A study by UC Davis researchers found biological indicators of toxic fat cells in those with metabolic syndrome, which may lead to diabetes and cardiovascular disease. The discovery supports a new high-risk obesity category for these conditions.
The number of hospitalizations for skin and soft-tissue infections, primarily caused by community-acquired Methicillin-resistant Staphylococcus aureus (MRSA), has more than doubled since 2000. Early treatment and recognition are crucial to preventing hospitalization.
A large international multi-site study found the recurrence risk of autism in younger siblings to be substantially higher, with a combined estimated risk of nearly 19%. The risk is especially elevated among male infants, with over 32% diagnosed with an autism spectrum disorder
UC Davis investigator provides roadmap to overcome obstacles for using induced pluripotent stem cells to treat various human diseases. The technology has the potential to bypass immunological problems inherent in traditional stem cell therapy.
Most victims of stray bullets are women and individuals outside the typical high-risk age range, highlighting the need for preventive measures. The study found that most victims were unaware of the events leading to the gunfire and often died immediately or shortly after being shot.
A large UC Davis study analyzed 1.6 million mammograms and found that computer-aided detection (CAD) technology is not effective in finding breast tumors, leading to increased false-positive results and unnecessary recalls for further testing.
A recent study published in International Journal of Cancer found that boosting the production of a specific microRNA, miR-34a, increases sensitivity of bladder cancer cells to chemotherapy. The study suggests that miR-34a may be used as a predictor of response to chemotherapy and a target for new drugs.
A large national multi-center study found that most children with minor blunt head trauma and normal CT scans do not require hospitalization for further observation. Children who were hospitalized after normal CT scans did not have subsequent abnormal CT scans or MRIs, and none required neurosurgical intervention.
A new sealant gel has been found to be effective in closing spinal wounds following surgery, achieving a watertight seal 100% of the time. The polyethylene glycol (PEG) hydrogel sealant plugs miniscule leaks in the spinal column's sheath, reducing the risk of infection and meningitis.
Women who took daily prenatal vitamins before and during pregnancy were less likely to have children with autism, especially those with high-risk genetic makeups. Folate and B vitamins in prenatal supplements may protect against early fetal brain development deficits.
A study of over 6.6 million California births from 1990 to 2002 found that children conceived in winter had a significantly greater risk of autism. The risk increased progressively throughout the fall and winter months, with the highest risk seen in March.
Mexican migrants to the U.S. are at a higher risk of experiencing clinically significant depression and anxiety disorders compared to non-migrants. The study found that those between 18 and 25 years old have nearly four-and-one-half times greater odds of developing a depressive disorder.
A study by UC Davis researchers found that frequent CT scans for testicular cancer surveillance are associated with a higher risk of secondary malignancies in older men. The study suggests that alternative imaging techniques, such as ultrasound and MRI, may be more suitable.
Researchers at UC Davis have discovered a link between two major biological pathways involved in pain, which may pave the way for new treatments. The study found that inhibitors of the enzyme sEH can alleviate debilitating pain by targeting the messenger cAMP.
Researchers at UC Davis School of Medicine found that children exposed to coal emissions for heating and cooking had shorter stature at 36 months compared to those in households using other fuels. The study notes that the difference is not large but indicates a possible influence on growth processes.
A UC Davis study found that detection dog teams were more likely to alert to scents in rooms indicated by human cues, such as construction paper. The researchers suggest that subtle handler cues may be influencing the dogs' behavior, similar to the 'Clever Hans' effect seen in horses.
New research from UC Davis Cancer Center found that colon cancer screening rates vary significantly across geographic regions, with African Americans and Hispanics facing lower rates. In contrast, Asian-Pacific Islanders in Hawaii had the highest screening rates among any group, suggesting potential cultural factors at play.
A new study by UC Davis researchers found that Southeast-Asian-American families with children having developmental disabilities face significant obstacles in receiving intervention services. Barriers include limited information, language difficulties and a perception that reliance on government support is not acceptable.
Researchers at UC Davis Health System found significantly reduced vitamin D levels in patients with metabolic syndrome living in Northern California. The study suggests that supplementation with vitamin D may reduce the risk of diabetes and heart disease, contradicting previous assumptions about adequate sun exposure in sunny latitudes.
A new study by UC Davis researchers found that children with autism have deficits in cellular energy production, suggesting a strong link between autism and mitochondrial defects. The study's lead author suggests that deficiencies in mitochondria may contribute to cognitive impairments associated with autism.
A new study found that patients with head and neck cancer who have never smoked have significantly better survival rates and fewer treatment complications than smokers. The researchers suspect that human papillomavirus may play a role in this difference.
A new study by UC Davis researchers reveals that silent vascular disease is common among healthy, active older adults and can lead to subtle deficits in mental functioning. The study found that white matter hyperintensities are associated with greater declines in global cognition over time.
A study found that an annual conventional Pap smear is a cost-effective strategy for follow-up after cervical lesion treatment. This approach reduced expected cervical cancer deaths by 73-77% compared to more frequent testing.
A phase II clinical trial found tanezumab to be effective in reducing osteoarthritis knee pain, with a 62% reduction in walking knee pain compared to placebo. The drug also showed promise in improving physical function and relieving stiffness.
Researchers at UC Davis discovered that Salmonella bacteria create an environment in the human intestine to enhance its reproductive success. The bacteria use tetrathionate respiration, a sulfur compound produced by the immune system's response, to outgrow beneficial microbes and promote severe diarrhea.
A team of UC Davis scientists discovered a novel mechanism behind Vioxx's link to heart attacks and strokes, finding that the drug increases a regulatory lipid that contributes to cardiovascular events. The research may pave the way for safer coxibs for millions of arthritis patients.
A new survey study found that parents of children with fragile X syndrome reported improvements in language use, attention spans, and behavior after treatment with the antibiotic minocycline. The study suggests that minocycline may be a promising targeted treatment for fragile X, prompting further clinical trials.
Scientists have identified a new area of the brain that generates excitatory neurons in adults, which arise from non-neuronal support cells. This finding has significant implications for regenerative medicine and may lead to new treatments for brain injuries or disorders.
The study found significant disparities in survival rates among Asian-Americans diagnosed with liver cancer, with Laotian/Hmong-Americans having the lowest median survival rate of just one month. The group was also least likely to receive treatment, such as liver transplantation, due to late-stage diagnoses.
A pilot study led by UC Davis School of Medicine found that specifically asking young women about pregnancy coercion during reproductive health visits can reduce the likelihood of future pressure, with a 70% drop in odds. The intervention also increased awareness of intimate-partner violence resources.
Researchers have purified the protein produced by the breast cancer susceptibility gene BRCA2, opening new possibilities for understanding, diagnosing, and treating breast cancer. The protein plays a role in repairing damaged DNA, acting as a mediator to help another protein associate with a single strand of DNA.
Scientists use cutting-edge microscope to measure how brain cells respond to pressure, finding that intermediate form of amyloid-beta peptide stiffens cells the most. This discovery could lead to new ways to screen drugs for Alzheimer's and similar diseases.
A new study from UC Davis found that changing training techniques can reduce shear forces on knee joints, which may help prevent ACL injuries. The research involved female basketball players who learned to land on their toes and balls of the feet, resulting in a 56% reduction in tibial shear force.
A study by UC Davis researchers has demonstrated the effectiveness of asynchronous telepsychiatry in assessing patients' mental health, using store-and-forward technology. The approach allows psychiatrists to provide opinions to primary-care doctors quickly and efficiently, with high accuracy and feasibility.
Scientists have discovered that neuroglobin protects cells from stroke damage, amyloid toxicity, and lack of oxygen. High levels of neuroglobin in brain neurons may buffer them against the effects of Alzheimer's disease-causing protein accumulation.
Researchers found that people with better mental health felt less pain, while those with worse mental health experienced more. The study suggests that mental-health treatment could be an effective way to lessen arthritis pain.
A study by researchers at UC Davis found that students with ADHD are less likely to finish high school on time than those with other mental-health disorders. Smoking is the strongest predictor of high school dropout among teens who engage in substance use.
A new research paper proposes a six-step decision-making approach to facilitate shared decision-making between parents and physicians for infants born with genetic or anatomical anomalies in sexual development. The process aims to clarify reasons, identify gaps in understanding, and explore values underlying decisions. By working on th...
A novel microfluidic HIV test developed by Prof. Alexander Revzin uses antibodies to 'capture' white blood cells called T cells affected by HIV. The test detects the types and levels of inflammatory proteins released by the cells, providing six parameters simultaneously from a small blood sample.
Researchers at UC Davis have found a distinctive pattern of brain imaging and biomarker deviations that may indicate an early warning sign of Alzheimer's disease. The study, published in Neurobiology of Aging, analyzed data from over 800 older adults and identified three subgroups with distinct imaging and laboratory measures.
A study by UC Davis researcher Joshua Fenton found that use of computer-aided detection (CAD) in mammography screenings surged after Medicare began covering its cost. The prevalence of CAD increased from 5% to 27% between 2001 and 2003, despite uncertainty over its clinical impact on breast cancer outcomes.
A UC Davis study found that online games and websites marketed to children are predominantly branding tools, with nutrition information often buried or absent. The researchers recommend increased regulation to prevent childhood obesity and promote healthier eating habits.
Researchers from UC Davis Health have found E. coli O157:H7 in fecal samples of wildlife species common to California's Central Coast region, including cowbirds, coyotes, crows, mice, and feral pigs. While the presence of the bacterium is rare, it suggests there are potential sources of pathogen movement that need to be assessed.
A study by UC Davis researchers has identified a blood component, lipoprotein-associated phospholipase A2 (Lp-PLA2), as a predictor of coronary artery disease in African-Americans. The finding highlights the role of inflammation in vascular disease among this ethnic group and may lead to more targeted treatment approaches.
A new UC Davis study found that low-wage workers are more likely to be obese due to limited access to healthier food and physical activity options. Raising minimum wages may help expand access to healthier lifestyle choices.
A study by UC Davis researchers found that endovascular stent implantation outperforms traditional open-chest surgery in treating thoracic aortic tears. Patients who received stents experienced less kidney failure, lower death rates, and shorter recovery times.
Researchers at UC Davis Cancer Center found that African-American women with advanced breast cancer have poorer survival rates than white and Hispanic counterparts, regardless of radiation therapy. Despite lower radiation therapy rates, black patients did not benefit from the treatment.
A study by UC Davis researchers found that consuming walnuts can significantly slow prostate cancer growth in mice. The walnut diet resulted in smaller tumors and reduced levels of the protein IGF-1, which is associated with prostate cancer.
Researchers at UC Davis have found a strong association between cognitive deficits and decreased levels of the neurotransmitter gamma-aminobutyric acid (GABA) in patients with schizophrenia. The study suggests that targeting the GABA system may help address cognitive decline in the disorder.
A national study suggests that pediatric residents and all physicians need individualized learning plans to keep pace with emerging health-care advances. The study found that tracking progress toward achieving learning goals is crucial, and faculty mentors can help residents develop effective plans.