Researchers at McMaster University have successfully coaxed tellurazole oxides into assembling themselves into cyclic structures, a major advance in supramolecular chemistry. The discovery creates potential for useful new materials in areas such as communication technologies, gas storage, and catalysis.
McMaster University has received $3.3M in funding to address auto industry and nuclear safety challenges through two research projects, the CaNRisk program and CREATE Program in Hybrid Electric Vehicle Powertrain Design and Development.
Researchers found that individuals who inject drugs are more likely to relapse during treatment, while those starting opioid abuse at an older age have a lower risk. The study suggests tailoring treatment to each patient's needs and targeting aggressive therapies for high-risk patients.
Researchers at McMaster University have identified a critical step in the immune system's recognition of DNA viruses, which could lead to vaccinations for herpes, the common cold, and even cancer. The discovery involves an interaction between proteins S6K1 and STING that triggers antiviral responses.
A recent study published in the New England Journal of Medicine found that taking statins and antihypertensives can reduce cardiovascular disease events by 25-30% in patients at intermediate risk. The research also suggests that combining these medications can be an effective way to prevent heart attacks and strokes globally.
Seven McMaster researchers received funding from NSERC to develop innovative technologies, including more efficient solar cells and infrared photodetection. The projects aim to create jobs and stimulate economic growth.
Scientists René Heller and Ralph Pudritz suggest focusing on Earth's transit zone, where our planet passes in front of the sun, to maximize the chances of detecting signals from extraterrestrial observers. The proposed method involves studying the dimming of starlight as a planet crosses its host star's face.
Researchers confirm shelled mammal as armadillo's ancestor, revealing recent ancestral connections that have long fascinated biologists. The study sheds light on the glyptodont's place within the Xenarthra group and its extinction during the Ice Age.
Premature babies born with low birth weight are more likely to be bullied and develop depression, anxiety, ADHD, or antisocial behavior in adulthood. Childhood bullying significantly increases their risk for mental health problems, particularly anxiety disorders.
Researchers found that high-protein diets combined with intense exercise can lead to significant muscle gain while losing body fat. The study involved 40 young men who followed a low-calorie diet with varying levels of protein, resulting in impressive muscle gains and weight loss.
Researchers found that the bacterium Yersinia pestis persisted in Europe, causing repeated devastating waves of plague epidemics. The discovery sheds light on the evolutionary history of the pathogen and its potential role in modern-day antibiotic resistance.
A study by McMaster University found that teenagers with food allergies are more likely to have depression, anxiety, or attention-deficit hyperactivity disorder (ADHD) compared to their peers without allergies. Mothers of teens with food allergies are also more likely to report these emotional and behavioral problems.
Aging is associated with chronic low-level inflammation, which can impair white blood cells' ability to fight infection. Reducing inflammation in older adults helps clear infections and improve recovery.
Researchers at McMaster University have discovered a clear and compartmentalized sequence of events leading to the development of acute myeloid leukemia (AML) from myelodysplastic syndromes (MDS). The study provides an early and accurate prediction tool for this aggressive cancer.
A physically active lifestyle can substantially decrease the genetic effect of the major obesity gene FTO on body weight in a multiethnic population. Researchers at McMaster University found that physical activity can blunt the effect of inherited obesity genes by up to 75 per cent.
Researchers from McMaster University successfully tracked individual catalyst nanoparticles during heating using advanced electron microscopy techniques. This breakthrough could lead to the development of less expensive catalysts, such as platinum-iron nanoparticles, reducing dependence on imported oil and greenhouse gas emissions.
Researchers have discovered six new African frog species and added back one previously lost, increasing the known number of clawed frog species from 22 to 29. The discovery highlights striking new characteristics and sheds light on evolution through DNA analysis.
Researchers at McMaster University found that using saline water instead of soap and water can lead to lower rates of infection and complications. The study involved 2,400 patients with open fractures and showed that low-pressure saline irrigation was an acceptable alternative to traditional cleaning methods.
Researchers at McMaster University have developed an antidote that reverses the effects of two new blood thinners, apixaban and rivaroxaban, within minutes. This breakthrough may help save lives by quickly reversing bleeding complications in emergency situations.
A study found that more than half of female methadone clinic patients started with doctor-prescribed painkillers, while men were more likely to be working and smoke cigarettes. The researchers highlighted the need for better treatment options tailored to women's demographics and health needs.
A radical shift is needed in how heart medicines are provided and preventive care is organized in healthcare systems to improve rates of use. Generic versions of medicines should be made available for free in developing countries, while non-physician health workers can improve uptake and adherence.
Researchers develop lightweight and high-power density capacitors using nanocellulose-based materials, paving the way for more efficient and environmentally friendly electronics. The new devices offer faster charging abilities and can accumulate energy during braking to release it during acceleration.
Research from the South Asian Birth Cohort study suggests that South Asians may be at risk for developing type 2 diabetes immediately after birth due to higher levels of adipose tissue and waist circumference.
A McMaster University hematologist has identified various limb loss syndromes, including symmetric peripheral gangrene and venous limb gangrene, which can be caused by septic shock, cancer, and blood clotting disorders. The treatment for these conditions involves the use of blood thinners and replacement of protective factors.
A study published in the British Medical Journal found that trans fats are associated with a 34% increase in death for any reason, while saturated fats showed no clear association with an increased risk of death or heart disease. However, researchers recommend replacing high-fat foods with vegetable oils, nuts, and whole grains.
A study published by McMaster University has shown that corticosteroid therapy significantly benefits patients with community-acquired pneumonia. The research found that corticosteroids can reduce the need for mechanical ventilation from 9% to 5% of patients and decrease the risk of life-threatening complications.
Researchers found that early life stress can alter gut microbiota, leading to anxiety and depression-like behavior. Transplanting stressed mice with altered bacteria into germ-free mice showed the bacteria's impact on host behavior, highlighting the complex interaction between gut microbiota and its host.
A study found that additional radiation to lymph nodes reduces breast cancer recurrence, but does not increase overall survival. The treatment was associated with limited toxicity and is recommended for women with axillary node-positive or high-risk node-negative breast cancer.
A new study led by McMaster University professor Dr. Deborah Cook found that a program honoring patients' last wishes creates meaning, memories, and closure at death. The Three Wishes Project, which involved 40 dying patients and their families, resulted in the implementation of 97.5% of requested wishes.
Researchers have developed a highly sensitive test to detect infectious diseases like hepatitis C and superbugs. The new method can pick up tiny traces of metabolites, proteins or DNA fragments, making it 10,000 times more sensitive than other detection systems.
Studies show that certain bacterial groups in the gut can help protect against inflammation and control symptoms of UC. Researchers found that fecal microbiota transplantation with specific beneficial bacteria may be a promising treatment option for UC.
A new study reveals that AMPK, the body's fuel gauge, is essential for slowing muscle wasting with aging. Researchers found mice lacking AMPK in their muscles developed significant muscle weakness.
Researchers at McMaster University have developed a technology to convert adult human blood cells into functional neurons, providing insights into pain perception and potential new treatments. This breakthrough could lead to the development of personalized pain medications that target specific neural pathways.
A study published in The Lancet found that firmness of hand grip is a better indicator of health than blood pressure. Researchers analyzed data from over 140,000 adults and found that reduced muscular strength measured by grip strength was consistently linked to early death, disability, and illness.
Researchers at McMaster University have developed a new way to print paper biosensors that can quickly diagnose bacterial and respiratory infections. The technology uses conventional office ink-jet printers to produce paper sensors with high molecular weight, enabling the detection of specific disease biomarkers.
Scientists have found that senataxin, a protein associated with neurodegenerative diseases, plays a key role in the body's natural antiviral response. Abnormal inflammation generated by senataxin deficiency may contribute to disease progression in conditions like ALS.
Researchers at McMaster University found that women's muscle appears more efficient in neutralizing the protein PTEN, which reduces insulin resistance and increases protection against type 2 diabetes. This discovery provides a potential therapeutic target for improving muscle responses to insulin and treating the disease.
A large study has found that routine blood clot removal during heart attack treatment does not benefit patients and may increase the risk of stroke. The TOTAL trial involved over 10,700 patients and showed no differences in cardiovascular outcomes between those who received clot removal and those who did not.
Recent studies by McMaster University researchers found that preventing weight gain is challenging for all ages, while keeping lost weight off is also tough. Small weight losses, however, can have a positive impact on health.
A new electronic model developed by McMaster University researchers aims to revolutionize shared decision-making in doctor's offices. The SHARE-IT decision aids provide simple formats for patients to review medical information and evidence, promoting meaningful conversations between patients and doctors.
A study found that extremely low birth weight babies are more likely to develop psychiatric problems like depression and ADHD as adults. However, those who received steroids during pregnancy were not protected against these issues.
A Canadian multicenter survey of over 1,200 hospital-based clinicians identified key barriers to end-of-life care discussions with seriously ill patients and their families. The study found that factors such as difficulty accepting a poor prognosis, limited understanding of life-sustaining treatments, and disagreements among family mem...
A recent study published in PEDIATRICS found that morphine administered for post-operative pain in children who have undergone tonsillectomy with or without adenoidectomy can cause significant respiratory problems and potentially fatal breathing disruptions. In contrast, ibuprofen was shown to be a safe and effective alternative.
Researchers at McMaster University have discovered a new class of antibodies that can neutralize a wide range of influenza A viruses, paving the way for a universal flu vaccine. The vaccine would only need to be given once and could protect against all strains of flu, even when the virus mutates.
Researchers from McMaster University have identified a key hormone responsible for reduced brown fat activity in obese individuals, leading to increased risk of obesity and diabetes. Blocking the production of peripheral serotonin enhances brown fat activity, providing a potential new treatment approach.
Scientists at McMaster University have discovered that human induced pluripotent stem cells retain a memory of their original tissue type, allowing for more targeted regeneration and therapy development. This breakthrough challenges the conventional thought that any pluripotent human stem cell can be used to generate mature tissue cells.
Researchers found that minimally invasive disc surgery does not support the routine use of the procedure, as it does not improve long-term outcomes. The study suggests that conventional open discectomy surgery often provides better results for carefully selected patients.
Patients with a history of heparin-induced thrombocytopenia (HIT) may be ready for urgent heart surgery sooner than previously thought, according to new research. A combination of appropriate blood screenings and therapeutic plasma exchange can help lower HIT antibody levels quickly.
A study published in CMAJ found that hospitalized patients and families prioritize discussing preferences for care, patient values, prognosis of illness, fears or concerns, and additional questions regarding care. However, these elements are infrequently discussed, leading to low concordance between preferred and prescribed goals of care.
A study conducted by McMaster University researchers found that hospitalized patients wash their hands infrequently, with rates as low as 3% when entering and leaving their rooms. The research emphasizes the importance of educating patients on hand hygiene practices to reduce the spread of infection.