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ETH Zurich


Ironing out oxidative stress

A new study by ETH Zurich researchers has identified a critical link between oxidative stress and the immune system's ability to fight off viruses. Vitamin E was shown to be effective in protecting T cells from cell death caused by oxidative stress, a breakthrough that could have implications for treating chronic infections.

SourceETH Zurich·JournalJournal of Experimental Medicine·DateApr 8, 2015

From tobacco to cyberwood

Researchers at ETH Zurich have developed a highly sensitive temperature sensor called cyberwood, which mimics the properties of temperature-sensitive plants. By incorporating plant cells and pectin molecules, the material responds to small temperature fluctuations with large changes in conductivity.

SourceETH Zurich·JournalProceedings of the National Academy of Sciences·DateMar 30, 2015

Climate change does not cause extreme winters

Scientists at ETH Zurich and the California Institute of Technology have shown that global warming reduces temperature variability, leading to fewer cold snaps and less fluctuation in mid-latitude temperatures. This contradicts the hypothesis that Arctic amplification contributes to extreme winter events in lower latitudes.

SourceETH Zurich·JournalJournal of Climate·DateMar 27, 2015

From blue pill to blue light

Researchers at ETH Zurich have developed a novel biotechnological solution to treat erectile dysfunction by triggering reliable erections with gene therapy and blue light exposure. The system works similarly across all mammals, including humans, and is expected to have few side effects.

SourceETH Zurich·JournalAngewandte Chemie International Edition·DateMar 23, 2015

How rain is dependent on soil moisture

Researchers at ETH Zurich found that rain falls most frequently in areas with lower soil moisture, which warms air and allows water vapor to rise higher. High soil moisture, on the other hand, can lead to more evaporation and precipitation, but the relationship is complex and still not fully understood.

SourceETH Zurich·JournalNature Communications·DateMar 5, 2015

A taxi ride to starch granules

The discovery of Protein Targeting to Starch (PTST) reveals the crucial role of a molecule in transporting Granular Bound Starch Synthase (GBSS) to starch granules, necessary for normal amylose synthesis. The research found that PTST is essential for GBSS stability and function.

SourceETH Zurich·JournalPLOS Biology·DateFeb 26, 2015

Voltage tester for beating cardiac cells

Electrical engineers at ETH Zurich and biologists from the University of Bern have developed a new method to record the activity of moving cells, including beating cardiac muscle cells. The new method combines the patch-clamp technique with an atomic force microscope, allowing for longer measurements and automation.

SourceETH Zurich·JournalNano Letters·DateFeb 17, 2015

Data-storage for eternity

Researchers have developed a new method to store large volumes of data using DNA and silica, which can potentially survive for over a million years. The technique uses an algorithm to correct errors and encases the information-bearing segments of DNA in silica, providing a robust storage solution.

SourceETH Zurich·JournalAngewandte Chemie International Edition·DateFeb 12, 2015

Birth of a star quartet

An international team of astrophysicists has witnessed the formation of a quadruple star system, consisting of a young star and three gas clouds that will develop into stars in 40,000 years. The system is unstable and prone to interference due to its multiple members.

SourceETH Zurich·JournalNature·DateFeb 11, 2015

Inhospitable climate fosters gold ore formation

The gold deposits in the Witwatersrand Basin are thought to have formed through a process involving volcanic rain, anoxic rivers, and ancient life forms. This theory reconciles previous debates between placer gold and hydrothermal hypothesis theories.

SourceETH Zurich·JournalNature Geoscience·DateFeb 4, 2015

Demystifying nanocrystal solar cells

Researchers at ETH Zurich developed a physical model explaining electron transport in nanocrystal solar cells, which could lead to improved efficiency. The model reveals that nanocrystal size can be controlled to optimize absorption of sunlight, enabling the creation of flexible and thin solar cells with higher performance.

SourceETH Zurich·JournalNature Communications·DateJan 28, 2015

The 2 faces of Mars

A massive celestial object impacted Mars, generating a magma ocean that solidified into the mountainous highlands of the southern hemisphere. This event, occurring around 4-15 million years after Mars' formation, is believed to have triggered volcanic activity and changed the planet's magnetic field.

SourceETH Zurich·JournalGeophysical Research Letters·DateJan 28, 2015

Cellulose with Braille for cells

Scientists at ETH Zurich develop a method to produce pre-structured cellulose materials with three-dimensional micro-structures, enhancing biocompatibility. This leads to reduced inflammation and rejection reactions when using artificial implants.

SourceETH Zurich·JournalACS Nano·DateJan 19, 2015

A voyage from the Earth's crust to its mantle and back again

Researchers analyzed mid-ocean ridge basalts to understand the uranium isotope cycle, revealing a 'fingerprint' of the element in oceanic crust. The study suggests that uranium has been transported from the surface to the deep mantle through subduction, providing insights into Earth's evolution over billions of years.

SourceETH Zurich·JournalNature·DateJan 19, 2015

Damaged DNA amplified

Researchers at ETH Zurich have developed a method to amplify gene samples containing damaged DNA adducts, which are common in cancer. This breakthrough could enable the analysis of molecular mechanisms involved in cancer initiation and risk factors.

SourceETH Zurich·JournalJournal of the American Chemical Society·DateJan 15, 2015

Glass for battery electrodes

Researchers at ETH Zurich have discovered a new glass material that can store more energy than traditional lithium-ion batteries. The vanadate-borate glass exhibits improved charging capacity and stability, paving the way for more efficient electric vehicles and longer-lasting portable electronics.

SourceETH Zurich·JournalScientific Reports·DateJan 13, 2015

Bioplastic -- greener than ever

A new method to produce lactic acid from glycerol, a waste feedstock, has been introduced, reducing CO2 emission by 30% compared to conventional fermentation. The process also lowers production costs, increasing the potential profit by 17-fold.

SourceETH Zurich·JournalEnergy & Environmental Science·DateDec 3, 2014

How early trauma influences behavior

Research suggests that early-life stress can have positive effects on behavior, such as improved flexibility and goal-oriented behavior, which can be passed down through generations via molecular pathways. This study reveals the beneficial impact of moderate stress in childhood, leading to better coping strategies in adulthood.

SourceETH Zurich·JournalNature Communications·DateDec 1, 2014

A jettisoned black hole?

Researchers have identified an enigmatic object named SDSS1133, which could be a recoiling black hole ejected from its parent galaxy. The discovery, made using high-precision equipment and observations with the Hubble Space Telescope, presents a unique opportunity to study gravitational waves and their detection.

SourceETH Zurich·JournalMonthly Notices of the Royal Astronomical Society·DateNov 19, 2014

Shaking the topological cocktail of success

Researchers at ETH Zurich create an artificial graphene system that breaks time-reversal symmetry using laser beams and ultracold atoms. This setup enables the testing of the topological Haldane model, a concept first proposed in 1988, and paves the way for new electronic applications.

SourceETH Zurich·JournalNature·DateNov 12, 2014

Understanding natural compounds

Researchers develop computer-based method to predict mechanism of action of natural substances, identifying potential target structures for 210,000 compounds. The software breaks down molecules into smaller fragments, discovering essential parts for the mechanism of action, which can be used to design less complex and easier-to-synthes...

SourceETH Zurich·JournalNature Chemistry·DateNov 12, 2014

Controlling genes with your thoughts

Researchers at ETH Zurich have developed a novel gene regulation method that enables thought-specific brainwaves to control the conversion of genes into proteins. The system uses EEG headsets to transmit brainwaves wirelessly to an implant, which regulates gene expression through light-sensitive optogenetic modules.

SourceETH Zurich·JournalNature Communications·DateNov 11, 2014

Groundwater warming up in synch

Researchers found that groundwater temperatures have warmed significantly over the past forty years, echoing global warming trends. The warming is attributed to climate change and has been observed in groundwater close to the surface, with a certain time lag.

SourceETH Zurich·JournalHydrology and Earth System Sciences·DateNov 11, 2014

New antibiotic in mushroom that grows on horse dung

Researchers at ETH Zurich have discovered a new agent in fungi that kills bacteria, known as copsin, which has the same effect as traditional antibiotics but belongs to a different class of biochemical substances. The substance was found in the common inky cap mushroom Coprinopsis cinerea and is responsible for its antibiotic effect.

SourceETH Zurich·JournalJournal of Biological Chemistry·DateNov 7, 2014

No quick fix for global warming

A new study published in PNAS suggests that eliminating short-lived climate pollutants (SLCF) has a minor effect on slowing down global warming. The research found that these gases have a measurable impact but are short-lived and quickly disappear from the atmosphere, making them less effective in mitigating climate change.

SourceETH Zurich·JournalProceedings of the National Academy of Sciences·DateNov 3, 2014

Precise and programmable biological circuits

Bio-engineers at ETH Zurich have created a biological circuit that controls sensor components using internal timers, enabling precise signal transmission. This breakthrough could lead to reprogramming cancer cells and creating complex bio-computers to detect and kill cancer cells.

SourceETH Zurich·JournalNature Chemical Biology·DateOct 23, 2014

Flu viruses disguised as waste

Researchers discovered flu virus exploits aggresome, a cellular waste bundle, to release genetic material. The process takes 20-30 minutes and is gradual, with the virus tricking the waste pickup and disposal system.

SourceETH Zurich·JournalScience·DateOct 23, 2014

Extremely high-resolution magnetic resonance imaging

The researchers have developed a novel measurement technique for MRI signals using a diamond sensor chip, detecting the signal from a single hydrogen atom and achieving an accuracy of better than one angstrom. This breakthrough brings them closer to imaging at the level of single molecules, with potential applications in structural bio...

SourceETH Zurich·JournalScience·DateOct 21, 2014

Emergency aid for overdoses

A new agent has been developed to treat overdoses using peritoneal dialysis, which can extract up to a hundred times more toxins from the body than conventional alternatives. This method is especially effective for treating serious liver disease, including cases involving ammonia accumulation in the blood.

SourceETH Zurich·JournalScience Translational Medicine·DateOct 17, 2014

Making sure antibiotics work as they should

Researchers at ETH Zurich have studied the molecular structure of mitoribosomes, revealing new details about how proteins are synthesized. The findings will help design antibiotics that target only bacterial ribosomes, improving their effectiveness in treating human diseases.

SourceETH Zurich·JournalNature·DateOct 8, 2014

Smartphone understands hand gestures

A new algorithm developed by ETH Zurich researchers enables smartphones to understand hand gestures, allowing users to control their devices with ease. The program recognizes six different gestures and executes corresponding commands, such as switching between browser tabs or scrolling pages.

Solar explosions inside a computer

Researchers have developed a model that uses self-organised criticality and fluid dynamics to predict the occurrence of solar flares. The model has shown to be consistent with observations in a quantitative sense, enabling scientists to better understand and prepare for these powerful events.

SourceETH Zurich·JournalNature Communications·DateSep 24, 2014

Withdrawal from the evolutionary race

Researchers found that certain individuals with HIV are more tolerant of the virus than others, with factors including age and HLA-B gene variants playing a role. The study suggests that tolerance-based treatments could be an alternative to traditional resistance-based strategies.

SourceETH Zurich·JournalPLOS Biology·DateSep 18, 2014

Measuring modified protein structures

Researchers have developed a new method to measure structurally modified proteins in complex biological samples, enabling the analysis of thousands of proteins. The method uses a combination of digestion enzymes and Selected Reaction Monitoring to quantify protein quantities and determine structural changes.

SourceETH Zurich·JournalNature Biotechnology·DateSep 14, 2014

How salt causes buildings to crumble

Researchers at ETH Zurich conduct experiment to test salt's effect on building materials. They find supersaturation of salt solution is key factor in damage, with temperature playing a role. The study's findings could help conservators and restorers predict and mitigate salt damage.

SourceETH Zurich·JournalNature Communications·DateSep 11, 2014

New defense mechanism against viruses discovered

Researchers from ETH Zurich have discovered a new form of innate immune defence against certain RNA viruses, including those causing hepatitis C, yellow fever, and dengue fever. The NMD system, which is a quality control mechanism in cells, also serves as a general virus restriction mechanism in plants.

SourceETH Zurich·JournalCell Host & Microbe·DateSep 11, 2014

Mantle plumes crack continents

Mantle plumes may be responsible for breaking up continents, according to a new study. The researchers used high-resolution computer simulations to demonstrate how the interaction between a plume and a plate under tensile stress can lead to continental breakup, forming rift systems and creating volcanoes.

SourceETH Zurich·JournalNature·DateSep 4, 2014

Nanoscale assembly line

Researchers at ETH Zurich have developed a nanoscale assembly line that uses mobile assembly carriers and biological motors to assemble complex substances. The system, which is three times thinner than a human hair, enables the selective modification of organic molecules and the assembly of nanotechnological components.

SourceETH Zurich·JournalLab on a Chip·DateAug 28, 2014

Why global warming is taking a break

Researchers find that El Niño and La Niña events, as well as weakened solar activity and aerosol concentrations, contributed to the recent slowdown in global warming. The study suggests that short-term climate fluctuations can be explained by natural factors without contradicting long-term warming trends.

SourceETH Zurich·JournalNature Geoscience·DateAug 19, 2014

The economy of bitcoins

Researchers found that internet activity significantly influences Bitcoin's value, with correlations between price developments, new user growth, and online searches. The study also identified two positive feedback loops and a negative feedback loop, highlighting the complex dynamics of the Bitcoin economy.

SourceETH Zurich·JournalInterface·DateAug 7, 2014

Curing arthritis in mice

A new fusion molecule has been developed to treat rheumatoid arthritis in mice, with promising results showing the animals' symptoms disappear completely. The therapy targets specific immune messengers and reduces side effects by concentrating the active substance at the site of disease, offering a potential long-term cure.

SourceETH Zurich·JournalProceedings of the National Academy of Sciences·DateAug 6, 2014

New approach for tuberculosis drugs

Researchers at ETH Zurich have developed a new approach for tuberculosis drugs, inspired by the bacteria-derived antibiotic pyridomycin. The new molecule is more stable and easier to produce synthetically, offering a potential solution to multidrug-resistant strains.

SourceETH Zurich·JournalNature Chemical Biology·DateJul 2, 2014

Body odor reveals malarial infection

Researchers found that malaria parasites manipulate host body odor to make infected individuals more attractive to hungry mosquitoes. Even after symptoms have subsided, the scent of infected mice remained elevated for life, suggesting a lifelong impact on the disease.

SourceETH Zurich·JournalProceedings of the National Academy of Sciences·DateJun 30, 2014

A versatile joystick for animation artists

A Swiss research team created an innovative joystick for animation artists, consisting of modular building blocks that can be assembled into any virtual character shape. The device features integrated sensors that track joint movements, enabling smooth character articulation.

Invisibility cloak for immune cells

Scientists at ETH Zurich have identified a mechanism that protects immune cells from natural killer cells. Type I interferon receptors play a crucial role in this process, and its absence can lead to the elimination of healthy immune cells. This discovery may have implications for understanding autoimmune diseases.

SourceETH Zurich·JournalImmunity·DateJun 25, 2014

Straw albedo mitigates extreme heat

Researchers at ETH Zurich found that unploughed stubble reflects more solar radiation than tilled surfaces, resulting in a 50% higher level of reflection and a significant effect on extreme heat. No-till farming can reduce local temperatures by up to 2°C on hot days.

SourceETH Zurich·JournalProceedings of the National Academy of Sciences·DateJun 23, 2014

Better catalysts for the petrochemical industry

Researchers from ETH Zurich have identified a new class of zeolite catalysts that can withstand the formation of hydrocarbon deposits, which clog pores and block active sites. The key to their improved performance lies in the internal structure of the catalysts, with well-connected nano-sized channels and numerous openings.

SourceETH Zurich·JournalNature Communications·DateMay 28, 2014