Researchers at USC Viterbi's Mork Family Department of Chemical Engineering and Materials Science have discovered a fatal vulnerability in many cancer cells: their inability to adapt to alternative sugars like galactose. The discovery could lead to new metabolic treatments for cancer, targeting cells with specific genetic mutations.
A new longitudinal study found that teenagers whose parents are overbearing experience difficulties in social relationships and educational attainment by adulthood. The study, published in Child Development, suggests that overcontrolling parenting can stunt adolescent development and lead to long-term problems.
A $26.9-million project aims to create rapidly acting, effective, and safe psychiatric medications by targeting G protein-coupled receptors. The research seeks to overcome the limitations of existing drugs with severe side effects.
Astronomers have detected a supermassive black hole's heartbeat, which has been ongoing for over ten years. The signal was spotted again in 2018 using X-ray satellite observations, providing valuable information about the black hole's event horizon.
A team of researchers has found direct evidence that massive coal burning in Siberia led to the Permo-Triassic Extinction, resulting in up to 96% marine species and 70% terrestrial vertebrate extinctions. The study suggests that catastrophic global warming devastated life on Earth.
The Ireland-based NPIC will provide enhanced research data for clinical trials aiming to improve patient outcomes in various diseases, including cancer, neurology, and psychiatry. The Centre's imaging infrastructure will be open to all researchers, supporting collaboration between academia, industry, and not-for-profit institutions.
Bacteria-based nanobiohybrids have the potential to provide a targeted and effective approach for cancer treatment. Nanobiohybrid systems combine bacteria with nanomaterials in cancer therapy, offering advantages such as tumor targeting ability, genetic modifiability, and multimodal therapy.
A review paper argues that bacteriophages are essential for maintaining healthy bacterial communities around plant roots, which is vital for plant growth. The researchers suggest that these phages can stimulate microbes to protect plants during droughts and transfer DNA between cells, leading to new functionalities.
Using regional anaesthesia instead of general anaesthesia for hip and knee replacement procedures can significantly reduce greenhouse gas emissions. By eliminating volatile halogenated agents, regional anaesthesia decreases atmospheric pollution, contributing to a potential solution to global warming.
Researchers found that brief exposure to endocrine-disrupting chemicals during liver development can prematurely age the epigenome, leading to accelerated aging and increased susceptibility to metabolic disorders. This study highlights the long-term effects of environmental exposures on health and disease susceptibility.
A joint research team from Hong Kong, Beijing, and Shanghai discovered a rare-earth magnet TmMgGaO4 (TMGO) that realizes the long-sought-after two-dimensional topological Kosterlitz-Thouless (KT) phase. The breakthrough provides the missing piece of KT phenomena in bulk magnetic materials.
This study evaluated the relationship between preoperative Geriatric Nutritional Risk Index and long-term outcomes in elderly gastric cancer patients. The results showed that the GNRI is a useful prognostic indicator for estimating overall survival, cancer-specific survival, and postoperative outcomes.
A Phase 2 study led by UB pediatric endocrinologist Teresa Quattrin shows that golimumab, an anti-TNF therapy, preserved beta-cell function and reduced injected insulin required in children and young adults with newly diagnosed Type 1 diabetes. The study demonstrated a higher C-peptide level in patients treated with golimumab compared ...
Researchers at the University of Michigan developed a system that measures occupants' facial temperature to determine optimal temperatures for comfort. The Human Embodied Autonomous Thermostat (HEAT) aims to reduce energy consumption and enhance indoor comfort.
Two NAU research centers, Pathogen and Microbiome Institute (PMI) and Center for Health Equity Research (CHER), received funding to support COVID-19 response efforts. PMI will test vaccine and treatment efficacy using its Biosafety Level 3 facilities, while CHER will model disease spread in rural areas.
A new study found that rehabilitated Kemp's ridley and loggerhead sea turtles exhibit a substantial stress response when transported to release locations in the southern United States. Despite this, the turtles remained physically stable and ready for release, with minimal impact on their vital signs or blood data.
A recent study from the University of Southampton found that caring responsibilities disproportionately affect older adults' mental and physical health. Nearly a fifth of men and over a quarter of women reported providing care, leading to increased risk of chronic diseases and decreased productivity.
A computer science researcher has developed an algorithm called Orchestra that reduces spikes in resource demands in cloud computing, allowing companies to maintain smooth operations despite increased work-from-home usage. The solution uses lightweight monitoring and performance-based models to adjust cloud resources in real-time.
Researchers from Kumamoto University identified a plant gene that balances growth with defense mechanisms to protect against nematode infections. The DEL1 gene helps plants allocate energy to growth rather than defense, leading to increased yields and resistance to pests.
A new study published in the Journal of Nutrition found that consuming lean beef as part of a healthy diet does not negatively impact cardiovascular health or type 2 diabetes risk. The study compared two diets: one with an additional 5.3 ounces of lean beef and another without it, both following US-style eating patterns.
Researchers synthesized BP-structured nitrogen using diamond anvil cell apparatus and high-power laser heating. The new material exhibits colossal Raman intensity and unusual optical properties.
A new multi-institutional study found patterns of abnormal brain MRI findings in patients with severe COVID-19, including signal abnormalities in the medial temporal lobe and non-confluent multifocal white matter hyperintense lesions. The study suggests that imaging and neurological follow-up are crucial to evaluate prognosis.
Researchers found that male guinea pigs' hormone systems adjust after being transferred from colony housing to pair housing with an unfamiliar female. This adaptation allows them to exhibit more aggressive behavior in defense of the partner, similar to those in prior pair-housing conditions.
Two new tanaid species were discovered by NUS researchers in the eastern Pacific Ocean, providing insights into biodiversity in the Clarion-Clipperton Zone. The discovery is significant for environmental management, as it sheds light on the ecosystems and potential resource areas of this understudied region.
Annals of Internal Medicine publishes new COVID-19 research, highlighting the importance of high-quality clinical trials and informative multi-group trials to counteract misleading information. The journal also emphasizes the potential for the pandemic to transform medical care, education, and work.
Experts demand a prominent target of 20 species extinctions per year to lower biodiversity loss rates and protect ecosystem services. The proposed target is comparable to the 2-degree climate target, which aims to reduce greenhouse gas emissions and mitigate climate change.
The research team developed a new MTJ stack design technology and highly reliable fabrication technology for Quad interface type iPMA-MTJ. Quad-MTJ achieved a 20% reduction in write density at a 10ns high speed write operation, maintaining data retention for over 10 years and higher operating temperatures than Double-MTJ.
Research uncovering a new mechanism causing colorectal cancer found that abnormal Zeb2 expression undermines the integrity of the intestinal wall, allowing infiltrating bacteria to cause inflammation. Removing the microbiota or modulating the immune system can prevent cancer development.
Researchers developed a new method, HT-DBP, to screen thousands of drugs in freshly collected human tumor cells, potentially leading to more accurate and personalized treatment. The technique indicates which drugs are most likely to be effective against specific cancers, improving physicians' ability to tailor treatment.
A new species of diamond frog, Rhombophryne ellae, has been discovered in Montagne d'Ambre National Park, northern Madagascar. The species features distinctive orange flash-markings on its legs and large black spots on its hip. Its discovery highlights the gaps in knowledge of amphibians in tropical regions.
The BioRescue consortium successfully extracted oocytes from a southern white rhino female and created four viable embryos through advanced assisted reproduction technologies. This breakthrough procedure has nourished hope for the survival of the northern white rhino species in the near future.
A new study found that ability-based classes severely affect pupils' self-confidence, particularly in maths. The research suggests that students in top sets have higher self-confidence in maths and English, while those in bottom sets have lower self-confidence, widening the gap over time.
A randomized clinical trial investigated treating patients with relapsing multiple sclerosis using a therapeutic hookworm infection, comparing it to placebo. The study aimed to determine if gut worms could induce immune responses that protect against multiple sclerosis.
A recent study found that seven patient samples contained M. orygis, a subspecies not typically associated with human TB, indicating potential zoonotic transmission in India. The researchers suggest broadening the definition of zoonotic TB to include other MTBC subspecies capable of causing human disease.
A recent survey by the CUNY Graduate School of Public Health found that one in four households with children under 18 have reported a child experiencing hunger, leading to weight loss and health concerns. The survey also highlights widening dietary inequities among low-income and minority households.
Researchers analyzed insurance claims from 2016 to 2019 and found that out-of-pocket costs for respiratory illnesses were particularly high for consumer-directed plans. Tens of millions of Americans with self-insured health plans may face significant financial burden due to COVID-19 hospitalizations.
Researchers analyzed data from three large study groups with up to 32 years of follow-up to investigate the link between healthy eating patterns and cardiovascular disease risk. The study found that long-term adherence to recommended diets was associated with a lower risk of heart disease and stroke.
Researchers at Scripps Research Institute isolate powerful coronavirus-neutralizing antibodies from recovered COVID-19 patients and test their effectiveness in animals, achieving results in under seven weeks. The discovery offers hope for a rapid response to the pandemic and potential clinical trials for treatment and preventive measures.
Researchers have created the first quantum phase battery, which induces supercurrents in a quantum circuit by providing a persistent phase difference. The battery consists of an indium arsenide nanowire and aluminum superconducting leads.
Several newly discovered human antibodies target the SARS-CoV-2 virus, offering promising therapeutic leads and potential protection against new coronavirus outbreaks. Researchers have isolated hundreds of antibodies from convalescent donors, with some showing strong cross-neutralization capabilities against related bat coronaviruses.
A new model developed by Duke University engineers can accurately recreate the dynamics of historic and current landslides, pointing to the temperature of a thin layer of clay as critical to its potential for sudden cataclysmic failure. The approach is being used to monitor an evolving landslide in Andorra.
Scientists analyzed mineral data from glaciers to determine Earth's climate before the Neoproterozoic glaciation. They found that the planet may have experienced a gradual cool-off into a Snowball Earth state, rather than an abrupt transition.
McKone's project aims to convert carbon dioxide into useful fuels and chemicals, addressing the environmental impact of excess CO2. He is developing new catalysts and reactors to mimic biological enzymes and improve efficiency.
A study found that child access prevention (CAP) laws, but not right-to-carry (RTC) or stand your ground (SYG) laws, are associated with reduced firearm-related deaths. States with more restrictive policies had 11% fewer firearm deaths, corresponding to an estimated 4,475 fewer deaths per year.
Scientists have found that cell wall extracts from immune-active plants can trigger plant immunity and disease resistance, providing a new approach to protecting crops against pathogens and pests. This breakthrough discovery could lead to the development of simple, sustainable, and effective treatments to reduce crop losses.
The COVID-19 pandemic has exacerbated food insecurity and financial instability for low-income households, with many struggling to access affordable groceries and navigate online shopping systems.
Research examined childhood neighborhoods and adult education in Sweden from 1939 to 2015. The study found that social context of nearest neighbors during childhood predicted adult educational attainment, regardless of family background or school district.
Scientists at NIST and MIT developed a practical technique to control magnons, enabling efficient operation at room temperature. The new approach uses silicon substrates and has potential for industry-scale production, paving the way for highly efficient computer technology.
Researchers estimated life expectancy differences between HIV-infected and uninfected adults from 2000 to 2016. Antiretroviral therapy has increased life expectancy for those with HIV, addressing a gap in recent data on the topic.
Researchers have created a technology to print tissues directly in the body, using a specially-formulated bio-ink that can be crosslinked safely using visible light. This breakthrough enables minimally-invasive laparoscopic options for tissue repair and engineering, saving time and cost.
The Pew Scholars Program in Biomedical Sciences supports early-career researchers with four-year funding for foundational research. This year's class of 22 scholars tackles complex questions in biomedicine, including aging differences between males and females, inflammatory disease trajectories, and temperature regulation mechanisms.
A $3.3 million NIH grant will fund research into the structure and mechanisms of TDP-43, a protein linked to neurodegenerative conditions like ALS and Alzheimer's disease. The study aims to better understand how post-translational modifications affect TDP-43 assembly and interactions with therapeutic targets.
A study found that lower socioeconomic status accelerates decline in physical functions such as grip strength and gait speed, as well as cognitive abilities like memory and processing speed. Social circumstances also impact mental health, with less wealthy individuals experiencing more depressive symptoms and sight problems.
A new study found that UK ethnic minorities continue to face significant challenges in employment, with many groups more likely to be in manual work or unemployed than their white counterparts. The research highlights the impact of persistent racism on access to positive socioeconomic outcomes and social mobility.
Researchers discovered that vaccinated participants were less generous to non-vaccinated individuals than to other vaccinated peers, especially among those who viewed vaccination as a moral duty. This suggests that vaccination is perceived as a societal obligation, transcending social group affiliations.
A new study in The American Journal of Pathology reports that gene expression analysis of lung explant tissue can accurately differentiate pulmonary arterial hypertension (PAH) from pulmonary veno-occlusive disease (PVOD). This molecular approach promises to facilitate clinical diagnostics and develop novel target-specific intervention...
Researchers analyzed remains from a 30,000-year-old burial site in France, revealing sorted bones and elaborate cave art. The study provides new insights into complex mortuary dynamics of the Gravettian culture.
Researchers found surprisingly high growth rates for Leptoseris species at depths of up to 360 feet, with some colonies growing nearly 1 inch per year. This challenges the assumption that deep corals grow slowly due to low light levels.
A four-month rapid research project will investigate how public health measures are received and spread in Gaza's overcrowded refugee camps. The study seeks insight into the challenges of disseminating health information to communities with limited access to resources, aiming to improve communication strategies.
A new nonsurgical treatment decreases errant blood flow in the shoulder to quickly reduce pain and improve function in patients with adhesive capsulitis, also known as 'frozen shoulder'. The treatment was successfully completed in 16 patients whose symptoms had not responded to conservative treatment over 30 days.