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Northwestern University


Coaching scientists to play well together

A new study from Northwestern University shows that a free online training tool can significantly boost scientists' knowledge of team science and increase their self-confidence. The COALESCE tool has been validated by research to help scientists collaborate smoothly, reducing disputes over data access and authorship.

SourceNorthwestern University·JournalJournal of Clinical and Translational Science·DateJul 18, 2019

Many of the deadliest cancers receive the least amount of research funding

A Northwestern University study found that many deadliest cancers, such as colon, lung, and liver cancer, receive significantly less nonprofit research funding than breast cancer, leukemia, and other well-funded types. This underfunding could impact research, drug development, and FDA approvals for these life-altering diseases.

SourceNorthwestern University·JournalJournal of the National Comprehensive Cancer Network·DateJul 18, 2019

'Trojan horse' anticancer drug disguises itself as fat

A stealthy new drug-delivery system has been developed that disguises chemotherapeutics as fat, allowing it to penetrate and destroy tumors while minimizing side effects. The system uses a long-chain fatty acid with two binding sites to attach to drugs, which are then carried by human serum albumin throughout the body.

SourceNorthwestern University·JournalJournal of the American Chemical Society·DateJul 18, 2019

Do women regret embryo testing before IVF?

A study found that 94% of patients who underwent embryo genetic testing before IVF were glad to have the information, despite potentially disappointing results. The research suggests that even after a negative outcome, most women value the knowledge gained from embryo testing for reproductive planning.

SourceNorthwestern University·JournalHuman Reproduction·DateJun 21, 2019

The brain consumes half of a child's energy -- and that could matter for weight gain

A new paper suggests that variation in brain energy expenditure during childhood may influence patterns of energy expenditure and weight gain. The study proposes a hypothesis linking the brain's energy demand to obesity risk, highlighting the need for further research into the role of brain development on body weight.

SourceNorthwestern University·JournalProceedings of the National Academy of Sciences·DateJun 17, 2019

Parents of depressed teens in treatment may also benefit from counseling

A new Northwestern University study suggests that parents of depressed teenagers should also receive counseling to address their marital relationships and parent-child conflicts. The research found that while the teenager's depression was being treated, parental marriages and conflict remained stable, but worsened after treatment ended.

SourceNorthwestern University·JournalJournal of Abnormal Child Psychology·DateJun 6, 2019

Heart failure deaths rising in younger adults

Death rates due to heart failure are increasing among younger adults under 65, with black men under age 65 facing the largest increase in premature death. The study found that an estimated 6 million adults in the US have heart failure, which is the number one reason older adults are admitted to hospital.

SourceNorthwestern University·JournalJournal of the American College of Cardiology·DateMay 6, 2019

Vaccine design can dramatically improve cancer immunotherapies

Researchers at Northwestern University have designed spherical nucleic acids (SNAs) that stimulate powerful anti-cancer immune responses, completely eliminating tumors in 30% of animals and improving overall survival. The study's findings highlight the importance of chemical structure and three-dimensional presentation in vaccine design.

SourceNorthwestern University·JournalProceedings of the National Academy of Sciences·DateMay 6, 2019

Why you love coffee and beer

A genome-wide test suggests that bitter and sweet beverage preferences are related to the psychoactive properties of these beverages, not genetic variations in taste genes. People prefer certain drinks due to their emotional and psychological impact.

SourceNorthwestern University·JournalHuman Molecular Genetics·DateMay 2, 2019

Making glass more clear

Researchers have developed an energy renormalization algorithm to predict glass' mechanical behavior at varying temperatures. This approach enables the design of dynamic materials with optimal properties, scaling molecular simulations up by roughly a thousand times.

SourceNorthwestern University·JournalScience Advances·DateApr 30, 2019

Eyes reveal early Alzheimer's disease

Researchers detected vascular changes in the human eye using an infrared camera, providing a new potential biomarker for identifying individuals at high risk of progressing to Alzheimer's. The study aims to explore the correlation between retinal capillaries and other brain biomarkers.

SourceNorthwestern University·JournalPLOS ONE·DateApr 5, 2019

Poverty leaves a mark on our genes

A Northwestern University study found that poverty can become embedded in nearly 10% of the genome, associated with over 2,500 sites and 1,500 genes. This epigenetic mark may shape gene expression and contribute to disease development.

SourceNorthwestern University·JournalAmerican Journal of Physical Anthropology·DateApr 4, 2019

Just an hour of weekly walking staves off disability

A new Northwestern Medicine study found that an hour of weekly moderate-to-vigorous physical activity can help older adults maintain their independence and reduce the risk of mobility disability by 85%. The study also showed that this amount of exercise can lower the risk of activities of daily living disability by almost 45%.

SourceNorthwestern University·JournalAmerican Journal of Preventive Medicine·DateApr 1, 2019