Researchers found microscopic neuropathology and neurophysiological changes in a rat model of mild traumatic brain injury. The study suggests that even mild exposure to a single blast shock wave can induce pathogenic effects that accumulate over time.
A high-resolution land surface model improves streamflow and soil moisture simulations over the Sanjiangyuan region. Natural climate change dominates changes in terrestrial hydrology, while anthropogenic climate change mainly affects ground temperature.
Researchers replace essential magnesium ions in the translational system with iron and manganese, revealing its robustness under primordial conditions. The experiment's success corroborates the translational system's place at the earliest foundations of life on Earth.
A NUS study found that mangroves can capture more carbon than tropical rainforests, making them a key solution to reduce fossil fuel emissions. Coastal ecosystems like mangroves can store organic carbon in water-saturated soil, effectively mitigating climate change.
Researchers found significant differences between bacterial and eukaryotic Hsp70s, including variations in binding interfaces and cycles of domain docking and undocking. These findings suggest that eukaryotic Hsp70s have evolved to be more flexible and efficient in their function.
A recent study published in PLOS ONE provides the most comprehensive analysis of a Hadrosaur bone bed in Europe, shedding light on the lives of these ancient herbivores. The research reveals that young individuals were more abundant than adults, suggesting a natural population dynamic.
The study reveals that online labor platforms provide companies with a simple and cheap mechanism to hire knowledge workers in lower-income countries. Workers from emerging economies can earn more and have more predictable work hours through these platforms, but their income can be less stable.
A team of scientists and engineers at the University of Illinois has developed a new technique for creating nanoscale-size electromechanical devices by using graphene as an etch stop. This allows for precise patterning of two-dimensional structures, enabling the creation of complex devices with improved performance.
Researchers found that the Wild Duck Cluster's stars are older than initially thought due to their rotational periods, which affect their hydrogen core mixing and lifetime. This discovery sheds light on how stars form and evolve, challenging previous assumptions about open clusters.
A multicity study found exposure to ground-level ozone and nitrogen oxides increases ED visits for respiratory and cardiovascular diseases. The study analyzed associations between cardiorespiratory ED visits and twelve major air pollutants across five US cities.
A new study by UMBC researchers highlights the importance of taking a long-term approach to reforestation efforts. Secondary forest patches are often quickly re-cleared, but their full benefits don't kick in until they're decades old. The study found that large patches and those alongside rivers were less likely to be re-cleared.
Researchers at the University of South Florida have developed a groundbreaking process that converts biogas from landfills into liquid diesel fuel, offering a sustainable alternative to traditional fossil fuels. This innovative method has the potential to reduce greenhouse gas emissions and increase energy independence.
Researchers at Lund University have made a groundbreaking discovery about bat flight techniques, revealing that they turn on the upstroke of their wings to navigate. This new understanding has significant implications for the development of next-generation drones.
A Columbia-led team has been awarded $16.75 million from the BRAIN Initiative to study the primary visual cortex, a region crucial for making sense of visual information. The five-year project aims to bridge the gap in knowledge between theoretical and experimental neuroscience.
A 9,000-year-old child's tooth has revealed insights into Alaska's ancient people, their genetic makeup and diets. The tooth, linked to the Ancient Beringian lineage, indicates that these groups remained in Alaska for thousands of years after migrating across the Bering Land Bridge.
Current MPAs in Finland protect only 27% of marine biodiversity, leaving many ecologically important species at risk. Increasing protected areas by just 1% can double conservation of the most important species.
Transitory populations in northern Ethiopia face increased risk of acquiring life-threatening VL infections. Research reveals obstacles to accurate diagnosis and treatment, including lack of diagnostic test kits and inconsistent use of protective measures.
A study by the Family Acceptance Project found that LGBT young people experiencing conversion therapy report higher levels of depression, suicidal behavior, and lower self-esteem. Parents serve as gatekeepers for both home-based and external conversion interventions.
Researchers at Martin Luther University Halle-Wittenberg develop a method to produce stable perovskite layers, which could lead to high-performance solar cells. The approach uses an industry-wide process to control layer growth, resulting in homogenous and controlled crystals that can withstand elevated temperatures.
A new study from the University of Eastern Finland found that flipped classroom teaching improved medical certificate writing skills compared to traditional lectures. The research involved 40 students from each group and showed a significant difference in scores, with flipped classroom students scoring better on average.
Tropical cyclone Alcide formed in the South Indian Ocean northeast of Madagascar, prompting NASA's Global Precipitation Measurement mission to analyze its rainfall. GPM's data revealed strong convective storms dropping rain at a rate of over 44 mm/hour, with measurements of precipitation heights made possible by DPR Ku Band radar.
Researchers identify significant impact of genetic diversity on peptide binding to HLA molecules, with implications for understanding HIV elite control and drug hypersensitivity. The study may also aid in the development of personalized vaccines.
Severe droughts in the Caribbean, exacerbated by climate change, threaten 2 million people's access to food and freshwater. The region has experienced a drying trend since 1950, with recent droughts pushing 1 million people into food shortages.
Two novel drugs have been found to restore normal behavior in rats lacking motivation by stimulating a build-up of dopamine in the synapses. This discovery holds promise for treating apathy and fatigue in humans, particularly those suffering from depression or caused by chronic diseases.
The project leverages the multiplexed VaxArray platform to deliver high-quality MR vaccines faster and at lower production costs. Measles and rubella vaccines can prevent these highly contagious diseases, which have had a significant impact globally.
A 30-year study found that warming waters caused rapid shifts in connected marine ecosystems, with smaller fish moving northward and entire communities inverting. The research suggests that future warming events could have major impacts on marine ecosystems and fisheries.
The Global Burden of Disease study estimates that global mortality rates stagnated in 2017, and half of countries face a healthcare workforce shortage. Only 41 out of 195 countries have more than 30 physicians per 10,000 population, highlighting the need for increased healthcare workers to achieve universal healthcare.
Researchers sequenced and compared the genomes of 332 yeast species, revealing an extensive picture of their evolution over hundreds of millions of years. The study suggests that yeasts evolved through reductive evolution, losing traits to specialize in specific food sources, with modern yeasts having narrower appetites.
A study published in Neuron demonstrates that neurons with the same projection target are more likely to connect with each other, despite being neighbors. This 'exclusion' principle of connectivity highlights a new rule of connectivity in the neocortex.
A new decision support tool, DIRECT CDS, has been developed to optimize post-acute care (PAC) referrals and improve patient outcomes. The algorithm helps clinicians identify patients most in need of PAC and suggests the level of care required.
A new method for treating and preventing acute kidney injury (AKI) has been developed using tiny, self-assembling forms of DNA origami nanostructures. These nanostructures were shown to protect the kidneys from harm as effectively as the leading drug therapy and alleviate symptoms of AKI.
The Amazon forest is failing to keep up with the effects of climate change, with more drought-resistant tree species outcompeting vulnerable ones. As a result, biodiversity is at risk, and existing intact rainforests need to be protected from deforestation.
Researchers and students from UCLA monitor seafood purchases from Los Angeles restaurants, extracting DNA to distinguish between fish species. They find that sushi mislabeling is pervasive, but intentional fraud is less common, with some restaurants already implementing changes based on their findings.
Researchers at CRAG have successfully generated plants with enhanced drought resistance by modifying steroid hormone signaling, a major breakthrough in agriculture. These drought-resistant plants exhibit improved water-stress tolerance without compromising growth.
A CWRU-led study shows a single dose of the new triple-drug therapy is significantly more effective at killing microscopic larval worms in people diagnosed with lymphatic filariasis. This finding has led to changes in WHO treatment guidelines, offering promise for eliminating this disease from global health threats.
Studies in mice with psoriasis-like conditions found that stiff blood vessel walls trapped cholesterol, promoting plaques and increasing cardiovascular risk. Neutralizing a specific immune cell type reduced collagen density and cholesterol deposits, suggesting a preventable link between autoimmune diseases and heart disease.
Spikeling, a low-cost DIY kit, simulates how nerve cells in the brain compute information, allowing for hands-on learning of neuroscience. The kit's open design and free availability aim to level the playing field in global science education, making complex concepts accessible to students worldwide.
Research suggests that all infectious diseases follow a seasonal cycle, with outbreaks occurring at specific times of the year. Seasonality is driven by environmental factors such as temperature, humidity, and vector-borne diseases like Zika, which is influenced by mosquito proliferation in algae-filled waterbodies.
Researchers found that mutations in specific genes also attack sensory neurons, leading to new insights for preventing or reversing ALS. Sensory neurons' axons exhibit similar pathological changes as motor neurons, making them a potential target for discovering and testing molecules to treat ALS.
A new study finds Transarterial Radioembolization with Yttrium-90 (TARE-Y90) effective and feasible in children with difficult-to-treat liver cancer. The treatment offers a less toxic alternative for patients who have not responded to chemotherapy.
Researchers at Stanford University have created a device that can collect heat from the sun and coldness from outer space at the same time. The technology combines radiative cooling with solar absorption, allowing for simultaneous heating and cooling, which could improve solar cell efficiency.
Researchers found orangutans spontaneously manufactured hook tools out of straight wire, solving a complex problem that eludes young human children. The apes' innovation abilities were tested using a hook-bending task, where they successfully bent and unbent wires to retrieve rewards.
A team of researchers at Osaka University has identified the molecular mechanism that enables cells to move in a specific direction. By analyzing the interaction between PTEN and PIP3 molecules, they found that these molecules mutually suppress each other, preventing cells from forming pseudopodia at different ends.
Scientists have discovered that some retina cells may be using an ancient light-sensing mechanism, which suggests a possible connection to the earliest photoreceptors. This finding was made in mice and has implications for understanding vision and its relationship to other biological processes.
A team of evolutionary biologists reconstructed the genomic and metabolic characteristics of a 400-million-year-old common ancestor of more than 1,000 budding yeast species. This ancestor was metabolically diverse, able to live on a third more food sources than modern counterparts.
Researchers create an algorithm that accurately classifies mouse vigilance states into wake, REM sleep, and non-REM sleep based on local brain activity in the olfactory bulb. The study has potential applications in medical and clinical fields, including surgical anesthesia and sleep disorders.
Scientists have identified a wild tea plant in China that contains virtually no caffeine and may provide the health benefits of regular brewed teas. The newly discovered plant, known as hongyacha, was found to contain several potentially health-promoting compounds not found in regular tea.
Researchers discovered a self-protection mechanism in failing heart cells that triggers the regulation of genes promoting heart failure. The study reveals that one fragment of the protein junctophilin-2 protects against damage by traveling to the cell nuclei.
Researchers found that pro-leave and remain supporters were clustered around areas with similar voting patterns, contradicting the assumption that echo chambers are solely online phenomena. The study analyzed 33,889 Twitter posts from the Brexit referendum campaign period.
Researchers discovered that people burn 10% more calories at rest in the late afternoon and early evening compared to the early morning hours. This finding highlights the importance of the circadian clock in regulating metabolism.
Research reveals epigenetic changes in IGFBP2 gene influence type 2 diabetes risk. Higher IGFBP2 levels in blood lower diabetes risk.
The Center for Advancing Point-of-Care Technologies (CAPCaT) will assist inventors developing innovative point-of-care devices and technologies for patients with heart, lung, blood, and sleep disorders. The center aims to reduce in-patient hospital stays and improve quality of life.
Scientists demonstrate that epigenetic variation in plants can be selected for and passed on through generations, enabling quick adaptation to environmental changes. This discovery opens new opportunities for crop breeding and could help plants thrive in a changing climate.
Researchers have discovered that metastatic cancer cells follow a Lévy walk movement pattern, like sharks searching for food, which aids in their rapid spread and direction. The team was able to reprogram this behavior using chemical inhibitors, changing it back to more typical diffusive motion
A recent study published in Academic Emergency Medicine demonstrated that long-term follow-up in a trauma patient population is feasible. The study used established contact strategies and various interview locations to track hard-to-reach populations. Researchers suggest exploring newer methods of contacting participants through techno...
A new antibiotic, zoliflodacin, has shown promising results in treating uncomplicated gonorrhea infections with a single oral dose. The study found a cure rate of 96% for participants treated with zoliflodacin, compared to 100% for those treated with ceftriaxone.
A new study from NTNU and Harvard University reveals that young men who strive for an unattainable muscular body are at risk of depression, weekend binge drinking, and disordered eating. The study also shows that over one-third of young men have been on a diet in the past year, unrelated to obesity.
A University of Pennsylvania study found that limiting time on Facebook, Snapchat, and Instagram leads to significant decreases in depression and loneliness. The researchers connected social media usage with decreased well-being through objective data tracking iPhone battery screens.
A recent study sequenced ancient genomes from Alaska to Patagonia, debunking a long-standing theory about Paleoamerican presence in North America. The research found the Spirit Cave remains were genetically closer to contemporary Native Americans than any other ancient or contemporary group.
Researchers found that the brain recognizes familiar faces more uniformly across the visual field through repeated social interactions. The study suggests that early visual processing is tuned for consistent recognition of personally familiar faces.