Researchers at NYU Langone Health have found a strong link between systemic lupus erythematosus (SLE) and an abnormal mix of bacteria in the gut. The study showed that patients with SLE had significantly higher levels of Ruminococcus gnavus bacteria in their guts, which triggered immune reactions and disease flares.
A new study found that increased marketing of opioid products to physicians is associated with higher opioid prescribing rates and elevated overdose deaths in the US. The research suggests that even low-value payments or subtle marketing tactics can influence physician prescribing patterns, leading to more overdose deaths.
A new class of centyrins shows promise in blocking the effects of severe S. aureus bacterial infections in mice and human cell experiments. Nearly all centyrins that bind to leukotoxins prevent toxins from attaching to and destroying cells, potentially addressing antibiotic resistance.
A recent study surveyed 450 oncologists in the US, revealing that most are unaware of how to treat patients with LGBTQ+ differences but are interested in learning more. The researchers recommend establishing protocols for treating LGBTQ cancer patients and providing education and training for physicians.
A new model predicts PTSD risk with high accuracy, identifying individuals at significant risk for early intervention. The model, developed from a large international study, analyzes trauma scores and estimates each individual's risk of chronic PTSD.
A new study identified a unique strain of CA-MRSA driving antimicrobial resistance and spread, particularly in vulnerable populations. Genomic surveillance played a crucial role in tracking the outbreak and informing infection control strategies.
Researchers have developed new techniques to identify which of our genes are influenced by ancient viral DNA snippets, revealing complex interactions between viruses and human genetic material. The study found that a single transposon can control multiple genes, increasing the complexity of its impact on health and disease.
A new study found that Streptococcus pneumoniae bacteria that occupy human host tissue first are more likely to thrive than competing strains. The researchers discovered that these 'owners' release toxins to kill intruders, while also releasing protective factors to defend themselves.
A new combination therapy involving ipilimumab, nivolumab, and brentuximab vedotin safely reduces tumor size or spread in 95% of patients with recurrent Hodgkin lymphoma, achieving complete remission in 16 patients.
Researchers found that checkpoint blockade therapy can sensitize patients to better respond to future use of drugs, even when initial attempts failed. This breakthrough has significant implications for treating relapsing non-Hodgkin lymphoma and Hodgkin lymphoma patients.
A team of researchers at NYU Langone Health has successfully regrown hair strands on damaged skin by stimulating fibroblasts to secrete collagen through the sonic hedgehog signaling pathway. The study offers new hope for treating hair loss and may lead to the development of more effective drugs.
A recent study discovered a genetic regulatory mechanism that controls the production of interferon beta, which causes inflammation and activates immune cells. Interfering with specific enzymes involved in RNA methylation may represent a new approach to treating autoimmune diseases.
A study of 150 popular YouTube videos on prostate cancer found that 77% had factual errors or biased content, while only 53% adequately described potential harms and side effects. Researchers urge viewers to consult credible sources for accurate information on prostate cancer.
A new study reveals that adults identifying as lesbian, gay, or bisexual are more likely to misuse opioids than heterosexual counterparts. Women who identify as bisexual are particularly at increased risk, with twice the likelihood of misuse compared to other groups.
Researchers have found a new therapeutic target for pancreatic cancer, RIP1 Kinase, which can be used in combination with other immune-boosting therapies to increase survival rates. The study shows that the drug GSK547 helps to mount a more aggressive attack against tumor cells, doubling survival to 50 days in mice.
A phase II clinical trial found that sparsentan significantly reduces proteinuria by 45% in patients with focal segmental glomerulosclerosis (FSGS), a rare kidney disorder. The study also suggests potential implications for other kidney diseases characterized by proteinuria.
A new type of molecule blocks the action of genes that drive therapy-resistant prostate cancer growth, reducing cell proliferation by 95%. The cyclic peptoids also blocked a key growth signal in live animal tests.
A new study led by NYU School of Medicine found that a faith-based intervention delivered in churches significantly reduced blood pressure among African Americans. The intervention, which combined lifestyle changes with motivational interviewing, showed a 5.8 mm Hg reduction in systolic blood pressure after six months.
A new study finds that DNA islands can be engineered to disable Staphylococcus aureus bacteria, which are often resistant to antibiotics. The 'drone-like' vehicles deliver genetic payloads to bacterial populations, killing the bacteria and rescuing treated animals.
A new AI program can analyze lung tumor images to specify cancer types and identify genetic changes, offering a potential solution for faster diagnosis and treatment. The tool achieved high accuracy rates in distinguishing between adenocarcinoma and squamous cell carcinoma, as well as identifying altered genes linked to lung cancer.
A new study found that abnormal levels of over two dozen metabolites can predict which Sept. 11 firefighters developed lung disease and which did not. The research provides a promising approach to early detection and possible treatment of lung damage in disaster victims exposed to fine particles.
Researchers at NYU Langone Health successfully guided the regrowth of missing bone in lab animals using chemically coated ceramic implants. The implants, made from beta tricalcium phosphate and dipyridamole, were naturally absorbed by the test animals' bodies as new bone gradually replaced the devices.
Researchers fused yeast chromosomes to study reproductive isolation and its effects on breeding. The team found that viable sex cells could not be produced when the difference between chromosome numbers became too great, leading to reproductive isolation.
Researchers found that brain activity patterns shift towards stored representations of clear images, suggesting that past experiences play a significant role in perception. The study used fMRI to analyze how the brain processes blurred images and found that higher-order circuits were more affected by clear image-induced shifts.
A single course of antibiotics early in childhood may increase the risk for Type 1 diabetes, according to a study published in eLife. The research found that four bacterial species groups were significantly more abundant in the guts of mice treated with the antibiotic, and likely involved in driving progression of the disease.
A study reveals that blocking heat shock transcription factor 1 (HSF1) signaling in T cell acute lymphoblastic leukemia (T-ALL) could represent a new approach in treating the aggressive disease. The discovery identifies a subset of T-ALL patients most likely to benefit from a new therapy.
The risk of having a heart attack during pregnancy has increased by 25% among American women between 2002 and 2014, according to a new study. The study found that the death rate from heart attacks remains high despite advances in treating these conditions.
The NYC Health and Nutrition Examination Survey (HANES) found that New Yorkers are getting heavier, with obesity rates increasing among certain groups. The survey also showed high rates of depression and sleep problems, as well as persistent racial and ethnic disparities in health outcomes.
Research led by NYU School of Medicine found that physicians in small independent primary care practices (SIPs) report dramatically lower levels of burnout compared to the national average. The study suggests that independence and autonomy may provide some protection against symptoms of burnout, highlighting the importance of creating ...
A study led by NYU School of Medicine researchers found that mice genetically engineered to lack the gamma-CaMKII shuttle protein took twice as long to form a memory needed to complete a simple task. The team restored learning ability by re-inserting the human version of the shuttle protein into mice.
Researchers at NYU School of Medicine discovered that mTORC1 regulates cell crowding, which can cause proteins to solidify and interfere with cellular functions. The study suggests that malfunctioning mTORC1 may contribute to the development of aging diseases.
A new study found that only half of migraine patients referred for behavioral treatment made an appointment, citing lack of time, cost concerns, and skepticism as barriers. Despite being first-line, safe, and effective treatments, many patients are not accessing these therapies due to perceived barriers.
A new study found that cannabidiol significantly reduces seizures in patients with Lennox-Gastaut syndrome, a rare and severe form of epilepsy. The trial showed a 41.9% reduction in drop seizures for the 20 mg/kg/d CBD regimen, highlighting the potential effectiveness of Epidiolex as an treatment option.
A study by NYU Langone Health and the VA found that increasing numbers of veterans with non-aggressive prostate cancer are opting for watchful waiting or active surveillance. This shift towards more conservative treatment reflects a reversal in decades-long overtreatment, bringing care more in line with best practice guidelines.
An international study found that proposed changes to the International Classification of Diseases (ICD) could lead to a 57% reduction in moderate PTSD diagnoses. The study examined almost 4,000 individuals from six countries and showed that severe PTSD cases increased by up to 36%, while moderate cases decreased by more than half.
A new MRI component in the shape of a glove delivers clear images of bones, tendons, and ligaments moving together for the first time. The technology has potential for diagnosing repetitive strain injuries and creating a more versatile atlas of hand anatomy.
A new study finds that nurse-led task shifting combined with health insurance coverage is an effective strategy to control hypertension in Ghana. The intervention led to a greater reduction in systolic blood pressure compared to health insurance coverage alone.
Dr. Steven Galetta has been awarded the 2018 A.B. Baker Award for Lifetime Achievement in Neurological Education by the American Academy of Neurology. He is recognized for his contributions to neurological education and leadership, as well as his research on MS, concussion, and optic nerve disorders.
A recent study published in the journal Microbiome has found that drinking alcohol can disrupt the balance of oral bacteria, leading to an overabundance of harmful germs. Researchers discovered that moderate drinkers had fewer beneficial bacteria than non-drinkers, while heavy drinkers had more potentially harmful bacteria species.
Combination therapy of pembrolizumab and chemotherapy significantly improves overall survival and reduces progression risk in patients with non-squamous non-small cell lung cancer. The study found a 51% reduced risk of death compared to chemotherapy alone.
Researchers found that a specific set of brain cell signals, involving dopamine and estrogen receptor alpha, trigger a mother's instinct to retrieve her offspring. The study's findings may explain human maternal behaviors like breastfeeding and could lead to new ways to support mothers with infant care challenges.
Researchers discovered a simple bedside test that can diagnose neurodegenerative brain diseases, including Parkinson's and Lewy Body dementia. The test measures changes in blood pressure and heart rate after standing up, providing clues for healthcare providers to identify potential patients with synucleinopathies.
A team of researchers has identified a previously unknown feature of human anatomy, revealing layers of the body as interconnected, fluid-filled compartments. This discovery has significant implications for understanding organ function, disease progression, and the development of new diagnostic tools.
A new study finds that top sports leagues heavily promote unhealthy food and beverage sponsors, contributing to the escalating obesity epidemic among children and adolescents. The researchers analyzed Nielsen statistics and found that over three-quarters of promoted foods failed to meet minimal nutrition standards.
Research found that gut bacteria dominate in patients with pancreatic cancer, preventing immune system attacks on tumor cells. Antibiotics slowed cancer growth and reprogrammed immune cells to recognize cancer cells again.
A new report finds that lap-band surgery significantly reduces arthritic knee pain in extremely obese individuals, with younger patients experiencing more substantial relief. Weight loss is most beneficial for those who lose the most weight, particularly those in their 40s.
A new study by NYU Langone Health reveals that patients from lower-income areas have a significantly reduced chance of surviving anal cancer. The research, led by Dr. Daniel Becker, found a strong association between median household income and overall survival rates.
Research finds that patients with undiagnosed neurocognitive deficits have poorer short-term outcomes after hip and knee replacements. Neurocognitive impairment was prevalent in older patients and those with depression, leading to increased hospital resources and slower physical therapy progress.
A novel risk assessment tool has been developed to identify patients at higher risk of post-surgical hip replacement dislocations. The tool, used in conjunction with a treatment algorithm, resulted in a six-fold decrease in dislocation rates among high-risk patients.
Researchers found no significant difference between original and modified PersonaCARE software versions in predicting inpatient mortality. The study suggests using the tool to guide older patients toward specialized care pathways, reducing complications and costs.