A new study from Trinity College Dublin shows that one in eight older people in Ireland require medical attention for falls annually, with significant gaps in prevention and access to specialist services. The study highlights the need for a coordinated national approach to address this growing issue.
A recent study reveals that FPR2 activation regulates the proliferation and differentiation of intestinal stem cells and transit-amplifying cells, promoting tissue regeneration. The study also identified the PKC-ERK signaling axis as a key mediator of this process.
A new study found that warmer sea surface temperatures cause loggerhead sea turtles to nest earlier and more frequently, but also reduces their reproductive output as ocean productivity declines. This shift has worrying consequences for the long-term resilience of the species.
A novel AI model has been developed to accurately detect placenta accreta spectrum (PAS) in pregnancy, a life-threatening condition often undetected by current screening methods. The model was retrospectively reviewed on 2D obstetric ultrasound images from 113 patients at high risk for PAS and found to be accurate in detecting all cases.
A recent study uses integrative omics analysis to identify key plasma proteins associated with cardiovascular diseases and magnetic resonance traits. The research reveals four high-priority candidate proteins, AGER, CCN3, FER, and SPON1, that show consistent associations with both clinical CVDs and structural CMR traits.
A new study delivers the first fully gapless, telomere-to-telomere genome assembly of flax, providing a complete genetic blueprint for advancing flax biology and breeding. The research uncovers previously hidden genes, structural variations, and evolutionary signals that shape fatty acid biosynthesis and genome organization.
A recent study questions AI model Centaur's ability to simulate human cognition, suggesting it relies on statistical patterns rather than genuine understanding.
A study from Lund University found that a climate-friendly diet rich in plant-based foods like wholegrains, legumes, fruit, and vegetables leads to better nutritional status compared to traditional diets. Despite lower meat consumption, most participants achieved sufficient amounts of key vitamins and minerals.
A new study by Radboud University and the University of Groningen found that PhD graduates, particularly women, experience a persistent pay gap outside academia. Women earn an average of 171 euros less per month immediately after obtaining their doctorate, with this disparity increasing over time.
Sorting extracellular vesicles from human adipose stromal cells using fluorescence-based flow cytometry retains key microRNAs linked to inflammation control and tissue repair. This study highlights the importance of optimizing vesicle isolation for clinical applications, balancing purity with molecular complexity.
A University of Barcelona study using animal models found that early and sustained cognitive stimulation preserves brain connectivity and memory in Alzheimer's disease. Males respond better to cognitive intervention than females, which can delay the onset of the disease.
A new study proposes a two-component self-interacting dark matter model that naturally reproduces observational results for dwarf galaxies and strong gravitational lensing. The model predicts mass segregation, where heavier particles sink towards galaxy centers and lighter particles diffuse outward.
Researchers discovered that Siglec-15 fuels brain tumor growth by interacting with the lysosomal calcium ion channel TRPML1, promoting tumor growth and survival. The study identified a novel signaling axis that could bypass drug resistance in targeted therapies.
A historical analysis of Surinamese slave registers found that young children who grew up without a mother were more likely to die, while the presence of grandmothers significantly increased their chances of survival. Family members played a crucial role in protecting children from harsh conditions.
Research on Philippine jails reveals the everyday human cost of overcrowding, including sensory overload from poor ventilation, heat, and smell. The study calls for sensorially attuned penal reform to address the full spectrum of carceral harm.
A new ceramic material overcomes long-standing limits in proton conductivity, achieving record-high performance at intermediate temperatures. The innovative donor co-doping strategy combines increased proton concentration and mobility with chemical stability under various environments.
Researchers from Mass General Brigham have identified a neural circuit linking prior experiences with current aversions and preferences when it comes to dining choices. The findings suggest that dysfunction in this brain circuit could be a factor in disordered eating and obesity, providing new potential targets for treatment.
Researchers developed an ultra-light wearable haptic device named OriRing with a three-axis force sensor, enabling high-fidelity tactile feedback. The system can deliver up to 6.5 N of force feedback, equivalent to lifting 663 g, in a compact form factor.
A new wearable textile sensor, TAESS, integrates electrocardiography and impedance plethysmography to measure core cardiovascular parameters continuously. It enables real-time tracking of blood pressure, stroke volume, cardiac output, heart rate, and systemic vascular resistance during daily activities.
Scientists propose a solution to inactivate bacteriophages without destroying bacterial strains, using polymeric nanospheres that interact with phage surface charges. The nanoparticles are effective against 95% of phages and could provide a safer alternative to existing anti-phage strategies.
Researchers at KAIST create a new technique to process semiconductor surfaces uniformly down to the atomic level using carbon nanotubes as abrasive materials. This technology demonstrates potential to significantly improve surface quality and precision in advanced semiconductor processes like high-bandwidth memory.
Researchers developed a holistic monitoring system to investigate lake ecosystems' sensitivity to boat traffic, weather, and climate change. The system, WAMOS, accurately analyzes wave patterns and assigns causes, enabling precise modeling of ecosystem effects.
The discovery of mature silver European eels in Cyprus highlights the importance of river fragmentation and local environmental conditions on eel populations. The finding also underscores the need for urgent implementation of Eel Management Plans to conserve this critically endangered species.
Researchers found that exercise changes brain activity in nerve cells called SF1 neurons, which helps muscles and hearts become stronger. This brain region plays a key role in regulating energy use and body weight.
Researchers created detailed maps of where wild ancestors of wheat, barley, and rye grew in the Middle East before farming began. The study used machine-learning and climate models to challenge previous assumptions about ancient plant distribution.
Researchers developed a fast, multi-platform compatible detection network that can detect gas leaks in three dimensions. The system achieves real-time detection at over 25 frames per second and provides accurate 3D reconstruction within 200 milliseconds.
A large randomized clinical study found that clopidogrel significantly reduces the risk of all-cause death, myocardial infarction, or stroke compared to aspirin in high-risk patients. The trial demonstrated a lower incidence of myocardial infarction without increasing bleeding risk.
A retrospective study found that higher initial MP dose is associated with improved neurological outcomes in children with ANE. This suggests a potential benefit of more aggressive treatment for this rare but fatal condition.
Gradient-engineered cathode materials exhibit improved cycling stability and rate performance, demonstrating high capacity and strong long-term durability. The composition gradient strategy precisely regulates internal stress distribution and electronic structure, suppressing undesirable oxygen-related side reactions.
A nationwide cohort study found that semaglutide initiators had a significantly higher risk of developing nonarteritic anterior ischemic optic neuropathy compared to sodium-glucose cotransporter-2 inhibitor initiators. The absolute risk was low, but clinicians and patients should be aware of this rare but evident increased risk.
The Interactions Collaboration has selected top three photographs from hundreds of submissions by amateur and professional photographers worldwide. Marco Donghia's image of a researcher at the CryOgenic Laboratory for Detectors was chosen as first place, praised for its clear storytelling and masterful use of light.
The Coastal Challenge game offers an interactive platform for exploring how choices shape coastal system resilience. Players test long-term adaptation paths while balancing ecological, social, and economic objectives.
A research team developed an AI-based optical diagnostic platform that can distinguish between nasal secretion and cerebrospinal fluid (CSF) leaking within minutes. The platform achieved an exceptionally high diagnostic accuracy of 90.8% in identifying CSF leakage, overcoming the challenge of visually indistinguishable fluids.
Researchers have developed new soft solid-state electrolytes that enable safer and more efficient batteries. The breakthrough could lead to widespread adoption of solid-state batteries in electric vehicles and other applications.
Researchers identified a gene expression signature and inflammation patterns in normal tissue near the tumor to distinguish between patients with aggressive disease. The study paves the way for early identification of high-risk patients through blood or semen samples.
A new study found that a single post-meal biomarker, 1-hour postprandial SPARC (SPARC-1H), can predict who will benefit most from adopting a Mediterranean diet. Individuals with lower baseline SPARC-1H levels experienced greater improvements in insulin resistance and fasting glucose after six months of dietary adherence.
Access to higher-level neonatal care is limited at rural birth hospitals, where less than 20% offer this care compared to 74% of urban hospitals. Urban birth hospitals are expanding higher-level neonatal care, exacerbating geographic disparities in access to care for high-risk infants.
Researchers control light emission from individual molecules, enabling future technologies like quantum computing and ultra-dense displays. The team's roadmap includes achieving stable, room-temperature single-photon emission by 2026 and integrating multiple devices for small-scale quantum information processing.
Researchers developed a reusable electro-kinetic filtration platform capable of filtering over 99% of ultrafine nanoplastics particles smaller than 50 nm. The system achieves commercial-level high-flow conditions and demonstrates energy self-sufficiency through a triboelectric generator.
A research team at HKUST has developed a novel therapy capable of preventing the onset and growth of metastatic breast cancers in mouse models by targeting glycans on cancer cells. The therapy, known as LPAT, demonstrates improved glycan discrimination compared to traditional antibody-based approaches.
A study analyzing news reports, social media posts, and internet search data during the 2022-2023 South Korea drought found that public views change depending on problem size and distance from people. Public interest, emotions, and behavior also shifted as the disaster scale changed.
A recent study found that hepatocyte-specific deletion of DDAH1 in mice attenuated fasting-induced hepatic steatosis, while overexpression exacerbated lipid accumulation. The researchers identified a novel regulatory axis involving FABP1 and AMPK/mTOR signaling pathway.
The book provides a sense of great expectations for whole-brain models to understand emergence of computation that makes us human and allows us to thrive. It presents different model-free methods to describe brain states with varying degrees of accuracy, allowing for the underlying causal mechanisms to be discovered.
A recent study reveals that discretionary foods, including sweets and soft drinks, account for nearly one-fifth of Finnish households' total food expenditure. This has significant environmental implications, contributing to climate change, freshwater eutrophication, and land use.
Temperature impacts the quality and speed of male frogs' mating calls, which are more attractive to females in warmer conditions. This study suggests that female frogs use these calls to gauge environmental suitability for reproduction.
A new study published in Nature found that hunter-gatherers in Belgium and the Netherlands adopted farming thousands of years later than elsewhere in Europe. The research suggests that migrant women played a pivotal role in introducing farming practices, bringing their knowledge and genes to the local communities.
Researchers developed a highly sensitive light-based sensor that can detect extremely low concentrations of cancer biomarkers in the blood. The sensor combines nanostructures made of DNA with quantum dots to detect faint biomarker signals, holding promise for early cancer diagnosis and personalized treatment options.
Researchers developed a new chip architecture called QARPET, which allows for the characterization of hundreds of qubits under the same operating conditions. The platform features a tiled approach to qubit measurement, making it efficient and scalable.
Researchers found a pattern of gene activity associated with higher depression risk in women who experienced childhood abuse. This discovery may help explain individual differences in risk and provide biological markers for depression.
A team of EPFL roboticists has designed a modular robot that shares power, sensing, and communication resources among its individual units, significantly increasing its resistance to failure. The approach, called hyper-redundancy, allows the robot to continue functioning even if one module fails, by compensating with neighboring modules.
Researchers developed a new MRI technique that simultaneously displays heart tissue and blood flow, enabling precise planning for surgical repairs. This innovation provides high-quality flow images without radiation, making it essential for repeated imaging in children.
During American Heart Month 2026, the National Fraternal Order of Police and the American Heart Association urge Americans to learn CPR and be initial first responders. Immediate CPR can double or triple chances of survival in cardiac arrest cases.
The Chinese Guidelines for Clinical Diagnosis, Treatment, and Management of Cirrhosis (2025) provide a comprehensive framework for diagnosing and managing liver cirrhosis. Key pathophysiological changes include impaired synthesis of albumin and coagulation factors, portal hypertension, gut-liver axis dysregulation, and progression driv...
Researchers found that plants living in areas with human activity causing population crashes have reduced genetic diversity and higher inbreeding levels. Conservationists must consider a population's history-influenced genetics alongside its size and habitat in planning.
A new study finds that nearly 1 in 3 teens have received a sext, and almost 1 in 4 have sent one. Sextortion is also common, with nearly half of teens who sent a sext reporting being targeted.
The Harvard Business School case study explores the development of Insilico's lead asset, Rentosertib, which completed a Phase IIa clinical evaluation for idiopathic pulmonary fibrosis. Insilico Medicine has significantly improved preclinical drug development efficiency with its AI-driven approach.
A new study by Binghamton University School of Management reveals that businesses can improve their performance when they openly discuss and address cybersecurity issues. The research found a positive correlation between cybersecurity readiness and firm performance, suggesting that proactive measures can lead to better outcomes.
A UC Irvine-led team has developed the most detailed maps of gene regulation in Alzheimer's disease, revealing causal mechanisms and potential new targets for treatments. The study identifies key biological pathways and genes that may drive memory loss and brain degeneration.
The study reveals that redefining the concept of electrode-electrolyte interphase layers can improve battery stability and performance. Researchers found that careful control of interphase properties through materials choice, electrolyte formulation, and binder selection can significantly extend battery life.
Studies show that a significant portion of survey responses can be false or fraudulent, while AI agents can complete polls with little supervision. To address this issue, researchers propose analyzing response patterns, vetted survey panels, and design tasks that exploit human reasoning weaknesses.