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Uppsala University


Our genes affect where fat is stored in our bodies

A recent study from Uppsala University found that genetic factors play a significant role in determining where fat is stored in the body. The researchers identified nearly 100 genes that affect distribution of adipose tissue to different compartments, with women showing stronger associations than men.

SourceUppsala University·JournalNature Communications·DateJan 21, 2019

Simple method rescues stressed liver cells

Scientists from Uppsala University have devised a simple method to rescue stressed liver cells by temporarily reducing cellular stress. This approach allows suboptimal human hepatocytes to be revived with restored functionality, increasing the availability of high-quality cells for laboratory experiments.

SourceUppsala University·JournalArchives of Toxicology·DateDec 21, 2018

Gigantic mammal 'cousin' discovered

Researchers at Uppsala University discovered a new species of gigantic dicynodont, Lisowicia bojani, in Poland. The species is estimated to be around 4.5 meters long, 2.6 meters high, and weigh 9 tons, making it the largest non-dinosaurian terrestrial tetrapod from the Triassic period.

SourceUppsala University·JournalScience·DateNov 22, 2018

Unravelling the genetics of fungal fratricide

The study found that the selfish genes were unrelated to each other and use different mechanisms to kill sibling spores, suggesting they may be more common than previously thought. The discovery provides new insights into the genetics of fungal fratricide and has implications for understanding evolutionary patterns.

SourceUppsala University·JournalNature Communications·DateOct 15, 2018

New knowledge about retrovirus-host coevolution

Researchers from Uppsala University have identified previously unknown retroviral insertions in European rabbits, shedding light on how ERVs spread in host populations. The study reveals substantial variation across ERV insertions in different rabbit populations, providing a genomic record of retrovirus-host associations.

SourceUppsala University·JournalProceedings of the National Academy of Sciences·DateOct 8, 2018

Artificial enzymes convert solar energy into hydrogen gas

Artificial enzymes convert solar energy into hydrogen gas using a new method developed by researchers at Uppsala University. The technique utilizes photosynthetic microorganisms with genetically inserted enzymes combined with synthetic compounds, enabling efficient production of renewable hydrogen gas from solar energy.

SourceUppsala University·JournalEnergy & Environmental Science·DateOct 4, 2018

Bravery cells found in the hippocampus

A new study reveals that OLM cells in the hippocampus play a key role in controlling anxiety and risk-taking behavior. The manipulation of these cells can modulate anxiety and may lead to breakthroughs in treating pathological anxiety.

SourceUppsala University·JournalNature Communications·DateSep 7, 2018

How sleep loss may contribute to adverse weight gain

A new study from Uppsala University found that one night of sleep loss can cause tissue-specific changes in gene expression and metabolism, leading to increased fat accumulation and muscle loss. This may explain why shift work and chronic sleep loss increase the risk of obesity and type 2 diabetes.

SourceUppsala University·JournalScience Advances·DateAug 23, 2018

Virus genes from city pond rescue bacteria

Researchers discovered that bacteriophages can transfer genes to E. coli bacteria, enabling them to break down a crucial cell component and reset their metabolism for new survival functions. This study highlights the importance of investigating hidden potential in bacterial cells to understand antibiotic resistance and pathogenicity.

SourceUppsala University·JournalNature Ecology & Evolution·DateMay 28, 2018

Insect toxin detected in the world's longest animal

Researchers at Uppsala University discovered a peptide toxin in the bootlace worm that can paralyze and kill crustaceans and cockroaches, with potential applications in agricultural insecticides. The toxin affects sodium channels, causing electric signalling in nerves and muscles, leading to paralysis.

SourceUppsala University·JournalScientific Reports·DateMar 26, 2018

New method enables high-resolution measurements of magnetism

Researchers from Uppsala University and collaborating institutions developed a new method to measure magnetism at the atomic level, enabling detailed analysis of magnetic nanostructures. This advancement is crucial for the development of next-generation spintronic components that require functional units only a few nanometers large.

SourceUppsala University·JournalNature Materials·DateFeb 6, 2018

Type-2 diabetes: Insulin held up in traffic

A study by Uppsala University researchers reveals that a vesicle attachment defect is the root cause of insulin secretion problems in type-2 diabetes. The defect leads to slowed arrival of new insulin-containing vesicles at the cell membrane, resulting in insufficient insulin release.

SourceUppsala University·JournalCell Metabolism·DateFeb 6, 2018

New technology for accelerated wound healing discovered

The technology involves delivering a human chemokine on site in wounds, increasing immune cell recruitment and specialization to accelerate healing. In preclinical studies, the treatment demonstrated potent effects on acceleration of wound healing in mice and models of diabetes and peripheral ischemia.

SourceUppsala University·JournalProceedings of the National Academy of Sciences·DateFeb 5, 2018