Women's sexual satisfaction is linked to their overall quality of life and perception of successful aging, even as physical health declines with age. Approximately 67% of women reported being moderately to very satisfied with their sex lives across different age groups.
Researchers have discovered a novel cytokine, Interleukin 37 (IL-37), that protects mice from colitis by modulating inflammation. This finding offers a promising approach to treat or control overactive immune systems in humans, particularly for patients with inflammatory bowel disease.
A study by UCSD researchers reveals a rapid increase in hookah use among California youth aged 18-24, with most users smoking with friends. Hookah is perceived as a safer alternative to cigarettes despite being less healthy, prompting calls for laws to ban hookah lounges.
Researchers measured a spike in radioactive sulfur in the air, revealing that 400 billion neutrons were released per square meter surface of cooling pools between March 13 and March 20, 2011. The levels reached California coast, but posed no threat to human health.
Cabo Pulmo National Park has proven to be the world's most robust marine reserve, with a 463% increase in fish biomass from 1999 to 2009. The park's 'no take' restrictions and local enforcement have been key factors in its success.
Gordon, a high-performance supercomputer using large amounts of flash-based SSD memory, is being made available to US academic researchers. The system will handle massive databases with up to 100 times faster speeds than traditional hard drive disk systems.
A new experimental study from the University of California, San Diego suggests that spoilers don't spoil stories, but rather enhance enjoyment. People who flip to the last page before starting a book have better intuition and prefer spoiled versions of ironic-twist and mystery stories.
Researchers have discovered a way to prevent light signals from reflecting backwards on silicon chips, enabling faster data transfer rates and lower costs. The breakthrough could lead to the development of integrated photonic chips that replace electronic chips in information technology.
A study by UC San Diego researchers found that convenience-driven choices account for 36-51% of a child's daily caloric needs, with meals providing over 50% of recommended sodium intake. The study highlights the need to educate families on making healthier decisions when dining at fast-food restaurants.
A UC San Diego study found that mimicking someone's body language can incur a reputational cost in certain situations. In real-life interactions, people are often observing others' mirroring behavior, which can negatively impact their perception of the person doing the mirroring.
A new study has identified possible genetic variations that could influence a patient's recovery from an eating disorder. The findings suggest that certain genetic traits, including those associated with anxiety and concerns over mistakes, may be linked to chronic eating disorders.
The University of California, San Diego has received a major $18 million grant to further develop the science of glycobiology. The grant will focus on training scientists fluent in glycan chemistry and biology to study how glycans modulate inflammatory responses and fund collaborative projects.
A new study by UC San Diego researchers found that solar photovoltaic panels can cool buildings by up to 5 degrees Fahrenheit, reducing cooling costs by 5% over the panels' lifetime.
A novel combined therapy has been developed to treat brain cancer patients with neoplastic meningitis, a devastating neurological complication. The treatment involves delivering chemotherapy directly to the brain's surfaces while draining excess spinal fluid to alleviate pressure and improve quality of life.
A team of researchers led by Ayse Pinar Saygin found that the human brain responds with a mismatch in perception when an android's appearance and motion are at odds. This phenomenon, known as the 'uncanny valley,' occurs when an artificial agent becomes too human-like, causing discomfort and unease.
Researchers at UCI have found a new method for predicting how influenza proteins evolve, allowing for potential pharmaceutical exploitation. This approach could aid the development of new drugs targeting so-called 'flu protein pockets'.
Scripps researchers identify a new force driving Earth's massive tectonic plates, finding that plumes of hot magma from the deep interior play a crucial role in shaping the planet. This 'plume-push' mechanism has been linked to significant geological events, including the formation of volcanoes and the movement of continents.
Researchers found that women are more likely to survive after gastrointestinal surgeries than men, particularly those before menopause. Female patients had lower mortality rates in various procedures, suggesting that female hormones may enhance the immune system.
A Scripps study found 9.2% of mid-water fish contained plastic debris, primarily small pieces smaller than a human fingernail, in the North Pacific Subtropical Gyre. The researchers estimate tens of thousands of tons of debris are ingested by fish annually.
Researchers found evidence of coincident timing between ancient Salton Sea flooding and fault rupture, potentially triggering large earthquakes on the southern San Andreas Fault. The study suggests heightened preparedness for a major quake immediately following smaller quakes in the stepover zone is warranted.
Researchers found a weakened ability to sync brain hemispheres in toddlers with autism, which could lead to earlier diagnoses and treatment. The study used fMRI scans on sleeping toddlers and identified language areas with reduced synchronization.
A team of scientists used induced pluripotent stem cells from patients with inherited ALS to reveal how reduced VAPB protein levels contribute to the disease. The study provides a novel in vitro model of ALS and offers an unprecedented opportunity to answer questions about the disease's pathogenesis.
A team of scientists has uncovered a novel mechanism regulating gene expression and transcription linked to Spinocerebellar ataxia 7, an inherited neurological disorder. Non-coding RNA plays key role in neurological development and function.
A study published in Addiction journal finds that even low levels of blood-alcohol content are associated with severe injuries and death. The research suggests that buzzed drivers are more likely to speed, be improperly seat-belted, and drive at greater speeds, leading to increased accident severity.
Researchers at UC San Diego developed a method to disguise nanoparticles as red blood cells, allowing them to evade the immune system and deliver cancer-fighting drugs directly to tumors. This breakthrough could lead to more personalized drug delivery, reducing the risk of immune response.
Researchers have uncovered a crucial survival response in the body's immune system to deadly anthrax infections. The study found that a key signaling molecule ATP is released from infected macrophages to alert other immune cells, triggering a complex pathway to combat the bacteria.
Researchers at UCSD identified a tumor inflammation trigger common to most cancers, which can be blocked by inhibiting a single protein. This inhibition reduces primary tumor growth and halts tumor progression and metastasis in animal studies.
Researchers at UCSD have discovered a novel signaling pathway and gene, Wnt16, essential for the formation of hematopoietic stem cells in vertebrate embryos. This breakthrough has significant implications for developing stem cell-based therapies for diseases such as leukemia.
A new phase-change memory-based 'Moneta' system offers unprecedented performance, with read speeds up to seven times faster than current SSDs. The device uses PCM technology to store data in a metal alloy, providing lower latency and reduced energy requirements for high-performance computing applications.
Researchers have discovered a potential new therapy for Alzheimer's disease, with the cysteine protease inhibitor E64d improving memory deficits and reducing β-amyloid build-up. The study suggests that increasing Cathepsin B activity is not detrimental to memory function, contrary to previous assumptions.
A new biomaterial more closely mimics native human tissue, exhibiting negative Poisson's ratio and maintaining its shape when stretched. The breakthrough enables the creation of biocompatible tissue patches for repairing damaged heart walls, blood vessels, and skin.
The West Coast high-frequency radar network, operated by Scripps Institution of Oceanography, provides kilometer-scale current observations out to 150 kilometers offshore and 2,500 kilometers of shoreline. This network allows for the determination of geographic differences in coastal surface circulation and characterization of phenomen...
Scientists uncover a highly conserved dual mechanism that regulates both brain development and function across diverse species. The discovery could lead to biomarkers for neurological diseases and potentially cure them with microRNA therapeutics.
Research shows that eating triggers anxiety in individuals with anorexia nervosa, rather than the expected feeling of pleasure. The study uses brain imaging technology to demonstrate a paradoxical response to food in people with the disorder, highlighting the need for effective treatment strategies.
The California Energy Commission is funding $1.4 million in renewable energy research at UC San Diego, including advanced solar forecasting and energy storage systems. The investment will help accelerate the development of clean energy technologies and achieve California's 33% Renewable Energy Portfolio Standard by 2020.
A human gene implicated in leukemia also acts to prevent cancer of the liver by producing an enzyme called Shp2, which protects hepatocytes from toxic damage. Conversely, this same enzyme is a known factor in the development of several types of leukemia.
A new study from UCSD School of Medicine reveals the plasticity of some gene expression programs, allowing for alternative induced gene expression. This plasticity may contribute to cancer cell growth and normal differentiation, with implications for hormone therapy.
Researchers at UC San Diego found that induced pluripotent stem cells could be rejected by the immune system, challenging their potential as a promising means to develop stem cell therapies. The study suggests that iPSCs are subject to some of the same problems of immune system rejection as embryonic stem cells.
Researchers found that a steroid hormone called ADIOL moderates inflammation in the brain and may lead to new treatments for patients with neurodegenerative conditions. The discovery could also help predict risk or responses to drugs that mimic its actions.
A study led by Subhojit Roy reveals how certain proteins in neurons travel at a slower pace than others, assembling into larger complexes that move down the axon. The proposed model suggests a 'plume' of proteins, where complexes disassemble and reassemble as they progress, making the overall motion slow and coordinated.
Researchers at UC San Diego and Scripps Institute of Oceanography used matrix-assisted laser desorption ionization mass spectrometry to reveal multiplex microbial interactions. The technique allowed them to see competition for resources, secretion of molecules altering neighboring organisms' phenotypes.
A team of researchers has deciphered the genome of a tropical marine organism, Lyngbya majuscula 3L, which produces substances with biomedical promise. The study provides insights into the genetics underlying their production and reveals key information about its limitations and shortcomings.
A study by researchers at UC San Diego finds that Filipino children are more likely to develop aneurysms and inflammation of the blood vessels of the heart compared to other Asian and non-Asian backgrounds. The research highlights the need for medical providers to be aware of Kawasaki disease in high-risk populations.
Researchers have developed a new material sensor that can detect when carbon filters in respirators become saturated with toxic vapors, providing a more accurate warning for emergency workers. The sensor uses photonic crystals made of carbon nanofibers, which change color as the filter absorbs chemicals.
A new method developed by researchers at the University of California, San Diego School of Medicine has revealed functional gene networks in a live organism. The technique allows for the prediction of gene functions and could be useful for understanding human disease.
Researchers at the University of California, San Diego, developed a novel screening approach to detect Autism Syndrome Disorder (ASD) in babies at 1-year check-ups. The 'One-Year Well-Baby Check Up Approach' has shown a positive predictive value of 75% using a simple, five-minute screening technique.
Biologists at UC San Diego discovered that electrical oscillations are critical for the brain to store spatial memories. Grid cells in the entorhinal cortex require precise timing of electrical oscillations to function properly, suggesting a key component in memory processing.
Researchers have identified potential human molecular targets of Nelfinavir, an anti-HIV drug also effective as a cancer therapy. The study suggests that the collective effect of weak interactions with multiple protein kinases leads to clinical efficacy.
Researchers at University of California - San Diego School of Medicine and colleagues report a game-changing advance in stem cell science: the creation of long-term, self-renewing neural precursor cells from human embryonic stem cells that can be directed to become many types of neuron. The new process promises to have broad applicatio...
The San Diego Supercomputer Center is launching a new data-intensive supercomputer system named Gordon, which will have 250 trillion bytes of flash memory and 64 I/O nodes. This new system aims to solve the challenge of storing valuable data and accelerating scientific discovery by providing faster speeds and massive storage capabilities.