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Rural hospital closures affect operations of surrounding hospitals

A study by Penn State College of Medicine researchers found that rural hospital closures lead to increased strain on nearby hospitals, resulting in higher emergency department visits and admissions. The study analyzed data from over 180 closed rural hospitals and found a significant increase in healthcare burden at bystander hospitals.

SourcePenn State·JournalJournal of Hospital Medicine·DateDec 13, 2022

Changes in Earth’s orbit may have triggered ancient warming event

An international team of scientists found that changes in Earth's orbit may have triggered a rapid global warming event 56 million years ago, known as the Paleocene-Eocene Thermal Maximum. The study suggests that orbital configurations favored hotter conditions and may have played a role in triggering the event.

SourcePenn State·JournalNature Communications·TypeObservational study·DateDec 13, 2022

Researchers propose methods for automatic detection of doxing

Researchers have identified a method that can automatically detect doxing on Twitter with high accuracy, which could help protect users from cyberbullying. The approach uses machine learning to differentiate between self-disclosures and malicious disclosures of sensitive personal information.

SourcePenn State·JournalProceedings of the ACM on Human-Computer Interaction·DateDec 12, 2022

Hummingbird flight could provide insights for biomimicry in aerial vehicles

Researchers used a novel modeling method to study hummingbird wing movement, revealing previously unknown principles of actuation. They found that hummingbirds' primary muscles pull wings in three directions: up and down, back and forth, and twisting. This discovery has implications for technological development of agile aerial systems.

SourcePenn State·JournalProceedings of the Royal Society B Biological Sciences·TypeObservational study·DateDec 12, 2022

Rare cosmic explosion blasts hole in established science

A blast of high-energy light from a galaxy 1 billion light-years away challenges long-held theories on gamma-ray bursts (GRBs). The event, detected by NASA's Swift Observatory and Fermi Gamma-ray Space Telescope, reveals that kilonovae triggered by neutron star collisions can also produce long GRBs.

SourcePenn State·JournalNature·TypeObservational study·DateDec 7, 2022

Why synonymous mutations are not always silent

Researchers modeled how genetic changes affecting protein synthesis speed can lead to misfolding and altered activity levels in proteins. This finding suggests the importance of kinetics alongside sequence for determining protein structure and function, with potential implications for fields such as biopharmaceutics and medicine.

SourcePenn State·JournalNature Chemistry·TypeComputational simulation/modeling·DateDec 5, 2022

Why synonymous mutations are not always silent

Researchers found that synonymous mutations can lead to misfolding and reduced protein activity due to kinetic partitioning. The study suggests a new mechanism of action for these genetic changes, which could have implications in fields like biopharmaceutics.

SourcePenn State·JournalNature Chemistry·TypeExperimental study·DateDec 5, 2022

New clues about how carbon dioxide affects bumble bee reproduction

A recent study found that carbon dioxide changes the way macronutrients are stored and reallocated in the body of bumblebee queens. The researchers discovered that carbon dioxide induces a change in metabolism, which then triggers secondary effects on reproduction, contrary to previous hypotheses.

SourcePenn State·JournalInsect Biochemistry and Molecular Biology·DateNov 30, 2022

What shapes the composition of microbes in a warbler’s gut?

A team of researchers from Penn State found that the microbiomes of warblers are influenced more by evolution than diet, contrary to a recently proposed hypothesis. The study's results suggest that evolutionary history plays a larger role in determining the diversity of bacteria within birds' gut microbiomes.

SourcePenn State·JournalMolecular Ecology·DateNov 21, 2022

Word choice and media exposure affected anti-Asian boycotts during the pandemic

A new study by Penn State researchers found that using China-specific language in discussions of the pandemic contributed to anti-Asian boycotts. People with high media exposure displayed high levels of anxiety, while moderate exposure led to increased anxiety when reminded of the virus's deadly nature and its connection to China.

SourcePenn State·JournalInternational Journal of Hospitality Management·DateNov 15, 2022

New statistical method improves genomic analyzes

A new statistical method called CLIMB provides a more efficient way to analyze genomic data across multiple conditions. The method combines principles from two traditional techniques, reducing computational intensity and producing biologically interpretable results.

SourcePenn State·JournalNature Communications·TypeData/statistical analysis·DateNov 14, 2022

New hybrid structures could pave the way to more stable quantum computers

Researchers at Penn State have created a two-dimensional heterostructure by combining a topological insulator with a monolayer superconductor, demonstrating topological superconductivity and Ising-type superconductivity. The hybrid structure could pave the way for more stable quantum computers and explore Majorana fermions.

SourcePenn State·JournalNature Materials·TypeExperimental study·DateOct 27, 2022

Traces of ancient ocean discovered on Mars

Researchers have found conclusive evidence of a 3.5-billion-year-old shoreline with substantial sedimentary accumulation on Mars' northern hemisphere. The discovery provides key insights into the planet's ancient climate and its evolution, as well as the potential for life.

SourcePenn State·JournalJournal of Geophysical Research Planets·TypeData/statistical analysis·DateOct 27, 2022

Cancer drug could potentially be used against malaria

Researchers found that sapanisertib can kill the malaria parasite at several stages during its life cycle, including in the liver and red blood cells. The study's findings offer new hope against a disease that kills over half a million people annually.

SourcePenn State·JournalScience Translational Medicine·TypeExperimental study·DateOct 26, 2022

Researchers 3D bioprint breast cancer tumors, treat them in groundbreaking study

A team of researchers has successfully 3D bioprinted breast cancer tumors, treated them with chemotherapy and CAR-T cells, and found promising results. The bioprinted tumor model enabled the testing of experimental therapies without animal experimentation, laying the foundation for precision fabrication of tumor models.

SourcePenn State·JournalAdvanced Functional Materials·TypeExperimental study·DateOct 18, 2022

Eating fire ants could prepare lizards for future fire ant attack

A new study by Penn State researchers found that eating fire ants enhances a lizard's immune system, increasing its ability to survive a fire ant attack. The study revealed three immune measures were boosted in lizards fed fire ants, which could help them prepare for future venom exposure.

SourcePenn State·JournalBiological Invasions·TypeObservational study·DateOct 17, 2022

Myocarditis seven times more likely with COVID-19 than vaccines

A recent study by Penn State College of Medicine scientists found that the risk of developing myocarditis — inflammation of the heart muscle — is seven times higher with COVID-19 infection than with COVID-19 vaccination. Patients with myocarditis can experience chest pains, shortness of breath or an irregular heartbeat.

SourcePenn State·JournalFrontiers in Cardiovascular Medicine·DateOct 13, 2022

Medical history may help predict autism in young children, researchers find

A new study developed machine learning models to assess connections among hundreds of clinical variables and predict the likelihood of autism spectrum disorder in young children. The models used de-identified insurance claim data to identify risk factors and quantify their association with autism. This approach has promising potential ...

SourcePenn State·JournalBMJ Health & Care Informatics·TypeData/statistical analysis·DateOct 11, 2022