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Queen Mary University of London


First-of-its-kind test can predict dementia up to nine years before diagnosis

Researchers at Queen Mary University of London developed a predictive test using fMRI scans that detects changes in the brain's 'default mode network' to predict dementia. The test showed accurate predictions up to nine years before an official diagnosis, with greater than 80% accuracy and a two-year margin of error.

SourceQueen Mary University of London·JournalNature Mental Health·TypeObservational study·DateJun 6, 2024

Analysis of previously unstudied areas of the human genome suggests people with more copies of ribosomal DNA have higher risks of developing disease

A new study analyzed 500,000 individuals and found a strong statistical association between rDNA copy number and well-established markers of systemic inflammation, as well as kidney function. The research suggests that wider genome analysis could bring opportunities for preventative diagnostics and novel therapeutics.

SourceQueen Mary University of London·JournalCell Genomics·TypeData/statistical analysis·DateMay 14, 2024

New study uncovers why boys born to mothers with HIV are at greater risk of health problems and death in infancy

Researchers found that children born to mothers with HIV infection have an increased risk of immune abnormalities, impaired growth, and development. Infants exposed to HIV had a 41% higher mortality rate than those not exposed, with systemic inflammation being strongly associated with infant mortality.

SourceQueen Mary University of London·JournalNature Communications·TypeObservational study·DateApr 17, 2024

First new analysis in three decades identifies which treatments for the long-term effects of malnutrition could help reduce mortality and poor health outcomes for children

A new analysis has found evidence supporting the use of treatments to enhance mucosal healing and reduce inflammation in the gut, leading to improved outcomes for children with malnutrition. The study identified that a short course of treatment can restore mucosal integrity, reducing intestinal damage and systemic inflammation.

SourceQueen Mary University of London·JournalNature Communications·TypeRandomized controlled/clinical trial·DateApr 17, 2024

Inorganic nitrate can help protect patients against kidney damage caused during coronary angiographic procedures

A five-day course of inorganic nitrate significantly reduces contrast-induced nephropathy rates, improves three-month renal function, and lowers one-year major adverse cardiac events. The trial also shows improved kidney outcomes at three months compared to placebo.

SourceQueen Mary University of London·JournalEuropean Heart Journal·TypeRandomized controlled/clinical trial·DateMar 18, 2024

School-age girls with obesity are more likely to experience joint and muscle pain

Research by Queen Mary University of London found that girls with obesity are 1.7 times more likely than those with a healthy weight to have at least one GP consultation for musculoskeletal symptoms or diagnosis in childhood. Knee pain was the most common symptom reported, and researchers hope their findings will raise awareness about ...

SourceQueen Mary University of London·JournalArchives of Disease in Childhood·TypeData/statistical analysis·DateMar 12, 2024

Pore evolution secrets revealed: new study unlocks additive manufacturing potential

A new study has unlocked the secrets of pore evolution in directed energy deposition (DED) additive manufacturing, revealing five distinct processes that contribute to their behavior. The findings provide a detailed understanding of how pores form, move, and interact within the melt pool during DED, enabling targeted strategies to mini...

SourceQueen Mary University of London·JournalNature Communications·DateFeb 26, 2024

Terahertz biosensor detects skin cancer with remarkable accuracy, ushering in new era of early detection

A new terahertz biosensor has been developed to detect skin cancer with exceptional sensitivity, leveraging the unique properties of THz waves. The device analyzes a combination of parameters to provide a richer picture of tissue, allowing for accurate differentiation between healthy and cancerous cells.

SourceQueen Mary University of London·JournalIEEE Transactions on Biomedical Engineering·DateFeb 20, 2024

New treatment for a rare and aggressive cancer improves survival rates in breakthrough clinical trial

A new treatment combining a novel drug with traditional chemotherapy has been shown to increase the survival of patients with malignant mesothelioma, a rare and aggressive cancer. The ATOMIC-meso trial found that this treatment quadrupled the survival at 36 months compared to placebo-chemotherapy.

SourceQueen Mary University of London·JournalJAMA Oncology·TypeRandomized controlled/clinical trial·DateFeb 15, 2024

‘Rare positive result' in trial of new support intervention for people with dementia and their family carers

A new therapy called NIDUS-Family has shown promising results in improving the lives of people with dementia and their family carers. The study found that those who received the intervention were more likely to achieve their personal goals, such as increasing social engagement or improving caregiver support.

SourceQueen Mary University of London·JournalThe Lancet Healthy Longevity·TypeRandomized controlled/clinical trial·DateFeb 1, 2024

Hypertension's hidden hand: pressure-driven foam cell formation revealed as key driver of arterial disease, paving the way for new therapies

Researchers have discovered a novel mechanism by which elevated blood pressure transforms muscle cells into 'foam cells' that form the building blocks of plaque buildup in arteries. This finding provides crucial insights for developing new therapies to control or reverse arterial disease.

SourceQueen Mary University of London·JournalAdvanced Science·DateJan 5, 2024

Embargoed press release: Blood hormone levels key to identifying which post-menopausal women will benefit most from taking anastrozole to prevent breast cancer

A recent study published in Lancet Oncology has found that measuring blood hormone levels can identify post-menopausal women who are most likely to benefit from anastrozole, a medication used to prevent breast cancer. The study suggests that inexpensive blood tests could be used to personalize preventive therapy for these women.

SourceQueen Mary University of London·JournalThe Lancet Oncology·TypeRandomized controlled/clinical trial·DateDec 6, 2023

A participant from Queen Mary University of London Genes & Health study is the 10th person enrolled in a gene-editing clinical trial for heart disease

The Genes & Health study has enrolled its 10th participant in a gene-editing clinical trial for heart disease, specifically familial hypercholesterolemia. This milestone marks an important step towards improving health outcomes for people of Pakistani and Bangladeshi descent.

SourceQueen Mary University of London·TypeRandomized controlled/clinical trial·DateNov 12, 2023

Trust is the most important factor for British South Asians when taking part in genetic research to tailor medications

A study by Queen Mary University of London reveals that trust is the key factor in British South Asians' participation in genetic testing. Participants emphasize the importance of General Practitioners (GPs) as trustworthy professionals and personalized prescribing with genetic information to enhance trust and medication adherence.

SourceQueen Mary University of London·JournalThe Pharmacogenomics Journal·TypeObservational study·DateOct 31, 2023

Research group wins ERC Synergy grant for development of revolutionary colorectal cancer screening and treatment system

A research group led by Professor Kaspar Althoefer has been awarded a €10m ERC Synergy grant to develop a revolutionary new system for screening and treating colorectal cancer. The system, which combines medical robotics, artificial intelligence, and minimally invasive surgery, aims to improve patient outcomes and quality of life.

Tropical ecosystems more reliant on emerging aquatic insects, study finds, potentially putting them at greater risk

Researchers found tropical forest ecosystems rely more on aquatic insects than temperate forests, making them vulnerable to disruptions in land-water connections. This increased reliance poses a threat to tropical environments, which are already under pressure from human activity and climate change.

SourceQueen Mary University of London·JournalEcology Letters·TypeExperimental study·DateOct 9, 2023

One-hour training is all you need to control a third robotic arm

Researchers at Queen Mary University of London and their colleagues have found that supernumerary robotic arms can be used as effectively as a partner, enabling tasks like opening doors while carrying packages. The study suggests these arms could aid people with various tasks, such as surgery or industrial work.

SourceQueen Mary University of London·JournalIEEE Open Journal of Engineering in Medicine and Biology·DateSep 26, 2023

E-cigarettes are not a gateway into smoking

A comprehensive study found no evidence that e-cigarettes promote smoking and may even compete against cigarettes, potentially speeding up the decline in smoking rates. The study compared countries with different e-cigarette regulations and found a slower decline in smokers among those with stricter controls.

SourceQueen Mary University of London·JournalPublic Health Research·DateSep 21, 2023

Freshwater connectivity can transport environmental DNA through the landscape

Research finds that water movement between lakes can transport environmental DNA, making eDNA a promising tool for tracking aquatic species and monitoring biodiversity. The study highlights the importance of considering landscape connectivity when designing eDNA surveys to ensure accurate biodiversity assessments.

SourceQueen Mary University of London·JournalProceedings of the Royal Society B Biological Sciences·DateSep 12, 2023

New study finds ways to suppress lithium plating in automotive batteries for faster charging electric vehicles

A new study led by Dr. Xuekun Lu has found a way to prevent lithium plating in electric vehicle batteries, which could lead to faster charging times and improve the battery's energy density. The research also reveals that refining the microstructure of the graphite electrode can minimize the risk of lithium plating.

SourceQueen Mary University of London·JournalNature Communications·DateAug 24, 2023