A new study found that hormonal changes during menopause lead to gastrointestinal problems such as indigestion, nausea, and bloating. The study suggests an association between race/ethnicity and menopause status with GI symptoms, with different racial/ethnic groups experiencing varying severities of symptoms.
The Liberty Asthma VOYAGE trial found that dupilumab significantly reduced the rate of severe exacerbations by nearly 60% and improved lung function and asthma control in children ages 6 to 11. Dupilumab was also shown to be safe, with minimal adverse reactions.
A new study by Orygen has shown that early psychosis programs delivered in Australian headspace centres significantly improved the clinical and functional outcomes of young people. At six months, both groups experienced considerable improvement in psychological distress and psychosis symptoms.
Scientists have developed a novel way to analyze nitrogen isotopes in whale baleen to reconstruct the animal's diet, trophic level, and migration pattern. The method reveals annual migration patterns between Arctic and North Atlantic oceans, providing insights into threatened population migration pathways.
A new method measures glomerular filtration rate using D-serine clearance, showing strong correlation with GFR and lower bias than creatinine clearance. This could improve clinical practice and reduce dialysis patients.
Researchers discovered that appealing to athletes' sense of 'future guilt' through psychological intervention was a more powerful initial reaction than education programmes highlighting the risks of doping. The study also found that receiving useful information about doping strengthened athletes' confidence to resist temptation.
A University of Otago study surveyed 529 students to investigate factors influencing the switch from illicit to lawful cannabis sources. The main facilitator identified was perceived safety, with 63% of respondents citing this as a primary reason for sourcing cannabis through legal channels.
The American Association for Anatomy (AAA) has funded the Portfolios of People: Advancing Anatomical Representation Together (POP AART) program. This project aims to create an accessible digital library of representative photographs and illustrations of diverse individuals, addressing a lack of inclusive visual supplements in anatomy e...
Researchers report that combining infection and vaccination produces high-quality antibodies effective against COVID-19 variants. The study found that prior-infected individuals who received a vaccine had potent antibodies against new variants, contrary to previous findings suggesting reduced potency.
Researchers found damage to a brain part that regulates hyperactivity contributes to both memory issues and seizures in the most common form of epilepsy. This discovery may lead to earlier diagnosis and new treatments for epilepsy and related disorders.
A randomized clinical trial investigated the effects of a Mediterranean diet and mindfulness-based stress reduction on preventing small-for-gestational age birth weights. The study found that these interventions significantly reduced the risk of this adverse pregnancy outcome.
A study published in Journal of Biological Rhythms found that antibody levels are higher when healthcare workers received the SARS-CoV-2 vaccine in the afternoon. The study suggests that circadian rhythms may play a role in regulating immune responses to COVID-19 vaccination.
Researchers found that urinary incontinence can distract from balance and stability, increasing the risk of falling in older adults. The study showed that the feeling of having to pee acts as a distracting factor, leading to changes in gait patterns similar to those caused by other distracting tasks.
A new approach to fall prevention in care homes, called the 'Guide to Action to prevent Falls in Care Home' programme, has been shown to significantly reduce falls among residents. The study found that this intervention reduced falls by over 43%, while also being cost-effective and improving quality of life.
Plant scientists can now image above and below-ground structures with unprecedented clarity, revealing new insights into biological processes. The development of three-dimensional X-ray microscopy enables the observation of microscopic molecular and cellular processes driving plant phenotypes.
New 3D printed sinusoidal spacers successfully decrease membrane fouling by an additional 10% compared to conventional spacers. The design addresses the issue of local dead zones, which can promote membrane fouling.
Researchers discovered that strigolactones enhance tomato heat and cold tolerance by inducing related genes, antioxidant metabolism, and ABA biosynthesis. This finding provides insight into the critical role of strigolactones in stress tolerance mechanisms.
Cases of new-onset anorexia nervosa among children and adolescents in Canada increased significantly during the first wave of the COVID-19 pandemic. The study found a notable rise in hospitalizations for newly-diagnosed anorexia nervosa or atypical anorexia nervosa.
A recent study uses machine learning to rapidly discover bacterial isolates with antifungal properties, identifying promising new compounds for crop protection. The approach analyzes thousands of microbial genomes at once, allowing researchers to identify novel beneficial microbes and bypass traditional screening tactics.
Researchers used mathematical models and genetic analysis to identify key gene regulators that can switch aggressive basal-like breast cancer into less dangerous luminal-A. This approach could lead to novel therapeutic targets for treating many other types of cancer.
Researchers at the University of Oklahoma have discovered a new protein fragment that could improve cartilage regeneration and reduce the need for osteoarthritis treatments. The protein fragment, developed by Handan Acar and Amgad Haleem, aims to help the body heal itself by elicititing a response from stem cells.
A new study is investigating the immune response to COVID-19 vaccines and vaccine hesitancy among three First Nations communities in Canada. The study aims to explore the effectiveness and safety of COVID-19 vaccines in these communities, with a focus on addressing historical and colonial health disparities.
Researchers at University of California San Diego found a way to boost innate immunity in liver cancer, making tumors highly responsive to immunotherapy. The combination of anti-PD-L1 antibody and polyIC molecule showed remarkable synergistic effects in liver tumor inhibition.
Researchers used ultra-high-resolution CT to assess new bone formation in 123 patients with cochlear implants. New bone formation was detected in 83% of patients and correlated with long-term residual hearing loss. The findings highlight the need for improved detection and monitoring methods.
Researchers at Drexel University found a 61% decline in new COVID-19 cases after closing indoor dining during the first two waves of the pandemic. Closing indoor dining could be a tool to curb the spread of new variants globally, alongside other measures such as vaccination and social distancing.
The new method can boost the potency of drugs reaching their target, increasing the effectiveness of treatments and reducing side effects. With the potential to personalize treatment and optimize doses, this technology may eventually change the current dosage needed for patients.
A scoping review highlights the evolution of video-based telemedicine for chronic kidney disease management, showing improved clinical outcomes and patient satisfaction. However, access to broadband internet and technology literacy remain significant barriers.
A new global-scale analysis shows that phenological changes are lagging temperature change, especially in human-dominated landscapes. Human activities such as population density and land-use types play a key role in this mismatch.
A new test has been developed to reveal bacterial contamination in dairy products, using a biosensor that triggers a change in a tasteless patch when pathogens are detected. The technology can be adapted to detect common food pathogens and is expected to significantly reduce food waste.
Studies in mouse models found that maternal immune activation can alter brain development and lead to autism-like behavioral symptoms. The research also revealed a link between maternal microbiome changes and offspring's susceptibility to intestinal inflammation, with increased IL-17a production by T cells.
A new study suggests that Denisovans arrived on the Tibetan Plateau around 160,000 years ago and contributed to the adaptation of modern humans to high altitudes. Genetic analysis reveals that Denisovans passed on genes such as EPAS1, which improves oxygen transport in the blood, to modern Tibetans.
Investigators at Weill Cornell Medicine identified significant age-related differences in tumor characteristics across various cancers, suggesting potential for personalized treatment approaches. They found that tumors from younger patients showed advanced signs of aging and more mutations associated with aggressive disease.
A large field hospital study shows that a rapid Covid-19 test is as accurate as PCR detection, with high sensitivity rates for both symptomatic and asymptomatic patients. The rapid antigen test's ease of use, time savings, and cost effectiveness make it an ideal solution to reduce testing disparities in medically underserved communities.
Researchers used imaging mass cytometry to analyze protein expression and cell location in tumor samples. High density of antigen-presenting cells with high PD-L1 and IDO expression was associated with higher pathological complete response rate in patients treated with atezolizumab plus chemotherapy.
A new study found that a college-in-prison program significantly reduced recidivism rates among participants, with rates falling by 38% across racial groups. Higher levels of program participation correlated closely with lower rates of recidivism, addressing racial inequality in prison populations.
Scientists at Tokyo University of Science have developed a novel polymer-based hydrogel that can prevent postoperative pancreatic fistulae, a frequent complication of pancreatic surgery. The Exceval hydrogel shows great promise for clinical applications due to its adjustable properties and high absorption abilities.
The study found that flu vaccination rates are significantly lower among individuals without regular healthcare providers compared to those with a provider. Vaccination rates increased with age and were higher among those with more medical conditions.
The study found clear differences in bacterial community composition and functional profiles between healthy and diseased sites, with specific taxa associated with periodontal disease progression. The identification of key bacterial species and functions involved could help prevent permanent damage.
A recent study used computer vision algorithms to analyze nearly 9,400 Flickr photos taken along Colorado's Front Range, identifying preferred outdoor landscapes with moderate accuracy. The algorithm performed well for images of water, structures, and agricultural lands, but struggled with forests. Combining social media data with on-s...
Researchers found that neighborhoods with greater racial and socioeconomic disparities are more likely to experience closures, but suburbs with gentrification show different patterns. The study suggests that the effects of school closures depend on the types of neighborhoods affected.
Astronomers used the VLA to reveal a double helix structure in the magnetic field of M87's jet, tracing material out to nearly 3,300 light-years. The findings suggest that instabilities in the flow of material within the jet could produce the observed double-helix structure.
A recent study, published in JAMA Network Open, investigated the relationship between food insecurity and allostatic overload in older adults. Researchers found that food insecurity is associated with increased allostatic overload, which can have negative effects on health outcomes.
Researchers have identified hundreds of tiny llama antibodies called nanobodies that target the SARS-CoV-2 spike protein, which current therapies do not address. Combining these nanobodies into cocktails could create potent treatments against new variants, including Omicron.
Researchers developed photoswitchable label proteins to visualize small numbers of cells in live organisms, enabling improved understanding of diseases like the immune system or tumor development. They also created sensors for optoacoustic and super-resolution imaging to visualize small molecules or ions at nanometer resolution.
A large-scale study found that regular physical activity significantly reduces the risk of developing pneumonia and dying from it. The research, led by the University of Bristol, analyzed data from over 1 million participants and showed a strong association between exercise and reduced risk of pneumonia-related death.
A PSU study reveals that parents' STEM backgrounds significantly impact their children's likelihood of majoring and persisting in STEM fields. Researchers identify STEM-specific cultural capital as a key factor, highlighting the importance of parental involvement in fostering STEM values and habits.
A new study reveals how design bias can affect medical data used in artificial intelligence tools and personalized healthcare. The research highlights the need for more inclusive recruitment strategies to ensure diverse patient populations are represented.
Swati Singh, a UD assistant professor of electrical and computer engineering, has received a $400,000 NSF CAREER award to explore new methods for studying the dark sector. She aims to develop precision measurement systems to detect astrophysical signals using mechanical devices operating in classical and quantum realms.
In a phase III trial, elacestrant showed significant benefits in decreasing death or disease progression and increasing progression-free survival compared to standard of care. The treatment was well-tolerated with manageable side effects, offering hope for patients with ER-positive/HER2-negative metastatic breast cancer.
Researchers analyzed 131 scientific papers on penguin movement at sea to highlight the need for conservation and restoration of marine biodiversity. Penguins' use of areas beyond national jurisdiction varies by species, with some undertaking spectacular migrations.
A daily dose of yoghurt has been found to be associated with lower blood pressure in individuals with hypertension. The study, conducted on 915 community-dwelling adults, found that even small amounts of yoghurt were linked to significant reductions in blood pressure.
Microglia, the brain's immune cells, migrate to the retina using blood vessels as pathways and require neurogenesis for colonization. The study provides insights into microglial migration and its implications for neurodegenerative diseases.
Researchers at Hokkaido University and Texas A¼M University identified a key mechanism used by SARS-CoV-2 to evade host immune systems, targeting the MHC class I pathway. The study found that the virus suppresses the activation of this pathway using the ORF6 protein, allowing it to persist in the body and infect others.
A UConn study found that supporting surviving parents can reduce youth suicide risk by combating negative self-views in bereaved children. The Family Bereavement Program improved parenting skills and needs, leading to reduced aversive self-views and increased child positive connectedness.
Researchers have identified a specific gene signature associated with severe COVID-19, enabling early detection of high-risk patients through non-invasive blood tests. The breakthrough could revolutionize patient triage and improve healthcare outcomes during future pandemics.
A study predicts that 6,150 km of new Pacific salmon habitat will emerge in the Pacific mountains by 2100, with most occurring in Alaska and the transboundary region. This newly formed habitat can support rapid colonization by salmon populations, offering local opportunities for some species but posing challenges under climate change.
Researchers have successfully derived stem cells from pigs, sheep, and cattle embryos grown under chemically defined conditions, paving the way for the mass production of cell-cultured meat. This breakthrough enables the creation of lab-grown food products with improved consistency and safety.
A recent study published in the American Journal of Clinical Nutrition found that consuming a pro-inflammatory diet is associated with a higher risk of developing frailty in middle-aged and older adults. Regularly eating anti-inflammatory foods such as fiber and antioxidants may help prevent frailty, according to researchers.
Researchers at City University of Hong Kong have discovered a new type of sound wave that vibrates transversely and carries both spin and orbital angular momentum like light. This finding provides new degrees of freedom for sound manipulations, enabling unprecedented acoustic communications and sensing capabilities.
African and Asian primates evolved stronger resistance to cobras' venoms, while Madagascan Lemurs and Central and South American monkeys lacked this defense due to reduced eyesight