The NHS Breast Screening Programme is associated with modest overdiagnosis of breast cancer, estimated at 3.7% of screen detected cancers. However, the benefits of screening in preventing deaths from breast cancer outweigh this risk, according to a recent study.
A recent study found that half of patients in East London regularly see the same GP, a crucial factor in better patient outcomes. The researchers highlight the need for policymakers to measure and incentivize continuity of care to improve health outcomes.
A study by Queen Mary University of London found that 26% of patients with asthma are overusing rescue inhalers, which can lead to poor asthma control and increased risk of severe attacks. By reducing SABA overprescribing, hospitals can see a 70% decrease in asthma-related hospital admissions.
Researchers at Queen Mary University of London have identified genes that can predict response to arthritis treatment and paves the way for future drug development. The study found specific gene signatures associated with resistance to current therapies, which could lead to new treatments.
A new study from Queen Mary University of London suggests that e-cigarettes are just as safe as nicotine patches for pregnant smokers and may help more women quit smoking. The study found that e-cigarette users had better proven quit rates at the end of pregnancy compared to those using nicotine patches.
Researchers analyzed 110 studies and found that unvaccinated individuals with pre-existing heart conditions are up to nine times more likely to suffer severe outcomes, including death. The study identified multiple predictors of worse Covid-19 outcomes in unvaccinated patients compared to vaccinated individuals.
Research published in Science Advances discovers the importance of pressure sensing combined with stiffness sensing in determining vascular smooth muscle cell behavior. The study identifies molecular pathways related to mechanical sensing in cells and tissues, shedding light on potential new strategies for targeting atherosclerosis.
Researchers at Queen Mary University of London identified a way to overcome resistance to cancer drugs in leukemia cells by manipulating cellular pathways. By using a sequential treatment approach, the team was able to kill about 50% of leukemia samples and potentially develop a new treatment strategy for this devastating disease.
Researchers found a new form of ant society that emerged in one species and then spread to other species through hybridization. This allowed the ants to outcompete single-queen colonies and become more successful.
A pioneering UK study has found that hearing loss and epilepsy are early features of Parkinson's disease, appearing up to ten and five years before diagnosis respectively. The research, conducted on a diverse population in East London, also uncovered novel risk factors for the condition.
A genetic study published at Queen Mary University of London found that individuals with higher genetic sensitivity benefit more from couple's therapy, particularly in the long-term. The researchers used genome-wide data to assess genetic sensitivity and found that it had a significant impact on marital satisfaction over time.
A new study from Queen Mary University of London demonstrates the effectiveness of a compact Covid-19 testing kit, which uses low-cost hardware and is relatively inexpensive to make. The kit offers a promising solution for remote areas with limited access to well-equipped testing labs or trained personnel.
A new study provides a detailed timeline of mammal evolution, confirming that modern placental mammal groups postdate the K-Pg extinction. The researchers used a novel computational approach to analyse a large genomic dataset and answer a long-standing question about mammal origins.
A recent study published by Queen Mary University of London has found that certain risk factors for heart disease are linked to changes in the structure and appearance of the heart. The research analyzed images from over 30,000 people's heart MRI scans using a new imaging toolkit called radiomics.
Researchers developed a new process to produce stable formamidinium perovskite (FAPbI3) materials, which can be used to make more efficient and stable solar cells. The novel approach uses lower temperatures and eliminates additives, making it suitable for large-scale production and flexible solar cell applications.
Research from Queen Mary University of London and Cardiff University found that certain MS treatments can reduce Covid-19 vaccine effectiveness in people with MS. The largest peer-reviewed study on the topic provides high-quality evidence to inform clinicians' guidance on treatment options.
A new treatment target for lymphoma has been identified as protein KDM5, which may reverse the effects of KMT2D mutations in cancer cells. The international collaboration aims to identify patient groups most likely to benefit from this type of treatment and explore its therapeutic potential across various lymphoma subtypes.
Researchers have discovered a specific type of gut bacteria in bees that can improve memory, with bumblebees showing enhanced memory when fed this bacteria. The study suggests a causal link between the gut microbiome and cognitive abilities, opening up possibilities for similar effects in humans.
A clinical trial found that long-term weight loss was similar for those who received 5:2 diet or standard weight management advice, with 18% and 15% of participants losing at least five per cent of their body weight. However, the 5:2 diet group was more likely to recommend the intervention to others or continue with it.
A world-first study published in the New England Journal of Medicine found that whole genome sequencing can uncover new diagnoses for people with rare diseases. The pilot study analyzed 4,660 individuals and found a new diagnosis for 25% of participants, including 14% not detectable by other conventional methods.
Researchers at Queen Mary University of London have discovered a new way to analyze diseased and healthy cells from the same patient, revealing potential targets for individualized treatments. The study's findings could also help predict patient response to current drugs, leading to improved survival rates.
Researchers at Queen Mary University of London have created an experimental model of cardiomyopathy in inflammatory arthritis, replicating symptoms in RA patients. The study identifies a potential therapeutic approach to treat cardiomyopathy in RA patients.
A recent study found that individuals with COVID-19 are at a higher risk of developing phlebitis and thrombophlebitis, as well as blood clots in the leg and lung. The study also identified associations between general COVID-19 susceptibility and increased blood clot events and circulatory diseases.
Researchers found that injecting SK/CCK-type neuropeptides into starfish retracts their stomachs and makes them less inclined to eat, even with food in front of them. This discovery sheds light on the evolutionary conservation of feeding regulation mechanisms across animals.
Patients from minority ethnic groups have a disproportionately higher rate of emergency hospital admissions due to comorbidity profiles and earlier onset burdens of diseases. The study found that these disparities are not reflected in commonly used measures like survival rates.
Researchers discovered that fetal membranes can heal after injury through the action of cells called myofibroblasts and protein Cx43. This finding holds promise for reducing the risk of birth complications from preterm prelabour rupture of the membranes, a leading cause of early infant death.
A unique pair of gene variants has been found to cause sudden onset high blood pressure in pregnant women, which can be treated with a procedure to remove the adrenal nodule. The discovery provides new hope for women affected by this condition.
Researchers at Queen Mary University of London confirmed HER2's role in predicting DCIS recurrence and response to adjuvant radiotherapy. HER2 overexpression is associated with a significantly increased risk of in situ recurrence.
A recent study by Queen Mary University of London provides new insight into the mechanisms behind uncontrolled inflammation in COVID-19 patients. The research found that treatments increasing specialised pro-resolving mediators (SPM) production, such as dexamethasone, may play a key role in limiting disease severity.
Researchers discovered how protective molecules like SPM are altered in COVID-19 patients, suggesting that increasing these molecules could limit inflammation and disease severity. The study also found that dexamethasone increased SPM production, improving white blood cell function and reducing inflammation.
Researchers have created artificial swimmers that use fluctuating temperature changes to store energy and swim independently. These microswimmers can harness heat from their environment to recharge multiple times, opening up possibilities for studying biological interactions.
A study by Queen Mary University of London and University of Oxford found that lateral flow tests are 95% effective in detecting Covid-19 when used at the onset of symptoms. The findings support using lateral flow tests as an alternative to PCR testing among symptomatic patients.
Researchers at Queen Mary University of London have discovered that immune cells can be stimulated to assemble into special structures within pancreatic cancer, improving the efficacy of chemotherapy. The findings suggest a potential therapeutic strategy for promoting an anti-tumour immune response in patients.
A new AI tool automatically measures fat around the heart from MRI scan images, linking it to increased diabetes risk. The tool was tested on over 45,000 people and accurately calculated their risk of developing diabetes.
A new study has identified a protein called pentraxin 3 (PTX3) that may be used to aid in the diagnosis of pancreatic cancer. PTX3 levels were found to be significantly higher in patients with pancreatic ductal adenocarcinoma, a type of pancreatic cancer.
A clinical trial by Queen Mary University of London found that e-cigarettes are more effective than nicotine replacement treatments in achieving long-term smoking reduction and cessation. After six months, 27% of participants who used e-cigarettes had reduced their smoking by at least half, compared to 6% of those who used NRTs.
A blood test detecting tiny amounts of circulating cancer DNA may identify risk of cancer recurrence and guide precision treatment in bladder cancer following surgery. The study found patients with a particular cancer DNA marker in their blood had a higher likelihood of cancer relapse, suggesting the potential for personalized treatment.
A global multicentre clinical trial found that a one-hour ultrasound-based procedure called 'renal denervation' significantly reduced blood pressure in resistant hypertension patients. The study, published in The Lancet, suggests this procedure could offer hope to patients who do not respond to recommended treatments.
Researchers at Queen Mary University of London tested an algorithm on 700,000 patient records in east London to identify Familial Hypercholesterolemia, a leading cause of heart attacks in young people. The 'FAMCAT' algorithm analyzes GP data and family history to predict who may be at risk.
A new study highlights the surprising similarities between quark-gluon plasma, the first matter thought to have filled the early Universe, and ordinary liquids. The ratio of viscosity and density is crucial in determining fluid flow, and researchers found that this ratio is the same for both quark-gluon plasma and water.
Scientists tracked individual honeybee drones using radar technology, revealing their mating behaviors and finding that they move between multiple congregation areas during a single flight. This discovery suggests the existence of a new type of animal mating system in honeybees.
A study by Queen Mary University of London compared the safety and effects of heat not burn product IQOS with cigarettes, Juul, and refillable e-cigarettes. IQOS delivered less nicotine, had lower nicotine delivery than Juul, and was less effective in reducing urges to smoke.
Research at Queen Mary University of London found that individuals with healthier hearts perform better in logic-based problems and have faster reaction times. Shared risk factors, such as diabetes and obesity, may also play a role in mediating interactions between heart and brain health.
Researchers have discovered a new compound, inositol hexaphosphate, that can inhibit the growth of medulloblastoma, a common high-grade brain tumour in children. The finding could lead to improved treatments for this devastating disease, with potential benefits for patients whose tumours are resistant to chemotherapy.
Research from Queen Mary University of London reveals that chemotherapy activates immune cells within the tumor microenvironment to fight against cancer. Macrophages switched from pro-tumour to anti-tumour mode after chemotherapy, stimulating patient's immune response and potentially improving survival outcomes.
A proof-of-concept study shows that animal DNA can be collected from air samples, enabling new ecological and health assessments. The technique has potential applications in forensics, anthropology, and even medicine, such as understanding airborne diseases like Covid-19.
Researchers from Queen Mary University of London developed a machine learning algorithm that ranks cancer drugs based on their effectiveness in reducing cancer cell growth. The approach has the potential to advance personalized therapies by allowing oncologists to select the best drugs for individual patients.
A large proportion of dementia deaths in England and Wales may be due to socioeconomic deprivation, according to new research. The team found that socioeconomic deprivation was associated with younger age at death and poorer access to accurate diagnosis.
Researchers from Queen Mary University of London confirmed the role of oestrogen receptor biomarker in ductal carcinoma in situ and developed a new, more accurate method to predict long-term outcomes. The study found ER expression is a strong prognostic factor for recurrence in DCIS.
A study by Queen Mary University of London found that combining subsidies with behavioral interventions led to a 24% reduction in weekly carbon emissions. Subsidizing low-carbon emission meals was more effective than using carbon taxes or traffic light labelling alone.