Researchers at McMaster University have identified post-biotics, by-products of bacteria, that lower blood glucose and allow insulin to work better. This discovery could lead to new therapies for obesity-related diabetes, as more than half of Canadians are overweight or obese.
Researchers at McMaster University found that imbalances in gut microbes lead to intestinal leakage, triggering inflammation, impaired immune function, and reduced lifespan. The study suggests targeting age-associated inflammation may improve immune health and reduce the risk of chronic conditions.
A study by researchers at McMaster University found that low-dose penicillin in early life can induce long-term behavioral changes, including elevated aggression and lower anxiety levels. Introducing beneficial bacteria may help prevent these effects.
A new study by McMaster University suggests that cannabis use is associated with an 82% increased risk of continuing opioid use among women in methadone treatment. The research found that nearly 60% of men and 44% of women using methadone also use cannabis.
A new study reveals that there are over 79 rare genetic forms of obesity associated with various clinical features, far outnumbering previous estimates. The research highlights the need for national and international collaborations to identify the genes responsible for these syndromes.
A new study published in Scientific Reports found that survivors of childhood brain tumors have more fat tissue overall, especially around the abdomen, compared to healthy children. This increased body fat may program their future risk of cardiovascular disease and Type 2 diabetes, impacting their outcomes.
A large international study found that rivaroxaban is more effective and safer than aspirin at preventing recurrent blood clots. The study showed that patients taking rivaroxaban had significantly lower rates of recurrent clots compared to those taking aspirin.
Researchers identified a genetic disorder, ARVC, caused by mutations in the CDH2 gene, leading to cardiac arrest and sudden death. The discovery provides a new understanding of the disease and paves the way for preventative interventions and genetic counseling.
McMaster researchers have discovered a new combination therapy that effectively treats the world's worst infectious diseases, including superbugs resistant to all known antibiotics. The treatment targets Gram-negative bacteria with an intrinsically impenetrable outer shell, making infections deadly in hospital settings.
A McMaster University study found that intestinal bacteria impact both intestinal and behavioral symptoms in IBS patients, potentially leading to new microbiota-directed therapies. The study also suggests a possible link between gut bacteria and other brain disorders such as autism, Parkinson's disease, and multiple sclerosis.
A study by McMaster University researchers found that wearing a police uniform creates bias towards individuals perceived as having low social status. The researchers observed slower reaction times when participants were distracted by images of people wearing hoodies while wearing the uniform.
A McMaster University study reveals that short, intense stair climbing can significantly improve cardiorespiratory fitness and reduce the risk of heart disease. The research also highlights interval training as a convenient way to incorporate exercise into daily life.
A consumer EEG device is generating valuable data for neuroscience research, revealing new information on what happens to our thinking processes as we age. The device's large-scale data collection has enabled scientists to study the brain in the real world, shedding light on sex differences and cognitive functions.
Researchers at McMaster University have demonstrated that early in-bed cycling sessions can safely start with critically ill ICU patients. The TryCYCLE study shows cycling within four days of mechanical ventilation can help these patients walk farther upon hospital discharge.
A systematic review of public health guidelines found that recommendations for limiting sugar intake are based on low-to-very-low quality evidence. The researchers suggest that while limiting sugar intake is advisable, the degree and alternatives remain unclear.
Genetic analysis of ancient DNA reveals that the evolution of smallpox occurred far more recently than previously believed, with all available strains having an ancestor no older than 1580. Researchers found two circulating strains of the virus, variola major and minor, after English physician Edward Jenner developed a vaccine in 1796.
Researchers discovered a bacterium in Lechuguilla Cave that resists 18 different antibiotics, including 'drugs of last resort'. This finding suggests evolutionary pressure has driven resistance for millions of years, not just since antibiotics were introduced.
Researchers have found overwhelming evidence of malaria's existence in ancient Rome dating back to the Roman Empire. The study analyzed human remains from three Italian cemeteries and confirmed the presence of Plasmodium falciparum, a parasite responsible for nearly 450,000 deaths worldwide each year.
A new study from McMaster University finds that chronic conditions like arthritis, depression, and diabetes can lead to disability and reduced social participation in middle-aged adults. The research highlights the importance of targeting treatment strategies for patients and developing preventative health plans.
Researchers found a genetic alteration in the DIXDC1 gene that affects brain cell growth and communication in individuals with autism spectrum disorders. This discovery holds promise for identifying new medications targeting core symptoms of autism.
Researchers found a combination of immunotherapy options improves overall survival and lowers the risk of life-threatening events in late-stage melanoma patients. PD-1 inhibitors were associated with the lowest risk of life-threatening events, making them a promising first-line therapy option.
A large international study led by McMaster University researchers found that low-intensity ultrasound treatment after surgical repair of a bone fracture has no effect on recovery time or quality of life. The study involved 501 patients and showed that using either an active or placebo device did not improve outcomes.
A large international study of almost 31,500 patients showed that using older blood for transfusions does not increase the risk of death. The research, published in the New England Journal of Medicine, provides strong evidence that stored blood can be safely used to ensure a stable blood supply.
A longitudinal study of extreme preemies born between 1977 and 1982 found that they are four times more likely to develop dysglycemia than normal birth weight peers. By their early 30s, 26% of ELBW babies have abnormal blood glucose levels.
Researchers found that certain gut bacteria, such as Pseudomonas aeruginosa, metabolize gluten differently than beneficial bacteria like Lactobacillus. This variation can either stimulate inflammation in individuals with genetic risk or detoxify gluten, potentially influencing celiac disease development.
Researchers at McMaster University have developed a new method to isolate pure semiconducting carbon nanotubes from impurities. This breakthrough resolves a long-standing challenge in harnessing the potential of carbon nanotubes in electronics and computing.
A recent study published in Annals of Internal Medicine has found that flu nasal sprays provide similar protection against influenza as standard flu shots. The study, conducted over three years in a Hutterite colony, shows that the nose spray had a similar effect to the standard flu shot in protecting both children and community members.
The study compared seven ventilation strategies and found that LISA, a non-invasive ventilation strategy, was the most effective in preventing death and/or chronic lung disease in preterm infants. On average, LISA resulted in 164 fewer preterm babies dying or having long-term breathing problems.
McMaster engineers are working with Aevitas to create cost-effective and faster treatment solutions for biocides in industrial wastewater. The partnership aims to reduce biocide usage and protect the environment, with a goal of improving treated wastewater quality.
Researchers at McMaster University have developed a novel vaccine candidate, BD584, which shows promise in reducing chlamydial shedding and hydrosalpinx by 95% and 87.5%, respectively. The vaccine has the potential to be widely protective against all Chlamydia trachomatis strains, including those causing trachoma.
Scientists at McMaster University have discovered a clear way to measure past changes in vitamin D deficiency, which affects over 1 billion people worldwide. They analyzed the microscopic structure of ancient teeth to reveal anomalies formed in dentin layers during periods of low sun exposure.
A global study confirms that 90% of strokes can be prevented by modifying 10 modifiable risk factors, including hypertension, physical activity, and diet. The ranking of these factors varies by region, emphasizing the need for tailored strategies to reduce stroke risk.
A new study from McMaster University found that lifting lighter weights many times can be as efficient as lifting heavy weights for fewer repetitions in building muscle and strength. Researchers analyzed muscle and blood samples and found gains in muscle mass and fibre size were virtually identical between the two groups.
A systematic review of 30 observational studies found that disruption of sensory nerves in the axilla during armpit lymph node surgery is associated with chronic pain. Younger age and radiation therapy are also risk factors for developing chronic post-surgical pain.
Research published in Pediatrics found that children who engage in thumb-sucking or nail-biting habits have a lower risk of developing allergic sensitization. The study, which followed over 1,000 New Zealand children from age 5 to 32, also found no association between these habits and the development of asthma or hay fever.
A new platform harnesses DNA as the engine of a microscopic nanomachine, detecting trace amounts of substances such as viruses, bacteria, and metals. The technology uses selectively triggered DNA molecules to create a signal, enabling ultra-sensitive detection and potential clinical testing.
Research from McMaster University found that children who watched unhealthy food and beverage ads consumed significantly more calories than those who did not watch ads. The study suggests that targeted advertising of unhealthy foods can have a lasting impact on children's dietary preferences.
The world's peat bogs, once waterlogged repositories of dead moss, are being converted into fuel-packed fire hazards that can burn for months and generate deadly smoke. Research shows that peat mining, drainage, and global warming have made a growing number of the world's bogs dry and vulnerable to fire.
Researchers at McMaster University found that physical activity can retain, repair, and regenerate damaged muscle in the elderly. After eight weeks of exercise, old mice were able to repair and rebuild muscle more quickly following injury compared to non-exercise groups.
Studies find individuals with ADHD or obesity prefer smaller immediate rewards over larger future rewards, leading to potential new treatments for these conditions. The research suggests a connection between the inability to delay gratification and addictive disorders.
A study published in Scientific Reports found that almost all teenagers engage in risky listening habits, leading to persistent tinnitus and heightened sensitivity to loud sounds. The researchers warn of a major public health challenge as the prevalence of hearing damage is expected to increase.
A dietary supplement containing 30 natural ingredients has shown promise in preventing and reversing massive brain cell loss in mice. The supplement was found to completely eliminate severe brain cell loss and abolish cognitive decline in mice with widespread brain damage.
PhD candidate Gwendolyn Eadie has developed a method to estimate the mass of the Milky Way using globular cluster velocities. This approach predicts the mass contained within any distance from the center of the galaxy, providing new insights into the dark matter component.
Researchers at CanChild Centre developed an autism classification system that defines levels of social communications ability among children with autism spectrum disorder. The new system, called the Autism Classification System of Functioning: Social Communication, provides a standardized and simplified way for clinicians to talk about...
Researchers found that a 20-second pitch clock limit would cause seven percent more arm fatigue in pitchers. This increase in fatigue can strain the ulnar collateral ligament, leading to greater risk of injury, including Tommy John surgery.
A study published in PLOS ONE found a link between videogame addiction and health issues such as sleep deprivation, obesity and elevated blood pressure in children and teens. The research suggests that excessive gaming can lead to negative impacts on physical and mental health.
A study published in PLOS Pathogens found that estradiol, a female sex hormone, enhances anti-viral responses in mice infected with HSV-2. The researchers discovered that estradiol primes dendritic cells to initiate anti-viral T cell immunity, providing protection against STIs.
A McMaster University research team is examining how environmental factors, such as agricultural practices and toxicants, affect brown adipose tissue activity in individuals with obesity or type-2 diabetes. The studies aim to develop new strategies to enhance BAT activity for treating and preventing these diseases.
Scientists at McMaster University have made a breakthrough in understanding the regulation of human blood stem cells, allowing for better control and regeneration. The discovery could lead to more people receiving treatment for life-threatening diseases, reducing healthcare costs and wait times.
Researchers at McMaster University found that a single minute of very intense exercise produces health benefits similar to longer endurance training. Brief bursts of intense exercise are remarkably effective in boosting cardiorespiratory fitness and insulin sensitivity.