A global team of experts has published guidelines for researching deaths and recalled experiences, suggesting that consciousness persists after death. The study highlights the need for further research into the nature of consciousness and its relationship to death.
Researchers found that pancreatic cancer cells trigger the breakdown of collagen proteins, which increases arginine levels and signals stellate cells to build fibrotic meshes around tumors. This process, known as desmoplasia, creates a dense environment that promotes aggressive growth and blocks access to therapies.
Researchers have designed a therapeutic that sabotages the bacterial 'drug pump', restoring antibiotic effectiveness against drug-resistant strains. The breakthrough uses antibodies to overcome structural challenges, revealing a potential new treatment against MRSA and other resistant pathogens.
A new study found that dogs and cats are exposed to potentially toxic aromatic amines in their homes, which have been linked to cancer. The chemicals were detected in over 38% of urine samples from pets, with cats showing higher concentrations than dogs.
Scientists have redefined how bacterial cells repair damaged DNA, finding that RNA polymerase plays a central role in the process. The discovery challenges existing theories and has implications for medicine, as many antibiotics and chemotherapies work by damaging DNA.
A new study found that an orally absorbed tablet containing cannabidiol (CBD) effectively reduced post-operative pain after shoulder surgery without side effects. The study showed significant pain relief and higher patient satisfaction compared to placebo, highlighting the potential of CBD as a safe and effective pain management tool.
Melanoma skin cancer cells use Alzheimer's protein amyloid beta to survive in the brain, evading immune detection. A new study reveals a potential treatment target to counter this mechanism.
A new study found that e-cigarette vapers and hookah smokers are more likely to exhale particles through their nose compared to cigarette smokers. This unique breathing pattern may expose the nose and sinuses to higher levels of emissions, increasing the risk of upper respiratory diseases.
Researchers discovered that cells in moving group push the front of their group, contrary to previous findings that they pull with their front edges. The discovery sheds light on how tissues apply force in groups to generate motion in living organisms, which could have implications for cancer spread.
A new study finds that opioid and stimulant overdose deaths have risen significantly among Black Americans, with a 575% increase in mortality rates compared to white people. The study also reveals a major shift in the geographic trends of the opioid crisis, with a significant increase in overdose deaths in eastern states.
A study found a three-fold increase in dementia risk among lonely Americans younger than 80 who didn't carry the APOE ε4 allele. Loneliness was associated with poorer executive function and changes in brain structure indicating vulnerability to Alzheimer's disease.
Researchers identified the dorsal precentral gyrus as a critical region in controlling speech, enabling individuals to adapt to feedback errors. This finding may lead to targeted treatments for conditions like stuttering and Parkinson's disease.
A new study reveals that SARS-CoV-2 infection indirectly dials down the action of olfactory receptors in the nose, leading to persistent hyposmia and changes in how people perceive smells. The discovery may also explain lingering neurological effects of COVID-19 like brain fog, headaches, and depression.
A new polygenic risk score is made from genetic variants and lifestyle factors to identify younger adults at risk of colorectal cancer. The study found those with the highest risk scores were four times more likely to develop colorectal cancers than those with lower scores.
A new international study shows that convalescent plasma, containing antibodies from recovered individuals, reduces mortality by 15% in patients hospitalized with COVID-19, particularly those with pre-existing conditions. The treatment is most effective for patients with type A or AB blood and those with co-existing diseases.
A new study found that COVID-19 patients exhibit higher levels of blood proteins indicating neurological damage compared to Alzheimer's disease patients, especially those with neurological symptoms. The study suggests a potential link between COVID-19 and an increased risk of future brain injury.
Researchers at NYU Grossman School of Medicine identified a brain circuit active during speech planning for split-second verbal exchanges. The study used electrocorticography (ECoG) to pinpoint brain areas involved in this process, including regions not previously linked to language functions.
A new study published in Nature found that valine is essential for the growth of T cell acute lymphoblastic leukemia, a type of childhood blood cancer. Blocking valine-linked genes led to decreased valine levels and stalled tumor cells from growing.
A new study found that changes in specific genes contribute to the roughly 400 sudden unexplained deaths in children aged one year and older. Nearly 9% of the analyzed DNA codes had genetic changes in genes regulating calcium function, which can cause arrhythmias and seizures, increasing the risk of sudden death.
Researchers at NYU Langone Health have successfully performed their second xenotransplantation procedure using a genetically engineered pig kidney. The procedure, part of an ongoing study, demonstrates continued promise for these genetically engineered organs as a renewable source of life-saving gifts.
A new study found that e-cigarette users are more than twice as likely to experience erectile dysfunction as non-users. The research, published in the American Journal of Preventive Medicine, suggests that e-cigarette use may be independently linked to erectile dysfunction.
A new experimental compound, RAGE229, reduces type 1 and type 2 diabetes complications by countering cell death, inflammation, and organ damage. The compound blocks the ability of a protein called RAGE to pass on inflammatory signals that injure the heart and kidneys in diabetes.
A nationwide study found that living in areas with high fast-food outlets increases the risk of developing type 2 diabetes. In contrast, a greater presence of supermarkets is associated with lower T2D incidence, particularly in suburban and rural communities.
A new study in rodents suggests that repeated stress during infancy can lead to lasting behavioral issues due to increased dopamine levels in the brain. The research team found that stressful conditions caused pups to spend less time near their mothers and peers.
A team led by NYU Langone's Robert Montgomery successfully transplanted a genetically engineered pig kidney into a human body, marking a major step forward in xenotransplantation. The procedure, performed on September 25, 2021, used a GalSafeTM pig with the alpha-gal biomolecule removed to avoid rejection.
A new study found that daily phthalate exposure may lead to 100,000 premature deaths among older Americans each year, resulting in a $40 billion to $47 billion annual economic burden. The study suggests a link between phthalate exposure and increased risk of heart disease and early death.
A new study found that toxic fatty acids produced by astrocytes can trigger cell death in damaged neurons, which may contribute to neurodegenerative diseases such as glaucoma and Alzheimer's. Blocking the production of these fatty acids in mice preserved 75% of neurons, suggesting a promising target for treatment.
A new study shows an artificial intelligence tool improved radiologists' ability to correctly identify breast cancer in ultrasound exams, with a 37% increase in accuracy. The tool also reduced the number of tissue samples needed to confirm suspect tumors by 27%.
A new study found that COVID-19 vaccinated pregnant women pass high levels of antibodies to their babies, providing protection against infection. The Pfizer-BioNTech and Moderna mRNA vaccines trigger the production of protective antibodies in mothers, which are then transferred to newborns.
A new study found that nearly half of New York City mothers who were trying to become pregnant again before the COVID-19 pandemic began stopped in the first few months of the outbreak. Additionally, one-third of women who had been thinking about becoming pregnant but hadn't yet started trying said they were no longer considering it.
A new study found that people hospitalized with COVID-19 have elevated levels of autoimmune antibodies in their blood, which are strongly linked to disease severity. Patients with high levels of these autoantibodies were five to seven times more likely to develop severe disease than those with stable antibody levels.
A new study has identified abnormal crosstalk between platelets and cells lining blood vessels as a cause of deadly organ damage in severe COVID-19 patients. The study found that protein signals from platelets can create inflammation, abnormal clotting, and damage to vessels when exposed to the pandemic virus.
A new study from NYU Langone Health found that losing weight and managing excess body fat can significantly reduce the risk of lung disease in firefighters exposed to toxic substances on 9/11. The study analyzed 20 years of data from over 5,700 first responders and identified five key factors that predict lung disease.
A new study suggests that COVID-19 deaths are driven by a buildup of coronavirus in the lungs. Researchers found that people who died from COVID-19 had 10 times more virus in their lower airways than those who survived.
A new study shows that having someone available to listen can improve cognitive resilience and reduce the risk of cognitive decline. The study found that individuals with higher listener availability had better cognitive function despite similar physical aging or disease-related changes.
A new study published in Nature found that brain signals known to help memories form may also regulate metabolism and lower blood sugar levels. Researchers discovered that clusters of hippocampal neurons firing in cycles, called sharp wave ripples, were followed by decreases in blood sugar levels, possibly through the release of hormones.
Researchers found that observing an experienced mouse mother train another female mouse to care for her pups led to the production of oxytocin in the brains of virgin females. This neural response enabled them to mimic maternal behavior without direct interaction.
A new study found that COVID-19 infection rates among infants hospitalized for potential serious bacterial infections were higher during periods of high community transmission, but lower when transmission was low. The study also found a relatively low incidence of other respiratory viruses in this age group.
A new study found that Black men are 11% less likely to receive advanced prostate cancer therapies compared to non-Black men. Despite equal access to healthcare services, the disparity persists, with Black men also being more likely to die from the disease than non-Black patients.
Researchers found that lisdexamfetamine reduced symptoms of sluggish cognitive tempo by 30% and improved ADHD symptoms by over 40%. The study suggests that the treatment may also address executive brain function deficits, prioritization skills, and procrastination.
A new study reveals that the connective tissue protein lumican promotes immune responses against bacterial infections while restraining overactive immune responses in sepsis. Lumican interacts with toll-like receptors on immune cells, stabilizing their interactions to increase activity and production of TNF-alpha.
Researchers at NYU Langone Health have developed an antibody therapy that rescues mice from a lethal muscle-weakening disease by targeting another protein in the same signaling pathway. The treatment reverses disease relapse in adult mice, offering new hope for humans with congenital myasthenia.
A new study by NYU Langone Health researchers discovered a molecular mechanism hijacked by SARS-CoV-2 that makes it vulnerable to drug candidates. The study showed that coronavirus reproduction requires chemical changes made by the human protein METTL3, which can be inhibited by the compound STM2457.
A computerized brain implant effectively relieves short-term and chronic pain in rodents, detecting brain activity linked to pain and triggering therapeutic stimulation of the prefrontal cortex. The device reduces pain intensity and is less likely to cause addiction, offering a promising new strategy for pain therapy.
A new therapy has been shown to reduce amyloid beta plaque deposits and toxic tau levels in elderly monkeys' brains, slowing neurodegeneration. The treatment also improved cognitive function in the monkeys, suggesting its potential as a therapeutic approach for Alzheimer's disease.
A new study published in Proceedings of the National Academy of Sciences suggests that surgery should precede chemotherapy for certain patients with ovarian cancer. The research used a mathematical model to examine treatment outcomes and found that complete debulking surgery followed by chemotherapy provides better results. For patient...
Researchers discovered that blocking bacterial H2S biogenesis strengthens antibiotics by inhibiting persister formation and biofilm growth, offering a novel alternative to traditional antibiotic discovery. The study suggests using small molecule potentiators to enhance the effect of major classes of clinically important antibiotics.
A new drug, sotorasib, has shown significant benefit in treating non-small-cell lung cancer patients with a specific KRAS mutation. The study found that 37.1% of patients experienced tumor shrinkage and 82% saw slowing of tumor growth.
A new study published in Annals of the Rheumatic Diseases found that patients taking methotrexate for immune system disorders have a weaker antibody response to COVID-19 vaccines. This means they may not be as protected against the virus, but further research is needed to understand the issue.
A new study analyzed over 800 coronavirus genetic samples to trace the path of the virus as it traveled across New York City during its deadly first wave. The research identified Queens and Brooklyn as major hubs of COVID-19 spread, with Queens playing a more significant role in viral transmission.