A new study reveals that pauses in speech can provide information about how people's brains plan and produce speech. The research found that neighboring brain regions play a crucial role in speech planning, with longer latencies corresponding to planning and shorter latencies indicating physical mechanics of speaking.
A genetic analysis of hospitalized Covid-19 patients found that a certain IL1RN variant protects men under age 75 from severe illness and death. The study showed that the protective gene variant, rs419598, is associated with lower inflammation and reduced mortality in men up to age 74.
Researchers discover that PD-1 forms dimers to function optimally, and manipulating its dimerization can enhance or inhibit T cell activity. This finding offers new insights into developing more effective cancer immunotherapies and treatments for autoimmune diseases.
A new study uses synthetic DNA to show that yeast and mammalian cells have distinct transcription patterns, with yeast constantly transcribing genes and mammalian cells repressing them. The findings could help understand the functions of non-gene-related transcription and guide engineering of yeast for new medicines or gene therapies.
A new study finds that generative AI can accelerate the design of healthcare software, particularly for complex medical problems like diabetes prevention. Researchers at NYU Langone Health used ChatGPT to develop a personalized automatic messaging system in over 40 hours, compared to 200 programmer hours with non-AI enabled efforts.
A study found an insertion of DNA shared by apes and humans but missing in monkeys that affected tail length. The insertion, called AluY, influenced alternative splicing to result in a variety of tail lengths.
A study of over 3,500 men with prostate cancer found that a plant-based diet significantly improved measures of sexual function, urinary health, and vitality scores. The research suggests that adding more fruits and vegetables to the diet while reducing meat and dairy can have a positive impact on quality of life.
A new study reveals that backtracking, a molecular event, occurs frequently throughout the genome and influences thousands of human genes. Persistent backtracking is linked to various biological processes, including cell division and tissue development.
Seizures of psilocybin, a hallucinogenic compound found in psychedelic mushrooms, have surged by 369% across the US since 2017, according to a new study. The highest number of seizures were recorded in the Midwest and West regions, with nearly quadrupled amounts of seized drugs.
A new study links daily exposure to phthalates, used in plastic food containers and cosmetics, to nearly 56,600 preterm births in the US in 2018. The resulting medical costs are estimated to reach $1.6 billion to $8.1 billion over the lifetime of the children.
Researchers have found that a gene-based therapy targeting plakophilin-2 can interrupt the progression of arrhythmogenic right ventricular cardiomyopathy, a rare inherited disorder. The treatment reduced episodes of arrhythmia and slowed the deterioration of the heart's walls in mice.
A new study published in Nature found that a distinct area on the underside of the hypothalamus influences longer-lasting avoidance behavior after being defeated. The research suggests that oxytocin plays a key role in this process, binding to receptors on brain cells and signaling danger.
A new study from NYU Grossman School of Medicine and University of Illinois Urbana-Champaign reveals a trick to understand how genes are turned on and off in bacteria, providing clues to combat antibiotic resistance. The researchers used single-cell sequencing and fluorescence hybridization techniques to track gene activity in real-time.
Research reveals that stable and supportive caregiving during childhood can protect cardiovascular health later in life, contrary to previous findings on childhood adversity. The study analyzed over 2,000 participants and found that each additional unit score of caregiver warmth was associated with 11.7% higher odds of cardiovascular h...
A new study found that households with high incomes, private health insurance, and older adults are more likely to have life support withdrawn after a severe brain bleed. This study aims to address disparities in healthcare by providing insights into social and economic factors influencing end-of-life conversations.
Researchers have identified a new strategy to combat the seasonal flu by targeting sialic acids in the upper respiratory tract of infants. Using desialylated neuraminidase enzymes, they reduced mouse-to-mouse transmission rates of influenza A by over half, suggesting potential benefits for preventing flu spread in children.
Researchers have identified brief seizures accompanied by muscle convulsions as a potential cause of sudden, unexpected deaths in young children. A study analyzed data from over 300 SUDC cases and found that five out of seven recordings showed direct evidence of seizures before the child's death.
The study highlights the need for a culturally informed approach to improve mental well-being of Black Americans, who face greater exposure to risk factors due to centuries of racism. Community-based participatory research and inclusive systems are proposed as solutions to combat systemic biases and inequities.
A new study by NYU Langone Health found that patients from lower socioeconomic areas were less likely to fill their heart-failure medications, highlighting the importance of neighborhood-level interventions to improve access to lifesaving drugs. The research team plans to explore additional barriers, such as cost and language barriers,...
Researchers at NYU Langone Health found that a protein called RhoA triggers forces that move group of 140 cells called the primordium, using a different mechanism than single cells. This study has implications for stopping the spread of cancer and understanding cellular mechanisms.
A new study found that a smaller dose of the mpox vaccine, administered in two doses spread out over weeks to months, produced a detectable immune response similar to the full FDA-approved dose. This was true for people with or without HIV, and those previously vaccinated against smallpox also had a stronger immune response.
A new study in mice shows that a hybrid treatment combining a drug and a protein fragment can prevent the growth of blood cancer cells by targeting the RAS gene mutation. The treatment, which blocks cell division and multiplication, has shown promising results in live animals with multiple myeloma tumors.
A new study suggests that analyzing genetic material from nearby healthy tissue may help predict lung cancer's return after treatment. The study analyzed RNA from tumor cells and adjacent, seemingly normal lung tissue and found that the expression of genes associated with inflammation was especially useful for making predictions.
Researchers have genetically engineered mice with human-like ACE2 protein, allowing them to develop symptoms similar to young humans infected with COVID-19. This breakthrough model has the potential to study disease impact and treatment approaches more effectively.
A brain injury expert is calling for reforms to the Uniform Determination of Death Act, citing support from 83% of medical and advocacy organizations. The expert argues that the legal definition of death should align with medical standards, including clarifying what brain functions must be lost to declare someone legally dead.
A new study suggests an artificial intelligence tool can detect distress in hospital workers' conversations with therapists during the pandemic. The tool analyzed digitalized session transcripts to identify common phrases tied to mental illness using natural language processing.
Researchers have discovered a new mechanism for starving pancreatic cancer cells, potentially leading to improved treatment outcomes. A combination of treatments involving the drug DRP-104, which blocks glutamine metabolism, and trametinib, an existing ERK signaling pathway blocker, showed promising results in mouse models.
A new study shows that XEN1101 can reduce seizure frequency by more than 50% in some patients and sometimes eliminate seizures altogether. The medication, a potassium-channel opener, boosts the flow of potassium out of nerves to stop them from firing.
A new study reveals that COVID-19 triggers a dangerous immune response in hardened fatty deposits lining the heart's largest blood vessels. This inflammation can lead to immediate and longer-lasting heart issues, including plaque rupture and blockage of blood flow.
Researchers at NYU Grossman School of Medicine found that blocking the Notch signaling pathway in aging skeletal stem cells increases bone mass and restores lost bone-healing ability. The study used single-cell RNA sequencing to reveal that Notch signaling becomes abnormally active with age, shifting cells towards fatty degeneration.
A new study published in JAMA Psychiatry found that decriminalization policies in Oregon and Washington did not lead to increases in fatal overdose deaths. The research used a rigorous quasi-experimental design and found no statistical significance in overdose death rates between the two states and a synthetic control group.
A study has identified key T cell subsets that track closely with successful vaccination and are responsible for early protection against SARS-CoV-2. The research found distinct CD8+ T cells that proliferate and attack key proteins of the pandemic virus, particularly those lacking surface protein KLRG1.
A new study in rodents reveals that infant cries prompt the release of oxytocin, a brain chemical controlling breast milk, in mothers. The study shows how sound information travels to the brain, triggering the hormone release, which continues for around five minutes.
A new NYU Langone Health program trains neurology residents to diagnose neurological ailments using simulated virtual exams. The curriculum includes 'actor-patients' and self-testing, improving residents' comfort levels and interest in teleneurology, a crucial skill for the future of healthcare.
Researchers have developed a new way to engineer bacterial enzymes, creating unique versions that are hyper-sensitive to existing antibiotics. This breakthrough could lead to the creation of more potent treatments for bacterial infections and improve our understanding of antibiotic resistance.
Researchers found that Canadian wildfire smoke exposure led to a slightly higher bump in asthma-related hospital visits compared to high-pollen days. However, other potential health effects, such as heart attacks and strokes, require further investigation.
Researchers have discovered a new scar type, reciprocal pairs, in HR-deficient cancers that create specific chromosomal changes. These findings may lead to new approaches in treating these types of cancers by blocking backup repair mechanisms.
Researchers found that dopamine and acetylcholine hormones follow constant 'ebb and flow' cycles in the brain, enabling self-driven learning and memory formation. This discovery challenges current understanding of how dopamine and acetylcholine work together in the brain.
A study found that the closure of a Pittsburgh coal-processing plant led to immediate declines in fossil fuel-related air pollutants, resulting in near-instant decreases in local heart-related emergency department visits and hospitalizations for cardiovascular diseases. The impact persisted through at least December 2018.
A new study published in JAMA Network Open found that Black Americans are more likely to trust videos about prostate cancer presented by a Black doctor. The study, led by researchers at NYU Grossman School of Medicine, involved over 2,900 participants and showed that racial diversity among healthcare providers is crucial for improving ...
A new study from NYU Langone Health found a strong link between lupus flare-ups and specific bacterial growth in the gut, particularly Ruminococcus blautia gnavus. The researchers identified 34 genes linked to the bacterium's growth in people with inflammation, highlighting its potential role in triggering autoimmune diseases.
A new study suggests that eating more calories earlier in the day may improve metabolic health by reducing blood sugar fluctuations and inflammation. The study found that participants who followed an early time-restricted feeding pattern experienced a decrease in time above normal blood glucose levels, thereby improving metabolic health.
A new study shows that saracatinib reduces inflammation in patients with atherosclerotic cardiovascular disease by more than 90% and boosts genes that help clean up plaque deposits. The experimental cancer drug may offer an effective therapy for cases where standard treatment fails to help.
Researchers at NYU Grossman School of Medicine have developed an AI tool called NYUTron that can accurately estimate patients' risk of death, length of hospital stay, and other factors important to care. The tool achieved impressive results in predicting readmission rates, improving upon standard methods by up to 7%.
A new study in mice reveals that a middle-brain region controls aggression towards young animals, while another region promotes maternal behavior. The findings suggest that the brain mechanism behind infanticide by women may be similar to that in males.
Researchers mapped inflammation features in skin cells, revealing their role in spreading to joints and triggering conditions like diabetes and heart disease. The study's findings may help explain how small skin inflammation can affect the entire body.
A new study published in The Neuroradiology Journal introduces an artificial intelligence computer program that can accurately identify changes in brain structure resulting from repeated head injury. This AI tool uses machine learning to process magnetic resonance imaging (MRI) scans and distinguish between the brains of male athletes ...
Researchers have developed an experimental decoy that provides long-term protection from SARS-CoV-2 infection in mice by binding to the virus's spike protein. The treatment was found to be highly effective, with 100% protection against lethal doses of the virus and a significant reduction in viral load.
Researchers identified 12 symptoms that most set apart those with and without long COVID, including post-exertional malaise, fatigue, and brain fog. The study's findings will help identify effective treatment strategies for people with long COVID.
A significant increase in illicit ketamine seizures in the US has raised concerns about the risks of non-medical and recreational use, as well as the presence of fentanyl. The study found a 349% rise in seizures from 2017 to 2022, with the highest numbers reported in Tennessee, Florida, and California.