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Columbia University's Mailman School of Public Health


Trauma-induced changes to genes may lead to PTSD

Researchers at Columbia University's Mailman School of Public Health found that traumatic experiences alter genes involved in stress response and immune system, leading to post-traumatic stress disorder (PTSD). The study identified six to seven times more unmethylated genes in individuals with PTSD, most related to the immune system.

SourceColumbia University's Mailman School of Public Health·JournalProceedings of the National Academy of Sciences·DateMay 4, 2010

Lesbian, gay, bisexual individuals risk psychiatric disorders from discriminatory policies

A study by Columbia University's Mailman School of Public Health found that LGB individuals living in states with same-sex marriage bans experienced significant increases in mood disorders, generalized anxiety disorder, and alcohol use disorders. The prevalence of any psychiatric disorder also increased among heterosexual respondents, ...

SourceColumbia University's Mailman School of Public Health·JournalAmerican Journal of Public Health·DateMar 2, 2010

Combined drug therapy to treat TB and HIV significantly improves survival

A new study published in the New England Journal of Medicine found that initiating antiretroviral therapy during tuberculosis treatment significantly reduces mortality rates for co-infected patients. The trial, which involved 642 patients, showed a 56% reduction in mortality rates compared to those who received sequential therapy.

SourceColumbia University's Mailman School of Public Health·JournalNew England Journal of Medicine·DateFeb 25, 2010

Exposure to tobacco smoke in childhood home associated with early emphysema in adulthood

Researchers at Columbia University's Mailman School of Public Health found that children exposed to tobacco smoke at home were more likely to develop early emphysema in adulthood. The study used CT scans to examine the association between childhood exposure and lung damage, with participants who lived with multiple smokers showing high...

SourceColumbia University's Mailman School of Public Health·JournalAmerican Journal of Epidemiology·DateDec 28, 2009

Exposures to metals and diesel emissions in air linked to respiratory symptoms in children

A new study found that exposure to airborne metals like nickel and vanadium, as well as diesel exhaust particles, are associated with respiratory symptoms in young children. The study controlled for other risk factors and suggests improved regulatory action is needed to protect urban children.

SourceColumbia University's Mailman School of Public Health·JournalAmerican Journal of Respiratory and Critical Care Medicine·DateNov 23, 2009

Mandatory alcohol testing for truck and bus drivers reduces alcohol involvement in fatal crashes

A study of nearly 70,000 motor carrier drivers and over 83,000 non-motor-carrier drivers found that mandatory alcohol testing programs reduced alcohol involvement in fatal crashes by 23%. The study's findings suggest that implementation of such programs can improve safety records in the US and other countries.

SourceColumbia University's Mailman School of Public Health·JournalAmerican Journal of Epidemiology·DateSep 11, 2009

Antibodies to strep throat bacteria linked to obsessive compulsive disorder in mice

Researchers at Columbia University's Mailman School of Public Health have found a link between antibodies to strep throat bacteria and the development of obsessive-compulsive disorder in mice. The study suggests that an inappropriate immune response to the bacteria may trigger psychiatric symptoms, providing new insights into identifyi...

Got ear plugs? You may want to sport them on the subway and other mass transit, researchers say

Researchers found Metropolitan Transit Authority (MTA) subways had the highest average noise levels in New York City, with levels high enough to increase the risk of noise-induced hearing loss. The study highlights the need for increased transit infrastructure maintenance and personal protection measures to reduce noise exposure.

SourceColumbia University's Mailman School of Public Health·JournalAmerican Journal of Public Health·DateJun 18, 2009

NIH invests $46 million in regional consortium for emerging infectious disease research

The Northeast Biodefense Center, a regional collaboration of major centers, will conduct interdisciplinary research on diagnostics, therapeutics, and vaccines to address emerging infectious diseases. The center has made significant contributions to global health, including the development of diagnostics for SARS and pandemic influenza.

Differences in neighborhood food environment may contribute to disparities in obesity

A study by Columbia University's Mailman School of Public Health found that a higher density of 'healthy' food outlets is associated with lower BMI and obesity rates in New York City. The study surveyed over 13,000 adults and found that unhealthy food stores were not significantly linked to higher BMI or obesity.

SourceColumbia University's Mailman School of Public Health·JournalEnvironmental Health Perspectives·DateMar 19, 2009

Work stress associated with adverse mental and physical health outcomes in police officers

A study by Columbia University's Mailman School of Public Health found that work stress among urban police officers is significantly associated with adverse mental and physical health outcomes, including depression, anxiety, and intimate partner abuse. The study identified five major categories of stressors, including exposure to criti...

Study analyzes 2006 California heat wave's substantial effect on morbidity

The 2006 California heat wave had a significant impact on morbidity, with dramatic increases in emergency department visits and hospitalizations reported. The study found that older residents and children were particularly vulnerable to heat-related illnesses, highlighting the need for targeted public education and preparedness efforts.

SourceColumbia University's Mailman School of Public Health·JournalEnvironmental Health Perspectives·DateFeb 25, 2009

Research identifies risk factors that affected World Trade Center evacuation

A study by Columbia University's Mailman School of Public Health identified key risk factors that delayed or prolonged the evacuation from the World Trade Center Towers on September 11. The researchers found that lack of awareness and experience, as well as personal concerns and poor footwear, contributed to time delays.

SourceColumbia University's Mailman School of Public Health·JournalDisaster Medicine and Public Health Preparedness·DateJan 26, 2009

Outdoor alcohol advertising and problem drinking among African-American women in NYC

A study of 139 African-American women in Central Harlem found a significant link between exposure to alcohol advertisements and problem drinking behavior. The researchers also discovered that family history of alcoholism played a role in problem drinking, with advertising continuing to have an impact even after controlling for this fac...

SourceColumbia University's Mailman School of Public Health·JournalAmerican Journal of Public Health·DateJan 12, 2009

Trends in sexual behaviors similar for teens who take few health risk and those who take many

A study by Columbia University's Mailman School of Public Health found that teen sexual risk behaviors are similar among youth with few and those with many non-sexual health risks. Despite differences in overall health risk levels, trends in sexual behavior were remarkably consistent across both groups.

SourceColumbia University's Mailman School of Public Health·JournalJournal of Adolescent Health·DateDec 19, 2008

First evidence that prenatal exposure to famine may lead to persistent epigenetic changes

A study found that prenatal exposure to famine can cause epigenetic changes in humans that persist throughout life, increasing the risk of adverse health outcomes. Children conceived during the Dutch Hunger Winter had less DNA methylation of the IGF2 gene than their unexposed siblings.

SourceColumbia University's Mailman School of Public Health·JournalProceedings of the National Academy of Sciences·DateOct 30, 2008

Strong association found between prevalence of low white blood count and women of African descent

Researchers at Columbia University's Mailman School of Public Health found a strong association between neutropenia, or low white blood count, and women of African descent. This association may affect disparities in disease treatment and outcomes for cancer therapy, particularly among those with breast and colon cancer.

SourceColumbia University's Mailman School of Public Health·JournalBritish Journal of Haematology·DateSep 19, 2008

Study firmly shows no connection between measles, mumps, rubella (MMR) vaccine and autism

A study published in Public Library of Science found no association between the MMR vaccine and the onset of autism or gastrointestinal symptoms in children. The study analyzed bowel tissues from 25 children with autism and GI disturbances, as well as 13 controls, and found no presence of measles virus RNA in either group.

Early cessation of breastfeeding by HIV+ women in poor countries and child survival

Researchers found that early cessation or continued breastfeeding by HIV-infected women in low-resource settings does not significantly affect child survival. Infants who were weaned abruptly had higher death rates than those whose mothers continued breast-feeding, while formula-fed infants missed out on protective antibodies.

SourceColumbia University's Mailman School of Public Health·JournalNew England Journal of Medicine·DateJul 24, 2008