Researchers found that loggerhead turtles spend an average of seven years and 16 years in the waters off Baja California before migrating to Japan. The study provides crucial information for developing conservation plans and reducing bycatch rates, which can be as high as 1,000 turtles per year.
Researchers discover Ruby Seadragons lack ornate leaf-like appendages, a feature previously considered distinguishing to all seadragon species. They also found that the fish have prehensile, curled tails, similar to those of seahorses and pipefish, which may aid in holding on to objects in high-surge waters.
Researchers at UC San Diego discovered that bacteria in biofilm communities can send long-range electrical signals to recruit new members from different species. This discovery reveals a human-like trait in bacteria, showing that they can exert dynamic control over distant cells through electrical signaling.
Researchers at UC San Diego have documented how large viruses reprogram bacterial cells to resemble animal or human cells, allowing them to mass-produce new viral particles that eventually kill the infected cells. The study reveals a previously unknown mechanism of viral replication in bacteria.
Researchers at University of California San Diego School of Medicine found that one session of moderate exercise can stimulate the immune system, producing an anti-inflammatory cellular response. This benefits individuals with chronic inflammatory diseases such as arthritis, fibromyalgia, and obesity.
Researchers have demonstrated a new type of laser using bound states in the continuum, which can be more compact and energy-efficient. This technology has the potential to revolutionize telecommunications and computing applications.
Researchers at UC San Diego developed practical strategies for building and coordinating balloons within hurricanes, using GPS and cellphone-grade sensors. The approach leverages control theory to distribute balloons horizontally and mitigate turbulence fluctuations, enabling improved in-situ sampling and forecasts.
A team of researchers observed Hawaiian false killer whales removing fish from longline fishing gear for the first time, gaining insight into a behavior that has led to unsustainable entanglements. The study provides new information on the animals' behavior and may lead to the development of 'smart hooks' to reduce bycatch.
Researchers at the University of California San Diego have discovered neurons in the subiculum area of the brain that encode an animal's current axis of travel. These 'axis-tuned' cells fire when the animal travels in either direction along a single line, allowing it to mentally group different locations and navigate complex routes.
Researchers have identified new gene fusions and mutations associated with a subset of GIST patients, providing novel insights into the disease's biology. These findings could lead to personalized treatment approaches and improved outcomes for GIST patients.
Researchers at UC San Diego developed a non-invasive method to detect infections in prostheses using an improved version of electrical capacitance tomography and a thin-film sensor that can detect changes in pH levels. The new method could provide quantitative diagnostic information about the extent and locations of infections.
A recent study discovered that liver cancer drugs fail because the body lacks a balance between two enzymes, Shp2 and Pten. This imbalance activates molecules involved in lipid metabolism, inflammation, and fibrosis, leading to liver disease and cancer.
The study reveals that the square shape provides greater rigidity and higher resistance to ovalization and buckling than a hollow round shape of the same weight. This unique adaptation enables birds to fly with optimized stiffness and lightness, inspiring advanced engineering designs.
Researchers have identified six loci linked to personality traits and found correlations between these traits and distinct psychiatric disorders. Personality factors such as extraversion and neuroticism were associated with specific genetic variants.
Scientists at University of California San Diego determined the 3D structure of CCR2 simultaneously bound to two inhibitors, providing insights for developing anti-inflammatory drugs. The study reveals how these molecules turn the receptor 'off' by blocking natural chemokine binding and preventing inflammatory signal transmission.
Researchers analyzed feeding behaviors of 15 common species of algae-eating fish to understand their role in maintaining coral reef health. The study found that individual species selectively graze on different types of algae and in varying ways.
A new study by University of California San Diego School of Medicine scientists discovered the Hippo pathway's unexpected function in subduing cancer immunity. Deleting LATS1/2 from mouse cancer cells enhanced anti-tumor immune responses, suggesting a potential therapeutic approach to improve immunotherapy efficiency.
Biologists observed the emergence of two distinct virus species within a month-long experiment, leveraging a harmless human virus and two types of bacteria with varying receptors. This rapid process, known as speciation, was previously challenging to study due to its slow pace.
Researchers discovered eight locations in the genome with copy number variants associated with schizophrenia risk, affecting dozens of genes or disrupting single genes. These ultra-rare variants occurred more frequently in genes involved in synapse function and carried a four- to 60-fold increased risk for psychiatric illness.
Scientists at UC San Diego School of Medicine discovered a key protein involved in protecting epithelial cells during stress, and found that the widely prescribed anti-diabetic drug Metformin works by activating this pathway to prevent cancer. The study provides new insights into the mechanism behind Metformin's tumor-suppressive action.
Researchers developed a new method to identify antibiotics hidden in massive mass spectrometry datasets. By running data against a database of known antibiotics, they detected previously unknown compounds and discovered new variants of existing ones. This breakthrough aims to help combat antibiotic resistance.
A new study by researchers at University of California San Diego School found that women choosing to become first-time mothers later in life may increase their chances of living into their 90s. Women who had their first child at age 25 or older were more likely to live to age 90.
Researchers at University of California San Diego School of Medicine found that ustekinumab induces response and remission in patients with Crohn's disease. The study showed high remission rates among patients treated with intravenous or subcutaneous ustekinumab.
Researchers at UC San Diego School of Medicine developed a bioinformatics framework that identified key proteins significantly altered in patients with diabetic kidney disease. The 'MetBridge Generator' framework revealed the protein MDM2 played a key role in disease progression, and its potential as a therapeutic target was discovered.
Researchers used mass spectrometry to detect molecules on phones and skin, creating personalized lifestyle profiles with diet, medication, beauty product usage, health status, and location information. The study has potential applications in crime scene investigations, airport screening, and environmental exposure studies.
Acoustic waves were used to manipulate fluids in nanoslits, enabling the creation of small, portable devices for sorting cells, filtering particles, and sensing biological components. The technology has the potential to revolutionize fields like drug discovery and microrobotics.
Scientists created a nanosensor design that combines three-dimensional plasmonic nanoparticles with exceptional points, enabling enhanced sensitivity and smaller size. The new technology has the potential to revolutionize portable health monitoring and security applications.
Researchers identified a blood test that predicts infant outcomes and classifies FASD subpopulations. The test uses biomarkers in maternal plasma miRNAs to predict infant health.
Researchers at UC San Diego have fabricated a semiconductor-free microelectronic device using metamaterials, showing a 1,000% increase in conductivity. The discovery paves the way for faster and more powerful devices, as well as more efficient solar panels.
Researchers found that people living at high altitudes with chronic mountain sickness produce significantly more red blood cells than those without the condition. This is due to an overproduction of the SENP1 enzyme, which boosts levels of other proteins promoting cell division and survival.
Researchers at University of California San Diego developed a new form of multicolor electron microscopy allowing simultaneous visualization of multiple molecular species. This technique reveals details and processes not visible in grayscale images, providing new insights into cellular ultrastructure.
A team of researchers at UC San Diego School of Medicine successfully reversed diabetic insulin resistance and glucose intolerance in mouse models by removing the protein galectin-3 (Gal3). This finding suggests that Gal3 inhibition could be an effective way to treat type 2 diabetes.
The roadmap advocates for research efforts in human-robot interaction to develop intelligent machines that empower people to stay in their homes as they age. It also highlights the need for flexible robotics systems to accommodate customization in manufacturing and other areas.
A Scripps-led study found a positive association between flu outbreaks and absolute humidity across all latitudes, with a critical temperature window of 70-75 degrees Fahrenheit. Researchers suggest using humidifiers in dry climates and dehumidifiers in tropical regions to control the spread of the virus.
Researchers create self-healing batteries, sensors and wearable circuits using a special magnetic ink. The devices can repair tears as wide as 3 millimeters in under 50 milliseconds.
A new study identifies the Hedgehog signaling pathway as a central driver of gastrointestinal stromal tumors (GIST), which are often resistant to current treatments. Researchers have found that targeting this pathway with arsenic may offer a new approach to treatment, potentially killing multidrug-resistant cell lines.
A study of 12 million Facebook users found that using the platform is associated with living longer, particularly for those who maintain real-world social ties. Moderate online activity complements offline interactions, while excessive online time is linked to a higher risk of mortality.
Researchers discovered CD98 promotes AML, a type of aggressive cancer, and inhibiting it with the anti-CD98 antibody IGN523 blocks AML growth in patient-derived cells and mouse models.
Researchers developed a way to integrate multiple big data sets from biology to understand cellular processes, discovering new regularities and biological consistencies. The study found pause sites dictate protein structure and folding, providing insights into cancer biology.
A study found that long-duration spaceflight weakens the muscles supporting the spine, leading to increased back pain and disc disease. Researchers suggest exercise countermeasures like core-strengthening exercises and yoga may help prevent muscle atrophy and improve spinal function.
Researchers discovered that cytomegalovirus (CMV) hijacks the molecular machinery in human cells to survive and replicate, relying on the human protein CPEB1. Suppressing CPEB1 levels during CMV infection reverses harmful cellular changes and reduces viral production tenfold.
Researchers discovered damage to RNA-binding protein hnRNP A2/B1 contributes to ALS by scrambling cellular messaging systems. The study provides a new therapeutic target for treating the disease.
Researchers discovered that Zika virus infection leads to modifications of both viral and human genetic material, including the addition of methyl groups. This alteration affects viral replication and the human immune response, highlighting the importance of methylation in vaccine and therapy development.
Researchers found significantly more nitrate-reducing microbes in the oral samples of migraine sufferers compared to non-migraineurs. The study suggests a potential connection between these microbes and migraines, though it remains unclear if they are a cause or result.
The NIH has expanded its Precision Medicine Initiative Cohort Program to California, partnering with eight regional medical centers. The program aims to engage one million or more US participants in a longitudinal research effort to improve disease prevention and treatment based on individual differences.
Researchers found that depriving brain tumor cells of cholesterol specifically kills them and causes tumor regression. This alternative method targets glioblastomas, the most aggressive form of brain cancer, which are difficult to treat due to their biochemical composition and blood-brain barrier.
Researchers have confirmed that mutation-caused dysfunction in a process cells use to transport molecules within the cell plays a previously suspected but underappreciated role in promoting Alzheimer's disease. The study found that treating mutated neurons with a beta-secretase inhibitor rescued endocytosis and transcytosis functions.
Researchers developed a novel method to quantify NAFLD progression to advanced fibrosis and cirrhosis. The technique combines multiple non-invasive measures, including heavy water labeling and MRI assessments, to predict individual clinical fibrotic disease progression.
Scientists at the University of California - San Diego designed a device that harnesses light to manipulate its mechanical properties. The device oscillates indefinitely using energy absorbed from light, enabling new applications in GPS, computers, and other devices.
A new fault has been identified in the Salton Sea area of Southern California, which could impact current seismic hazard models and earthquake risk assessment. The discovery provides much-needed information on the intricate structure of earthquake faults beneath the sea and may offer new insights into the region's earthquake cycle.