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NYU Langone Health / NYU Grossman School of Medicine


Hair growth drug safe at low doses for breast cancer patients

A study suggests that low doses of the commonly prescribed hair loss treatment minoxidil are safe and effective for regrowing hair in most breast cancer patients. The researchers found that all participants who took a low dose of oral minoxidil saw improvements in hair growth or stabilization within three to six months.

SourceNYU Langone Health / NYU Grossman School of Medicine·JournalJournal of the American Academy of Dermatology·TypeObservational study·DateDec 9, 2024

Brain mapping advances understanding of human speech and hallucinations in schizophrenia

Researchers mapped auditory corollary discharge signals in the brain's motor cortex to better understand human speech and hallucinations in schizophrenia. Disruptions to this system are thought to be hallmarks of auditory hallucinations, offering a new explanation for the source of these symptoms.

SourceNYU Langone Health / NYU Grossman School of Medicine·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateDec 3, 2024

Study details how cancer cells fend off starvation and death from chemotherapy

Researchers at NYU Langone Health discovered two ways cancer cells evade chemotherapy's effects: by slowing down pyrimidine synthesis and activating anti-apoptotic proteins. This better understanding could lead to more effective combination therapies and diagnostic tests, ultimately improving patient outcomes.

SourceNYU Langone Health / NYU Grossman School of Medicine·JournalNature Medicine·TypeExperimental study·DateNov 26, 2024

Remote telemedicine tool found highly accurate in diagnosing melanoma

A new study found that a remote telemedicine tool called SpotCheck is highly accurate in diagnosing melanoma, with experts able to remotely examine skin lesions using dermoscopy. The tool has the potential to address diagnostic and treatment disparities for lower-income populations with limited access to dermatologists.

SourceNYU Langone Health / NYU Grossman School of Medicine·JournalJournal of the American Academy of Dermatology·TypeRandomized controlled/clinical trial·DateNov 14, 2024

While more is better, even moderate amounts of exercise may reduce risk for common heart condition

A new study found that even moderate amounts of exercise can reduce the risk of atrial fibrillation, a common heart condition. The research, led by NYU Langone Health, used data from over 6,000 participants and showed that those with higher physical activity levels had a lower risk of developing the condition.

Kidney transplantation among those with HIV infections shown safe and effective

A new study found that kidney transplantation from HIV-positive donors to recipients with HIV is safe and effective, with comparable survival rates and risks of serious side effects. The study's results support the use of organs from HIV-positive donors as standard clinical practice for people with HIV in need of kidney transplantation.

SourceNYU Langone Health / NYU Grossman School of Medicine·JournalNew England Journal of Medicine·TypeObservational study·DateOct 16, 2024

Accelerated three-year medical school students perform as well as peers in traditional four-year programs

A new study by NYU Langone Health found that graduates of an accelerated three-year MD program performed equally well on tests of skill and knowledge as their peers who followed a traditional four-year program. The study showed that students in the accelerated program scored comparably on metrics taken during medical school and residen...

Adding vagus nerve stimulation to training sessions may boost how well sounds are perceived

Researchers found that vagus nerve stimulation can improve sound discrimination in mice, suggesting a potential new approach to treating hearing disorders. The technique may also speed up hearing improvements from cochlear implants, enabling implant recipients to communicate more effectively.

SourceNYU Langone Health / NYU Grossman School of Medicine·JournalNature Neuroscience·TypeExperimental study·DateOct 9, 2024

Breastfeeding is crucial to shaping infant’s microbes and promoting lung health

A new study shows that breastfeeding beyond three months supports the gradual maturation of a baby's microbiome, which lowers their risk of developing asthma. The study found that breast milk regulates the mix of microbes in infants, setting the pace and sequence for microbial colonization.

SourceNYU Langone Health / NYU Grossman School of Medicine·JournalCell·TypeRandomized controlled/clinical trial·DateSep 19, 2024

RECOVER study determines most common long COVID symptoms in children and teens

A new measure identifies school-age children and adolescents with the highest chances of having Long COVID based on long-term symptoms. Researchers found that prolonged symptoms affect almost every organ system, with distinct patterns in children and teens, highlighting the need for further study and monitoring.

SourceNYU Langone Health / NYU Grossman School of Medicine·JournalJournal of the American Medical Association·TypeExperimental study·DateAug 21, 2024

Blood platelet score detects previously unmeasured risk of heart attack and stroke

Researchers developed a new platelet-centric scoring system to predict platelet hyperreactivity and cardiovascular events. The Platelet Reactivity ExpresSion Score (PRESS) can detect hyperreactive platelets in patients at imminent risk of heart attack and healthy individuals with unknown future risk.

SourceNYU Langone Health / NYU Grossman School of Medicine·JournalNature Communications·TypeExperimental study·DateAug 20, 2024

Distinct pattern in protein production can predict severe side effects from skin cancer treatment

Researchers found that a specific pattern of gene activity can predict which melanoma patients are likely to experience severe side effects from immunotherapy. The study identified a heightened gene signature, known as the spleen tyrosine kinase pathway, as the key indicator of increased risk.

SourceNYU Langone Health / NYU Grossman School of Medicine·JournalClinical Cancer Research·DateAug 8, 2024

Patients in hospitals that provide inpatient addiction services were more likely to start and continue lifesaving medication for opioid use disorder treatment after discharge

A new study found that patients in hospitals with specialized addiction consult services were more likely to start and continue lifesaving medication for opioid use disorder treatment after discharge. The CATCH program, a hospital-based intervention, showed promising results in increasing treatment initiation and retention rates compar...

SourceNYU Langone Health / NYU Grossman School of Medicine·JournalJAMA Internal Medicine·DateJul 29, 2024

AI tool successfully responds to patient questions in electronic health record

A new study by NYU Langone Health shows that an AI tool can draft responses to patients' EHR queries as accurately as human healthcare professionals, with greater perceived empathy. The tool has the potential to dramatically reduce physicians' In Basket burden while improving their communication with patients.

SourceNYU Langone Health / NYU Grossman School of Medicine·JournalJAMA Network Open·TypeExperimental study·DateJul 16, 2024

New technique reveals earliest signs of genetic mutations

Researchers developed a new technique called HiDEF-seq to detect early molecular changes in DNA code that precede mutations. The study found higher numbers of single-strand DNA changes in healthy cells from people with genetic syndromes linked to cancer, suggesting a link between these changes and the development of cancer.

SourceNYU Langone Health / NYU Grossman School of Medicine·JournalNature·TypeExperimental study·DateJun 12, 2024

Adding nurse case managers to telehealth significantly lowers blood pressure in Black and Hispanic stroke survivors

Low-income Black and Hispanic stroke survivors with uncontrolled hypertension experienced a more than two-fold reduction in blood pressure when tracked at home and sent readings to a nurse. Nurse case management enhanced telehealth programs showed significant benefits for this vulnerable population.

Studies reveal cell-by-cell changes caused when pig hearts and kidneys are transplanted into humans

Researchers analyzed cell changes before, during, and after xenotransplantation surgeries using single-cell RNA sequencing. The study found evidence of subtle immune reactions that could cause xenotransplants to fail over time, including antibody-mediated rejection and tissue repair mechanisms.

SourceNYU Langone Health / NYU Grossman School of Medicine·JournalMed·TypeExperimental study·DateMay 21, 2024

Artificial intelligence tool detects sex-related differences in brain structure

A new study using AI technology analyzed MRI scans from 471 men and 560 women, revealing differences in brain organization at a cellular level. The findings highlight the need for diversity in neurological research and may offer new insights into how psychiatric and neurological disorders develop differently in men and women.

SourceNYU Langone Health / NYU Grossman School of Medicine·JournalScientific Reports·TypeImaging analysis·DateMay 14, 2024

First-ever combined heart pump and pig kidney transplant gives new hope to patient with terminal illness

A combined mechanical heart pump and gene-edited pig kidney transplant has given new hope to a patient with heart and kidney failure. The surgery was performed in two stages, first implanting the heart pump and later transplanting the gene-edited pig kidney. This innovative approach has shown promise for patients who would otherwise no...

Brain recordings in people before surgery reveal how all minds plan what to say prior to speaking

A new study reveals that pauses in speech can provide information about how people's brains plan and produce speech. The research found that neighboring brain regions play a crucial role in speech planning, with longer latencies corresponding to planning and shorter latencies indicating physical mechanics of speaking.

SourceNYU Langone Health / NYU Grossman School of Medicine·JournalBrain·TypeExperimental study·DateMar 19, 2024

​​​​​​​Study links key gene to protection from severe illness and death from Covid infections in men under age 75

A genetic analysis of hospitalized Covid-19 patients found that a certain IL1RN variant protects men under age 75 from severe illness and death. The study showed that the protective gene variant, rs419598, is associated with lower inflammation and reduced mortality in men up to age 74.

SourceNYU Langone Health / NYU Grossman School of Medicine·JournalThe Journal of Infectious Diseases·TypeObservational study·DateMar 13, 2024

“Double life” of key immune protein reveals new strategies for treating cancer and autoimmune diseases

Researchers discover that PD-1 forms dimers to function optimally, and manipulating its dimerization can enhance or inhibit T cell activity. This finding offers new insights into developing more effective cancer immunotherapies and treatments for autoimmune diseases.

SourceNYU Langone Health / NYU Grossman School of Medicine·JournalScience Immunology·TypeExperimental study·DateMar 8, 2024

Synthetic DNA sheds light on mysterious difference between living cells at different points in evolution

A new study uses synthetic DNA to show that yeast and mammalian cells have distinct transcription patterns, with yeast constantly transcribing genes and mammalian cells repressing them. The findings could help understand the functions of non-gene-related transcription and guide engineering of yeast for new medicines or gene therapies.

SourceNYU Langone Health / NYU Grossman School of Medicine·JournalNature·TypeExperimental study·DateMar 6, 2024

AI can speed design of health software

A new study finds that generative AI can accelerate the design of healthcare software, particularly for complex medical problems like diabetes prevention. Researchers at NYU Langone Health used ChatGPT to develop a personalized automatic messaging system in over 40 hours, compared to 200 programmer hours with non-AI enabled efforts.

SourceNYU Langone Health / NYU Grossman School of Medicine·JournalJournal of Medical Internet Research·TypeCase study·DateMar 6, 2024

Plant-based diet tied to improved sexual health in men treated for prostate cancer

A study of over 3,500 men with prostate cancer found that a plant-based diet significantly improved measures of sexual function, urinary health, and vitality scores. The research suggests that adding more fruits and vegetables to the diet while reducing meat and dairy can have a positive impact on quality of life.

SourceNYU Langone Health / NYU Grossman School of Medicine·JournalCancer·TypeObservational study·DateFeb 13, 2024

Police seizures of psychedelic drugs are soaring throughout the United States

Seizures of psilocybin, a hallucinogenic compound found in psychedelic mushrooms, have surged by 369% across the US since 2017, according to a new study. The highest number of seizures were recorded in the Midwest and West regions, with nearly quadrupled amounts of seized drugs.

SourceNYU Langone Health / NYU Grossman School of Medicine·JournalDrug and Alcohol Dependence·TypeData/statistical analysis·DateFeb 6, 2024

Gene-based therapy may slow development of life-threatening heart condition

Researchers have found that a gene-based therapy targeting plakophilin-2 can interrupt the progression of arrhythmogenic right ventricular cardiomyopathy, a rare inherited disorder. The treatment reduced episodes of arrhythmia and slowed the deterioration of the heart's walls in mice.

SourceNYU Langone Health / NYU Grossman School of Medicine·JournalCirculation Genomic and Precision Medicine·TypeExperimental study·DateJan 30, 2024