Researchers developed a novel urine test to diagnose adherence to blood pressure medications, finding that nearly 40% of patients fail to take prescribed medication. Younger patients and females are at higher risk of non-adherence.
University of Leicester astronomers' predictions of Jupiter's planetary phenomena have been confirmed by the Juno mission. The spacecraft has revealed an even more extreme environment than predicted, with intense radiation belts and powerful aurorae.
A ground-breaking study suggests that a non-invasive post-mortem technique could be used to identify the cause of death in up to 92% of adult post-mortem investigations, potentially replacing invasive autopsies. The technique, known as PMCTA, uses computed tomography and angiography to diagnose causes of death with high accuracy.
Researchers at University of Leicester discovered that the Earth's mantle is divided into two large domains that convect independently, with limited mixing between them. Upper mantle material flows to lower parts of the mantle when it reaches a subduction zone, maintaining separate domains.
Researchers from the University of Leicester and University Hospitals of Leicester NHS Trust have reported outstanding results from a long-term follow-up study on patients with CLL. The study, which used a selective BTK inhibitor, showed durable remissions without new toxicities in most patients.
Researchers at the University of Leicester have discovered a massive, cold spot on Jupiter's atmosphere, comparable to its famous Great Red Spot, generated by polar aurorae. The phenomenon, potentially thousands of years old, creates a region of cooling in the thermosphere and has been observed to change dramatically over time.
The Anthropocene Working Group addresses geological critics' concerns about a new epoch, emphasizing the presence of distinctive strata. The group's research highlights human-driven transformations with physical evidence, such as artificial radionuclides and plastics.
Scientists have discovered a 430 million-year-old crustacean fossil, named Cascolus ravitis, in recognition of Sir David Attenborough's contributions to natural history. The exceptionally well-preserved fossil reveals details about the animal's body plan, limbs, and respiratory-circulatory physiology.
A University of Leicester study found that folinic acid can protect neurons in fruit flies with Parkinson's disease, offering potential hope for people with early-onset forms of the condition. The researchers believe that supplementing folinic acid could be a faster and more effective treatment option than developing new drugs.
Research discovered that black carbon alters bacteria's ability to survive and combat antibiotics, increasing the risk of infection. The study also found that air pollution can change the way bacteria behave and cause disease.
A research team led by the University of Leicester identified a breakthrough in the cause of airway narrowing in severe asthma cases. The study found that an active form of key protein HMGB1 is increased and related to airway narrowing.
A recent study by the University of Leicester found that a widely used exercise test for aortic stenosis has a 60% accuracy rate, leading to thousands of unnecessary open heart operations. The test recommends valve replacement therapy for those who become breathless during the test, but actual symptoms may not develop within a year.
Researchers at the University of Leicester have discovered a genetic 'switch' called ATF4 that plays a key role in Parkinson's disease. By targeting this gene, they hope to develop tailored interventions that can prevent or delay neuronal loss.
Scientists have developed a model to predict the chances of developing COPD, a deadly lung disease, based on genetic variations and smoking habits. The study, involving over 350,000 participants from 13 countries, has identified new genetic variants associated with enhanced or worsened lung function in smokers and non-smokers.
Scientists have discovered a new species of 'unfossilizable' loriciferans, a type of animal so small it was considered impossible to find fossils of. The fossils date back to the late Cambrian Period, around half a billion years ago, and provide insight into early animal evolution and ecosystem diversity.
A new study by University of Leicester researchers has identified the mechanism behind solidification cracking in steel welding, a critical engineering alloy. The team used synchrotron X-ray beamline technology to observe crack formation in real-time, revealing micro-porosities as the primary cause.
Researchers found statins reduce venous thromboembolism (VTE) risk by 15-25%, providing evidence for its potential protective effect. A comprehensive review of 36 studies involving over 3.2 million people supported this finding.
Researchers found that increasing niacin levels boosts NAD compound for energy generation and DNA repair, potentially protecting against Parkinson's. The study suggests repurposing cancer drugs to protect faulty mitochondria in Parkinson's disease.
A new class of drugs targeting a specific protein receptor has shown promising results in improving cognitive function and extending the life-span of terminally ill mice with neurodegeneration. The study provides hope for developing effective treatments to alleviate symptoms and slow disease progression in Alzheimer's patients.
Researchers estimate technosphere mass at 30 trillion tons, exceeding biotic species. Human-made structures and waste now outnumber living organisms on the planet.
An international team has made a breakthrough by trapping an intermediate in the mechanism of heme peroxidase enzymes and determining its structure using neutron beams. This finding could change our understanding of how these enzymes work, shedding new light on their role in biochemical processes.
Researchers discovered a genetic link between abdominal aortic aneurysm and four genes, which could help doctors understand the condition better. The study found that early detection is key to preventing fatal internal bleeding, and a new research programme will investigate the effect of these genes on AAA growth.
The study found that neurons fire to relatively few concepts, which tend to be largely related. Internet searches were used to establish degree of association between concepts and show that these associations are encoded by neurons in memory areas.
An international team of researchers observed how a single two-atom-large molecule rotates in the coldest liquid known in nature. By applying pressure, the molecules cooled down their rotations at a rate of over 100 billion degrees Kelvin per second.
An international team has developed a new method to analyze RNA structures linked to cancer. The research aims at understanding how four-stranded RNA structures called G-quadruplexes affect cellular processes such as RNA splicing, which is essential for producing proteins.
In a study by University of Leicester researchers, male stickleback fish change the design of their nests depending on oxygen content, while females also adjust their nest preferences accordingly. This flexibility might give sticklebacks an advantage in rapidly changing environments.
Researchers have identified a protein called PP5 that is significantly upregulated in the lungs of severe asthmatic patients, blocking the effectiveness of anti-asthma drugs. This discovery provides a potential new target for developing novel treatments for severe asthma.
Researchers develop novel technique that combines fluorescent dyes and human skin cells to analyze toxic chemicals. The method provides high accuracy and could reduce the use of laboratory animals in biomedical research.
Researchers found that patients with lower severity trauma have peaks in mortality probability around 14 and 21 days after admission. The study used the largest trauma database in Europe to analyze 165,559 trauma cases, including 19,289 with unknown outcomes.
A new study published in Meteoritics & Planetary Science reveals that mineral veins on Mars were formed by the evaporation of ancient lakes. The research, conducted by scientists from The Open University and University of Leicester, found that the fluids present in Martian Yellowknife Bay were habitable by Earth standards.
A study led by the University of Leicester found that a new asthma pill called Fevipiprant significantly reduced symptoms and improved lung function. The drug was shown to decrease inflammation and repair airway linings, offering hope for severe asthma sufferers.
Researchers at NPL and University of Leicester publish paper showing a new method to calculate spacecraft position using pulsars, increasing space mission capabilities and autonomy. The technique can achieve accuracy of 2km in one direction and 30km in 3D with minimal Earth contact.
A new study by the University of Leicester has identified details in fossil vertebrate eyes that shed light on how vertebrates evolved their complex eyes. The research shows that ancient species of hagfish could see, while living counterparts are blind, revealing a 'reverse evolution' process.
A study by University of Leicester criminologists found that Mobile Scan and Pay technology promotes ease of theft by removing human contact in the shopping process. The report also shows that retailers could be seen as making theft easier for some customers, who may feel justified in committing crime.
A team of researchers from the British Museum and University of Leicester has discovered new evidence in the Caribbean that reveals a complex interplay between early European colonizers and Native Americans. The findings, published in Antiquity, provide a nuanced understanding of cultural identity formation in the Americas.
Researchers at the University of Leicester found that hospital admissions for hypoglycemia have risen by 39% between 2005 and 2014, with almost 80,000 people admitted. The average cost per admission is estimated to be £1,000, with the total cost of treating severe episodes in the UK around £13 million.
A new education program has been shown to reduce the risk of type 2 diabetes in people at high risk by over 80%. The program, which includes a main session and follow-up sessions, resulted in an 88% risk reduction for those who attended fully.
A recent European Commission-funded study examines how children in European countries are influenced by online marketing, revealing significant impacts on purchasing behavior. The study found that all popular online games and half of mobile apps contain embedded advertisements, often not understood by child consumers.
New high-resolution maps and images of Jupiter showcase the planet's dynamic atmosphere, including giant storms and vortices. These observations will help set the scene for Juno's close-up views of Jupiter and provide a global context for its thermal structure, cloud cover, and gaseous species.
Researchers found that neurodegeneration in Parkinson's disease stems from endoplasmic reticulum stress rather than mitochondrial failure. ER stress prevents neurons from producing vital proteins, leading to their death. By blocking ER stress, scientists were able to prevent neurodegeneration in mutant flies.
Key findings from a conference on Émigré Sculptors in Britain reveal that many iconic works were created by European immigrants. The majority of the most eminent sculptors working in Britain were from continental Europe.
A new study by Eric Akobeng reveals that international remittances have a significant impact on reducing poverty and inequality in Sub-Saharan Africa. The findings suggest a 10% increase in remittances as share of GDP leads to a decline in the number of people living on less than $1.25 per day, extreme poverty, and inequality.
Researchers at the University of Leicester aim to develop a test using portable nanopore DNA sequencers to identify species at crime scenes in under an hour. This technology has the potential to combat wildlife trafficking by detecting traces of endangered species, such as elephant and rhino blood.
A major global study has identified a safer treatment for acute stroke, revealing that a modified dosage of the controversial clot-busting drug rtPA can significantly reduce serious bleeding in the brain while improving survival rates. The trial involved over 3,000 patients in 100 hospitals worldwide and showed promising results.
Researchers have identified a unique chemical signature for the ripening of mangoes, allowing for non-destructive assessment of fruit maturity. The discovery has potential applications in developing small devices to detect fruit ripeness, reducing waste and improving market efficiency.
A team of researchers has solved the three-dimensional structure of a gene repression complex, known as the NuRD complex, which plays a role in cancer. The study provides unprecedented detail about the interaction between its components and may help develop strategies to reduce the activity of the complex and combat cancer.
A University of Leicester study found that people with Type 2 diabetes wait an average of 3.7 years for increased treatment, leading to a failure to achieve tight blood sugar control. Clinical inertia is being identified as the major contributor to this issue.
A team of researchers at the University of Leicester has made significant progress in understanding the role of inositol phosphate molecules in regulating gene expression. By developing a novel peptide-based inhibitor, they have gained insights into how enzymes are activated by these small molecules, paving the way for more specific an...
A lab-based study led by University of Leicester researchers has found a way to 'reverse' symptoms of neurodegenerative diseases like Parkinson's and Alzheimer's using genetic and pharmacological approaches. The study utilized fruit flies to explore the role of specific metabolites in the kynurenine pathway, which can help alleviate sy...
The University of Leicester is launching a satellite project to monitor Kenya's forests in near real-time, helping forest land owners and national agencies protect biodiversity and reduce climate change. The project aims to support participatory forest management strategies and enable Kenya to manage its forests more sustainably.