Researchers found that adding retinoic acid to standard-of-care treatment for melanoma can turn off myeloid-derived suppressor cells (MDSCs) that resist immune treatments, leading to increased immune system activity. The study showed a safe and promising strategy to target MDSCs, which could be a useful addition to immunotherapies for ...
The Hastings Center report explores advanced care directives for dementia patients, childhood obesity, and patient demands for specific healthcare providers or racial/ethnic backgrounds. Competent individuals should have control over life-sustaining treatments, while environmental factors contribute to childhood obesity.
Researchers at Purdue University have developed a method to produce multiple colors simultaneously on an electronic chip, enabling broader bandwidth for sensing and processing information. This breakthrough could lead to advancements in nanophotonics, bio-sensing, and imaging applications.
A recent UTHealth-led survey revealed that only 19.3% of healthcare organizations in the US and Australia have fully implemented voluntary guidelines for safe e-health record management. The study found significant variation in adherence rates across different domains, suggesting factors such as budget constraints, personnel skill mix,...
The Woods Hole Oceanographic Institution (WHOI) will provide seafloor seismographs and technical support under a new cooperative agreement, starting August 1, 2018. The OBSIC replaces an earlier instrument pool, providing unique insights into seismic activity and ocean basins.
Researchers have introduced a new method for making desalination membranes, allowing for greater control over thickness and texture. The electrospray technique produces films as thin as four nanometers with improved surface roughness, leading to better desalinization performance.
Tropical Storm Bebinca has cloud top temperatures as cold as minus 80 degrees Fahrenheit, producing heavy rainfall. The Joint Typhoon Warning Center forecasts a landfall just south of Hanoi late on Aug. 16 or early on Aug. 17.
A new study published in The Lancet Public Health journal found that moderate carbohydrate intake is associated with the lowest risk of mortality. Diets low in carbohydrates and high in protein and fats from animal sources were linked to a higher risk of death, while those with moderate carbohydrate intake had the longest lifespan.
Terence M. Keane, a BU School of Medicine professor, received the Presidential Award from the American Psychological Association for his outstanding work in trauma psychology and post-traumatic stress disorder research. He is a national leader in the field and has published over 300 articles on assessment and treatment.
Researchers at UNC School of Medicine discovered a rare gene mutation causing hydrops fetalis, a fatal condition in fetuses. The mutation impairs CLR receptor interaction with RAMP protein, disrupting adrenomedullin signaling and leading to fatal consequences.
The American College of Cardiology and the American Heart Association released an updated guideline for managing adult congenital heart disease (ACHD) patients, incorporating new data and growing expertise. The guideline presents a new classification system that captures complexity in both anatomy and physiology.
Tropical Storm Soulik is intensifying due to cold cloud top temperatures, potentially threatening Japan. The storm has maximum sustained winds near 63.2 mph and is forecast to move north then turn to the northwest.
The 3.4 billion year old Strelley Pool microfossils had chemical characteristics similar to modern bacteria, supporting a biological origin and ranking them amongst the world's oldest microfossils. The analysis also shows that these ancient fossils have survived extreme conditions over the last 3.4 billion years.
The complete wheat genome is now sequenced, enabling researchers to identify genes controlling traits such as drought resistance and breed plants with higher nutritional quality. This breakthrough accelerates innovation in breeding resilient and disease-resistant crops to meet global demand for wheat.
The study reveals that the rootworm uses specific iron complexes formed at the root surface when benzoxazinoids bind to iron to guide itself to nutrient-rich crown roots. This allows the insect to severely damage maize plants and undermine plant breeders' efforts to control it.
Researchers found that men and women show surprising differences in perceiving motion, with men picking up on visual motion faster than women. The study suggests that the difference may be due to disrupted processes in the brain that down-regulate neural activity in males.
A study found that eating white button mushrooms can alter the gut microbiome, producing short-chain fatty acids that regulate glucose production in the liver. This research holds promise for developing new diabetes treatments and prevention strategies.
The ShareBackup system uses fast switches and software to take over network traffic after a failure, minimizing downtime for applications. It can analyze problems, including misconfigurations, and diagnose faulty devices, helping data centers optimize their networks.
A new study reveals 6.5% of people over 40 experience phantom odors, unrelated to odor identification skills. Risk factors include age, sex, education level, and socio-economic status.
Researchers discovered CPEB4, a molecule regulating protein synthesis, is impaired in most autism cases. The study found defects in CPEB4 lead to dysregulation of hundreds of genes associated with autism.
A study by Anna-Lisa Vollmer and colleagues found that children give into social pressure from humanoid robots, unlike adults. The research used a conformity experiment with Nao robots and investigated the impact on children's decision-making.
Researchers from Binghamton University have developed a new manufacturing technique that can avoid the coffee ring effect in printing technology, resulting in improved inkjet printer quality. The technique uses electrospray to add nanoparticles to droplets, leading to more even dispersal of ink and stopping the coffee ring effect.
Researchers develop technique SCAR-seq to study epigenetic cellular memory transmission and find key protein MCM2. They discovered a controlled process in DNA replication ensuring symmetry between two new DNA strands.
Researchers at Kaiser Permanente are conducting a three-year study to examine the role of opioid use in suicide risk and develop better tools for clinicians. The study aims to improve powerful prediction models that can identify patients at high risk for suicide.
Researchers at the University of Copenhagen have developed a new method to diagnose cancer at its early stages using a malaria protein. The method retrieves individual cancer cells from blood samples, catching them in greater numbers than existing methods, allowing for earlier detection and improved treatment outcomes.
Researchers have developed a new technique using 'quantum chaos' to prevent optical filaments from forming in semiconductor lasers, leading to instabilities. The new system uses a D-shaped cavity to create a quantum chaotic landscape, disrupting the formation of self-organized structures and maintaining laser stability.
Researchers created an antilaser for nonlinear Bose-Einstein condensate of ultracold atoms, demonstrating perfect absorption without reflection. The breakthrough can be used to manipulate superfluid flows and study nonlinear optical systems.
A novel finger-prick test is 100% sensitive and specific for detecting Toxoplasma gondii infection during pregnancy. The test can rapidly inform obstetricians about the need for prompt treatment, potentially saving lives and preventing severe brain damage.
Weiwei Zhang, a UC Riverside psychologist, has received a five-year, $1.4 million grant to investigate how the brain supports encoding, maintaining, and accessing precise short-term and long-term memories.
Researchers used a super-resolution microscope to observe viral assembly, finding that envelope proteins are randomly scattered on the cell membrane rather than recruited by matrix proteins. This discovery could lead to more effective vaccines for enveloped viruses like influenza and HIV.
A large behavioral study shows a correlation between higher social dominance and faster decision-making in non-competitive situations. EEG measurements also reveal distinct neural signals for promptness in high-dominance men compared to low-dominance individuals.
Kansas State University scientists have cracked the wheat code, unlocking a detailed description of the bread wheat genome. The high-quality reference genome sequence will help produce wheat varieties with higher yields, enhanced nutritional quality, and improved sustainability to meet future demands of a growing global population.
Researchers at RIT will use photonic integrated circuit technology to improve processing speed and energy consumption of brain-inspired computing techniques. The project aims to realize high performance neural networks using light, enabling applications in autonomous systems, imaging, and cybersecurity.
The University of Oklahoma Health Sciences Center has renewed a $20 million federal grant to further research and patient care in Oklahoma. The program, Oklahoma Shared Clinical and Translational Resources, aims to improve health outcomes by conducting clinical and translational research with patients, particularly in rural areas.
Researchers have identified a new role for inhibition in regulating motor learning in the cerebellum, finding that inhibitory cell class molecular layer interneurons play a key role in modulating plasticity and learning behavior. This discovery provides fundamental insights into neural computation and mechanisms underlying motor learning.
Scientists have produced the most comprehensive map of a wheat genome, paving the way for more resilient and nutritious varieties. The detailed findings describe over 94% of the Chinese Spring wheat genome, with benefits expected to boost wheat improvement over the next decades.
Researchers found that high-fat diets suppressed a protein called TIGAR, which plays a role in meiotic spindle formation and antioxidant production. This led to increased reactive oxygen species and autophagy in oocytes, impairing development.
Researchers design a functionally graded material to minimize the tradeoff between flexibility and strength, achieving optimal balance in both elasticity and rigidity. This technology has wide applications in various fields, including engineering, medicine, and soft robotics.
A new study found an association between maternal pesticide levels and autism in children, with elevated DDE levels increasing the risk of autism by twofold. The study suggests a potential biomarker-based link between maternal exposure to insecticides and autism among offspring.
A study from Columbia University neuroscientists found that the human brain employs precise logic to decision-making, allowing prior knowledge to be updated based on new evidence. Participants learned to recognize and incorporate bias in a statistically optimal manner without confirmation bias.
A University of Montana researcher found that trees surviving a recent outbreak of mountain pine beetles had a distinct genetic makeup, differing from the susceptible population. This discovery suggests that resistance to the beetles may be heritable and provides hope for managing forest adaptation.
Researchers have developed a mouse model that induces scarring and damage similar to human idiopathic pulmonary fibrosis, allowing for the study of new pathways and targets. The model enables the testing of drugs in more clinically relevant ways, potentially leading to more effective therapeutic options.
The international team of researchers presents the first high-quality fully annotated reference genome sequence of bread wheat variety Chinese Spring. This advancement provides a powerful tool for accelerating the development of new wheat varieties designed to address human nutrition and crop resiliency needs.
The discovery reveals hundreds of individual galaxies in the cluster, which surrounds an extremely active supermassive black hole at the center. The quasar's light has obscured these galaxies, making them invisible to astronomers.
A team in Japan developed a new technique to detect and analyze biomolecules with inhomogeneous charge distributions by adjusting the solution. They achieved improved sensor response, allowing researchers to determine the Debye length and map out a molecule's uneven charge distributions.
Researchers have identified a protein complex that helps plants 'switch off' photosynthesis at night and 'switch on' when light is available again. This complex, involving thioredoxin-like2 (TrxL2)/2-Cys peroxiredoxin (2CP), allows plants to conserve energy and restore photosynthetic activity when necessary.
A new study published in Biological Psychiatry found that high maternal cortisol levels during pregnancy are associated with anxious and depressive-like behaviors in female offspring at the age of 2. The effect is linked to altered brain connectivity, particularly in the amygdala region important for emotion processing.
Researchers found that statins can improve conditions in people with autoimmune pulmonary alveolar proteinosis, a rare syndrome affecting 1 in 150,000 people worldwide. The study also identified two new tests to help diagnose the condition and showed promise for oral statin therapy as a potential new approach.
Researchers have developed printable metal tags that reflect WiFi signals, turning everyday objects into 'smart' Internet of Things devices. These tags can be attached to various objects and track user interactions, such as water bottle hydration levels or motor activity after a stroke.
New research reveals that female mosquitoes rapidly evolve more selective mating behavior when faced with existential threats from other invasive mosquito species. This adaptation is driven by genetic changes in specific gene regions and enables them to avoid sterility caused by interbreeding with male males of a different species.
Researchers at the University of Connecticut developed a new method to produce reverse osmosis membranes with controlled thickness and roughness, leading to improved efficiency and reduced fouling. The ultra-thin membranes exhibit high salt rejection and robust performance under various operating conditions.
A study found that individuals shot by police have arrest histories similar to those involved in assaults and homicides, and medical histories similar to those with self-inflicted firearm injuries. The study identified patterns among intent-specific firearm injuries, including increased risk of interpersonal and self-directed violence,...
A new study has evaluated the quality of YouTube videos for facial plastics information, revealing they can present biased information and offer an unbalanced assessment of risks and benefits. The study suggests these videos may not provide clear guidance on the qualifications of featured practitioners.
A study by researchers at the Instituto Gulbenkian de Ciencia found that the Spindle Assembly Checkpoint, a mechanism that regulates cell division, can sometimes be counterproductive. This checkpoint can increase genetic errors when cells have irreparable problems with chromosome cohesion.
Researchers discovered that only small clusters of four silver atoms in a tetrahedral shape surrounded by water molecules emit light. This is due to the movement of two free electrons, which decay from higher to lower energy levels and produce a specific shade of green light.
Marialis Rosario-Franco, a UTA doctoral student, has been awarded the Gröte Reber Doctoral Fellowship to study exomoons in four-body systems and their potential detection by modern radio telescopes. The fellowship allows her to conduct observational research at the NRAO's Very Large Array and Long Wavelength Array.
A study by Uppsala University found that sperm quality varies depending on a male's characteristics, such as attractiveness and age. For less dominant males, longer sperm is beneficial for fertilization success, while more attractive males benefit from smaller sperm.
A UTA professor led a federal advisory group to publish recommendations for preventing acute and chronic pain, highlighting the need for better public education and a precision medicine approach. The report found that psychosocial factors significantly impact pain experience and treatment responses.
A nine-month resistance training intervention improved exercise motivation and planning in older adults, with nearly half continuing independently. Participants who increased intrinsic motivation and confidence maintained twice-a-week training
Research led by Salk Institute scientist Gerald Shadel found that short-term stress can trigger sustained production of antioxidants and increase mitochondria efficiency, potentially extending lifespan. Cells exposed to brief stress showed higher antioxidant levels, more mitochondria, and less superoxide buildup than unstressed cells.