Articles tagged with Allergic Asthma
Researchers found that blocking IL-17A and IL-17F significantly reduces symptoms of severe allergic asthma in mice. The study suggests a new potential treatment for people with this condition, by preventing the production of pro-inflammatory molecules triggered by T-helper cells.
Researchers found that maternal e-cigarette vaping increases the risk and severity of allergic asthma in offspring, with detrimental effects partially mediated through mitochondrial function. The study highlights the need for caution when considering e-cigarettes as a safe alternative to cigarette smoking during pregnancy.
A study by Australian researchers has found that testosterone suppresses the production of immune cells that trigger allergic asthma. The finding may lead to new, targeted treatments for the disease. Women are two times more likely to develop asthma than men after puberty due to testosterone's protective effects.
Researchers found that phthalate exposure during pregnancy and breastfeeding can lead to epigenetic modifications in children, increasing the risk of developing allergic asthma. The study also showed that the effects are not limited to the child, as the offspring of exposed mothers continued to be affected even after birth.
Dasatinib, a cancer treatment, reduces inflammation and improves lung mechanics in mice with allergic asthma. The drug targets tyrosine kinases involved in asthma's signaling pathways.
Researchers at Helmholtz Centre for Environmental Research (UFZ) discovered a protein called syndecan-4 that plays a critical role in developing allergic airway inflammation. The study found that syndecan-4 helps immune cells migrate to T-cells, initiating an immune reaction and sensitization to specific allergens.
Scientists at Mainz University have discovered a new sub-population of regulatory T cells linked to allergic asthma. The Treg cell type plays a decisive role in developing and manifesting the disease, making it a promising early diagnostic indicator.
Researchers have discovered a novel signaling pathway critical to the immune response of cells associated with allergic asthma. Increasing cAMP levels inhibited the cells' inflammatory response, suggesting a potential target for new therapies.
Researchers at McMaster University have successfully tested an antibody that can improve the quality of life for individuals with asthma by relieving inflammation in the lungs. The study found that blocking a specific protein in the lungs with an antibody alleviates baseline inflammation and provides resistance to allergens.
A new study suggests that the enzyme Cbl-b could be a target for drugs used to treat allergic asthma and other autoimmune disorders. Mice lacking Cbl-b exhibited severe allergic asthma symptoms, highlighting its vital role in controlling immune response.
A NIH study found a bacterial protein in common house dust may worsen allergic responses to indoor allergens, leading to asthma. Researchers discovered flagellin boosts allergic reactions in mice with asthma, suggesting cleaning could reduce symptoms by removing bacteria.
UBC researchers found that certain antibiotics alter gut bacteria, increasing severity of asthma in mouse models. Early life is a critical period for establishing a healthy immune system, as the impact of antibiotics on asthma susceptibility disappears in adult mice.
A new anti-asthma medication has been found to nearly eliminate seasonal asthma attacks in children and young adults with allergic asthma. Researchers found that the treatment improved asthma control, reduced symptoms by 25%, and decreased asthma attacks by 30%.
Researchers found that people with allergic asthma are more susceptible to respiratory viruses like the flu due to impaired immune response. Elevated IgE levels in dendritic cells may interfere with antiviral proteins, worsening asthma symptoms.
A study published in PNAS identified TRPA1 as playing a key role in allergic asthma and demonstrated that HC-030031 effectively treated the condition in mice. This breakthrough research could represent a new avenue of treatment for asthma.
Research suggests that a mother's diet during pregnancy can induce epigenetic changes in her offspring, increasing their risk of developing allergic asthma. The study found that high-methyl-donor diets led to more severe airway disease and increased IgE levels in the blood.
Research on farm women reveals an increased risk of allergic asthma associated with pesticide use. The study found a significant increase in asthma prevalence among women who applied or mixed pesticides, with some compounds like parathion linked to nearly tripled risk.