Articles tagged with Research and Development
A cell therapy using myeloid cells bound to drug delivery microparticles reduces disease burden in a preclinical multiple sclerosis model. The therapy partially reverses hind limb paralysis and improves motor functions.
A new PANDA-project aims to develop and test an ear-EEG device that can screen patients for Alzheimer's and Parkinson's diseases. The technology measures brain electrical activity and sleep patterns, with the goal of identifying early signs of the diseases and enabling earlier diagnosis.
Nagoya University researchers have developed a poly(styrenesulfonic acid)-based PEM with an ultrahigh density of sulfonic acid groups, exceeding five times that of typical commercially available membranes. The new membrane exhibits a proton conductivity of 0.93 S/cm at 80°C under 90%RH, six times higher than Nafion or Selemion under th...
Scientists at TUM create genetic reporter proteins that can be resolved by electron microscopy, unveiling invisible cellular structures and processes. The discovery enables further research into disease mechanisms and potential therapeutic cell production.
Researchers at UMass Amherst microbiologists have identified an enzyme involved in TB pathogen's survival and growth. The discovery offers a potential target for drug therapies for the deadly disease, which has few effective treatments and caused over 1.6 million deaths worldwide in 2021.
Researchers developed an AI algorithm that allows electronic devices to express uncertainty when faced with unexpected data, improving cough detection technology. The new approach enables more precise detection with fewer sound samples per second, reducing computing power and addressing privacy concerns.
Scientists at the University of Chicago have created a new material that can bend in half or stretch to twice its original length while still emitting light. The stretchable OLED display has applications in wearable electronics, health sensors, and foldable computer screens.
Researchers developed an AI-based method for virtual staining of histopathological tissue samples, producing images that closely resemble actual chemical-stained samples. This reduces chemical burden and manual work while enabling the use of tissues for other purposes.
Researchers discovered a misfolded alpha-synuclein protein as a potential biomarker for early detection of Parkinson's disease. The test was accurate in detecting the disease 87% of the time and identifying its absence 96% of the time.
Researchers developed a multifunctional patch that detects plant diseases and abiotic stresses like drought or salinity. The patch can detect viral infections up to a week before symptoms appear, enabling growers to take action earlier.
A novel biorefinery process has been developed to minimize the usage of external utilities by reusing by-products from biomass production. The process successfully reduced the total process energy and supplied it by itself, as well as utilizing excess solid by-products for building materials and other purposes.
A study by Cornell University researchers found that using AI in conversations improves communication efficiency and positive emotional language, but participants perceive their partner as less cooperative when suspected of using AI-suggested responses.
The POSTECH team developed a multifunctional tip-enhanced spectroscopy that dynamically controls the physical properties of quasiparticles in 2D materials. This technology increases interlayer excitons' luminous efficiency by 9,000 times and modulates their energy.
A new fluorescent probe, TiY, has been developed to selectively target and kill cancer stem cells, which are responsible for tumor growth. The probe can be used to simultaneously diagnose and treat cancer, offering a promising approach to improving cancer treatment outcomes.
Researchers successfully add purified curcumin to probiotic yogurt, preserving its dissolved form and enhancing its health properties. The study shows that the curcumin inhibits yeast, fungi, and bacteria growth while maintaining the recommended levels of beneficial lactic acid bacteria.
Researchers designed a mechanism for peer-to-peer energy trading in smart grids using a blockchain-based environment and an Arrow-d’Aspremont-Gerard-Varet (AGV) system to ensure security, efficiency, and transparency. The study found that the AGV mechanism is Bayesian incentive-compatible and budget-balanced under weak participation re...
A novel copper-containing polymeric filter can effectively capture carbon dioxide from the air, converting it into sodium bicarbonate that can be released harmlessly into the ocean. The technology has garnered international attention and could be powered by renewable energy in the future.
Researchers at West Virginia University are exploring iodine-based thrusters as an alternative to traditional fuel sources, aiming to reduce dependence on rare noble gases. They plan to develop diagnostic technology to measure the performance of these thrusters, paving the way for widespread use in space exploration.
Researchers discover ZBTB12, a molecular barrier that prevents dedifferentiation in human pluripotent stem cells, and shed light on the core differentiation mechanism.
A team led by Professor Yoshihiro Yamazaki from Kyushu University discovered the chemical innerworkings of a perovskite-based electrolyte developed for solid oxide fuel cells. By combining synchrotron radiation analysis, large-scale simulations, machine learning, and thermogravimetric analysis, they found that protons are introduced at...
Researchers have developed a functional polymeric binder for stable, high-capacity anode material that can increase the current EV range at least 10-fold. The new polymer utilizes hydrogen bonding and Coulombic forces to control volumetric expansion, resulting in a thick high-capacity electrode and maximum energy density.
The new center aims to amplify biomedical research and human health applications, fostering collaboration among innovators. BRIC members will have access to resources and support for applying their nuclear physics expertise in new areas.
Researchers have developed a practical method to generate green hydrogen using natural enzymes, which contain only earth-abundant elements. The new approach enables the efficient production of green hydrogen from sunlight, making it a promising solution for decarbonizing transportation and industries.
A new technique combines machine learning with short-wave infrared fluorescence imaging to detect precise tumor boundaries with higher accuracy than traditional methods. The approach achieved a remarkable per-pixel classification accuracy of 97.5 percent and demonstrated robustness against changes in imaging conditions.
Researchers developed a hybrid micro-robot that can navigate in physiological environments and capture targeted damaged cells. The micro-robot uses electric and magnetic mechanisms to identify and transport single cells for further study.
Researchers at Pohang University of Science & Technology have created a high-performance AI semiconductor device using IGZO, achieving over 98% accuracy in handwritten data classification. The new device's design enables efficient linear and symmetric programming, making it suitable for large-scale AI applications.
Researchers at Texas A&M University have developed the first molecular therapeutic for Angelman syndrome, a devastating neurogenetic disorder. The therapy targets an evolutionarily conserved region in the UBE3A-AS transcript and has shown promising results in clinical trials.
A team of MIT researchers has created an 'unclonable' label system to combat counterfeit seeds in Africa, where fake seeds can cost farmers up to two-thirds of expected crop yields. The system uses biodegradable silk-based tags with unique codes that cannot be replicated.
The CONVINCE project, funded by €4 million, focuses on developing cognitive deliberation capabilities in autonomous robots to enhance safe and robust operation in unstructured environments. The goal is to enable robots to adapt to their surroundings and tasks autonomously without human intervention.
Researchers from POSTECH and University of Ulsan developed an omnidirectionally stretchable pressure sensor mimicking the structure and function of a crocodile's sensory organ. The sensor maintains sensitivity to pressure even when subjected to significant deformation, enabling its use in various wearable devices.
Researchers developed a self-driven lab, AlphaFlow, that uses AI to optimize complex chemical reactions and discover new materials. The system significantly reduces the time needed to develop new chemistries from months to hours.
A recent WHO review reveals a significant shortage of new antibiotics in the pipeline, with only 12 approved drugs introduced between 2017 and 2021. The majority of these drugs target non-critical pathogens, leaving critical ones like Acinetobacter baumannii and Pseudomonas aeruginosa underrepresented.
Researchers at Pusan National University have developed a novel solvent-resistant hole injection layer material, enabling the creation of efficient solution-processed OLED devices. The material exhibits high mobility and excellent film-forming properties, leading to improved efficiency and lifetime compared to existing materials.
A team of researchers, led by UMass Lowell's Neil Shortland, is developing AI systems to help doctors triage patients in emergency situations. The project aims to identify the best human attributes that AI can mirror when making difficult decisions.
A new 'best practice' protocol has been developed by researchers at University of Bath to standardize data collection and reporting in piezoelectric materials. This is crucial to ensure reproducibility in energy harvesting research, which is hampered by inconsistent experimental reports.
The new technique allows for the production of a dozen different soft polymer material morphologies, including ribbons, nanoscale sheets, rods, and branched particles. By precisely controlling three sets of parameters during manufacturing, researchers can fine-tune the morphology of polymeric materials at the micro- and nano-scale.
Researchers at the University of Cincinnati developed an innovative breathing device called PEP Buddy, which improves symptoms of breathlessness, quality of life, and oxygen levels in people with COPD. The study found significant reductions in shortness of breath and improvements in quality of life among participants.
Researchers suggest a four-part framework to identify animal viruses that may infect humans, focusing on viruses from repeat offender families and those with known human compatibility. By studying these viruses early, scientists can develop diagnostic tools and treatments, and be better prepared to combat future pandemics.
Dr. Natasha Kekre, a University of Ottawa associate professor and hematologist, has secured millions in funding and published numerous peer-reviewed papers on CAR-T cellular therapies for cancer treatment. Her work has advanced the immunotherapy field in Canada and made her an expert in cancer immunotherapies.
Alveolus Bio, a UAB startup, has received a $2.5 million FastTrack grant from the NIH to support the development of first-of-its-kind inhaled biotherapeutics for chronic lung disease COPD. The company aims to create FDA-approved treatments for 15.7 million people affected by COPD worldwide.
Researchers developed a hydrogel-based sensor to monitor overactive bladder activity in real-time. The sensor measures both mechanical and bioelectrical activities, allowing for simultaneous monitoring and neural stimulation. This breakthrough has the potential to improve treatment outcomes and minimize side effects.
Research suggests that participants in psychology studies are more likely to exhibit symptoms of personality disorders, which could impact the validity of study results. The prevalence of these disorders may be due to self-selection biases in participant recruitment.
Researchers developed AI models based on UNet and MobileNet architectures to analyze standardized abnormalities in CT images, accurately identifying object presence and confidence. These models achieved an absolute percentage error of less than 5 percent, comparable to human professionals.
A new approach by the Medical University of South Carolina aims to increase clinical trial participation, especially from diverse populations. By making patients eligible for research opportunities by default, while allowing opt-out, the team saw a significant increase in potential participants.
The UTSA ScooterLab will collect data on riders' mobility, context and environment to improve sustainable transportation solutions. The project aims to transform the way we think about micro-mobility.
Researchers developed a technique to predict how quantum systems behave when connected to their environment, turning a problem into a solution. The approach combines techniques from quantum many-body physics and non-Hermitian quantum physics, providing a crucial tool for real-world applications of quantum technology.
Scientists have developed a conductive polymer coating called HOS-PFM that can significantly enhance the performance of lithium-ion batteries in electric vehicles. The coating ensures battery stability and high charge/discharge rates while extending battery life by up to 15 years.
Researchers develop a novel combination therapy using mitoxantrone and vancomycin to treat vancomycin-resistant Enterococcus faecalis (VRE) infections. The therapy stimulates the host immune system, accelerating wound healing and killing bacteria more effectively.
A global team of researchers created an algorithmic tool to identify existing drugs that could be effective against the next pandemic. The PHENotype SIMulator (PHENSIM) uses computer experiments to analyze biomolecules and predict antiviral effects, identifying potential candidates for repurposing.
A recent study found that public investment in critical research contributed significantly to the development of mRNA COVID-19 vaccines. The US government invested at least $337 million in research over 35 years, including basic science and vaccine development.
A new study published in the Journal of the American Heart Association found that participating in home-based cardiac rehabilitation was associated with a 36% lower likelihood of death from heart-related complications among US military veterans within four years. The study analyzed data from 1,120 veterans who enrolled in a 12-week hom...
Children with autism may not process visual illusions in the same way as their peers, indicating a potential issue with predicting and filling in missing visual information. This finding has implications for understanding and supporting individuals on the autism spectrum.
A tiny soft robot has been developed to help doctors perform surgery and search in hard-to-reach places. The robot uses ultraviolet light and magnetic force to climb on any surface, including walls and ceilings, without an external power supply.
Researchers at Texas A&M University have created a new method to monitor flocculation and mixing in real-time, allowing for more precise control over the process. This technique reduces energy consumption by halving the workload and improving precision.
A Berkeley Lab-led team has designed a new type of solid electrolyte consisting of a mix of various metal elements, resulting in a more conductive and less dependent material. The new design could advance solid-state batteries with high energy density and superior safety, potentially overcoming long-standing challenges.
Researchers discovered that frail patients who received additional support before and after surgery were 18% less likely to die within a year. By connecting these patients with medical professionals and resources, they can make healthy lifestyle changes and receive guidance on managing their condition without surgical intervention.
Scientists from NC State University have discovered a way to manipulate the flow of heat through ferroelectric materials by applying different electric fields. The study, published in Advanced Materials, found that varying electric field strengths, types (AC/DC), time, and frequency can alter the thermal properties of these materials.
The CEE team is leading a new project to develop better systems for evaluating the structural health of rail lines and modernizing pavement design and evaluation procedures. Researchers will focus on developing a rail structural capacity rating and Joint Evaluation and Design Integrated (JEDI) Solution software tools.
Scientists have created a non-destructive method to detect and differentiate gibberellins, a class of plant hormones crucial for growth. The new nanosensors can identify changes in GA levels across various plant species, enabling early interventions against salinity stress.
Verkko software assembles gapless human genome sequences quickly and precisely, enabling better assessment of genomic diversity and comparative genomics. This innovation accelerates efforts to generate complete genome sequences of various species, improving research and discovery in the field.