A recent study has deepened our understanding of the SARS-CoV-2 nucleocapsid protein's interactions with genetic material, offering potential avenues for developing effective treatments. The research reveals how the N protein binds to RNA and protects it, and highlights its flexibility as a key factor in this process.
A new interactive tool, SpillOver, prioritizes wildlife-origin viruses based on their risk of spreading to humans. The tool identifies 12 known human pathogens and several newly discovered viruses as being at high risk of spillover.
A new study finds that restoring Louisiana's coastal marshes can store significant amounts of carbon in the soil, potentially altering the global carbon budget. The study examined 24 sites across four marsh habitats and found that protecting these areas is vital to preserving carbon stored in the soils.
The consortium, which includes 32 national medical societies representing over half of America's doctors, will advance climate, health, and equity solutions. The funding supports partnerships with the National Medical Association and empowers doctors to convey the impact of climate change on public health.
Researchers have identified compounds in Baltic amber that show activity against gram-positive, antibiotic-resistant bacteria. These compounds, including abietic acid and dehydroabietic acid, could lead to new medicines for treating infections caused by these resistant bacteria.
Researchers have created a precise map of brain connectivity from the basal ganglia, revealing new details and a surprising level of influence connected to the basal ganglia. The findings offer a blueprint of the area's architecture that could potentially open additional avenues for intervention of Parkinson's disease and other disorders.
A Norwegian University of Science and Technology study found that regret does not contribute to changes in sexual behavior. Women tend to regret casual sex more than men, while men regret missing opportunities more. The researchers suggest that personality plays a significant role in shaping behavior, rather than emotions like regret.
Research using three mouse models of neurodevelopmental disorders found distinct basal metabolism patterns, with varying energy expenditure and fat utilization. The studies suggest all three models may exhibit mitochondrial dysfunction, highlighting the need for personalized treatments and diagnostic methods.
A collaborative team identified multiple genes with recurrent alterations in uLMS, including HRD, ALT, C-MYC/BET, and PI3K-AKT-mTOR pathway, as potential targets for new treatments.
Injections of reflective sulfate aerosols into the atmosphere may relieve worst climate change consequences when combined with carbon emission reductions. However, SAI carries its own risks, affecting multiple environmental factors in complex and unpredictable ways.
Researchers found that high biodiversity in aquatic ecosystems is essential for meeting human needs for micronutrients like calcium and iron. Seafood from biodiverse sources can help combat 'hidden hunger,' a phenomenon where people have access to enough calories but not enough nutrients.
Researchers at NIH/National Human Genome Research Institute developed a breath test to measure how well patients with methylmalonic acidemia respond to liver or combined liver and kidney transplants. The test assesses the severity of the disease and helps determine treatment efficacy.
A new study published in JCI Insights found that COVID-19 convalescent plasma treatment with high levels of antibodies is safe and significantly improves clinical outcomes. The treatment was effective in non-mechanically ventilated patients, with a survival rate of 88.9% at the 30-day mark.
Researchers used single-cell RNA sequencing to track genetic activity in nearly 20,000 cells as they formed an Arabidopsis leaf. They found a surprising abundance of ambiguity in how cells traversed various identities, particularly early on within the stem cell population. The study reveals that cells may double-back on their developme...
Researchers at Kumamoto University found that adult nocturnal fishflies feed on pollen at night, visiting flowers and feeding on nectar. This discovery sheds light on the terrestrial life of adult fishflies, which was previously unknown.
A new paper explores the impact of bridge construction on manatee populations, highlighting entanglement risks and habitat destruction. DISL researchers offer best practices to reduce negative effects.
A South Korean research team has developed a high-efficiency flexible thermoelectric device capable of autonomously generating electricity from body heat. The device features a sponge-like configuration that enhances thermal insulation, allowing it to perform better than existing flexible thermoelectric devices.
Researchers developed a new method to detect multiple types of DNA methylation in individual bacteria and the gut microbiome using nanopore sequencing. This breakthrough enables reliable methylation discovery and high-resolution microbiome analysis.
Researchers at Tel Aviv University reconstructed the nutrition of stone age humans, finding they were specialized carnivores with a high-fat diet. The study used multiple lines of evidence, including genetics, metabolism, and archaeology, to conclude that humans evolved as apex predators for two million years.
A new interactive technology called LotusMenu uses rotational motion to control a 3D menu, reducing fatigue and increasing user efficiency. The study shows significant improvements in completion time and user experience compared to traditional linear menus.
Researchers from the University of Granada and the University of Cádiz have developed a computer system that can help film scriptwriters create successful storylines by analyzing common tropes in films. The system uses artificial intelligence to predict which narrative devices or plot twists are likely to work well with audiences.
A large health system study found a significant association between SARS-CoV-2 testing and an increased incidence of outpatient and hospital-associated blood clots in adults. The 30-day risk was higher for women and individuals with certain underlying medical conditions.
A large multi-center study trains convolutional neural networks to classify breast lesions from ultrasound images, achieving high accuracy rates. The model's performance is compared to that of experienced ultrasonologists, showcasing the potential of AI in speeding up early cancer detection and reducing workload.
Harvard University researchers have extended the lifespan of a dipolar molecule, enabling stable qubits for quantum computing and simulation applications. The new method allows for controlled individual atom interactions, granting scientists a key resource for molecule-based quantum information processing.
Rates of prolonged pediatric mental health ED visits increased over a decade, from 16% to nearly 25%, with Latinx children facing longer wait times. The study emphasizes the need for policy solutions to address provider shortages and expand coverage for mental health services.
A team of researchers from Shanghai Jiao Tong University has developed a new way to break the Abbe diffraction limit and realize subwavelength imaging in an all-optical manner. By utilizing nonlinear four-wave mixing, they create super-resolution through scattering of evanescent fields into the far field.
A team of experts, including Phoebe Zarnetske and Jessica Gurevitch, investigate the ecological impacts of reflecting sunlight to cool the planet. Their research highlights the complexity of cascading relationships between ecosystem function and climate under different scenarios.
A new study found that certain high blood pressure medications prescribed to people with HIV may alter their heart risk, particularly those taking beta-blockers. Researchers suggest ACEi/ARBs and diuretics as safer alternatives.
Researchers at Cornell University have developed a new type of battery that uses aluminum, offering up to 10,000 error-free cycles and potentially replacing lithium-ion batteries. This innovative technology could provide a safer and more sustainable alternative for energy storage, addressing the challenges of intermittent solar energy.
A Rutgers University-led study finds that overfishing is unlikely to be the primary cause of genetic changes in Atlantic cod. Instead, researchers suggest that addressing environmental factors such as climate change and reducing fishing pressure may be more effective in allowing cod populations to recover.
A new study found that nearly two-thirds of males and more than one-third of females with psychiatric disorders at the time of detention still had a disorder 15 years later. The findings highlight the need for expanded mental health services during detention and upon release.
Researchers found that liver disease primary biliary cholangitis triggers a signaling cascade in skin cells, leading to the formation of micro-RNA bubbles that signal itching. The discovery could lead to new treatments for severe itching and potential liver disease markers.
Researchers at Oak Ridge National Laboratory have developed a refractory metal alloy that can withstand extreme temperatures and is viable for additive manufacturing. The team also created an electrocatalyst that enables the conversion of water and carbon dioxide into higher weight hydrocarbons, set to reduce fuel costs.
Researchers at NIST have developed an atom-based sensor that can determine the direction of incoming radio signals, a crucial component for atomic communication systems. The sensor uses Rydberg atoms to measure phase differences and calculate signal arrival angles, offering advantages in accuracy and universality.
Kessler explores the psychological impact of food on art, revealing how paintings like Vollon's 'Mound of Butter' and Manet's 'Fish (Still Life)' evoke anxiety and discomfort. Her research sheds new light on the cultural significance of food in 19th-century France.
Approximately 40,000 children in the US may have lost a parent to COVID-19, facing trauma, depression, and economic insecurity. The researchers suggest equal national efforts are needed to provide supports and counseling to these vulnerable children.
A recent study found that end-of-life care for people with ovarian cancer has not improved significantly since 2007, with Black patients experiencing higher rates of emergency department visits and intensive treatment. Palliative care recommendations have been included in guidelines, but its adoption remains limited.
A clinical risk assessment tool was tested on Spanish patients to predict critical illness among those hospitalized with COVID-19. The study found that the tool accurately identified high-risk patients, highlighting its potential for early intervention.
A new study published in The Journal of Psychosomatic Obstetrics & Gynecology found that nearly 11% of men experience anxiety during the perinatal period, with rates higher during postpartum than pregnancy.
A recent study published in Psychology of Addictive Behaviors found that 80% of Americans with resolved drug problems report significant personal achievements, including self-improvement, family engagement, and civic participation. These achievements accumulate over time and are associated with greater happiness and quality of life.
A new genetic test has been developed by U of M researchers to identify Palmer Amaranth, which can cause significant yield loss in corn, soybean, and cotton crops. The test, which shows 99.9% accuracy, could be commercially available by the end of 2021.
Scientists at Berkeley Lab have discovered a self-improving property in Si/GaN that enables it to become more efficient and stable as an artificial photosynthesis device. The material, made of silicon and gallium nitride, can harness sunlight into carbon-free hydrogen with twice the efficiency and stability of previous technologies.
A study examining remote cardiology clinic visits during COVID-19 found disparities in patient use of care, diagnostic testing, and medication prescribing. The transition to remote visits was associated with uneven access to care, highlighting the need for improved healthcare infrastructure.
The study provides valuable insights into heart, lung, blood and sleep disorders, shedding light on human evolution and genetic mutation. The analysis identified 400 million genetic variants, with over 78% never described before, offering potential for new treatments and prevention strategies tailored to individual patients.
Researchers have discovered that nuclear speckles work in partnership with p53 to boost the activities of specific sets of genes. This finding may lead to a better understanding of cancers and potential cancer treatments. The study suggests that nuclear speckles are major regulators of gene expression.
Case report describes two patients who underwent a successful second dose of the Moderna vaccine using a graded dosing protocol after experiencing immediate hypersensitivity reactions. Both patients responded well and developed IgG antibodies, suggesting effective vaccination despite the modified dosing schedule.
A study of 80 people shows that prenatal exposure to proinflammatory cytokines is associated with different responses to stressful stimuli in adults. Women prenatally exposed to cytokines have altered brain activity and connectivity compared to men.
The Bureau of Reclamation released final technical reports supporting the Water Reliability in the West - 2021 SECURE Water Act Report, assessing climate change impacts on 17 western states. The reports provide detailed information on adaptation strategies to increase water supply reliability.
Researchers have developed DeepTCR, a software package that employs deep-learning algorithms to analyze T-cell receptor sequencing data. The software can identify patterns in the receptors that confer the function of the T cell to recognize and kill pathological cells.
Scientists develop a quantum annealing framework to solve the long-standing problem of ion diffusion in solids. The approach shows promising results, especially when compared to other computational techniques, and could expand materials science.
Remote workers can benefit from setting clear boundaries between their personal and professional lives, according to Rensselaer Polytechnic Institute professor Timothy D. Golden. Effective communication with family members and managers is crucial for maintaining a healthy work-life balance while working from home.
A Stanford University study reveals that traits like skin pigmentation reveal little about genetic ancestry over time, regardless of mating scenarios. The researchers used a mathematical model to understand the decoupling of ancestry and traits, with implications for understanding social meaning of physical traits.
Researchers discovered a cell-to-cell communication network that instructs tumor cells in tissues to regrow after genotoxic therapy. The study found that elevated p53 levels and release of interleukin-6 signal cells to activate growth signals, leading to tumor regrowth.
Researchers developed an exosome-coated stent that heals vascular injury by delivering regenerative stem cell-derived therapy to ischemic tissue. The stent reduces restenosis and promotes endothelial coverage compared to traditional drug-eluting and bare metal stents.
Researchers have developed a new method using ion mobility-mass spectrometry to detect existing and emerging dopants in urine samples. This approach aims to characterize and identify banned substances, including steroids and glucocorticoids, and potentially predict the structure of newly created illicit steroids.
A new study finds that Medicaid expansion significantly improves access to evidence-based treatments for opioid use disorder among those involved with the criminal justice system. However, disparities persist due to incarceration-related stigma and barriers to treatment.
A new analysis by researchers led by Dr. David Nerenz of Henry Ford Health System suggests that accounting for social risk factors like poverty, housing instability and transportation insecurity can have a meaningful impact on healthcare quality measures without compromising quality of care. The study makes the case for using social ri...
Researchers estimated that COVID-19 death of a parent affects approximately 18 million US children. The study used data from the National Vital Statistics System to project the number of affected children.
Scientists at Temple University and Case Western Reserve University will explore the role of nitric oxide in controlling the beta-adrenergic receptor system, a key player in heart function. The insights gained could lead to new therapies for congestive heart failure.
Researchers investigated the association of sociodemographic factors, including age, sex, ethnicity, and socioeconomic status, with the risk of SARS-CoV-2 infection. The study found a significant link between certain blood types and increased risk of severe COVID-19. Participants with type O negative blood were more likely to experienc...