A new NYU report reveals that the phase-out of Teflon-like coatings, which contain PFOA, has led to a significant decrease in low-birth weight babies and related brain damage. The study estimates that this shift has saved over $13 billion in healthcare costs and improved educational prospects for thousands of children.
Research suggests that antibiotic use in mothers may alter the microbiome of their offspring, increasing the risk for inflammatory bowel disease. The study, published in Nature Microbiology, found that exposure to antibiotics can change the mix of bacterial species in maternal microbes, which are then passed on to their children.
Researchers found that blocking a key protein frees oxygen to damage iron-dependent proteins in lung and breast cancer cells, slowing their growth. The NFS1 protein is crucial for cancer cell survival in high-oxygen environments, but its inhibition may offer a new treatment option.
Researchers at NYU School of Medicine found that mammalian brains can distinguish between one odor and another in under 100 milliseconds, using fewer nerve signals than previously believed. This groundbreaking study has implications for our understanding of human olfaction and the potential for new treatments for smell disorders.
A new study concludes that extended-release naltrexone and buprenorphine-naloxone are equally safe and effective in curtailing opioid use, relapse, treatment drop-out, and overdose. Researchers found similar 24-week relapse rates for both medications, with craving for opioids lower in the naltrexone group.
Researchers at NYU School of Medicine discovered that infliximab blocks TNF-alpha, reducing inflammation in the gut and preventing transplant rejection. They also found that stimulating ATG16L1 protects against TNF-alpha driven inflammation.
A new study suggests that many pelvic tumors in women may have a common origin in the fallopian tubes, which could lead to new strategies for preventing and early detecting ovarian cancer. The research found that ovarian cancer cells share genetic similarities with cells covering the tips of fallopian tubes.
A study published in Science Advances found that mice born by C-section gained an average of 33% more weight than those born vaginally over the course of 15 weeks after weaning. The researchers also discovered significant differences in bacterial species in their guts, with mice born by C-section having a less mature microbiome structure.
Researchers at NYU School of Medicine discovered that calcium flow into cells controls the activation of genes involved in glucose metabolism, enabling T cells to multiply. The study's findings have implications for autoimmune diseases and may lead to new treatments.
A study found that mutations in the KEAP1 gene make lung adenocarcinoma cells vulnerable to oxidative stress, allowing an experimental drug called CB-839 to stop tumor growth. The discovery could lead to a more effective treatment for patients with combined KRAS and KEAP1 mutations.
A study led by NYU Langone Health found that removing a 2mm margin from suspicious moles can completely remove cancer cells with a single procedure. Researchers monitored patients for over a year and found no further suspicious growths, with 90% of biopsied moles being completely removed.
Researchers found significant reductions in fatigue severity in people with MS who underwent transcranial direct current stimulation. The treatment, which is non-invasive and can be delivered remotely, showed promise in improving fatigue levels and quality of life for patients.
A study by NYU Langone Health found that a higher-dose, shorter form of radiation is safe and effective for breast cancer patients under 50, with no increased risk of late side effects. The new technique also yields good to excellent long-term cosmetic results in 92% of patients.
Researchers found that female mice brain structures organize sex and aggressive behavior differently, with separate cell groups controlling each. In contrast, male mice brain circuits overlap in controlling both behaviors, suggesting a fundamental difference in brain organization between sexes.
New research from NYU Langone Health links wireless food stamp transactions to the buying of more healthy foods by people with low incomes. On average, SNAP beneficiaries purchased 5.4 more cups of fruits and vegetables when using EBT-equipped vendors compared to similar shoppers who paid with cash.
A new study led by NYU School of Medicine found that Hispanic and Asian women in Manhattan have a higher prevalence and severity of lupus than white women. The study also showed significant disparities in kidney disease among these demographic groups.
Children who lived near the World Trade Center on 9/11 are showing early signs of increased risk for future heart disease due to exposure to toxic chemicals. Blood tests revealed elevated levels of artery-hardening fats in their blood, linked to higher blood levels of perfluoroalkyl substances (PFASs).
A new study reveals consistent correlations between white matter structural patterns and autistic symptoms in both ASD and ADHD, highlighting potential shared disease mechanisms. The study's findings suggest that biomarkers could guide more specific diagnostic tests and treatments.
Researchers have designed a new kind of antibody that targets toxic protein structures common to Alzheimer's disease, Parkinson's disease, and related conditions. The study demonstrates the effectiveness of these antibodies in removing toxic forms without triggering immune toxicity.
A study found that vitamin C activated the enzyme TET2 in mice with genetic mutations that reduce its function, leading to the death of leukemia stem cells. High-dose vitamin C treatment was also shown to suppress the growth of cancer stem cells from human patients implanted in mice.
Researchers genetically engineered ants to lack their sense of smell, finding they couldn't communicate, forage or compete for queen status. This discovery promises to advance understanding of social communication and its relation to human disorders like autism and depression.
Exposure to air pollution during the first two trimesters of pregnancy has been shown to increase risk for preterm birth and low birth weight. The study's findings also suggest that exposure to fine particulate matter (PM2.5) can lead to decreased body length, placental weight, and anogenital distance.
A new community-based program using patient navigators in barbershops has been shown to increase early detection of colorectal cancer among black men. The study found that participants who received help were twice as likely to get screened, compared to those who did not receive extra support.
Researchers found that inhibiting the partnership between Tregs and dendritic cells might lead to effective immunotherapy for pancreatic cancer. Blocking this relationship may enable the immune system to target pancreatic tumor cells more effectively, potentially slowing tumor growth.
A randomized trial found that combining a specific care management program with memantine significantly improves daily function in Alzheimer's patients. The study shows that the medication plus care program patient group tested 7.5 times higher than the medication-only group.
The City Health Dashboard is a nationwide expansion of an innovative health data visualization tool, enabling hundreds of US cities to accurately identify their most pressing health needs. The dashboard provides 26 key measures of health and drivers of health status at the neighborhood level.
A study published in the Journal of Clinical Investigation reveals a mechanism to reverse disease in arteries by targeting an immune reaction. Researchers at NYU Langone Health discovered that certain immune cells can switch from promoting inflammation to healing, which can lead to reduced plaque growth and improved cardiovascular health.
A comprehensive review of rapidly changing data identified four neural-behavioral models associated with PTSD, pinpointing specific circuits in the brain that mediate between chemical changes and behavioral expressions. The study provides detailed tables to help healthcare providers recognize signs and symptoms of PTSD for diagnosis.
A study published in the Journal of Graduate Medical Education found that transgender actors can effectively teach new doctors to provide sensitive care. The researchers used standardized patients, including a transgender actress, to assess residents' communication skills and patient satisfaction. The results showed that the training a...
The immunotherapy drug pembrolizumab has been shown to shrink tumors in patients with metastatic triple negative breast cancer, regardless of prior treatment. In a Phase II clinical trial, the drug demonstrated activity in both PD-L1-positive and -negative tumors.
In a large-scale randomized clinical trial, cannabidiol reduced seizure frequency by 39% in patients with Dravet syndrome. The study included 120 children and adolescents aged 2-18 years, who received either CBD or placebo over a 14-week period.
Researchers found that chronic pain distorts the intensity of pain perception in other body parts by rewiring circuits in the anterior cingulate cortex. This causes a greater reaction to painful stimuli throughout the body, with far-reaching consequences for mental health and disease treatment.
Researchers analyzed data from large-scale studies of erectile dysfunction medication users and found an overall 11% increase in melanoma risk. However, they attribute the increased risk to detection bias rather than a direct cause-and-effect link between medications and melanoma.
A study published in Nature Medicine found that immune reactions to viruses can disrupt brain connections, leading to learning problems. The research team identified CX3CR1highLY6Clow monocytes as the key players in this process, releasing inflammatory signaling protein TNFα which blocks nerve cell connection formation.
A new study published in Nature Communications suggests that maintaining high levels of adenosine in rats with damaged ACLs prevents osteoarthritis. Adenosine replacement therapy could potentially delay the onset of osteoarthritis and joint replacements.
A new study published in Nature finds that the thalamus strengthens connections within the prefrontal cortex, enabling it to focus attention and make decisions. This discovery has implications for understanding cognitive deficits in diseases such as schizophrenia and improving cognition by adjusting thalamic function.
A study by NYU Langone Health found that 3.4% of US adults suffer from serious psychological distress, with 9.5% lacking health insurance and 10.5% experiencing delays in getting professional help. The research suggests a worsening mental health crisis despite increased access to care since the ACA.
Researchers observed lower body mass index (BMI) and blood pressure among low-income individuals living in the city's noisiest neighborhoods. The study suggests that neighborhood noise may have an indirect impact on health, potentially due to increased physical activity resulting from walkability.
Researchers at NYU Langone Health have uncovered a critical pathway by which pancreatic cancer cells evade the immune system, involving high levels of two proteins - dectin-1 and galectin-9. The study found that blocking this interaction can increase survival in mice with pancreatic tumors.
A surgical technique has been shown to decrease the severity of tics in young adults with severe Tourette syndrome by an average of 50%. The study, published in Journal of Neurosurgery, adds evidence supporting deep brain stimulation as a safe and effective treatment for severe cases.
Researchers have developed two new blood tests that can reliably detect previously unidentifiable forms of melanoma, a type of aggressive skin cancer. The tests use DNA fragments in the blood to monitor tumor growth and can detect changes in genes that help cancer cells multiply.
A new study found that patients with spinal deformity are at greater risk for dislocation or revision surgery after hip replacement. The researchers analyzed 107 patients with sagittal spinal deformity who underwent 139 hip replacements, finding an 8% dislocation rate and a 5.8% revision surgery rate.
Smokers who enrolled in a smoking cessation program before surgery had fewer adverse events and better surgical outcomes, including lower hospital readmission rates. The study found that the program reduced the risk of complications by 4.3 times and decreased reoperation rates.
The study provides recommendations to optimize decision-making for medical imaging in pediatric orthopedic care, highlighting the risk of cancer and genetic defects from radiation exposure. Best practices to reduce radiation include limiting precise collimation, fluoroscopy bursts, and utilizing low-dose CT protocols.
Researchers analyzed 57 tissue samples from women with uterine carcinosarcoma and found that the tumors share some genetic traits but also exhibit great diversity. This diversity makes it challenging to find effective treatments for the cancer, which has a low survival rate.
A global research team, led by NYU Langone's Jef Boeke, has built five new synthetic yeast chromosomes, replacing 30% of the organism's genetic material. The breakthrough enables the creation of designer genomes to address unmet needs in medicine and industry.
A study found that the drug everolimus protects ovaries from cyclophosphamide, a common chemotherapy used against breast cancer, which depletes egg cells needed to achieve pregnancy. Female mice treated with everolimus and chemotherapy had more than twice as many offspring as those treated with chemotherapy alone.
A team of neuroscientists has found that somatostatin-expressing (Sst) interneurons play a key role in controlling the flow of information in the brain. The researchers discovered that these cells operate like a switchboard, selectively blocking or encouraging the flow of information to help animals make informed decisions and guide th...
Researchers developed an assay to detect autoantibodies present in rheumatoid arthritis patients, finding that memory B cells secrete these molecules. The study suggests targeting these immune system cells could lead to a cure for the disease.
A new study published in Neuromodulation found that transcranial direct current stimulation (tDCS) combined with computer games significantly improved cognitive measures in patients with multiple sclerosis. The treatment showed greater gains in complex attention and response times compared to those who played computer games alone.