A new study shows that anti-obesity drugs, including GLP-1 agonists, are safe and effective in treating type 2 diabetes in kidney transplant recipients. The medications were found to reduce the risk of organ failure and death, but also increase the risk of diabetic retinopathy.
A new study in rodents reveals that oxytocin can delay an embryo's development for days to weeks after conception, a phenomenon known as diapause. This finding may offer new insights into pregnancy and fertility issues faced by humans.
Researchers developed Ultra-Rapid droplet digital PCR to quickly identify genetic mutations in brain tumors, enabling accurate removal during surgery. The tool can detect small numbers of cancer cells and has the potential to become a practical tool for real-time detection during brain surgery.
Researchers at NYU Langone Health identified a new direct feedback loop in the brain that mixes sensory information, memories, and emotions to label sights and sounds as more important. This discovery may lead to new solutions for problems like post-traumatic stress disorder and autism.
Researchers analyzed over 1.1 million pregnancies in Denmark to investigate potential links between a mother's health conditions and her child's risk of autism. They found that most reported associations can be explained by factors such as genetics, exposure to pollution, and access to healthcare.
Researchers at NYU Langone Health found that dopamine, a brain chemical linked to male aggression, grows less important in promoting aggression as males gain fighting experience. In contrast, females show no response to manipulated dopamine levels, suggesting a distinct role for the chemical in female aggression.
The study estimates that half a million new cases of dementia will be reported annually by 2060, with the risk of developing dementia after age 55 being 42% among Americans. The increasing number of cases is linked to aging, genetic factors, and lifestyle choices such as hypertension, diabetes, obesity, and poor mental health.
Researchers found that declining levels of two molecules in the blood, acetyl-L-carnitine and free carnitine, track closely with worsening Alzheimer's disease. The study suggests these biomarkers could identify those at risk and potentially diagnose early dementia.
A new study reveals that the vestibulo-ocular reflex, which enables stable perception of surroundings, matures without sensory input in newborns. Researchers discovered that the slowest-maturing part of the brain circuit is at the neuromuscular junction, not in the brain as previously assumed.
Two studies suggest that psilocybin-assisted psychotherapy can improve mental health outcomes for patients with cancer and alcohol use disorder, reducing symptoms of anxiety, depression, and obsessive thoughts, while also promoting lasting personality changes.
A recent study found that multiple phage species can coexist stably on a genetically uniform strain of E. coli in the human gut. The researchers discovered that each phage species prefers slower or faster growing cells, allowing them to find a separate niche and maintain stable coexistence.
A new study finds that caregiving stress in younger Black women is associated with an increased risk of developing hypertension. The research team followed the health of more than 3,500 Black adults and found that those reporting moderate or high caregiving stress were more likely to develop hypertension.
A study suggests that low doses of the commonly prescribed hair loss treatment minoxidil are safe and effective for regrowing hair in most breast cancer patients. The researchers found that all participants who took a low dose of oral minoxidil saw improvements in hair growth or stabilization within three to six months.
Researchers used AI on CT scans originally meant for tumors to detect calcium buildup in arteries, a sign of worsening cardiovascular disease. The study found that this opportunistic screening could predict heart attacks or other cardiovascular events with high accuracy.
Researchers mapped auditory corollary discharge signals in the brain's motor cortex to better understand human speech and hallucinations in schizophrenia. Disruptions to this system are thought to be hallmarks of auditory hallucinations, offering a new explanation for the source of these symptoms.
Researchers found that certain cancer treatments, such as immune checkpoint inhibitors, can trigger damaging levels of inflammation in the heart and increase risk of heart disease. This is because these treatments interfere with immune regulation in the heart's largest blood vessels.
Researchers at NYU Langone Health discovered two ways cancer cells evade chemotherapy's effects: by slowing down pyrimidine synthesis and activating anti-apoptotic proteins. This better understanding could lead to more effective combination therapies and diagnostic tests, ultimately improving patient outcomes.
The surgical team led by Stephanie H. Chang performed the groundbreaking procedure using da Vinci Xi robotic system at NYU Langone Transplant Institute. The successful transplant marks a significant milestone in lung transplantation surgery, offering hope to patients with chronic obstructive pulmonary disease (COPD) like Cheryl Mehrkar.
A new study found that a remote telemedicine tool called SpotCheck is highly accurate in diagnosing melanoma, with experts able to remotely examine skin lesions using dermoscopy. The tool has the potential to address diagnostic and treatment disparities for lower-income populations with limited access to dermatologists.
A new study found that even moderate amounts of exercise can reduce the risk of atrial fibrillation, a common heart condition. The research, led by NYU Langone Health, used data from over 6,000 participants and showed that those with higher physical activity levels had a lower risk of developing the condition.
Researchers at NYU Langone Health develop antibodies that selectively target mutant HER2 cancer protein without harming healthy cells. The new treatment, a bispecific T cell engager, shows promise in reducing tumor growth with minimal side effects.
A new study found that long-term, low-dose valacyclovir treatment significantly reduces the risk of vision-damaging bouts of inflammation and infection in patients with shingles. Participants treated for a year saw a 26% reduction in eye disease flare-ups at 18 months.
A new study found that kidney transplantation from HIV-positive donors to recipients with HIV is safe and effective, with comparable survival rates and risks of serious side effects. The study's results support the use of organs from HIV-positive donors as standard clinical practice for people with HIV in need of kidney transplantation.
A new study by NYU Langone Health found that graduates of an accelerated three-year MD program performed equally well on tests of skill and knowledge as their peers who followed a traditional four-year program. The study showed that students in the accelerated program scored comparably on metrics taken during medical school and residen...
Researchers found that vagus nerve stimulation can improve sound discrimination in mice, suggesting a potential new approach to treating hearing disorders. The technique may also speed up hearing improvements from cochlear implants, enabling implant recipients to communicate more effectively.
Researchers at NYU Langone Health will use visible-light OCT technology to detect biomarkers of neurodegenerative disease, including Alzheimer’s and Parkinson’s diseases. The study aims to identify retinal layers and monitor the effects of therapies.
A new study found that over a dozen bacterial species in the oral microbiome are linked to a 30-50% increased chance of developing head and neck squamous cell carcinoma. The research analyzed data from 159,840 Americans and identified key bacteria that may contribute to the disease.
A new study shows that breastfeeding beyond three months supports the gradual maturation of a baby's microbiome, which lowers their risk of developing asthma. The study found that breast milk regulates the mix of microbes in infants, setting the pace and sequence for microbial colonization.
A study published in JAMA reports on the eye's functioning after a whole-eye transplant, revealing normal pressure and blood flow over time. The transplanted eye has maintained some remaining structure in the retina, offering hope for future sight restoration.
A new study by NYU Langone Health found that the risk of death for kidney donors has decreased significantly since the 1990s, with fewer than one death occurring for every 10,000 donations. Donors who were male and had a history of high blood pressure were more likely to die within 90 days of surgery.
A new measure identifies school-age children and adolescents with the highest chances of having Long COVID based on long-term symptoms. Researchers found that prolonged symptoms affect almost every organ system, with distinct patterns in children and teens, highlighting the need for further study and monitoring.
Researchers developed a new platelet-centric scoring system to predict platelet hyperreactivity and cardiovascular events. The Platelet Reactivity ExpresSion Score (PRESS) can detect hyperreactive platelets in patients at imminent risk of heart attack and healthy individuals with unknown future risk.
A new study identifies three distinct profiles of preterm-born children, revealing markedly different cognitive and behavioral results. The analysis suggests that precision psychiatry can lead to more effective treatment for individual children, highlighting the complexity of preterm birth.
Researchers found that a specific pattern of gene activity can predict which melanoma patients are likely to experience severe side effects from immunotherapy. The study identified a heightened gene signature, known as the spleen tyrosine kinase pathway, as the key indicator of increased risk.
Researchers found a significant spike in fine-particle air pollutant levels after the display, with some areas exceeding 1,000 micrograms per cubic meter, compared to NYC's average daily concentration of 15 micrograms.
A new study found that an AI program generated explanations of heart test results in most cases, with 73% deemed suitable for patients without changes. The AI explanations were also rated as easy to understand by non-clinical participants, reducing worry in many cases.
A new study found that patients in hospitals with specialized addiction consult services were more likely to start and continue lifesaving medication for opioid use disorder treatment after discharge. The CATCH program, a hospital-based intervention, showed promising results in increasing treatment initiation and retention rates compar...
A new study by NYU Langone Health shows that an AI tool can draft responses to patients' EHR queries as accurately as human healthcare professionals, with greater perceived empathy. The tool has the potential to dramatically reduce physicians' In Basket burden while improving their communication with patients.
Researchers developed a new technique called HiDEF-seq to detect early molecular changes in DNA code that precede mutations. The study found higher numbers of single-strand DNA changes in healthy cells from people with genetic syndromes linked to cancer, suggesting a link between these changes and the development of cancer.
A new AI tool developed by NYU Langone Health accurately diagnoses adenocarcinoma lung cancer and predicts its severity and likelihood of return. The tool uses histomorphological features to distinguish between similar lung cancers and predict tumor recurrence with 99% accuracy.
Low-income Black and Hispanic stroke survivors with uncontrolled hypertension experienced a more than two-fold reduction in blood pressure when tracked at home and sent readings to a nurse. Nurse case management enhanced telehealth programs showed significant benefits for this vulnerable population.
Experts at NYU Langone Health have warned of a growing public health threat from hard-to-treat fungal skin infections in the US. Two new reports document cases of highly contagious forms of ringworm and jock itch that can take months to clear up with treatment.
Researchers analyzed cell changes before, during, and after xenotransplantation surgeries using single-cell RNA sequencing. The study found evidence of subtle immune reactions that could cause xenotransplants to fail over time, including antibody-mediated rejection and tissue repair mechanisms.
A new questionnaire assesses sexual health concerns in female partners of prostate cancer patients, highlighting challenges with communication and feelings of isolation. The study reveals high levels of distress and depression among these women.
A new study finds that the interleukin-17 pathway activates hypoxia-inducible factor 1-alpha in psoriasis, leading to increased sugar breakdown and lactate production. Blocking this pathway with an experimental drug may offer a new treatment option for inflammatory skin diseases.
A new study using AI technology analyzed MRI scans from 471 men and 560 women, revealing differences in brain organization at a cellular level. The findings highlight the need for diversity in neurological research and may offer new insights into how psychiatric and neurological disorders develop differently in men and women.
Fentanyl seizures in the US increased by 1,700% between 2017 and 2023, with pills accounting for nearly half of total seizures. The West region saw a significant increase in fentanyl pill seizures, while the South had the highest number of powder form seizures.
A new study reveals that pediatric emergency departments miss signs of epilepsy in two-thirds of cases. Nonmotor seizures, which cause 'zones out' behavior, are often overlooked due to similarities with anxiety and panic attacks.
A combined mechanical heart pump and gene-edited pig kidney transplant has given new hope to a patient with heart and kidney failure. The surgery was performed in two stages, first implanting the heart pump and later transplanting the gene-edited pig kidney. This innovative approach has shown promise for patients who would otherwise no...
Researchers have discovered a mechanism in the brain that determines which memories are consolidated into permanent form during sleep. Sharp wave-ripples, a pattern of neural activity, are believed to be the key 'tagging' system that identifies important experiences and replays them during sleep.