A new Northwestern University study reveals that the percentage of African ancestry influences gene production, affecting disease risk and medication response. The research highlights the importance of considering individual ancestry in precision medicine and drug discovery for diverse populations.
Researchers have made significant breakthroughs in cell-free gene expression, enabling high-yielding protein synthesis and expanding genetically encoded chemistry. This has opened doors to create new types of enzymes, materials, and therapeutics. Northwestern University's Center for Synthetic Biology is at the forefront of this field.
A new method has been developed to accelerate the development of protein therapeutics by utilizing a cell-free system for glycosylation. This approach enables researchers to quickly discover and understand glycosylation pathways, leading to faster medicine creation and potentially opening up new avenues for treating diseases.
Northwestern University researchers create a thin, wireless system that adds a sense of touch to virtual reality experiences, enabling new applications in social interactions, prosthetics, telemedicine, and entertainment. The device transmits touch patterns through miniature vibrating actuators embedded into a soft, flexible material.
A Northwestern University study combines 3D climate modeling with chemistry to explore the habitability of planets around M dwarf stars. The research finds that only planets orbiting active stars lose significant water to vaporization, making them less likely to sustain life.
A new Northwestern University study found that toddlers with language delays are nearly twice as likely to have severe and frequent temper tantrums. The research surveyed over 2,000 parents and discovered a link between delayed vocabulary and increased risk of later mental health problems.
Researchers at Northwestern University have discovered a new phenomenon in the brain where mitochondria self-destruct, leading to early stages of neurodegeneration. The study found that this process occurs selectively in neurons vulnerable to future degeneration, providing a potential target for drug therapies.
Non-Hispanic black and Hispanic women reported higher pain scores compared to white women during the postpartum period. Despite this, they received fewer opioids and were less likely to receive prescriptions at discharge.
Researchers found that individuals go on to achieve eventual success if they learn from previous failures and apply that knowledge forward, whereas others continue to fail until they drop out. The model can aid in making better use of past failed experience for achieving success.
Northwestern University chemists create molecules with specific chemical products and arrangements of atoms, suitable for drug development. The catalyst can be reused for additional reactions, producing high yields.
A new study found that women surgical residents are more likely to experience mistreatment, including verbal abuse, sexual harassment, and pregnancy/childcare discrimination, leading to higher burnout rates. The study also revealed that 5.3% of women surgical residents had suicidal thoughts in the last year compared to 3.9% of men.
Researchers at Northwestern University have developed a new way to pre-program microfluidic devices, allowing for smart, autonomous behavior without external components. This breakthrough could enable the creation of portable, wearable technologies for applications in medicine, energy, and space exploration.
Researchers at Northwestern University have developed a new catalytic method to upcycle single-use plastics into high-quality liquid products, such as motor oils, lubricants, and cosmetics. This breakthrough improves current recycling methods, producing fewer greenhouse gases and toxic byproducts, while contributing to a circular economy.
A new phase 2 clinical trial shows that technology can induce immune tolerance to gluten in individuals with celiac disease, reducing inflammation and protecting the small intestine. The treatment, called CNP-101, is a biodegradable nanoparticle containing gluten that convinces the immune system it's safe.
A Northwestern University research team discovered similarities in RNA folding among riboswitches, which could impact the design of future RNA-specific therapeutics and synthetic biology tools. The findings could also inform efforts to treat diseases triggered by RNA-level misfolding.
Northwestern University researchers have developed HARP, a high-throughput 3D printer that can print large parts in hours and small parts at high resolutions. The technology bypasses heat limitations with a nonstick liquid interface, enabling fast and large-scale manufacturing without molds or warehouses.
A new strategy to treat Parkinson's disease has been developed by amplifying healthy GCase enzymes, alleviating symptoms in both human brain cells and mouse models. This approach may be relevant for multiple forms of PD with reduced activity of wild-type GCase.
Northwestern University researchers have discovered a new method to control the formation of scroll-like cochleate structures, which could inform future drug-delivery strategies. By regulating electrostatic interactions and elastic energies, they were able to capture and release macromolecules in a size-selective manner.
Researchers developed a bioelectronic implant that can sense dangerously low oxygen levels and administer naloxone to prevent opioid deaths. The device is small, wireless, and can be implanted just beneath the skin to bypass barriers in current overdose treatment.
Northwestern University researchers have successfully integrated graphene and borophene into 2D heterostructures, enabling the creation of ultrahigh density devices. The achievement demonstrates a significant step towards creating integrated circuits from these nanomaterials.
A study by Northwestern University found that sleep-deprived individuals are more likely to choose high-energy dense foods due to an imbalance in brain regions receiving food signals. The researchers suggest that paying attention to our nose's influence on food choices may help alleviate unhealthy snacking habits.
A new predictive model can forecast a terror organization's future violence after just 10 attacks, allowing security forces to identify and neutralize the most destructive groups. The model, developed by Northwestern University researchers, uses data from publicly available sources like the Global Terror Database.
A new study from Northwestern University suggests that human ecology has played a more significant role in shaping the human gut microbiome than genetic relationships. The research found that the human gut microbiome is more similar to that of Old World monkeys like baboons than apes like chimpanzees.
An interdisciplinary team from Northwestern University has developed a non-invasive imaging platform to study coral nanoscale structures and quantify pigment absorption in live corals. This tool could help researchers develop strategies to prevent coral reef death due to climate change.
A new blood test can detect liver cancer and life-threatening vascular complications in diabetic patients with high accuracy. The test analyzes DNA in just a few drops of blood and has already shown promise in detecting other major cancers.
Researchers found that early-career failure leads to greater success for those who try again, with near-miss scientists publishing more hit papers than their just-made-it counterparts. The study suggests a counter-narrative to the Matthew Effect, highlighting the value of failure in future career impact.
A new tool, HWISE Scale, measures household water insecurity in low- and middle-income countries. It provides actionable information to address the global water crisis, strongly associated with food insecurity, stress, and economic productivity.
A new treatment approach for metastatic prostate cancer has shown promising results, delaying disease progression by more than double and potentially extending lives. The treatment targets genetic alterations that enable cancer cells to repair themselves, leading to significant extensions in time before the disease grows and spreads.
Researchers found that natural selection acts on signal-sensing receptors, influencing a worm's decision to stay or enter dauer based on the availability of resources. The study provides evidence that artificial and natural selection work similarly, supporting Darwin's hypothesis.
Researchers developed a tiny nanolaser that can function inside living tissues without harming them. The nanolaser shows promise for imaging in living tissues and can operate in extremely confined spaces.
A new study from Northwestern University explains why big cities generate more crime: it's easier for criminals to find collaborators. The study found that certain types of crime, such as robbery and car theft, exponentially outpace the population.
Researchers at Northwestern University have developed a method to create highly active catalysts from precious metal nanoparticles, improving fuel cells' efficiency. The new catalysts can also be recycled from spent catalysts, reducing waste and increasing their lifespan.
Researchers developed a new model that shows rubbing two objects together produces static electricity by bending tiny deformations on the surface of materials. This phenomenon, called flexoelectricity, arises from the separation of charge in an insulator due to deformations such as bending.
An international team of astronomers has detected radio bubbles with South Africa's MeerKAT telescope, revealing a massive hourglass-shaped structure hundreds of light-years tall. The discovery is believed to be the result of an energetic burst near the supermassive black hole, providing insights into the Milky Way's central region.
A team led by Northwestern University has captured the deepest optical image of a first neutron star collision using NASA's Hubble Space Telescope. The study sheds light on the nature and origin of neutron star collisions, including the jet created during the merger and its relation to shorter gamma ray bursts.
A team of researchers, including Northwestern University professor Gary Galbreath, analyzed the physical condition of the antlers and confirmed they belonged to a Schomburgk's deer. The antlers showed signs of being fresh, despite being excised from the deer's head, suggesting the deer may still be alive today.
Scientists have pinpointed dysfunctional brain networks responsible for impaired speech and word finding in primary progressive aphasia (PPA), a type of dementia. The study found three brain regions that fail to communicate, leading to difficulties with sentence production, word comprehension, and word naming.
A large-scale analysis of partisan WhatsApp groups found that right-wing users shared substantially more multimedia content and YouTube videos than left-wing groups. This study suggests that media literacy has not kept up with rapid technological changes, making it challenging to evaluate information received.
A new Northwestern Medicine study finds total heart disease deaths increasing since 2011, with a significant portion of deaths preventable. The study's authors call for a shift in focus towards prevention to combat cardiovascular disease.
A Northwestern University study found that white parents with higher racial bias awareness are more likely to discuss race with their children, promoting increased color consciousness and decreased color blindness. This could have implications for interventions to reduce racial biases in childhood.
A new Northwestern University study discovered that spaceflight consistently changes the abundance and diversity of gut bacteria in mice. Using a novel analytical tool called STARMAPS, researchers found that spaceflight causes a specific change on the microbiome, but ruled out radiation as the cause.
A Northwestern University study found that the Violence Reduction Strategy (VRS) program reduced gunshot victimization among participants by 3.2 percentage points, with spillover effects reducing victimization among their peers by 1.5 percentage points. These findings suggest that social networks can be leveraged to enhance gun violenc...
A Northwestern University study found that people acquire attitudes toward individuals based on nonverbal signals, including implicit biases. The researchers discovered that participants attributed their negative attitudes to the target's behavior rather than the observer's actions, highlighting the importance of considering the role o...
Northwestern University scientists have received a $3.1 million grant to investigate drug therapies for ALS, targeting protein aggregation and upper motor neurons. Promising early results suggest compounds may have broader applications for neurodegeneration.
Researchers at Northwestern University discovered that mixing strong and weak graphene oxide flakes can create stronger paper, improving the material's durability. The finding sheds light on a general problem in materials engineering and has implications for other two-dimensional materials.
Researchers developed a new method to analyze nanoparticles' movements in real-time, finding that targeting nanostars rotate faster and move across larger areas than non-targeting counterparts. This technology holds promise for reducing side effects of cancer treatments by delivering drugs directly to diseased cells.
A new study by Northwestern University reveals sesame allergy is more common than previously known, affecting over 1.5 million individuals in the US. The study found that sesame is often a hidden ingredient in foods, increasing the risk of accidental ingestion.
A Northwestern University study found that police officers who had colleagues previously named in use-of-force complaints were more likely to be named in subsequent complaints. The researchers recommend police departments consider the impact of assigning officers with histories of using excessive force on other officers' behavior.
Scientists have discovered a new method to generate electricity using water flowing over thin metal layers. The oxide layer atop the nanometal layer results in an electron shuttle, allowing for efficient energy conversion.
Researchers found that slowing metabolic rates can prevent developmental problems caused by genetic mutations in fruit flies. The study suggests that reducing metabolism by 50% allows for adjustment and correction of errors, thereby preventing detrimental effects.