A study by NYU Langone Health shows a massive expansion of telemedicine during the COVID-19 pandemic, with virtual urgent care visits growing by 683% and non-urgent virtual care visits increasing by 4,345%. The rapid growth was made possible by US insurers expanding coverage and state licensing relaxations.
Researchers found that pancreatic cancer cells use autophagy to degrade MHC-I proteins, making them resistant to immunotherapies. Blocking autophagy or using drugs like chloroquine enhances MHC-I expression on the surface of cancer cells, increasing their susceptibility to immunotherapy.
Researchers found that structural changes in protein bundles called chromosomes affect access to genes in T cell acute lymphoblastic leukemia. The new work shows that altering the 3D architecture of chromosomes can trigger cancer growth and spread, making targeted therapy a promising approach.
Death rates from metastatic melanoma dropped by nearly 18 percent between 2013 and 2016, thanks to new therapies that harness the immune system or target specific gene mutations. These advances in treatment have led to the largest yearly declines in deaths due to melanoma ever recorded.
Researchers at NYU Langone Health discovered a cell defense mechanism that uses tiny, protein-coated packages called exosomes to bind to and neutralize bacterial toxins. This 'soaking up' of toxins helps keep cells safe from infection.
A US population-based study found that medication treatment for opioid use disorder significantly reduces fatal overdose risk. Patients receiving treatment with opioid agonists had an 80% lower risk of dying from an opioid overdose compared to those without medication.
A comprehensive molecular study has defined key genes and proteins contributing to endometrial cancer. The research suggests tailored treatments for each patient and potential biological targets for future drug design.
Recent clinical trials of Prolonged Exposure Therapy and Cognitive Processing Therapy show limited effectiveness in treating active duty military personnel and veterans with PTSD. The studies suggest that emotionally demanding therapies may not be beneficial for all patients, and more personalized treatment approaches are needed to acc...
Sperm cells activate 90% of their genes, a pattern seen in other species, to repair DNA before passing it to the next generation. This process may influence the evolution of specific genes, with unexpressed genes containing fewer DNA code errors.
Researchers at NYU Langone Health have discovered a new role for circular RNA in regulating the spread of melanoma cancers. The study found that CDR1as blocks the aggressive growth of cancer cells, while its loss promotes it. Higher levels of CDR1as were linked to increased survival rates among patients with melanoma.
A new study found that Medicaid expansion was associated with a six percent lower rate of total opioid overdose deaths, as well as lower rates of death involving heroin and synthetic opioids. However, unexpectedly, an 11 percent increase in methadone overdose mortality was observed with Medicaid expansion.
Researchers found that pancreatic tumor cells secrete interleukin-1β (IL-1β) to reduce anti-cancer immune responses, promoting PDA tumor growth. Blocking IL-1β with an antibody treatment doubled T cell infiltration and increased PD-1 blockade efficacy by 40%.
A novel method combining optical imaging with artificial intelligence produces accurate, real-time diagnosis of brain tumors. The system, stimulated Raman histology (SRH), reveals tumor infiltration and enables surgeons to see predicted diagnoses in under two minutes.
Pancreatic cancer cells use a process called macropinocytosis to engulf nutrients, which are then broken down into building blocks for cell growth. The study identified key molecular steps involved in boosting this process, including the activation of protein kinase A and v-ATPase.
Researchers developed a computer betting game to predict opioid reuse in addiction patients. The game measures comfort with risk-taking and finds sharp increases in scores are associated with high likelihood of reuse within the next week.
A new study found that problematic marijuana use increased by 25% among adolescents aged 12-17, while past-month frequent use rose by 23% among adults aged 26 or older after recreational legalization. The study suggests investing in substance use prevention and treatment to prevent unintended harms.
Researchers found that newly cancerous pigment stem cells migrate up and out of hair follicles to establish melanomas in nearby surface skin before spreading deeper. This discovery sheds new light on the biology of melanoma and suggests potential new ideas for treatment.
New study confirms that mechanisms preserving cell identity are based on how DNA is packaged, with histone modifications playing a key role. Chemical changes to histones determine whether chromatin regions are open or compacted, influencing gene expression and cell behavior.
A new study by NYU researchers found that children living within a half-block of fast-food outlets were 20% obese and 38% overweight. The farther away from unhealthy food sources, the lower obesity rates, with significant reductions at just one or two blocks distance.
A new study in rats reveals the extent of brain damage caused by short-term maternal abuse, which can lead to fear and memory problems. Researchers also found that the combination of stress and abuse can restrict growth of certain parts of the brain, leading to behavioral problems.
A new AI tool, trained on a large dataset of mammography images, accurately identified breast cancer with 90% accuracy when combined with radiologist analysis. The study suggests that AI can augment human radiologists' diagnoses, reducing false-positive and false-negative results.
Zebrafish larvae's ability to coordinate movement and maintain balance improves as they age, mirroring human brain function. The study suggests that the developing fish rely on their vestibular organs to oversee improvements in coordination needed to remain horizontal.
A new study has found that e-cigarette smoke caused lung cancer and bladder issues in mice exposed to nicotine. The study, published in the Proceedings of National Academy of Sciences, found that 22.5% of mice developed lung adenocarcinomas after exposure to e-cig smoke with nicotine for 54 weeks.
Certain fungi can expand their population over a thousand-fold, encouraging pancreatic cancer growth, according to a new study. The study found that treating mice with an antifungal drug reduced PDA tumor weight by 20-40 percent.
A new study finds that increasing levels of 'good' cholesterol reversed disease in the blood vessels of mice with diabetes, reversing atherosclerosis. The study also shows that raising functional HDL levels stopped inflammation and improved cardiovascular disease processes.
The study implemented randomized quality improvement projects across NYU Langone Health, finding that changing prompts for tobacco cessation counseling increased medication prescription rates. Post-discharge phone calls were largely ineffective in improving patient satisfaction or hospital readmissions.
A recent study found that men at high risk for breast cancer can benefit from mammography screening. The study involved 1,869 men who had a mammogram between 2005 and 2017, with 41 men diagnosed with breast cancer.
A new study developed a blood-based biomarker panel that can diagnose posttraumatic stress disorder (PTSD) in male combat veterans with 77% accuracy. The panel uses genomic, metabolic, and protein biomarkers to identify genetic and cellular changes associated with PTSD.
A new study suggests that metabolites produced by the body's breakdown of toxins may protect against obstructive airway disease in 9/11 first responders. Researchers identified specific compounds, including protein-building amino acids and omega-3 fatty acids, which are found in diets rich in fish and olive oil.
A review of autopsy reports reveals that early in the HIV epidemic, the average age of death was 36, increasing to 54 by 2010 due to development of antiviral therapies. However, people are still dying predominantly from underlying disease rather than just old age, with infections like pneumonia and hepatitis C contributing to deaths.
The study found that ERK was easily switched on in ancient one-celled creatures but carefully restrained as animals evolved. Researchers identified two key changes that likely brought ERK under more control across evolution.
A recent study found that over 34% of recent LSD initiates first used the drug in the summer, while 30% of marijuana, ecstasy, and cocaine use began during this time. The researchers suggest that having extra recreational time during the summer and the growing popularity of outdoor activities may contribute to these findings.
Researchers identified a molecular mechanism that may be contributing to the global obesity epidemic. The study found that a protein called RAGE on the surface of fat cells can block fat burning when stressed, leading to weight gain. Removing RAGE from fat cells reduced weight gain in mice fed a high-fat diet.
A new study reveals that high antioxidant levels may accelerate lung cancer spread, contradicting the long-held notion that antioxidants like vitamin E prevent cancer. The research highlights a complex interplay between protein BACH1, NRF2, and heme-driven oxidative stress in facilitating cancer cell migration.
A new study has found that artificial manipulation of brain signals can improve working memory in rats, with extended ripples capturing more information when learning a new place. The findings offer insights into the mammalian brain's mechanisms and may guide future treatments for memory disorders.
A new study published in Nature Digital Medicine found that smartphone-based relaxation technique RELAXaHEAD can reduce migraine headache days by four per month. The app's success rate increased from 51% to 29% after three months, suggesting its potential as a treatment option.
A new case study from NYU School of Medicine provides a roadmap for academic medical centers to bridge the gap between clinical practice and public health. The report outlines four core approaches to improving health and reducing health inequities, including engaging community partners, transforming healthcare operations, and shaping p...
A new study found that even short stays in polluted cities can cause significant breathing problems and coughing in healthy adults, which can take at least a week to recover from. The research team analyzed lung and heart health in travelers visiting highly polluted cities like India and China.
Researchers have discovered a way to predict which patients with systemic lupus erythematosus (SLE) are most likely to respond to therapy by analyzing tissue samples from their kidneys and skin. This breakthrough could lead to personalized treatment plans for SLE patients.
Researchers developed a blood test that measures tumor DNA, allowing for early detection of treatment response in patients with stage III or IV melanoma. The study found that the test detected BRAF mutations in 93% of patients before treatment and showed improved survival rates for those whose tumors shrunk after targeted therapy.
Researchers studied how egg cells in fruit flies choose the healthiest mitochondria to pass on. They found that mitochondrial selection is triggered by a drop in Mitofusin levels, allowing for the elimination of faulty mitochondria.
Researchers found that removing the ATDC gene from pancreatic cells prevented the development of pancreatic cancer in mice. The study identified ATDC as a key player in the reprogramming of adult cells into primitive, high-growth cell types, which can lead to cancer.
Researchers identified nine types of cells and subtypes in the marrow microenvironment, including vascular endothelial cells and stem cells. The study revealed a critical role of subsets of cells involved in cancer chemotherapy and immune cell production.
A new study uses AI to analyze voice patterns and diagnose post-traumatic stress disorder (PTSD) in veterans. The tool was able to distinguish between the voices of those with or without PTSD with high accuracy, suggesting a potential breakthrough in telemedicine approaches.
A new study identifies 20 common sleep myths that can lead to poor habits and serious health risks. The researchers suggest creating a consistent sleep schedule and spending at least seven hours asleep to promote overall better health.
Researchers found that Hirschsprung disease shares common genetic mechanisms with complex disorders like schizophrenia and autism. The study identified key genes, cellular mechanisms, and molecular targets for personalized treatment.
A new study by NYU School of Medicine found that shorter stays in skilled nursing facilities (SNFs) are associated with a higher risk of hospital readmission among elderly heart failure patients. Patients who stayed at SNFs for two days or less had a risk four times higher than those who stayed longer.
A new study found that cancer patients use more potent forms of medical marijuana with higher amounts of tetrahydrocannabinol (THC), relieving symptoms and side effects of cancer treatment. Non-cancer patients, on the other hand, prefer CBD-rich formulations for their therapeutic benefits.
Chronic inflammation, not aging, is the main reason why bones heal more slowly with age. Researchers found that exposure to older mice's blood serum reduces stem cell multiplication and increases inflammation. Treatment with anti-inflammatory drugs restored skeletal stem cell function and bone healing ability in aged mice.
Researchers studying Alston's singing mouse found a brain circuit that enables fast back-and-forth conversation, like human talking. The motor cortex is necessary for vocal interaction, and separate circuits enable rapid starts and stops.