A new UCLA study found that sepsis accounts for a significant percentage of hospital readmissions in California, with an estimated annual cost of $500 million. The study also revealed disparities in readmission rates among different demographics, highlighting the need for targeted interventions to address this critical issue.
A UCLA review of common practices in prostate cancer has found that monitoring men with very low- and low-risk prostate cancers using watchful waiting or active surveillance is an effective approach for many patients. This approach could spare them the debilitating side effects of aggressive treatments, which are often used unnecessari...
Researchers identified individual neurons in the medial temporal lobe that changed their firing to encode new associations at the exact moment of the experience. This finding may lead to a better understanding of memory loss and new methods to fight it in Alzheimer's and other neurological diseases.
New UCLA research reveals that vitamin B12 can lead to pimple-prone skin by changing the activity of facial bacteria. This finding may help identify new treatments for acne by targeting specific mechanisms in the skin. The study, published in Science Translational Medicine, sheds light on one key role that B12 plays in acne development.
Researchers used humanized mice to study the effects of cocaine on immune systems, finding that cocaine makes people more susceptible to HIV infection. The study suggests that cocaine blunts the body's defense against the virus and increases the pool of cells that can become infected.
A UCLA study finds that children with autism spectrum disorder who are overly sensitive to sensory stimuli have brains that react differently, leading to a condition called sensory over-responsivity. The research may lead to interventions that can help improve the lives of these children and their families.
Researchers at UCLA successfully tested a portable finger-probe device on 53 potential organ donors, predicting which livers would function properly after transplantation. The device could increase the number of organs used for transplant and save patients waiting for transplants from dying.
A new study finds that Twitter can provide valuable information about the health and social needs of transgender individuals, including mental health issues like depression. The researchers collected over 1,135 tweets containing relevant hashtags and analyzed the sentiments expressed in the tweets.
A recent UCLA study found that only 3.7% of US adults with pre-diabetes were prescribed metformin, despite its proven effectiveness. The study highlights the underuse of metformin for diabetes prevention, which could be attributed to lack of knowledge and reluctance by patients and doctors.
Parents of children with drug-resistant epilepsy describe their arduous journey to get referrals for surgery, highlighting delays and frustration. The study calls for interventions to target these barriers, aiming to improve access to specialty care.
A new study from UCLA has found that women experiencing extreme morning sickness during pregnancy are three times more likely to have children with attention disorders and language delays. In utero exposure to HG may be linked to nutrient deficiency and life-long effects on the exposed fetus.
A recent UCLA study found that only 9% of US academic medical practices have procedures for connecting patients to LGBT-competent physicians. This suggests a need for increased training and policies to support LGBT patient care. The study's findings highlight the importance of healthcare providers being aware of and sensitive to factor...
A UCLA study found that 77% of California physicians understand the basics of the Patient Protection and Affordable Care Act, with 59% supporting it. The survey also revealed a correlation between doctors' political affiliations and medical specialties.
A new imaging tool found a strikingly similar pattern of abnormal protein deposits in the brains of retired NFL players with concussions, which may help identify brain disorders like CTE. The study also shows differences in brain imaging patterns between concussed athletes and healthy individuals.
Researchers at UCLA find that HIV infection accelerates age-related epigenetic changes, leading to accelerated onset of diseases like cancer and osteoporosis. The study suggests that HIV itself may accelerate these aging-related changes by more than 14 years.
Researchers found that ECT alters the hippocampus and amygdala, structures linked to mood and learning, in patients with major depression. These changes correlated with improved mood and treatment response.
A new study published in the journal AIDS found that for most children with HIV and low immune cell counts, cells rebound after treatment. The researchers analyzed data from over 3,700 children infected with HIV before or during birth and found that 86% of children achieved normal CD4+ counts within one year of treatment.
A new on-board air filtration system developed for school buses reduces exposure to vehicular pollutants by up to 88%, making it cleaner way to transport children. The HECA filtration system could protect the 25 million American children who commute on school buses nearly every day from harmful exposures.
The rate of Latino physicians per 100,000 Latinos in the US has declined by 22% since 1980, according to a new study. The shortage of culturally familiar doctors negatively affects healthcare for U.S. Latinos, who face barriers to quality care due to language and cultural barriers.
A new method has been developed to deliver promising treatments to stroke patients quickly, thanks to the work of paramedics. By working with paramedics in the field, intravenous medications can be given to patients within the 'golden hour,' the window in which brain damage is minimized.
A UCLA study reveals that parents' long-term goals for their children play a significant role in predicting math and reading abilities. Children from poorer families tend to perform worse despite similar family incomes, due to factors like younger mothers, reduced parental interaction, and limited access to educational resources.
Researchers at UCLA have found that a deficiency of the hormone hepcidin makes people with iron overload disease susceptible to Vibrio vulnificus infections. A medical form of hepcidin, minihepcidin, has been shown to cure the infection by restricting bacterial growth.
A novel nomogram was developed by UCLA researchers to accurately calculate the risk of disease recurrence in liver cancer patients after a liver transplant. The tool uses pre-transplant radiologic information, blood biomarkers, and pathological characteristics to predict recurrence rates.
Researchers at UCLA have discovered a genetic link between PTSD and two gene variants, COMT and TPH-2. These variants may contribute to the onset and persistence of the disorder, suggesting that heredity influences a person's risk of developing PTSD. The findings could lead to faster diagnosis and better treatment for survivors.
A UCLA study found that early exposure to antidepressants can impact adult anxiety behavior, with Lexapro potentially altering serotonin neurotransmission and reducing anxiety in mice. The research highlights the need for safer antidepressant options during pregnancy.
A new study from UCLA found that combining social media with behavioral psychology increased HIV testing rates among men who have sex with men in Peru. The Harnessing Online Peer Education intervention was more effective than traditional care through social media, suggesting a valuable tool in the fight against HIV.
Researchers found that higher-earning clinicians earn more by providing more services per patient, rather than seeing more patients. This challenges the current fee-for-service payment model, which may not incentivize clinicians to prioritize quality of care.
A randomized clinical trial found that perineal self-acupressure helped participants break up hard stools, relax muscles, and stimulate nerves responsible for bowel movements. 72% of patients reported improvement in their constipation symptoms after performing the technique for four weeks.
Researchers discovered that statins can reverse the learning deficits caused by Noonan syndrome, a genetic disorder affecting 1 in 2,000 people. The treatment works by reducing Ras activity, allowing brain cells to communicate properly and enabling normal learning to take place.
Asthma is a widespread disease that causes genetic damage in peripheral blood, leading to oxidative stress and DNA damage. The study found four types of systemic effects, including protein damage, which can result in unstable chromosomes and increase the risk of other diseases.
A UCLA study found that patients with bladder cancer who did not receive optimal biopsies had a significantly higher risk of death from the disease. In fact, about half of patients' biopsies lacked sufficient material to accurately stage their cancer, leading to incorrect tumor staging and increased mortality rates.
A new study found that US osteoporosis screening guidelines failed to identify the majority of younger post-menopausal women who experienced major fractures. The guidelines recommended testing and treatment for women aged 65+, but only predicted fractures in around 25% of those aged 50-64.
A new test using DNA sequencing identifies single mutations causing rare genetic disorders in children, improving diagnosis rates from 5% to 40%. The UCLA Clinical Genomics Center uses the test to provide concrete diagnoses and treatment plans for families seeking answers.
Researchers at UCLA have discovered that fibroblasts can transform into endothelial cells, which form blood vessels. This finding suggests a potential new strategy for improving heart repair after a heart attack.
The UCLA Center for Healthier Children, Families and Communities has established a national Health Care Transitions Research Network for individuals with autism spectrum disorder (ASD), focusing on research to improve physical, psychosocial, educational and vocational outcomes for adolescents and young adults with ASD.
Researchers used an epigenetic clock to measure the biological age of liver tissues in obese subjects, finding a significant acceleration of liver aging. The study suggests that obesity may contribute to the premature development of age-related diseases such as liver cancer and insulin resistance.
The University of California, Los Angeles (UCLA) will develop new strategies for mining and understanding complex biomedical data sets. The center's findings will help shape guidelines for future data integration and use.
The UCLA Children's Discovery and Innovation Institute has named three recipients of the inaugural Harry Winston Fellowships, supporting young pediatric physician-scientists conducting research to prevent, treat, and cure diseases in children. Dr. Kristina Adachi, Dr. Leslie Kimura, and Dr. Edward Talya will receive funding for their p...
Researchers found that combining resveratrol with benzoyl peroxide reduces bacteria counts more effectively than either compound alone. The combination treatment may lead to new, less irritating topical acne therapies.
Researchers found that medical students from underrepresented minority backgrounds are more likely to have attended a community college at some point. Additionally, community college students who were accepted to medical school were more likely to commit to working with underserved populations.
Researchers have discovered a link between genetic factors and the development of early-onset ulcerative colitis. The study's findings suggest that phosphatase and tensin homologue (PTEN) may play a role in helping the disease develop, and that altering the gut microbiome could be a key to prevention.
Researchers discovered a peptide mimicking high-density lipoprotein (HDL) protein helps reduce oxidized lipids in pulmonary hypertension, improving heart and lung function. The study also found elevated levels of oxidized proteins in rodents with the disease, which can be targeted for treatment development.
A UCLA study found that men with low prostate cancer knowledge experience increased decisional conflict and lower perceived effectiveness of treatment. Doctors can help by providing educational information before consultations to increase patients' comprehension and reduce regret.
A UCLA-led study discovered a protein called interleukin-32 that helps protect people with latent tuberculosis from developing the active form of the disease. The researchers found that vitamin D levels play a crucial role in this protection, and supplementing with vitamin D may help prevent TB.
A study by UCLA and RAND Health found that providing futile treatment in the ICU sets off a chain reaction, delaying critical care for other ill patients. The study shows that on 16% of days when ICUs were full, one patient received futile treatment, causing others to wait longer for admission.
A new vaccine, rBCG30, offers superior protection against tuberculosis in animal models and cross-protection against leprosy. Boosting rBCG30 with the Antigen 85B protein significantly enhances its effectiveness against leprosy.
A new UCLA-led research study has found that racial and ethnic minorities who receive implantable devices to treat heart failure derive the same substantial survival benefit as white patients. The study, involving over 15,000 patients, monitored two years of data from a registry to improve heart failure therapies in outpatient settings.
A new disposable biosensor may help physicians determine which patients can safely be fed following surgery by monitoring intestinal movements. The device, AbStats, uses sound waves to measure the rate of acoustic events in the intestines, allowing doctors to make evidence-based decisions about post-operative feeding.
A UCLA-led analysis found that changes in treatment over the past decade have associated with higher survival rates for all patient groups, regardless of age or risk factors. The study tracked 6.5 million patients treated for heart attacks between 2002 and 2011 and found improved outcomes with earlier cardiac catheterization
A new UCLA study reveals that California diabetics living in low-income neighborhoods are 10 times more likely to lose a toe, foot or leg than those in affluent areas. The research highlights the need for earlier medical care and expanded access to treatment to prevent amputations.