A new study found that a gene-based blood test can accurately monitor treatment progress in people with late-stage melanoma, allowing for swift treatment modification and potentially saving lives. The test targets the most common mutations in melanoma cells, detecting DNA fragments released by dying tumor cells.
A new study by NYU Langone Health found that New York City's subway system has the highest airborne particle concentration, with some stations reaching up to 77 times the typical outdoor air quality. The study measured air quality in 71 stations across four cities and found that even cleaner neighborhoods struggle with pollutants.
A study found that surgery to repair an inflamed gut may trigger a second immune system attack, which could lead to pouchitis. Researchers analyzed tissue samples and gene activity in patients who developed pouchitis after J-pouch surgery.
A new study finds that people with schizophrenia are almost three times more likely to die from COVID-19 than those without the mental disorder. The study, led by researchers at NYU Langone Health, shows that schizophrenia is the biggest risk factor for death after age, with a 2.7-fold increased odds of dying.
A new study provides the first national estimate of systemic lupus erythematosus in the US, finding that approximately 72.8 out of every 100,000 people nationwide have the condition, which affects mostly women and disproportionately affects certain ethnic groups.
A recent study found that transmembrane protein 41 B (TMEM41B) is essential for SARS-CoV-2 replication. The researchers used CRISPR to inactivate genes in human cells infected with the virus and discovered that TMEM41B was the only molecular feature common to both flaviviruses and coronaviruses, including SARS-CoV-2.
A study by NYU Langone Health found that once hospitalized, Black patients with COVID-19 have better outcomes than White patients. The research controlled for comorbid conditions and neighborhood income.
A new study uses artificial intelligence to predict which patients with metastatic melanoma will respond well to immune checkpoint inhibitors. The algorithm achieves an accuracy rate of 80%, outperforming current predictive tools in a significant way.
A new study by NYU Langone researchers found that tenant exposure to secondhand smoke in NYCHA buildings has not declined despite a smoking ban implemented one year ago. The policy requires more intensive efforts to support and enforce the rule, including better training for building managers and resident education.
Pancreatic cancer cells use nerve growth factor to signal nerves to grow into dense tumors and secrete nutrients like serine. This allows the cancer cells to multiply despite nutrient starvation, highlighting a unique adaptation that contributes to their deadliness.
A new mapping tool for analyzing tissue damage seen on MRI brain scans accurately detects early signs of cognitive decline, correlating with worsening dementia and other brain-damaging conditions. The tool offers a standardized method for calculating the volume and location of white matter lesions in the brain.
A new analysis revealed that New York City's COVID-19 outbreak began in late February with at least 109 different sources seeding chains of infection. The study found that over 40% of people who tested positive had no known contact with another infected person before contracting the virus.
A new study shows that COVID-19 death rates have dropped in New York due to a shift towards younger, healthier patients and improved healthcare practices. The study found that patients with chronic conditions were less likely to be hospitalized, and those who were treated earlier received better care.
A large American study found that pregnant mothers with low thyroid hormone levels are more likely to have children with attention deficit/hyperactivity disorder (ADHD). The study of 329,157 children showed that Hispanic children born to hypothyroid mothers were at highest risk.
A new study finds that focal epilepsy, affecting one in 26 American adults, is often overlooked due to subtle symptoms. Early diagnosis can lead to fewer car accidents, with the researchers estimating 1,816 preventable accidents annually worldwide.
A new study shows that COVID-19 can cause neurological injuries in approximately one in seven infected patients. These injuries range from temporary confusion due to low oxygen levels to stroke and seizures in the most serious cases, significantly raising a patient's risk of dying while still in hospital.
A new study published in Nature shows that rodents rely on a combination of innate instincts and learning to recognize unique infant cries. Experienced caregivers were found to be more effective at identifying subtle variations in distress calls and retrieving crying pups, while inexperienced animals required extensive training.
Most adults with systemic lupus erythematosus (SLE) and common forms of arthritis are not at increased risk of hospitalization from COVID-19, despite taking immunosuppressive medications. Hospitalization rates for these groups are similar to those for the general population.
A new study found that yoga significantly improved symptoms for those with generalized anxiety disorder, but not as effective as cognitive behavioral therapy. Yoga was more effective than stress management, with 54% of participants experiencing improved symptoms compared to 33% in the control group.
Research published in Journal of Child Psychology and Psychiatry suggests that obesity in pregnant women can affect the developing brain, particularly in areas responsible for decision-making and behavior. The study used fetal brain activity measurements to identify potential links between maternal BMI and changes in brain connectivity.
A new study has pinpointed the five most likely causes of post-traumatic stress in police officers, highlighting the importance of genetic and emotional differences. The research identified specific causal factors, including a tendency to startle easily, anxiety, depression, and genetic mutations, which can contribute to the developmen...
A new study from NYU Langone Health suggests that injecting adenosine into joints can stimulate cartilage growth and prevent disease progression. The treatment has shown promising results in animal models of osteoarthritis, with regrowth rates of up to 50%.
A new study by NYU Langone Health found that women receiving standard treatment for ovarian, uterine, and cervical cancers are not at increased risk of hospitalization or death from COVID-19. In fact, 75% of gynecologic cancer patients with COVID-19 had a mild form of the disease and recovered
A new study has uncovered 12 proteins linked to both tau and Alzheimer's disease, expanding understanding of the molecular interactions driving neurodegeneration. The research analyzed donated brain tissue samples from individuals with Alzheimer's, revealing dozens of other proteins associated with the disease.
Researchers found that non-white counties had higher cumulative incidences and deaths compared to predominantly white counties, even among high-income communities. Structural racism may explain the racial disparities in COVID-19 cases and deaths noted in Black counties.
Two groups of nerve cells in the posterior amygdala regulate emotions and drive male social behaviors like sex and aggression. Blocking signals from these neurons impairs males' ability to mate, while boosting them increases aggression.
A set of reviews concludes that hundreds of studies link widespread health issues including infertility, diabetes, and impaired brain development to hormone disruptors in pesticides, flame retardants, and certain plastics.
A new study from NYU Grossman School of Medicine researchers shows that the antimalarial drug hydroxychloroquine significantly reduces the incidence of congenital heart block (CHB) in newborn babies, a rare and sometimes fatal condition. CHB affects as many as one in 15,000 live births and is strongly linked to immune proteins in mothers.
A new study published in Nature Medicine found that breast cancer patients who experience a heart attack have a higher risk of cancer recurrence, spread, and death. The research suggests that heart attacks can trigger an immune reaction that makes it easier for cancer cells to grow.
A new NYU study found that exercising in nearby parks reduces anxiety and depression, but safety concerns prevent many from using them. The researchers suggest improving park lighting, programs, and community engagement to make parks feel safer.
A new study by NYU Langone Health found that commercially available fireworks emit toxic metals such as lead, copper, and titanium, which can damage human cells and animal lungs. Exposure to these particles was also linked to increased oxidation in the body, a chemical process that can cause cell damage.
Researchers at NYU Langone Health have developed a new vaccination strategy that targets the toxic molecules released by Staphylococcal bacteria, including MRSA, to prevent deadly infections. In a study published in the Journal of Experimental Medicine, mice vaccinated with this experimental vaccine demonstrated an immune response and ...
A new study in rodents suggests that star-shaped brain cells called astrocytes may be responsible for killing nerve cells in glaucoma. The study found that increased pressure drove astrocytes to release toxins that killed neurons, highlighting a potential target for treating the disease.
Researchers have decoded the brain's smell-processing center, identifying a code for converting sensory information into perception. By manipulating nerve signaling, they found changes in glomeruli activation led to significant drops in odor recognition accuracy, with timing and order crucial for correct detection.
The American Medical Directors Association published recommendations to reduce COVID-19 spread in nursing homes and long-term care facilities. The guidelines include COVID-specific units, daily screenings, and staff testing to prevent outbreaks.
A new analysis found that fewer people with COVID-19 suffer from stroke compared to previous reports. However, strokes in patients with the virus tend to be more severe and have poorer outcomes.
Research at NYU Langone Health found a link between elevated blood levels of toxic chemicals and an increased risk for celiac disease in young people. Young females were eight times more likely to become gluten intolerant, while males were twice as likely with fire-retardant exposure.
A study of 12,594 patients found that common high blood pressure drugs did not increase the risk of contracting or developing severe COVID-19. The research suggests that these medications can be safely used in patients with COVID-19 disease.
A study by NYU Langone Health shows a massive expansion of telemedicine during the COVID-19 pandemic, with virtual urgent care visits growing by 683% and non-urgent virtual care visits increasing by 4,345%. The rapid growth was made possible by US insurers expanding coverage and state licensing relaxations.
Researchers found that pancreatic cancer cells use autophagy to degrade MHC-I proteins, making them resistant to immunotherapies. Blocking autophagy or using drugs like chloroquine enhances MHC-I expression on the surface of cancer cells, increasing their susceptibility to immunotherapy.
Researchers found that structural changes in protein bundles called chromosomes affect access to genes in T cell acute lymphoblastic leukemia. The new work shows that altering the 3D architecture of chromosomes can trigger cancer growth and spread, making targeted therapy a promising approach.
Death rates from metastatic melanoma dropped by nearly 18 percent between 2013 and 2016, thanks to new therapies that harness the immune system or target specific gene mutations. These advances in treatment have led to the largest yearly declines in deaths due to melanoma ever recorded.
Researchers at NYU Langone Health discovered a cell defense mechanism that uses tiny, protein-coated packages called exosomes to bind to and neutralize bacterial toxins. This 'soaking up' of toxins helps keep cells safe from infection.
A US population-based study found that medication treatment for opioid use disorder significantly reduces fatal overdose risk. Patients receiving treatment with opioid agonists had an 80% lower risk of dying from an opioid overdose compared to those without medication.
A comprehensive molecular study has defined key genes and proteins contributing to endometrial cancer. The research suggests tailored treatments for each patient and potential biological targets for future drug design.
Recent clinical trials of Prolonged Exposure Therapy and Cognitive Processing Therapy show limited effectiveness in treating active duty military personnel and veterans with PTSD. The studies suggest that emotionally demanding therapies may not be beneficial for all patients, and more personalized treatment approaches are needed to acc...
Sperm cells activate 90% of their genes, a pattern seen in other species, to repair DNA before passing it to the next generation. This process may influence the evolution of specific genes, with unexpressed genes containing fewer DNA code errors.
Researchers at NYU Langone Health have discovered a new role for circular RNA in regulating the spread of melanoma cancers. The study found that CDR1as blocks the aggressive growth of cancer cells, while its loss promotes it. Higher levels of CDR1as were linked to increased survival rates among patients with melanoma.
A new study found that Medicaid expansion was associated with a six percent lower rate of total opioid overdose deaths, as well as lower rates of death involving heroin and synthetic opioids. However, unexpectedly, an 11 percent increase in methadone overdose mortality was observed with Medicaid expansion.
Researchers found that pancreatic tumor cells secrete interleukin-1β (IL-1β) to reduce anti-cancer immune responses, promoting PDA tumor growth. Blocking IL-1β with an antibody treatment doubled T cell infiltration and increased PD-1 blockade efficacy by 40%.