Researchers propose that luxury goods possess a unique trait of being durable, allowing consumers to buy fewer, higher-end products that will last longer. Marketers can help consumers focus on durability by emphasizing the long-lasting nature of high-end products.
A collaboration between Michigan State University, Spectrum Health, and Niowave is testing a new radiotherapy approach for bladder cancer. The therapy combines radiotherapy with immunotherapy, which helps the patient's immune system fight off disease, aiming to improve safety and effectiveness.
Insilico Medicine will present its latest results in modern and next-generation AI for generative chemistry at ACS Spring 2021. The company's Chemistry42 platform facilitates the discovery of novel small molecule leads in several therapeutic areas, integrating AI techniques with computational and medicinal chemistry methods.
The film IN SILICO chronicles the ambitious quest to simulate the human brain on supercomputers, exposing controversy and ego in the scientific process. It encourages critical evaluation of brain research and technology, highlighting the need for a more nuanced approach to neuroscience.
Researchers replaced regenerator materials with activated carbon, increasing cooling capacity and reducing temperature fluctuations. The use of superactivated carbon particles enabled the creation of a low-cost alternative to precious metals.
A study published in Radiology found that chest CT scans can assess body composition and predict mortality risk in people with chronic obstructive pulmonary disease (COPD). Higher intermuscular fat was linked to higher mortality rates, while subcutaneous adipose tissue was associated with lower risks.
Patients with kidney failure undergoing hemodialysis developed a positive antibody response after COVID-19 vaccination, but at lower levels than healthy individuals. The findings highlight the need to reconsider vaccination schedules for this patient group.
Subgenome fractionation determines hybrid vigor in maize, with one subgenome experiencing more gene loss than the other. This leads to increased protein accumulation and a nonadditive effect on heterosis in F1 plants.
A novel cancer diagnosis technique using circularly polarized LEDs can detect precancerous lesions and early cancer, providing valuable information for treatment decisions. The method uses spin-LEDs to emit circularly polarized light, which interacts with healthy and unhealthy cells differently.
New research from Trinity College Dublin suggests a correlation between increasing Sika deer populations and higher local bovine TB infections in Ireland. The study found that County Wicklow is a hotspot for both Sika deer and TB infections.
The University of Alaska Fairbanks will establish a new research observatory in Gakona, Alaska, to explore the upper atmosphere and geospace environment. The observatory will use instruments such as the Ionospheric Research Instrument and lidar to study space weather and its effects on Earth's ionosphere and magnetosphere.
Researchers have identified key mechanisms that enable cancer cells to resist therapies targeting mutated KRAS protein. The findings suggest a potential role for rational drug design and combination therapy in overcoming resistance.
The study describes clinical characteristics of multisystem inflammatory syndrome in children associated with the COVID-19 pandemic, including age range and symptom severity. Key findings highlight the importance of early detection and effective management to prevent long-term consequences.
The University of Arkansas has been awarded a $10.8 million NIH grant to establish an integrative metabolic research center, focusing on diseases like cancer, diabetes, and obesity. The center will combine expertise in advanced imaging, bioenergetics, and data science to explore the role of cell and tissue metabolism.
A large study found that nearly 30% of patients with coronary artery disease have diabetes, significantly higher than the general population. Patients with heart disease and diabetes had worse outcomes, including a 38% higher risk of death during a five-year follow-up.
A new polymer-based battery can charge in seconds, outperforming traditional lithium-ion batteries. It is also safer and has a lower environmental impact due to the use of nickel instead of cobalt.
Scientists at Johannes Gutenberg University Mainz developed a novel implantable sensor using color-stable gold nanoparticles that report concentration changes of substances in the body through color changes, enabling long-term monitoring of disease progression and therapeutic success.
Researchers discovered a 800-meter diameter comet nucleus with large grains of phyllosilicate, similar to talcum powder, and evidence of organic molecules. The team used the Subaru Telescope to observe thermal infrared radiation, indicating the surface temperature had reached over 330 degrees Celsius in the past.
Epidemiological studies confirm that transportation noise increases cardiovascular morbidity and mortality, leading to ischaemic heart disease. The authors review the effects of noise on vascular dysfunction, inflammation, and hypertension, highlighting the need for noise-mitigation efforts and legislation.
A study by LSU Health New Orleans identified how Zika virus disrupts neuronal development, leading to microcephaly and blindness. The research team found that a molecular motor called Kinesin-5 is targeted by the Zika protease, which causes cell division disruptions and loss of function.
A new study finds that starting your day with a quick morning reflection can make you a better leader, even if you're not in a leadership role. Researchers suggest taking just a few minutes to reflect on who you want to be as a leader and how you can help others.
Researchers aim to create implant surfaces with antibacterial features, inspired by natural materials like insect wings and lotus leaves. The goal is to reduce prosthetic infections, which cause significant costs to healthcare systems.
Research shows that social distancing is equally important as mask wearing when people are indoors, even without coughing or sneezing. The study also highlights the need for better mask design to reduce droplet leakage and adequate ventilation systems to minimize airborne transmission.
Researchers found that spatial constraints from the surrounding environment significantly affect tumor evolution, leading to diverse mutational patterns among patients. The study highlights the importance of tissue architecture in regulating tumor growth and behavior.
A new study confirms that children with Down syndrome have a substantially increased risk of developing acute myeloid leukemia (AML) before age 5. The research found that 2.8% of children with Down syndrome were diagnosed with leukemia, compared to 0.05% of other children.
A new study expands evaluation of gene therapy for spinal muscular atrophy (SMA), a rare genetic neurodegenerative disease. Treatment with onasemnogene abeparvovec is associated with an immune response, but showed no long-term adverse effects.
Researchers at POSTECH have designed a metasurface that can control acoustic and elastic waves, achieving underwater stealth capability untraceable by SONAR. The technology also enables drastic alteration of wave propagation through curved plates, such as vibrations.
Sea urchin larvae use light to control digestion by opening and closing the pylorus, a critical component of the digestive tract. This finding suggests that early brain functions may have included regulating digestion, providing insights into animal evolution.
The 'MiningImpact' project monitors the first in-situ test of a prototype collector vehicle, assessing environmental impacts of deep-sea mining on ecosystems. The study aims to inform improved standards for mining codes, focusing on ecosystem health and biodiversity loss.
Researchers discovered novel neurocircuitry in mice that links leptin to the brain's dopamine reward system, reducing food intake. The study suggests targeting specific neurons may help treat anorexia nervosa and support dieting in obese individuals.
Researchers at NYU Abu Dhabi have developed a revolutionary technology that could dramatically improve diabetes treatment through an oral delivery system. The system uses nano-particles to deliver insulin and has been shown to be biocompatible, stable, and glucose-responsive.
Researchers developed a low-cost 3D-printed microfluidic bioreactor for real-time observation of growing organoids. The device reduced cell death and improved tissue development, enabling seven-day observations of brain organoids.
Researchers found that fruit flies use decision-making, learning and memory to escape heat, a process that challenges traditional thinking on self-driving cars. The study's findings suggest that simple navigation can contain complex behavior, paving the way for future work in this area.
Researchers at the University of Minnesota have identified a gene, Rpg7, responsible for high stem rust resistance in wild barley from Jordan. This discovery could provide valuable insights into breeding programs to combat this devastating disease affecting global cereal crops.
A University of Tsukuba study identifies a cost-effective way to promote dietitian-led patient education and lifestyle advice for chronic kidney disease management. By adjusting reimbursements and incentivizing general physicians, the intervention can slow CKD progression and extend patients' lives.
Researchers developed a low-cost technology that harnesses excess grid pressure to generate electricity, reducing diesel generator use and carbon footprint. Annual savings and CO2 emissions reductions reached €2,400 and up to 9 tons respectively, benefiting farmers in off-grid areas.
Research by the University of Granada found that women experiencing stress before conception are almost twice as likely to give birth to a girl. Higher cortisol levels in hair were also detected in mothers who gave birth to girls, suggesting a possible biological mechanism.
Researchers found that patients with medical risk factors or from underserved communities opted for telehealth appointments, which led to fewer diagnostic tests and medications. Despite the benefits of increased access to care, researchers note potential pitfalls and plan to examine patient outcomes.
A study found that young people with autism spectrum disorder adapted better than expected to lockdown conditions, improving their communication and relationships with families. Technological support and increased family time also played a role in their well-being.
Researchers determined the structure of Glycine Transporter 1, a protein responsible for glycine uptake in neurons. The discovery could lead to developing inhibitors targeting this protein to treat schizophrenia and other psychiatric disorders.
Satellite images reveal 35 years of changes in North Carolina's Albemarle-Pamlico Peninsula, showing 11% of tree cover taken over by ghost forests. Extreme weather events contribute to the spread of saltwater inland, poisoning soils and killing tree species.
Across most of the western US, dry periods between rainstorms have become longer and annual rainfall has become more erratic over the last 50 years. This is according to a new study that used actual rainfall data from 337 weather stations, revealing changes in drought length and rainfall patterns.
A study by McGill University found that Canadians exposed to US-based information on social media are more likely to consume and spread COVID-19 misinformation. The researchers analyzed the behaviors of 200,000 active Canadian Twitter users and found that exposure to US news outlets was associated with misperceptions about COVID-19.
Research reveals enhanced western Pacific MJO-related convection during the 2015/2016 super El Niô event. The warm SST anomaly was located more westward than previous events, leading to increased moisture and air temperature in the central-western Pacific.
An international study reveals that the MutS protein, known as the guardian of our genome, coordinates the essential DNA repair process from beginning to end. The researchers used cryo-electron microscopy to visualize the protein and describe its mechanism of action.
A study published in Radiology found that digital breast tomosynthesis (DBT) reduces the rate of interval cancers, which are more aggressive than screen-detected cancers. The study suggests that DBT may contribute to lower breast cancer mortality by detecting rapidly growing cancers with poorer prognosis.
A study conducted by researchers at the Universitat Oberta de Catalunya found that family meal routines, such as sharing food and engaging in pleasant conversation, contribute to healthier eating habits among adolescents. The Mediterranean diet's emphasis on conviviality is crucial for promoting a healthy lifestyle.
UC Riverside researchers identified a gene, RCB, that enables plants to sense heat and respond accordingly. This discovery is crucial in developing heat-tolerant crops to address the impact of global warming on crop yields by one-third by 2050.
Researchers used coda wave interferometry to determine the location of underground chemical explosions and characterize damage caused by an explosion. The technique can improve estimates of larger explosion locations and put a limit on damage extent.
Researchers at Nagoya University discovered a DNA-like molecule called XNA that could be synthesized without enzymes, supporting the hypothesis of an XNA world before the RNA world. The findings suggest that XNAs can carry genetic code stably and potentially transfer genetic information between DNA and RNA.
Scientists identified microRNA-29 as a powerful controller of brain maturation, which was found to be depleted in mice with autism-like symptoms. The study suggests that boosting levels of miR-29 could lead to therapeutic strategies for neurodevelopmental disorders like autism.
A global study has revealed that aquatic invasive species have caused significant economic losses, with an estimated $345 billion in damages since the 1970s. The study found that the largest costs were reported in North America and Asia, mainly due to damage to infrastructures, fisheries, and healthcare systems.
A recent study published in the Canadian Medical Association Journal highlights the need to rethink antihistamine use, as millions worldwide take these medications incorrectly. The study emphasizes that newer generation antihistamines are safer and more effective than first-generation antihistamines.
Valerie Bryson's new book argues for an inclusive form of socialist feminism that prioritizes women with multiple disadvantages. The discussion featured a panel of inspirational women who shared their personal journeys and experiences with feminism, highlighting the importance of intersectionality and activism.
Researchers at UVA Cancer Center discovered that antibody approaches targeting death receptor-5 could be revived by co-targeting negative biological processes with immune-activating therapy. This combination therapy increased the effectiveness of cancer killer immune cells, shrinking tumors and improving survival in lab mice.
A study published in eLife suggests that high social status contributes to accelerated aging in male baboons, with higher body mass index and increased physical demands being key factors. In contrast, early life adversity is not a significant predictor of premature aging.
Archana Kamal, a physics professor at UMass Lowell, has received over $1 million in funding from the NSF and Air Force for her research on quantum information processing. Her project aims to develop self-correcting qubits using quantum reservoir engineering to address decoherence issues.
Researchers create a microfluidic probe that generates free radicals with controlled size and concentration, allowing them to manipulate small areas on cellular surfaces. This approach enables the study of cell reactions to radicals in a controlled way, opening up new possibilities for subcellular research.
Research by ASU researchers finds that Kenyan Turkana pastoralist warriors experience PTSD symptoms similar to Western combat veterans, but with lower rates of depressive symptoms. The study suggests that aspects of Turkana military organization and practice may contribute to the difference.
The discovery of four double quasars offers insights into galaxy formation and the evolution of supermassive black holes. Quasars are brilliant beacons that can outshine entire galaxies, and their proximity in merging galaxies provides a unique window into the early universe.