Researchers developed a new material that fills a crucial gap in the electronic material library. The ultrathin beta-tellurite oxide has high mobility and is highly transparent, enabling fast and efficient devices.
A study published in JACC reveals that clonal hematopoiesis, a phenomenon where acquired DNA mutations accelerate heart failure progression, is an independent risk factor. The presence of specific mutant clones, including those with TET2 and DNMT3A mutations, increases the risk of hospitalization and death from heart failure.
A novel nanoparticle vaccine, called spike ferritin nanoparticle (SpFN), is being tested in a Phase 1 clinical trial at WRAIR. The vaccine has shown promise in inducing potent and broad neutralizing antibody responses against SARS-CoV-2 variants.
Dr. Kiana Aran's new technology, CRISPR-SNP-chip, detects single nucleotide polymorphisms without amplification, revolutionizing genetic research and diagnostics for diseases like Sickle Cell Disease and ALS.
A unique head-mounted mini-microscope device has enabled researchers to image complex brain functions of freely moving mice in real time over a period of more than 300 days. The device, known as the mini-MScope, allows holistic imaging of much of the mouse brain surface and captures connections between regions across the cortex.
A USC study projects significant savings for US state Medicaid programs if treatments helping patients with Alzheimer's disease live independently longer are introduced. The study forecasts annual savings of $7.4 billion in 2030 and over $22 billion by 2040, preventing over one million patient-years of nursing home use.
Researchers at KAIST develop M3I3 Initiative to speed up materials development using multiscale/multimodal imaging and machine learning. The team creates a quantitative model using machine learning and presents a future outlook for advancements in materials science.
Researchers found that skeletal muscle satellite cells proliferate better in low glucose environments, contrary to conventional wisdom. This discovery could lead to significant breakthroughs in biomedical research and the development of new treatments for muscle loss associated with diabetes.
Researchers from Nagoya University developed a two-step labeling technique to analyze the dynamics of neurotransmitter receptor proteins. The study revealed key findings on AMPA-type glutamate receptors, including their localization at synapses and half-life in neurons.
Researchers developed a safe and cheap technology to disinfect packed eggs with an electron beam. The technology kills bacteria without affecting the quality of meat or eggshell composition. Healthy chickens emerge from disinfected eggs, leading to improved immunity against diseases like Newcastle disease.
Researchers evaluated thousands of policy proposals to assess feasibility and potential impact on reducing EU's contribution to tropical deforestation. Two promising policy options are implementing due diligence for importers and supporting multi-stakeholder forums.
Global Africa aims to report on various issues in Africa and worldwide, fostering international-level evaluation standards. The journal's launch is part of a program that includes training courses, pop-up seminars, and conferences to cultivate African research production and dissemination ecosystem.
Researchers suggest most of Earth's carbon was delivered from the interstellar medium, avoiding vaporization entirely. This discovery sheds light on the origin of life on Earth and suggests a delicate balance between too little or too much carbon for habitability.
Researchers used X-ray microscopy to analyze lithium batteries and employed machine learning to speed up the learning curve about process that shortens battery life. Infrared microscopy also goes off-grid with new technique, enabling time-sensitive experiments and broadening biological spectromicroscopy scope.
Researchers from Nagoya University successfully capture images of female gamete formation in Arabidopsis thaliana, revealing how cell fate is determined and providing insights into plant adaptation. The study's findings have significant implications for understanding fertilization rates and environmental resistance in plants.
A new analysis found that only 84 of the 408 farmed species had available scientific studies on their welfare, while the majority lacked information. The researchers warn that aquaculture's expansion poses great risks to individual animal lives due to insufficient knowledge.
A VCU-led study found that regional surges contributed to higher excess death rates from COVID-19 and other causes, particularly affecting Black Americans. Excess deaths rose a staggering 22.9% nationally from March 2020 to January 2021.
A team of researchers identified 37 substances that bind to the main protease of SARS-CoV-2, a promising starting point for COVID-19 drugs. Seven substances inhibit the protein's activity, with two showing high antivirality and good cell compatibility.
A team of researchers has discovered a group of bacteria that may help fungi and plants acquire soil nutrients. The bacteria form unique communities on the hyphae surfaces of arbuscular mycorrhizal fungi, which could enhance phosphate acquisition and improve crop yields.
Researchers found that telephone poles attract flight-dispersing spotted lanternflies, which are visually drawn to turn and land on the poles. The pole serves as a visual magnet, attracting a large proportion of the insects.
Researchers discovered that transfer RNAs (tRNAs) play a crucial role in controlling the activation of the stringent response pathway. The MurM enzyme, involved in cell wall synthesis, acts as a quality control manager to ensure accurate translation and prevent toxic tRNA buildup.
Researchers have found that a chemical inhibitor called K777 can reduce the ability of SARS-CoV-2 to infect cells. Clinical trials are underway for its potential use in treating COVID-19, particularly in patients with severe cases.
A recent study from Georgia Institute of Technology found that the type of material and number of fabric layers used in homemade masks significantly affect Covid-19 exposure risk. The best-performing materials for masks were blackout drapery and sterilization wrap, which provide an overall filtration efficiency of about 50% for submicr...
A study published in JAMA Network Open found that over 60% of US adults who vape are interested in quitting, with former cigarette smokers having the highest intentions. Despite e-cigarettes being seen as a potential tool for smoking cessation, many users struggle to quit, and current treatments may not be effective for all users.
Researchers have identified a pair of microRNAs that help maintain breast cancer stem cells and drive tumor growth. Targeting these microRNAs may improve the prognosis of patients with aggressive forms of breast cancer by making cancer stem cells more susceptible to chemotherapy.
A new study found that Middle Eastern and North African individuals in Michigan are more likely to experience chronic illness, mental health issues, and poor overall health due to various barriers. The survey also highlighted the prevalence of food insecurity, transportation issues, and financial strain as major risk factors for poor h...
Researchers at Niigata University have identified a protein biomarker, APM2, that can indicate the permissible level of the chemotherapeutic drug cisplatin. The study found a significant relationship between high APM2 expression and cisplatin resistance in liver and gastric cancer cells.
Researchers identify three COVID-19 phenotypes with different comorbidities, complications, and clinical outcomes. Phenotype II showed the worst clinical outcomes, while Phenotype III had the best outcomes despite higher respiratory comorbidity rates.
A study by University of California, Davis researchers found that prioritizing vaccination for vulnerable populations like seniors and essential workers can reduce deaths, infections, and years of life lost by 17-44%. The optimal strategy depends on the outbreak conditions, including vaccine supply and transmission rates.
Researchers at Shinshu University developed an affordable portable sensor using lanthanide metal-organic frameworks (MOFs) to detect fluoride levels in drinking water. The device is compatible with local populations and can be produced locally, aiming to improve access to safe water and sanitation for all
Researchers analyzed national survey data to compare HMO enrollment rates among children with commercial and public coverage by race and ethnicity. The study reveals racial and ethnic differences in HMO enrollment rates, highlighting disparities in healthcare access for vulnerable populations.
A study in red-haired mice reveals that a variant of the melanocortin 1 receptor affects pain sensitivity. The researchers found that lower levels of certain hormones lead to more opioid signals, elevating the pain threshold.
A team of scientists developed a deep learning model that improves air quality estimates by combining satellite and ground-based observations. The model achieved higher spatial and temporal resolution, enabling more accurate predictions of nitrogen dioxide levels in the Los Angeles area.
Researchers developed a personalized tumor cell vaccine strategy targeting Myc oncogenes combined with checkpoint therapy, creating an effective immune response. In the mouse neuroblastoma model, the vaccine showed a 75% cure rate and long-term survival.
A study analyzing UK Biobank data found that deprivation is the primary driver of Covid-19 disparities among minority ethnic groups. Reducing material deprivation could play a pivotal role in decreasing these disparities and improving health outcomes.
A RAND Corporation study reveals that personal accounts from former white supremacists and Islamic extremists highlight the role of negative life events, propaganda, and social factors in radicalization. Strategies such as mental health care, diverse cultural groups, and media literacy education may aid in deradicalization.
Researchers at Chinese Academy of Sciences developed a method to deposit high-dispersed Fe species into ZSM-5 micropores, resulting in high selectivity of cyclohexanone (92%-97%) and improved catalyst activity. The Fe content can be precisely controlled by varying ALD cycles.
A study analyzing COVID-19-related deaths and all other causes in the US found that pandemic-excess mortality significantly surpassed pre-pandemic levels, resulting in a total of over 3.7 million excess deaths from February 2020 to December 2022.
A new study found that couples tend to decrease their walking speed when together, especially when holding hands. This decrease in speed can negate some of the health benefits associated with walking alone at a faster pace. On the other hand, older adults who are more active tend to maintain their gait speed.
A new University of Utah Health study reveals that healthcare workers with caregiving responsibilities are most likely to contemplate leaving or reducing hours due to the pandemic's impact on their personal lives. The findings suggest that retaining highly trained doctors and nurses could be a significant challenge for healthcare systems.
Research reveals significant decrease in subarachnoid hemorrhage (SAH) hospital admissions, as well as ruptured aneurysm coiling volume, during the pandemic's peak. Hospitals with higher COVID-19 burden showed decreases in SAH admissions, indicating access to care was not a primary factor.
Researchers found that tumors with a softer matrix are more resistant to treatment, activating signaling pathways that promote cell survival. Targeting this pathway could enhance the effectiveness of chemo- and radiotherapy.
Researchers detected anatoxin-a, a deadly cyanotoxin, in air and water near a Massachusetts pond with algal blooms. The toxin can cause respiratory paralysis, muscular twitching, and loss of coordination at high concentrations.
Assistant Professor Xin Zhang received a $500,000 NSF CAREER Award to investigate how to align stakeholder interests with nitrogen reduction goals. The research aims to improve decision-making and develop innovative solutions for sustainable nitrogen management.
Researchers have developed a kirigami technique to fabricate complex 3D nanostructures with unprecedented ease. By strategically introducing cuts to a uniform structural film, the team can create sophisticated three-dimensional structures that can change shape in response to environmental changes.
Researchers found that consumer resistance stems from the disruption of social practices, such as shopping, rather than individual behaviors. To overcome resistance, policy makers should focus on changing these practices, not just individual actions. The study provides a framework for designing practice-based sustainability interventions.
A team of scientists at the University of Pennsylvania School of Medicine has identified nine potential COVID-19 treatments, including three FDA-approved drugs. The study found that these drugs, such as cyclosporine, work by inhibiting the replication of the virus in respiratory cells and suppressing inflammation.
Researchers pinpointed cysteine leukotriene receptor 2 (CysLT2R) as a new target for treating chronic itch. The study found that activating this receptor induces itching in mouse models of atopic dermatitis, highlighting its potential role in contributing to the condition.
Researchers at Buck Institute discover non-invasive biomarker test to measure and track performance of senolytic drugs, which target multiple age-related diseases. The biomarker detects a unique lipid metabolite released when senescent cells die.
An international consortium has proposed the first general selection criteria for lung transplantation in COVID-19 patients. The criteria include exhaustion of conservative treatment options, irreversible lung damage, and good physical condition.
A study published in Spine found that patients with cannabis use disorder undergoing spinal surgery experienced higher complication rates, including stroke, respiratory issues, and prolonged hospital stays. Chronic cannabis users were also more likely to require rehabilitation facilities upon discharge.
A UTA civil engineering professor is leading a $2.8 million project to analyze the condition and remaining service life of over 3,500 lane miles through TxDOT. The team will use AI, finite element modeling, and advanced spectroscopy tools to predict pavement lifespan.
Researchers found that students who were satisfied with their meals wasted less food. Diners who visited the dining commons frequently and were familiar with the menu options also tended to waste less food. The study's results suggest that posting signs encouraging healthier choices could help reduce food waste.
A comprehensive review of early research on TV time and attention problems in children found no direct link, contrary to previous claims. The study's authors suggest that parents should not feel guilty for allowing their young children to watch TV.
The Masonic Medical Research Institute has received a $750,000 Department of Defense Lupus Impact Award to investigate the role of protein tyrosine phosphatase SHP2 in systemic lupus erythematosus. The research aims to improve treatment options and quality of life for patients with this devastating autoimmune disease.
A recent study found that combat experience is associated with a higher risk of alcohol use to cope with PTSD symptoms, but this link weakens when adjusting for PTSD severity. The study also reveals that trauma-exposed men without combat experience are more likely than those with combat experience to report an alcohol use disorder.
A survey study examined the effects of COVID-19 on healthcare employees' careers, productivity, childcare needs, and likelihood of leaving the workforce. The study found that many employees experienced burnout, reduced productivity, and increased childcare responsibilities.
Zheng and Qin et al. developed novel host-guest organic phosphorescence systems using commercially available compounds, achieving high phosphorescence efficiency and longest lifetime. The new systems utilize Förster resonance energy transfer (FRET) for improved performance.
Researchers explored how molecular changes in Alzheimer's patients relate to brain function, developed a new model for predicting life expectancy of older adults with multiple chronic diseases, and examined older firearm owners' perspectives on retiring their guns.
Researchers successfully synthesize armchair graphene nanoribbons (AGNRs) on Cu(111) via lateral fusion of poly(para-phenylene). Oxygen introduction reduces temperature required for reaction, opening up new avenues for surface chemistry. This breakthrough could benefit various dehydrogenation reactions in on-surface synthesis.