A US study found that adverse events affect 38% of adults undergoing surgery, with major incidents occurring in nearly half of cases. Most adverse events are preventable, emphasizing the need for ongoing improvement in patient safety.
Outsourcing adult social care services has led to worse care and increased inequalities. Experts suggest removing the profit motive would improve quality, but acknowledge it's not a standalone solution.
Research suggests that a 1% increase in green space in deprived urban areas could lead to 40% fewer preventable deaths. The study found that access to green space is poorest in the most deprived areas, with significant associations between green space and preventable deaths in England, Scotland, and Northern Ireland.
A review of qualitative evidence highlights men's unique experiences of the perinatal period, including anxiety, stress, and feelings of exclusion. Researchers emphasize the need for targeted support, education, and inclusion of fathers in parental information.
Research finds that certain combinations of long term conditions increase hospital admission risk by up to 11 times and death risk by up to 24 times. The study analyzed data from 2021-22 and identified specific quartets that are associated with heightened risks, highlighting the need for targeted planning and resource allocation.
Research found that individuals at risk of developing rheumatoid arthritis have distinct gut microbiome compositions, including an overabundance of Prevotellaceae species. This microbial signature correlates with traditional risk factors and is most pronounced in those who progress to the disease.
A pooled data analysis of 35 studies found that exercise-only interventions reduced the severity of depression and anxiety after giving birth, with a significant reduction in postpartum depression risk. The minimum threshold for achieving effects was at least 80 weekly minutes of moderate intensity exercise.
A study warns that a tightly tied waist cord of the underskirt in traditional sarees may lead to 'petticoat cancer' or Marjolin ulcer due to chronic inflammation. Doctors advise wearing loose clothing to ease pressure on the skin and prevent skin cancer.
A WHO guideline panel is under fire for lacking transparency and association with WPATH, which supports 'gender affirming' approach. The controversy raises questions about the evidence-based nature of the recommendations.
Researchers found that SGLT-2 inhibitors may simultaneously tackle kidney stones and gout flare-ups in patients with type 2 diabetes. The study suggests these medications can increase urinary volume and lower uric acid levels, reducing the concentration of stone-forming crystals.
A group of palliative medicine consultants criticize the APM's strong opposition to legalizing assisted dying, arguing it undercuts confidence in palliative care and stifles open discussion. They propose a more nuanced approach, acknowledging that end-of-life decisions should be made with trained healthcare professionals involved.
Research suggests that just one or two sessions of physical activity per week can lower the risk of cognitive decline and dementia, which may be more convenient for busy people than regular exercise. The 'weekend warrior' pattern was found to be associated with a 25% lower risk of cognitive decline compared to non-exercisers.
A large observational study found associations between cannabis use and brain structure and function changes in later life. However, genetic analysis using Mendelian randomization suggests that these associations may not be causal, with possible explanations including unmeasured variables or differences in statistical power.
Research finds that sustained engagement in regular physical activity before and after a dementia diagnosis is associated with the greatest reduction in risk of death, regardless of dementia type. Maintaining an exercise routine or starting new activities also reduces mortality risk, with higher levels associated with greater reductions.
A clinical trial shows promise in using a gene signature to tailor chemotherapy for high-risk breast cancer patients, improving disease-free survival rates. Patients classified as low risk had significantly higher rates of disease-free and overall survival compared to those at high risk.
An investigation by The BMJ found that pharmaceutical companies made an estimated £156 million in non-research payments to NHS trusts in England between 2015 and 2022. Most payments were below £10,000, but some large payments were not explained by the trusts.
An analysis of 1.7 million suicides in 26 countries found that Monday has the highest suicide risk, followed by New Year's Day. Risk patterns vary across weekends and holidays, with some countries experiencing increased risks on Saturdays or Sundays.
A middle-aged man with scurvy was treated after neglecting his diet and stopping supplements due to financial constraints. He had multiple risk factors, including obesity, previous bariatric surgery, and low-income status, which led to vitamin C deficiency.
Research finds that people with schizophrenia are at a significantly higher risk of sudden cardiac death, with a lifetime risk 4+ times higher than the general population. The study also suggests that mental health disorders can lead to shortened lifespan and increased risk of other causes of death.
A systematic review of 12 studies found that urban green spaces are associated with lower rates of heat-related ill health and death, particularly among vulnerable groups. Additionally, urban greenery is linked to better mental health and wellbeing, potentially mitigating the negative effects of high temperatures.
UK health leaders are urging the chancellor to invest in creating a smoke-free UK, citing the significant economic burden of smoking (£93 billion annually) and the potential for increased funding through a 'polluter pays' levy on tobacco manufacturers. Investing in tobacco control can also improve public finances by saving £2.37 for ev...
A large study of over 3 million pregnancies found no association between paternal metformin use and risk of congenital malformations. The findings provide reassurance for clinicians in making informed treatment decisions when selecting metformin for men with type 2 diabetes who plan to have children.
Research suggests that up to 42% of postmenopausal hormone-positive breast cancer cases may be linked to excess body fat, a proportion significantly higher than previously estimated using the widely used measure of BMI. The study found that a validated measure of body fat called CUN-BAE yielded more accurate results.
Systematic review of published evidence reveals no evidence for airborne spread of nut allergens; surface residues pose main risk. Airlines can minimize risk by cleaning surfaces, allowing pre-boarding, and providing allergen-free options.
A unique condition dubbed 'headspin hole' has been identified in breakdancers, characterized by a protruding scalp lump, hair loss, and tenderness. Repeatedly performing headspins increases the risk of developing this condition, highlighting the importance of recognizing chronic scalp conditions in breakdancers.
Researchers found that AI-powered chatbot answers on top 50 most prescribed drugs in US were difficult to read and lacked information, posing potential harm to patients. Only 54% of answers aligned with scientific consensus, highlighting the need for caution when relying on these tools.
Climate misinformation threatens public trust in science and policy, say medical experts. By adopting a multifaceted approach, the medical community can mitigate its impact and promote informed public discourse.
Experts debate whether doctors should face sanctions for protesting against climate change, with some arguing that civil disobedience can lead to positive social change. Doctors like Sarah Benn have been suspended after breaching an injunction order, but others argue that the GMC's actions erode trust in the medical profession.
An analysis of global data from 34 countries found a strong association between extreme rainfall events and increased mortality rates. The study identified locations with lower rainfall variability and scarce vegetation as having higher risks of deaths after extreme rainfall events.
The prevalence of treatment-resistant vaginal thrush has increased significantly in the UK, with a fourfold rise in fluconazole resistance between 2018 and 2021. This trend follows a shift in clinical practice, with doctors now treating on signs and symptoms rather than confirmatory lab tests.
A global analysis of new cancer drug launches between 1990 and 2022 found significant disparities in availability and timeliness, with poorer countries missing out. The gap between rich and poor nations widened over three decades, suggesting such inequities may explain poor cancer outcomes in many lower-income countries.
A study found that patients with hip fractures who wait over 4 hours for treatment in emergency care are at higher risk of death and longer hospital stays. The researchers analyzed data from a single trauma center in Scotland, where over 1 in 3 patients waited longer than the required standard time frame.
Researchers estimate that 7% of hospital patients receiving general medical care experience harmful diagnostic errors, most of which are preventable. The study suggests new approaches to surveillance and integrating AI tools into the workflow can minimize their prevalence.
A new study finds that fatal falls among older people in the US have a higher cost than firearm deaths, with an estimated average medical cost of $1,427,773,589 for fatal falls compared to $246,456,666 for firearm injuries. The researchers highlight the urgent need for preventive measures to address this growing public health challenge.
A trial published in The BMJ found that remote video consultations between patients and mental health specialists showed a small but significant reduction in symptoms of depression and anxiety. Compared to usual care, the PROVIDE model led to improvements in depressive and anxiety symptoms at six months and sustained effects at 12 months.
Eight in ten Integrated Care Boards in England have reduced or frozen discretionary funding for general practices' enhanced services, such as heart monitoring and minor surgery. Many general practices are facing financial ruin, with some forced to make staff redundant due to pressure on income.
An investigation by The BMJ raises concerns about the safety and effectiveness of donanemab, a new Alzheimer's drug approved by the US FDA. Financial ties among expert advisors have sparked doubts about the drug's reliability.
A consensus statement emphasizes the underdiagnosis and undertreatment of cardiovascular disease in women, highlighting the need for targeted interventions. The statement recommends the establishment of women's heart champions and hubs to improve diagnosis and treatment outcomes.
The global prevalence of myopia is projected to exceed 740 million cases by 2050, with females, East Asians, and those in urban areas showing higher rates. The condition's impact on children and teens is expected to be significant, with low and middle-income countries predicted to have a higher prevalence than high-income countries.
Bottled water's environmental impact and health risks are alarming, with 2 billion people relying on it due to limited access to safe drinking water. Microplastics, phthalates, and BPA have been linked to various health issues, while plastic waste contributes to greenhouse gas emissions.
Researchers found that four triptans - eletriptan, rizatriptan, sumatriptan, and zolmitriptan - were more effective than newer migraine drugs in relieving pain. The study suggests that access to the most effective triptans should be promoted globally.
A systematic review of studies on antiseizure drugs in men with epilepsy suggests that there is no clear evidence of a detrimental impact on offspring outcomes. While some isolated harmful side effects were found, they were not replicated in other investigations. The review casts doubt on the stance taken by the UK drugs regulator and ...
A fifth of UK GPs are using generative AI in clinical practice, with most using tools for administrative tasks or to support clinical reasoning. However, experts caution against the limitations and risks of these tools, including inaccuracies, biases, and potential harm to patient privacy.
Researchers found that laughter exercise improved dry eye disease symptoms and clinical signs, such as ocular surface discomfort and tear break-up time, comparable to eye drops. Laughter therapy also showed benefits in mental health scores.
An investigation by The BMJ found that at least 11 out of 17 UK government nutrition advisory panel members have conflicts of interest with food firms. This has led to concerns that these ties may undermine the committee's independence and expertise, particularly in addressing rising obesity levels and food-related ill health.
A new study published in The BMJ found that shorter-course radiation therapy is safer and more convenient for breast cancer patients than conventional schedules. Moderate hypofractionation reduced the risk of acute radiation dermatitis by 46% compared to conventional fractionation, while also improving cosmesis and quality of life.
Across England, nearly half of patients struggle to get appointments with specialist teams for weight loss support and care. Bariatric surgery services are also severely limited, affecting over one in five local health areas. Experts warn that without radical action, obesity prevalence and costs will continue to rise.
A study published by The BMJ found that one dose of modified vaccinia Ankara-Bavarian Nordic (MVA-BN) smallpox vaccine is moderately effective in preventing mpox infection. The vaccine showed an estimated 58% vaccine effectiveness against mpox, suggesting it should be made available to communities at risk.
Research suggests statin therapy is cost-effective and beneficial for most over-70s individuals, with increased quality-adjusted life years (QALYs) and reduced healthcare costs. Lifetime use of standard statins increased QALYs by 0.24–0.70, while higher intensity therapy increased QALYs by a further 0.04–0.13.
A study of 32,409 participants found a strong association between abdominal fat and chronic musculoskeletal pain, especially in women. Reducing visceral adipose tissue and subcutaneous adipose tissue may be key to managing chronic pain in multiple body sites.