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DOE/Joint Genome Institute


A new cost-effective genome assembly process

A new cost-effective genome assembly process has been developed by a collaboration between DOE/JGI, Pacific Biosciences, and the University of Washington. The HGAP method produces final assemblies with >99.999% accuracy using single molecule real-time DNA sequencing, eliminating the need for circular consensus sequencing.

SourceDOE/Joint Genome Institute·JournalNature Methods·DateMay 5, 2013

Same fungus, different strains

Researchers analyzed genome sequences of two Aspergillus niger strains to improve biofuel production. They found unique genes in each strain that contribute to their characteristics, including high citric acid yields and efficient enzyme production.

SourceDOE/Joint Genome Institute·JournalGenome Research·DateMay 13, 2011

Breaking biomass better

The DOE Joint Genome Institute has sequenced and published the genomes of two wood-decaying fungi, advancing biofuels prospects. Studying the genome of Schizophyllum commune reveals a diverse set of enzymes involved in plant biomass degradation, offering opportunities for efficient biomass conversion into biofuel.

SourceDOE/Joint Genome Institute·JournalNature Biotechnology·DateJul 12, 2010

New genomic model defines microbes by diet -- provides tool for tracking environmental change

A new genomic model defines microorganisms by their dietary habits, providing a tool for tracking environmental changes. The researchers analyzed the genomes of two bacteria with distinct lifestyles and developed a predictive model that successfully identified the habitats of dozens of bacterial samples.

SourceDOE/Joint Genome Institute·JournalProceedings of the National Academy of Sciences·DateSep 7, 2009