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University of California - Los Angeles Health Sciences


UCLA study finds heart failure medications highly cost-effective

A UCLA study found that heart failure medications recommended by national guidelines are highly cost-effective in saving lives and may also provide savings to the healthcare system. The combination of these medical therapies demonstrated the greatest gains in quality-adjusted life years for heart failure patients.

SourceUniversity of California - Los Angeles Health Sciences·JournalJournal of the American College of Cardiology·DateMar 28, 2013

Outside the box: UCLA uses brain aneurysm treatment to stop irregular heart rhythms

Researchers at UCLA successfully treated two patients with severe ventricular arrhythmias using a minimally invasive technique normally employed in treating brain aneurysms. The coil embolization procedure helped stop the electrical storms and eliminate the blood supply to the affected area, allowing the heart to return to normal rhythm.

Wolf in sheep's clothing: Uncovering how deadly bacteria trick the immune system

A recent UCLA study reveals that certain bacteria, including those causing tuberculosis, can pretend to be viruses when infecting humans. This allows them to hijack the immune response and hide out inside cells. The findings may also explain how viral infections like the flu make us more susceptible to bacterial infections like pneumonia.

UCLA study finds endocrine disorder is most common cause of elevated calcium levels

A new UCLA study reveals that primary hyperparathyroidism is the leading cause of high blood-calcium levels, affecting mainly women and the elderly, particularly African American women over 50. The condition can lead to bone loss, depression, fatigue, and increased risk of osteoporosis and fractures.

SourceUniversity of California - Los Angeles Health Sciences·JournalThe Journal of Clinical Endocrinology & Metabolism·DateFeb 21, 2013

Social media may prove useful in prevention of HIV, STDs, study shows

Researchers found that African American and Latino men who have sex with men voluntarily used health-related Facebook groups to discuss HIV knowledge, stigma, and prevention, leading to increased requests for home-based HIV tests. The study suggests social media can be a useful tool for collecting and analyzing data, saving money and i...

SourceUniversity of California - Los Angeles Health Sciences·JournalSexually Transmitted Diseases·DateFeb 6, 2013

UCLA study first to image concussion-related abnormal brain proteins in retired NFL players

Researchers have developed a new technique to identify abnormal tau proteins associated with repetitive head injuries, potentially leading to earlier diagnosis and tracking of brain disorders. The study used PET scans to detect elevated levels of FDDNP in the brains of five retired NFL players.

SourceUniversity of California - Los Angeles Health Sciences·JournalAmerican Journal of Geriatric Psychiatry·DateJan 22, 2013

Childhood obesity linked to more immediate health problems than previously thought

A new UCLA study reveals that obese youngsters are at far greater risk of having three or more reported medical, mental, or developmental conditions compared to their non-overweight peers. The researchers found a nearly twice the risk of obesity, as well as a higher likelihood of poorer health, disability, and emotional problems.

Simple intervention helps doctors communicate better when prescribing medications

A new study led by UCLA researcher Dr. Derjung Tarn found that a simple training program improved physicians' ability to communicate key facts about prescribed medications, including potential side effects and medication adherence. The intervention resulted in higher ratings from patients on communication about medications.

SourceUniversity of California - Los Angeles Health Sciences·JournalThe Annals of Family Medicine·DateJan 14, 2013

Genes and obesity: Fast food isn't only culprit in expanding waistlines -- DNA is also to blame

A new study reveals that genetic factors significantly contribute to obesity, with DNA influencing body-fat responses to high-fat, high-sugar diets. The research found that genetics account for up to 80% of the variation in body-fat percentage among mice, suggesting a strong link between DNA and fat gain.

Taking race out of the equation in measuring women's risk of osteoporosis and fractures

A new approach for assessing fracture risk combines bone density measures with body size and bone size, predicting risk accurately regardless of race or ethnicity. The study found that this composite bone strength index performed just as well as traditional methods in a group of nearly 2,000 women.

SourceUniversity of California - Los Angeles Health Sciences·JournalThe Journal of Clinical Endocrinology & Metabolism·DateOct 18, 2012

UCLA scientists fine-tune probe for early Alzheimer's detection

Researchers have discovered how chemical agents bind to and detect amyloid beta plaques and tau tangles in the brain, enabling quicker diagnosis and earlier treatment. The study's findings will speed the development of new imaging agents, providing potential benefits for patients with early Alzheimer's disease.

SourceUniversity of California - Los Angeles Health Sciences·JournalProceedings of the National Academy of Sciences·DateSep 24, 2012

UCLA stem cell researchers use gene therapy to restore immune systems in 'bubble babies'

Researchers at UCLA have developed a gene therapy regimen that safely restores immune systems to children with ADA-deficient severe combined immunodeficiency (SCID), a devastating disease. The treatment showed promising results in restoring immune function to three out of six patients, offering new hope for these children.

More sophisticated wiring, not just bigger brain, helped humans evolve beyond chimps

A new UCLA study identifies uniquely human patterns of gene activity in the brain that could deepen our understanding of human evolution and brain diseases. The research suggests that complex signaling pathways and enhanced cellular function in the frontal lobe created a bridge to human evolution, enabling higher rates of learning.