Scientists have found that nearly all antibiotic resistance genes came from bacteria that cause disease, not antibiotic-producing bacteria. The rapid evolution of resistance is fueled by the use and overuse of antibiotics, threatening modern healthcare.
A new drug combination using Selinexor and Nutlin-3a has shown promising results in increasing susceptibility to chemotherapy in cases of severe neuroblastoma. The treatment targets the p53 gene mutation, which is rare in neuroblastoma but present in other cancer forms.
A University of Gothenburg study reveals that male managers are more likely to hold negative attitudes toward depression, especially in senior positions. The research, which surveyed over 2,600 managers in Sweden, found that female managers had a significantly lower proportion of negative attitudes towards the mental disorder.
A large study of over 2,300 patients found that paclitaxel-coated balloons and stents do not increase mortality rates compared to conventional devices. The results resolve a long-standing debate on the safety of these treatments for peripheral arterial disease.
A meta-analysis of three randomized studies found that induction at 41 weeks reduces perinatal death and morbidity compared to expectant management until 42 weeks. For first-time mothers, this approach results in a lower risk of severe illness or death in babies.
A study of extinct bird species reveals that flightlessness developed in many cases due to human impact, with 29% of extinct species lacking the ability to fly. The researchers found that if humans had not caused some extinctions, there would be over 150 independently developed flightless bird groups.
A new study suggests that the climate in inner East Asia has reached a tipping point, where recent hot and dry summers may be irreversible. The study used tree rings to reconstruct changes in soil moisture and frequency of heat waves, revealing that the region has not seen these conditions in over 260 years.
Researchers at the University of Gothenburg have discovered a connection between Brachyspira bacteria and IBS, particularly the form causing diarrhea. The study found that Brachyspira was present in 31% of IBS patients, with symptoms often resembling an allergic reaction, sparking hopes for new treatments.
A European study confirms that altered intestinal microbiota increases the production of imidazole propionate, a molecule that prevents insulin's blood sugar-lowering effects. Elevated levels of imidazole propionate are also found in prediabetes, suggesting it may contribute to disease progression.
A University of Gothenburg study found that continuous glucose monitoring (CGM) has favorable effects over several years, including a 4 mmol/mol decrease in average blood glucose levels and a 70% reduction in episodes with low blood sugar levels. Patients also reported improved comfort and reduced anxiety.
A study of 444 patients in Sweden found that prescription physical activity improved weight, blood pressure, and quality of life, particularly among those with low initial activity levels. Continuous support and individualized treatment were crucial for maintaining gains over two years.
A study in Malawi reveals that financial support for households and cooperation with local authorities are crucial for successful Covid-19 restrictions. Survey respondents found that social distancing measures were more compliant due to lower individual costs.
A University of Gothenburg study shows that a molecule from gut bacteria, imidazole propionate, reduces the efficacy of metformin in lowering blood glucose. The study found high levels of imidazole propionate associated with impaired metformin action in type 2 diabetes patients.
A University of Gothenburg study reveals that survivors of the 1988 Halabja poison-gas attack struggle with uncertainty about survival, forming couple relationships, and having children due to CWAs exposure
Researchers from the University of Gothenburg found that COVID-19 patients with brain impairment had elevated immune activation markers, but no viral presence in cerebrospinal fluid. This suggests that the patient's immune response may be the underlying cause of neural damage.
A University of Gothenburg study finds that individuals who undergo obesity (bariatric) surgery have a higher average life expectancy compared to those given conventional treatment for obesity. The study, published in The New England Journal of Medicine, shows that bariatric surgery prolongs life expectancy by 3 years, but patients sti...
An elderly population study from Sweden found a higher risk of suicide among women born outside the Nordic region with untreated depression. The study also highlighted gender differences in factors related to suicide, including the protective effect of marriage in men and social isolation in both genders.
Researchers analyzed surgical outcomes in Swedish cataract surgeries from 2007-2016, finding that high-volume surgeons had a lower proportion of severe cases and complications. The study suggests that surgeons can improve patient safety by understanding the impact of case mix on outcomes.
A University of Gothenburg study emphasizes the importance of a systematic approach to achieve person-centered care in healthcare. The researchers argue that person-centred care must be practiced systematically on an everyday basis, creating organisational and individual conditions for partnership between patients, staff, and relatives.
A new study finds that human impact is responsible for 96% of all mammal extinctions over the last 126,000 years. The research suggests that mammals were resilient to extreme fluctuations in climate and that current climate change poses a significant threat to species
A Swedish study of 381 patients with low-grade brain tumors found that just 28% returned to full-time employment within a year. Factors associated with lower return rates included advanced age, functional level, and previous sick leave.
A University of Gothenburg study shows that units outside emergency healthcare are willing to assist in a crisis, including hotels, schools, and veterinary clinics. The 'flexible surge capacity' (FSC) system aims to scale up emergency care during surges in patient numbers.
Researchers have found that an individual's gut microbiota can predict and treat type 2 diabetes, with altered gut bacteria linked to reduced butyrate production. The study suggests potential for personalized dietary changes or probiotics to prevent or treat the disease.
Using highly novel techniques, researchers observed upper ocean currents of approximately 0.1-10 km in size, critical for controlling heat and carbon movement between the ocean and atmosphere. These findings contribute to improving our understanding of small-scale ocean and climate processes with impacts globally.
A study from University of Gothenburg found that COVID-19 patients with moderate to severe symptoms exhibited brain injury signs, including elevated GFAP and NfL biomarkers. These biomarkers were also associated with disease severity and ventilator treatment.
Cholesterol levels have dropped sharply in high-income nations like those in North-western Europe, North America, and Australasia, but risen in low- and middle-income countries, particularly in East and Southeast Asia. High cholesterol is responsible for approximately 3.9 million worldwide deaths annually.
The study found that statin therapy was associated with a decrease in the prevalence of Bact2 enterotype, which is linked to inflammatory bowel disease and depression. The researchers suggest that statins may be used to alter the gut microbiota, leading to new treatment options for cardiovascular disease.
A study of over 160,000 participants in 27 countries found that women have a more favorable risk pattern for cardiovascular disease. Women had lower blood pressure and healthier blood fat levels, and were less likely to smoke, which contributed to their lower risk of heart disease.
A study of over 73,000 people in 33 countries found that four out of ten adults worldwide have functional gastrointestinal disorders. The disorders, which include symptoms like heartburn and irritable bowel syndrome, were more prevalent in women and associated with lower quality of life.
A new study from the University of Gothenburg finds that weighted vests can lead to a reduction in body weight and fat mass, particularly when wearing heavy weights, while maintaining muscle mass. The researchers suggest that this is due to a built-in energy balance system that endeavors to keep body weight constant.
A study published in Journal of Internal Medicine found that men with a history of obesity in their late teens are more at risk of developing blood clots (venous thromboembolism) in adulthood. The risk increases progressively, with severe obesity associated with a nearly fivefold higher risk.
A new blood test has been developed to detect Alzheimer's disease, which measures a specific variant of tau protein in ordinary blood samples. The test shows great promise for diagnosing and monitoring the condition early on, particularly in primary care settings.
A study at the University of Gothenburg found that wind turbine noise influences people's perception of restorative effects of sleep and has a small but significant effect on dream sleep. Participants who lived near wind turbines reported worse sleep quality during quiet nights.
A new antibiotic resistance gene, gar, has been discovered in environmental samples from India and found in several clinical pathogens, including Salmonella and Pseudomonas. This rare gene provides resistance to aminoglycoside antibiotics, which is concerning for treating multi-resistant bacteria.
A Swedish study has found that abdominal arterial aneurysm is associated with elevated subtypes of white blood cells in older men. Quitting smoking also appears to positively impact the disease's course.
A new experimental platform for cancer diagnostics, prognoses, and testing cancer drugs has been developed by analyzing the extracellular matrix of tumor tissues. The platform uses protein fibers surrounding cells to predict disease risk and potential treatment efficacy in various patients with different types of cancers.
Researchers outline hands-on guidelines to utilize machine learning in studying active matter, emphasizing data preprocessing and physics-informed models. The field offers advantages in acquiring high-quality data and tracking system dynamics over long time scales.
Researchers found that glacier ice walls block warm seawater, preventing melting and raising global sea levels. The findings provide better tools to predict future water levels and create more accurate climate prognoses.
A new study from the University of Gothenburg shows that structured and preventive care can significantly reduce the risk of recurrent fractures. The study found that patients who received fracture liaison services had an 18% lower risk of having another fracture compared to those without these services. This reduction in risk was attr...
A new study from the University of Gothenburg shows that bariatric surgery is as effective for individuals who developed obesity early in life as it is for those who developed it later. The study found no difference in weight loss or obesity-related complications between the two groups.
A new method predicts how extreme climate events affect energy systems with a focus on renewable energy sources. Future climate events can have a considerable impact, leading to power supply reliability reductions of up to 16%. Collaboration between energy system experts and climate researchers is necessary for optimization.
A University of Gothenburg study reveals that menopausal age is unclear for many women, particularly those using hormonal birth control. Researchers found that after 1992, the number of women still menstruating decreased, leaving uncertainty in determining exact menopausal ages.
Scientists at University of Gothenburg discovered a new species of antibiotic-resistant bacteria, Scandinavium goeteborgense, isolated from an infected wound. The bacteria exhibit novel genetic variants of resistance, highlighting the need for precise treatment choices.
A new study suggests that human-caused biodiversity decline started millions of years ago, with early hominins competing with carnivores for food. The researchers propose that human ancestors stole recently killed animals from other predators, leading to the extinction of large carnivore species in East Africa.
A recent study by the University of Gothenburg found that many 70-year-olds in Sweden overestimate their eyesight, but can still see considerably better with glasses or power correction. The study also highlights the importance of regular eye exams to detect visual impairment and age-related diseases.
A study published in JAMA Dermatology found that bariatric surgery significantly reduces the risk of malignant melanoma and other skin cancers in severely obese individuals. The study, which followed over 2,000 participants, showed a 57% decrease in malignant melanoma risk for those who underwent bariatric surgery.
A new study reveals that molecular chaperones play a crucial role in preventing the misfolding of alpha-synuclein protein, which is associated with diseases like Parkinson's. By inhibiting these chaperones, researchers found that alpha-synuclein aggregates can form at the amino acid level.
Researchers discovered a connection between gastric bypass surgery and the release of glucagon-like peptide-1 (GLP-1), a hormone regulating appetite. The study found that mHMGCS, an enzyme triggering ketone body formation in the small intestine, inhibits GLP-1 release.
A Swedish study of 2,760 women found that induction of labor after 41 full gestational weeks resulted in no deaths, whereas six cases of perinatal death were recorded when labor was waited for until 42 weeks. The study suggests a safer alternative for mothers and babies.
A phase I/II study of the Swedish vaccine candidate ETVAX found it to be safe and broadly immunogenic, inducing impressive immune responses in young children and infants. The vaccine showed high response rates among children aged 2-5 years and infants, with some even showing enhanced immune responses when given with an adjuvant.