The University of North Carolina at Chapel Hill has secured renewed funding for the Cancer Prevention and Control Research Network (CPCRN), a flagship program for preventing and controlling chronic diseases. Researchers from eight institutions will collaborate to produce research on implementing evidence-based approaches to reduce canc...
A genetic mutation in SRSF2 disrupts DNA's message sending process, leading to excessive NMD activity that destroys healthy blood cells. This excessive activity is a hallmark of blood cancer. Researchers discovered an effective treatment approach using antisense oligonucleotide therapy.
George Mason University Professor Linda Mason received a grant to develop and implement activities promoting inclusion in early childhood education. The project aims to build capacity of quality programs through partnerships with leaders in early childhood special education.
Intratumoral SD-101 injection complements low-dose cyclophosphamide in boosting innate immunity and driving potent T cell-mediated anti-tumor responses. This combination therapy improves efficacy against non-injected tumors and long-term survival, even in large tumors.
A recent study published in Biological Reviews found no conclusive link between wild birds and human illness involving E. coli, Salmonella, and Campylobacter. The researchers highlighted the need for more definitive research to determine the risks of bird populations on food safety before taking action.
Researchers create a novel, flame-retardant electrolyte for potassium and potassium-ion batteries, enabling safe operation at reduced concentrations. The new electrolyte allows for stable cycling of batteries with concentrations suitable for large-scale applications.
A study published in Frontiers in Veterinary Science found that a program combining horseback riding and cognitive training improved motor skills, behavior, and academic performance in children with neurodevelopmental disorders. The program showed promise for improving the lives of young people with ADHD and autism spectrum disorder.
Researchers found a significant spike in new colorectal cancer diagnoses between ages 49 and 50, indicating many latent cases were likely going undiagnosed until screening began. The majority of these cases (93%) were invasive, requiring aggressive treatment, including surgery.
The Society for Developmental and Behavior Pediatrics Clinical Practice Guideline provides a framework for diagnosing and treating complex ADHD in youths. The guideline aims to improve systematic approach to diagnosis and treatment for children with persistent ADHD symptoms.
Researchers developed a Noncontact Catalysis System (NCCS) to accelerate chemical reactions using gold nanoclusters as intermediaries, enabling independent reactions of normally incompatible substances. This breakthrough could lead to more versatile, efficient, and cost-effective industrial chemical production processes.
Researchers at Yale School of Public Health have identified a new family of surface proteins, Fam10, which are uniquely associated with infectious metacyclic parasites transmitted by the tsetse fly. Vaccination with one member of this family significantly reduced parasitemia in mice, making Fam10 proteins promising vaccine candidates.
Researchers found that Dirac semimetals exhibit robust, conducting electronic states in 1D, challenging previous conclusions about the nature of these materials. The discovery settles the decades-old problem of whether condensed matter Dirac fermions have topologically protected surface states.
Physicists propose using ultra-high energy neutrinos to study interactions beyond the standard model, with a new resonance dubbed the 'Zee burst.' This detection could reveal exotic particles such as supersymmetric partners and heavy decaying dark matter.
Researchers found CNVs to be genomic modifiers of ASD/DD risk in individuals with PHTS, providing insight into the disorder's clinical outcomes and potential predictors for medical management. The study suggests CNV burden analysis may aid in predicting clinical outcomes for other clinically heterogeneous disorders.
Researchers found similarities between the novel Wuhan coronavirus's receptors and those of SARS-CoV, a key finding in understanding its ability to infect humans. The study suggests that mutations in the virus could enhance its binding to human ACE2, leading to increased transmission.
Researchers from Yale School of Forestry & Environmental Studies argue that the IPCC guidelines need improvement to accurately calculate and report greenhouse gas emissions. They suggest using satellite imagery and machine-learning tools to expedite quantitative synthesis and address data gaps.
Patients living with HIV who attend religious services regularly experience higher emotional and physical well-being, while privately religious individuals face mental health challenges. Researchers suggest integrating spiritual beliefs into holistic treatment programs to improve health outcomes.
A new Ohio law allowing pharmacists to dispense naloxone without a prescription has been linked to an increase in naloxone dispensing rates. The study found that the law resulted in more naloxone being made available to patients, potentially saving lives in opioid overdose situations.
Researchers at McGill University have launched interactive story maps to highlight the importance of wetlands, which support a disproportionately high number of endangered species. Wetlands also naturally combat climate change by storing carbon dioxide underground.
Researchers at Louisiana State University have developed a new cationic cobalt bisphosphine hydroformylation catalyst system that is highly active and extremely robust. The discovery has the potential to replace rhodium-based catalysts, which are currently expensive and in short supply.
A comprehensive study of congenital heart disease found lower predicted long-term survival, higher remission rates, and lower prevalence in low-income countries compared to high-income nations. The study revealed a significant disparity in CHD mortality rates between countries, with most deaths occurring in infants under one year old.
A new study published in Nature Communications found that sevoflurane anesthesia leads to more metastatic burden in the lung after breast tumor resecting surgery than propofol. The findings may guide clinicians in optimizing anesthesia choice for breast cancer surgery to achieve best long-term outcomes.
Dr Johann Rafelski reviews decades of work on quark-gluon plasma, exploring strangeness production and discovery methods. He highlights the evolution of understanding this primordial material, which once filled the Universe, and the ongoing experimental efforts to recreate it.
Researchers found that smelling roses before and after bedtime can improve English vocabulary learning by 30%. The study suggests a practical application of fragrances to enhance learning during sleep.
A Far Eastern Federal University scientist is working on a new photopolymer silicone that can be quickly cured through UV radiation, enabling complex configurations. The compound aims to overcome the challenges of current silicone printing technology, which is currently unsuitable for producing detailed parts.
Researchers from Trinity College Dublin used supercomputers to simulate quantum systems and found a deep link between entanglement and thermalisation. The study provides new insights into the fundamental process of thermalisation and its relationship with quantum mechanics.
Researchers developed a novel anti-CEACAM antibody for fluorescence visualization of colorectal tumors and metastases. The antibody targets multiple CEACAMs, which can lead to improved detection of tumor margins and metastases with variable expression of CEA.
A special issue of Young explores how young people use music to express their feelings on the crisis, with studies focusing on feminist reggaeton in Spain and rap/mahragan in Egypt. The research shows how these genres have become politicized tools for subversive empowerment and resilience.
A study suggests that combining NKTR-214 with adoptive cell therapy may produce a stronger immune response against advanced melanoma, increasing the number of anti-tumor immune cells and their lifespan. This approach could be effective for more patients with advanced solid tumors.
Researchers developed a new database of gene essentiality, providing insight into the causes of rare childhood diseases. The study identifies new mutations likely responsible for these conditions and offers a valuable resource for clinicians and researchers.
According to a new study, human activities have inadvertently increased plant growth globally, which absorbs carbon dioxide and cools the planet. This 'global greening' trend could be slowing down global warming by up to 0.2-0.25 degrees Celsius.
Researchers at Monash University developed a wearable device using continuous wave radar and photoplethysmogram sensors to calculate continuous blood pressure measurements. The device achieved high accuracy rates, with 93% success during sedentary tasks and 83% during exercises.
The technique reduces waiting time for compatibility testing, improving transplant surgery scheduling and alleviating patient stress. Virtual crossmatching resulted in a 2.4-hour decrease in cold ischemia time and a 26% decline in delayed graft function.
Pre-clinical studies reveal that cortical spreading depression and calcitonin gene-related peptide (CGRP) play significant roles in migraine. Botox, CGRP, and PACAP-38 show promise as potential treatments.
Researchers have discovered that the glymphatic system goes awry during a stroke, promoting brain cell drowning and swelling. This finding may lead to novel interventions to reduce stroke severity and improve outcomes.
The study reveals an intricate universe of nanoscale rods, sheets and spirals that form spontaneously in eutectic solidification. This discovery could lead to the creation of lightweight alloys and optical products with superior properties.
A new modelling study estimates that up to 75,800 individuals in Wuhan may have been infected with 2019-nCoV by January 25, 2020. The researchers also suggest that multiple major Chinese cities might have already imported dozens of cases of 2019-nCoV infection from Wuhan.
Researchers at George Mason University will investigate the role of early life exposures in childhood health and disease as part of a $1.5M NIH grant. The project aims to understand how early life experiences impact children's development and health outcomes.
The University of Texas Health Science Center at Houston has received a $3 million grant to provide child development strategies to infant and toddler specialists and teachers. The training focuses on improving interactions between teachers and children, as well as family engagement strategies to build strong emotional and social skill...
A new cryopreservation technique has been developed to preserve genetically modified rat spermatozoa, which are difficult to store due to their large size and sensitivity to temperature changes. The method, tested on genetically modified rats, successfully produced over 300 offspring from a single male rat.
Researchers analyzed DNA data from African American and Caucasian American men with prostate cancer, finding lower frequencies of pathogenic/likely alterations in 14 well-characterized DNA repair genes among African Americans. The study suggests a higher risk for germline BRCA mutations but lower risks for non-BRCA mutations
Researchers at Boston University School of Medicine have identified the unique genetic program behind primordial lung progenitors, a rare and transient cell type. This discovery may lead to improved stem cell protocols for treating respiratory diseases such as COPD, cystic fibrosis, and lung interstitial disease.
A recent study using national data from over 895,000 US adults examined the association between state regulations and e-cigarette use. The results show that stricter state regulations are linked to lower adult e-cigarette use.
A four-year project examined how schools use screening tools and factors influencing their use. The study found that school leader knowledge and attitudes are key to proactive screening approaches, leading to better outcomes for students.
Researchers identified novel PMEPA1-e isoform and characterized its biological functions in prostate cancer. The study found that the methylation of PMEPA1 gene promoter accounts for silencing of PMEPA1 in prostate cancer cells.
Disturbances in the internal clocks of pancreatic cells are linked to type-2 diabetes. Researchers successfully restored clock function using a natural compound, improving insulin secretion and providing new hope for diabetes care. The study shows that synchronizing the internal clocks can help regulate blood sugar levels.
A team of doctors and engineers developed a noninvasive device that measures brain metabolism using an infrared laser, enabling faster and more certain concussion diagnoses. The technology could guide treatment for serious brain injuries and other conditions, improving patient outcomes.
Researchers at Washington State University and UMass Amherst will explore the role of bacterial fragments in regulating sleep and circadian rhythms. They aim to determine how these fragments affect brain functions, including sleep, cognition, mood, and appetite.
Gary M. Shaw, DrPH, receives the SPR's Douglas K. Richardson Award for his significant contributions to child health research. He has made substantial contributions to understanding genetic and environmental risk factors for human birth defects.
The updated atlas provides detailed profiles for 14 shark species, including bull and tiger sharks, and significantly extends their known ranges and movements. The data collected through the Cooperative Shark Tagging Program has filled in gaps in the geographic distributions and movements of most shark species.
A novel HIV antibody, 1-18, has been identified as a highly potent and effective treatment option. Unlike other antibodies, it prevents the development of viral resistance, maintaining suppressed viral loads for extended periods.
A new 10-week program called GripTape aims to help young people find their way in life. Researchers will examine its effectiveness and underlying mechanisms to clarify why it works for whom.
A team of scientists led by Prof. Dr. Christian Schachtrup found that fibrinogen inhibits the neuronal differentiation of NSPCs, leading to increased astrocyte formation and reduced scars. By reducing fibrinogen levels, they were able to block astrocyte formation from NSPCs.
Melodie French has earned a prestigious National Science Foundation CAREER Award to support her research on the physics responsible for earthquakes. The grant will enable her lab to study rocks exhumed from subduction zones, characterizing the strength of rocks deep underground where plates meet.
Low birth weight is linked to poor cardiorespiratory fitness in young adults. The study found that babies born at term weighing more than average had better fitness levels, with a 7.9-watt increase for every 450 grams of extra weight.
Researchers extracted DNA from museum specimens using a vortex fluidic device (VFD), accelerating the process from days to hours. The breakthrough enables exploration of historical and extinct species' genetic information, shedding light on human impact on ecosystems.
The Damon Runyon Cancer Research Foundation has awarded $231,000 in funding to 16 postdoctoral scientists conducting innovative cancer research projects. The Fellowship aims to encourage promising young scientists to pursue careers in cancer research.
A team from Universitat Rovira i Virgili developed an algorithm that makes accurate predictions and generates interpretable models. This allows for a better understanding of the data, reducing biases in original data and providing valuable information for scientists.
A study of Medicaid expansion enrollees in Michigan found a six-point increase in employment or student status in one year, with larger gains seen among African-Americans, men, and those with low incomes. The findings suggest that expanding Medicaid coverage can help achieve fuller employment among low-income residents.
Researchers analyzed ancient fats and lipids in pottery from the Amur River in Russia, dating back 16,000-12,000 years. The study reveals that separate groups developed similar technological solutions to process food during periods of major climatic fluctuation.