A UT Southwestern Medical Center study found that combining cognitive behavioral therapy with medication improves long-term success of depression treatment in children and adolescents. Relapse rates were significantly lower for those who received both forms of treatment compared to those on medication alone.
A study published in JAMA Psychiatry analyzed heroin use patterns from 1970 to 2014, revealing significant changes in demographics. The findings indicate that heroin users are becoming increasingly young, urban, and from lower socioeconomic backgrounds, reflecting broader societal trends.
Dr. Peter F. Buckley, a psychiatrist and Dean of the Medical College of Georgia, has been awarded the Kempf Fund Award for Research Development in Psychobiological Psychiatry from the American Psychiatric Association. The award recognizes his contributions to understanding schizophrenia and improving treatments.
People bereaved by suicide are at increased risk of suicide, depression, and mental illness compared to those affected by other sudden deaths. The Lancet Psychiatry review emphasizes the need for more comprehensive support from health and social services.
The Lancet Psychiatry article highlights the underuse of mental health resources among individuals struggling with suicidal thoughts. According to researchers, approximately 60% of people experiencing suicidal ideation or behavior do not receive treatment, underscoring the need for more effective psychological interventions and increas...
Research by King's College London found that childhood bullying has a lasting impact on adults' physical and psychological health, social relationships, and well-being. Individuals who were bullied in childhood were more likely to experience depression, anxiety disorders, and lower quality of life.
Two new studies published in Biological Psychiatry suggest that obsessive-compulsive disorder (OCD) may be characterized by a tendency to form compulsive habits, rather than irrational beliefs. Researchers found that individuals with OCD displayed impairments in goal-directed decision making and avoidance habits.
A study published in Biological Psychiatry found that intranasal ketamine conferred an unusually rapid antidepressant effect within 24 hours and was well-tolerated in patients with treatment-resistant major depressive disorder. The results show promise for a new treatment class, targeting the NMDA glutamate receptor.
Researchers at Douglas Mental Health University Institute have discovered that dopamine is present in the hippocampus and plays a key role in this region. This finding opens up new avenues for understanding psychiatric diseases such as schizophrenia and may lead to the development of new therapeutic approaches to improve symptoms.
The new center aims to develop computational methods to understand how human cognition works and how it becomes disrupted in psychiatric disorders. The centre will combine advanced brain imaging with computational approaches to identify causes of mental health problems and develop personalized treatments.
Recent years have seen progress in ASD research, with updates on genetic causes, effective treatments, and promoting success for young people with ASD entering college. The special issue of Harvard Review of Psychiatry highlights six key areas of research.
The American Academy of Child and Adolescent Psychiatry has revised key parameters for evaluating and treating autism, emphasizing early diagnosis and a team approach to care. Researchers led by Fred Volkmar recommend a coordinated medical, psychological, and communication evaluation to differentiate between autism and other disorders.
A novel approach integrating psychiatrists, psychologists, and telemedicine into primary care clinics significantly reduced psychiatric and general medical symptoms. The model has been shown to improve treatment outcomes and increase access to care for rural communities with limited mental health resources.
Research suggests that age-adjusted rates of dementia have declined for people born later, particularly those at higher risk. Lifestyle factors such as exercise and diet are being studied as potential contributors to this trend.
Researchers at Mount Sinai found long-term cocaine abuse linked to deficits in parts of the brain monitoring behavior, suggesting targeted treatments based on quantifiable biological abnormalities. The study's findings challenge clinical assumptions about addicted individuals' motivations and behaviors.
A study by Regenstrief Institute and Indiana University found that older adults with severe mental illness have a higher rate of medical emergency department visits and longer hospital stays. The study highlights the need for more intensive care models that consider psychosocial factors.
A recent study published in Biological Psychiatry reveals that offspring of stressed mothers show stress-induced changes at birth, with altered behavior and gender-related differences continuing into adulthood. The researchers identified the CRF1 gene as a key contributor to this intergenerational transmission of patterns.
A new study published in JAMA Psychiatry reveals that topiramate, an anti-epileptic drug, shows promise in treating cocaine dependence by reducing cravings and improving global functioning. The study enrolled 142 participants and found that topiramate was more efficacious than placebo.
A recent study published in the American Journal of Psychiatry suggests a strong association between prenatal tobacco exposure and an increased risk of developing bipolar disorder (BD) in adult children. The study, which analyzed data from the Child Health and Development Study, found that maternal smoking during pregnancy was associat...
Researchers found similar disturbances in cortical circuit function between schizophrenia and bipolar disorder, with individuals with schizophrenia showing more severe abnormalities. The study suggests a continuous spectrum of circuit dysfunction across the disorders.
A study published in Molecular Psychiatry found RNA biomarkers in blood associated with suicidal thoughts in patients with bipolar disorder. The researchers identified SAT1 and other markers that were significantly elevated in the blood of both bipolar disorder patients and those who had committed suicide.
A study of 191 patients found that ADHD-related impulsivity worsens the prognosis for adults with eating disorders, particularly those with bulimia and binge-eating disorders. The research also identified age and low self-direction as risk factors for developing an eating disorder.
OCD researchers discovered a mechanism underlying compulsive behaviors in mice, suggesting potential treatments. The study's findings could lead to novel drug development and direct stimulation techniques, including deep brain stimulation.
A new approach using brain-training computer games is being explored to improve memory and thinking in forensic psychiatry patients, who are considered among the most severely mentally ill. The games may be used with psychotherapy, medication, and other approaches to help these patients restore their competency.
Researchers found ketamine to be effective in treating treatment-resistant depression within 24 hours, with a response rate of 63.8% compared to 28% in the placebo group. The antidepressant benefits were durable after seven days, making ketamine a promising new treatment option for patients with severe and refractory forms of depression.
Researchers at NYU Langone Health found that combat veterans with PTSD exhibit abnormal brain activity in key fear and anxiety regions even at rest. The study sheds light on which areas of the brain provoke traumatic symptoms and represents a critical step toward better diagnostics and treatments for PTSD.
The Intelligent Clinician's Guide to the DSM-5 explores revisions to the Diagnostic and Statistics Manual, highlighting both strengths and weaknesses. The book provides a balanced assessment of psychiatric diagnosis and treatment, essential reading for mental health professionals navigating the post-DSM-5 era.
Researchers at NYU Langone Health discovered a connection between CB1 receptors and PTSD, finding that individuals with PTSD have lower levels of neurotransmitter anandamide. This breakthrough may lead to the development of novel evidence-based treatments for PTSD.
A new study found no increased risk of abnormal heart rhythms or death in patients taking daily doses of citalopram above 40mg, contradicting the FDA's warning. Higher dosages were associated with fewer adverse outcomes than lower dosages.
Researchers found distinct changes in gene activity and methylation patterns in blood cells of adult PTSD patients with a history of childhood abuse compared to those without. These differences may underlie different mechanisms of symptom formation in the brain.
A study published in JAMA Psychiatry found that psychopaths lack the basic neurophysiological 'hardwiring' necessary for caring about others. This is reflected in altered brain activity in response to pain and distress, with reduced activation in regions critical for empathy and increased activity in areas linked to emotion and reward.
Research examines similarities between food intake and addiction, but debates the application of the addiction model to food. A special issue in Biological Psychiatry explores the state of the field, covering neurobiological mechanisms, brain reward circuitry, and risk factors.
A pilot program called Single Fathers Due to Cancer has been launched at the University of North Carolina Health Care to provide emotional support to men facing unique challenges after losing their partner to cancer. The group aims to address feelings of profound aloneness and provide a safe space for men to share advice and feedback.
A new study published in Biological Psychiatry found that common genetic variants explain 42% of individual differences in antidepressant response, providing a significant step towards personalized treatment for depression. The research identified multiple genetic markers involved in predicting response to antidepressants.
Two genes associated with rare autism-related disorders are also jointly linked to more general forms of autism, according to a new study published in Molecular Psychiatry. The findings suggest a new genetic pathway to investigate in general autism research.
A new study reveals that men who have children at older ages are more likely to have grandchildren with autism. The research found that the risk of autism increases with the age of the grandfather, suggesting that genetic risk can accumulate over generations.
A study found that adding folate and vitamin B12 to antipsychotic medication improved negative symptoms of schizophrenia, particularly in individuals carrying specific genetic variants. The results suggest a potential new avenue for treatment, as well as the need for personalized medical approaches.
A new study published in JAMA Psychiatry found that targeted psychological interventions significantly reduced drinking behavior among high-risk teenagers. The 'Adventure Trial' intervention showed a 29% reduced risk of problem drinking and delayed risky drinking behavior over two years.
Researchers have developed a new technique to identify abnormal tau proteins associated with repetitive head injuries, potentially leading to earlier diagnosis and tracking of brain disorders. The study used PET scans to detect elevated levels of FDDNP in the brains of five retired NFL players.
The inaugural issue of Clinical Psychological Science (CPS) publishes diverse and boundary-crossing perspectives on topics such as targeted rejection, major depressive disorder, youth mentoring, and mind wandering. The journal aims to define a new way of studying clinical phenomena through innovative research.
A study published in Biological Psychiatry found that a medication called naltrexone can help women who quit smoking keep their weight off. The drug reduced weight gain in women by more than half, compared to those who took a placebo, and improved their overall success rate.
A study by Max Planck Institute of Psychiatry found that genetic variants of the FKBP5 gene can influence epigenetic alterations caused by early trauma, leading to lifelong dysregulation of stress hormones. This can result in increased risk of depression, post-traumatic stress disorder, and anxiety disorders in adulthood.
Low levels of omega-3 during pregnancy may trigger depressive episodes. Increasing fish consumption could help bring maternal omega-3 levels up to recommended levels, potentially reducing the risk of postpartum depression.
The Harvard Review of Psychiatry has partnered with Wolters Kluwer Health to expand its global reach and impact. The partnership aims to enhance digital publishing solutions and strategies, including the development of a new iPad edition and an updated website.
Dr. Peter F. Buckley received the 2012 Cancro Academic Leadership Award for his work in advancing child and adolescent training experiences through a recovery-oriented model of care. He led the rebuilding of the MCG Department of Psychiatry, developing innovative programs that focus on recovery from mental illness.
A $20 million gift from Andrew and Barbara Taylor has established the Taylor Family Institute for Innovative Psychiatric Research at Washington University. The institute aims to develop new therapies for psychiatric disorders, which currently have major limitations in effectiveness and potential side effects.
A study published in Archives of General Psychiatry found that highly hypnotizable individuals have greater activity in executive-control and salience networks, indicating a neural trait underlying hypnotizability. This advance enables scientists to better understand the mechanisms of hypnosis and its potential for clinical applications.
Scientists at the Max Planck Institute of Psychiatry found that effective signal transmission in the hippocampus requires theta-frequency impulses, generating waves that propagate through the brain. This discovery explains why we are more productive after drinking coffee or experiencing stress.
The American Academy of Child and Adolescent Psychiatry (AACAP) has released a new Practice Parameter addressing the unique challenges faced by gay, lesbian, bisexual, and gender variant youth. The parameter provides best clinical practices to combat stigma, bullying, and discrimination, as well as promote cultural competence and resea...
A study found that Somalis living in London experience more major depression and psychological disorders than those in Minneapolis. Practical support during integration is key to better mental health outcomes.
A study published in The Journal of Clinical Psychiatry found that individuals infected with the T. gondii parasite are seven times more likely to attempt suicide. The researchers also discovered that the parasite can cause inflammation in the brain, leading to changes in brain chemistry and potentially contributing to depression.
Latrepirdine, a compound initially rejected for Alzheimer's treatment, shows promise in animal models by reducing neurodegeneration-related proteins and activating autophagy. The study suggests potential benefits in treating or preventing disorders associated with high levels of alpha-synuclein.
Researchers found that genetic and environmental factors influence childhood characteristics differently across the UK, with some traits more strongly linked to genes in certain regions. The study's nature-nurture maps provide a global overview of how environment interacts with genetics.
A new study suggests that genetic variations can predict a person's response to drug treatments for nicotine addiction, with those at high-risk of heavy smoking showing the greatest response to pharmacologic therapy.
Two Johns Hopkins psychiatrists argue that the Diagnostic and Statistical Manual of Mental Disorders (DSM) needs radical change due to its current 'field guide' form, which provides checklists of symptoms but lacks underlying causes. The manual's limitations make it difficult for clinicians to direct treatment or investigate disorders.
Dr. Elizabeth Osuch has received a $100,000 grant to improve diagnosis of bipolar disorder in youth through functional brain imaging. The average misdiagnosis often lasts 6-10 years and can lead to declining patient condition if treated with antidepressants.
A new article by UCSF researchers outlines a 10-year plan to fight depression, emphasizing the need for routine access to prevention interventions. The authors suggest identifying high-risk individuals and reducing new cases of depression by half.
A study published in Archives of General Psychiatry identified a gene, MC4R, that increases weight gain in patients treated with commonly-used antipsychotic drugs. Patients who carry the recessive variant of this gene gained up to 20 pounds during a 12-week trial.
A study published in Archives of General Psychiatry reveals that psychopathy is characterized by reduced grey matter volumes in key brain areas, leading to impaired empathy and moral behavior. The findings suggest a clear behavioral difference between psychopaths and non-psychopathic offenders with anti-social personality disorder.
Researchers from Columbia University Medical Center will present on grief and major depression, exploring the complexities of complicated grief. The session also delves into the ethics of psychiatric relationships with pharmaceutical companies, highlighting the need for a balanced approach to patient care.