparities in chronic and end-stage kidney disease.
Researchers created a three-dimensional model of a single neuron to study its electrical properties. The study found that changes in cell morphology affect hyper-excitability, highlighting a new relationship between cellular dysfunction and structural integrity.
Youngsters with diabetes are more inclined to perform tasks related to their condition when prompted by a friendly interactive robot. The ALIZ-E project has shown that social robots can assist children with other medical conditions and act as classroom assistants, improving learning outcomes.
A position paper by ESPGHAN Hepatology Committee outlines recommendations and a checklist for liver biopsy in infants and children. Liver biopsy is still necessary in follow-up after liver transplantation and for monitoring disease activity.
A new study found that teen drivers who start class earlier in the morning are involved in significantly more motor vehicle accidents. The results suggest that early high school start times contribute to teens' reduced sleep and increased risk of drowsy driving accidents, including run-off-road crashes.
Researchers developed a method to securely display 3D images on smartphones by scanning QR codes without accessing the Internet. The system uses integral imaging and encryption to protect data, ensuring only authorized devices can access the content.
Scientists found 12 caves with trechine beetles, 7 new species, and 103 samples collected, highlighting the Du'an Karst as a biological hotspot for cavernicolous Trechinae in China.
Researchers at University of Guelph found a potential breakthrough in treating late-stage ovarian cancer by shrinking tumours and improving drug delivery. This approach may lead to novel treatment options with reduced morbidity and mortality.
A new international study led by the Research Institute of McGill University Health Centre has identified a molecule that puts a brake on brain processing and when removed, brain function and memory recall are improved. The study found that suppressing the production of molecules required for building new memories leads to stronger con...
Researchers at Lund University have identified a mechanism that creates cold-induced pain, linking it to the same receptor that reacts to pungent substances in mustard and garlic. This discovery could help those with cold allodynia, a common problem among patients with chronic pain or nervous system diseases.
Researchers have developed a new method to predict illegal fishing patterns in offshore marine reserves, enabling authorities to better protect these areas. The study, which analyzed data from the Cocos Island National Park, identified hotspots and lunar phases associated with illegal fishing, allowing for more targeted patrols.
Astronomers find compact, young galaxies shut down their prodigious star production due to a lack of cool dense gas, rather than supermassive black holes. The energy from the star formation itself creates a shortage of gas within the galaxy.
Researchers found high genetic diversity in thousand cankers disease fungus, making it harder to control. The fungus is native to the US and has mutated readily, leading to an explosion in its impact on host trees.
A research project has been awarded for its innovative approach to stopping bone destruction and tooth loss in severe gum disease. The study aims to re-programme the immune system to fight bacteria without damaging healthy tissue, thereby halting bone destruction before it advances.
Scientists have found that self-doping in the copper-based material YBCO enables it to conduct electricity without loss at room temperature. This groundbreaking discovery challenges traditional understanding of high-temperature superconductivity and could pave the way for more efficient electrical applications.
A recent study found that feelings of disgust can increase behaviors like lying and cheating, while cleanliness can help people return to ethical behavior. The researchers used three randomized experiments to test the impact of emotions on decision-making.
Researchers at Sentient Science and University at Buffalo develop wearable technology to measure stress, fatigue, and resilience. The system sends personalized alerts to prevent heart attacks and physical injuries.
Researchers discovered a plant protein, KEA3, crucial for adjusting photosynthetic efficiency in fluctuating light conditions. This mechanism enables plants to quickly respond to changes in light intensity and maintain high energy capture.
Smoking increases susceptibility to TB infection, with white blood cells in smokers' lungs showing a weakened response to the disease. The discovery provides new insights into treating and preventing TB, which kills 1.5 million people annually.
The Ebola pandemic serves as a stark reminder of the interconnectedness of human, animal, and environmental health. The study emphasizes the urgent need to adopt a One Health approach to detect and prevent infectious diseases, particularly in developing countries.
Researchers created a global model of CO2 uptake using fine-scale observations, finding strong interannual variations and the Pacific Ocean dominating flux variability. The study's lead author notes that shipboard measurements provide key data for estimating ocean CO2 sink variability.