Articles tagged with Atrial Fibrillation
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A study published in the European Heart Journal found that people who work long hours (55+ hours/week) are approximately 40% more likely to develop atrial fibrillation over a ten-year period. The risk is higher among those with pre-existing cardiovascular disease and other risk factors.
Researchers developed a scoring system using electronic medical records to predict patients at high risk for atrial fibrillation after stroke. The system identifies seven risk factors and assigns patients to one of three risk groups, enabling personalized treatment.
A new study found that patients newly diagnosed with atrial fibrillation who received early cardiology care had a 9% lower risk of stroke and an 11% lower risk of death. Early prescription of anticoagulants also appeared to lower the risk of stroke.
Newly diagnosed asymptomatic atrial fibrillation patients have a higher rate of previous stroke compared to those with symptoms. The study found that patients with non-valvular atrial fibrillation have a five-fold increased risk of stroke, and strokes in these patients tend to be severe and disabling.
A study by the University of Birmingham reveals a significant treatment gap for patients with paroxysmal atrial fibrillation, where fewer are prescribed anticoagulants for stroke prevention. This results in preventable strokes, increased risk of death and disability.
A large study found that consuming moderate amounts of chocolate was associated with a significantly lower risk of atrial fibrillation, a common and dangerous type of irregular heartbeat. The study suggested that even small amounts of cocoa consumption can have a positive health impact.
Research published in the journal Heart found that regular chocolate consumption is associated with a lower risk of developing atrial fibrillation. For women, one weekly serving was linked to a 21% lower risk, while for men, two to six weekly servings were associated with a 23% lower risk.
Research found that measures of OSA severity were significant predictors of AF, with oxygen desaturation remaining a significant predictor after adjusting for known risk factors. Women with sleep apnea were more likely to develop AF hospitalizations, highlighting the potential for gender-specific mechanisms.
A study by Intermountain Medical Center Heart Institute found that long-term aspirin therapy does not lower the risk of stroke for patients with atrial fibrillation who are considered low-risk for stroke. Instead, it increases the risk of gastrointestinal and genitourinary bleeding.
A new study has found that delayed treatment with anticoagulation therapy for patients with atrial fibrillation increases the risk of dementia. The study, conducted by researchers at Intermountain Medical Center, included over 76,000 patients and found a significant increase in dementia rates among those who received delayed treatment.
Researchers from the University of Pennsylvania found that CHD patients can safely undergo AF ablation, with similar success rates as those with normal hearts. The multicenter study showed 53% complete success and improved outcomes compared to non-CHD patients.
A new study combines traditional CHA2DS2-VASc risk score with the Intermountain Mortality Risk Score to provide more accurate evaluations of atrial fibrillation patients' individual risks. This allows for better decision-making regarding blood thinners use, taking into account both clinical and biological factors.
Patients with new-onset atrial fibrillation post-TAVR have a nearly five-fold greater risk of early stroke compared to those without AF. The BRAVO-3 trial found that patients with existing or new AF had higher rates of pre-existing comorbidities and were more likely to receive oral anticoagulants.
Researchers have identified a microRNA biomarker that shows a strong association with atrial fibrillation incidence. The study found that low levels of miR 21 are strongly linked to the development of atrial fibrillation, which can increase stroke risk and negatively impact quality of life.
Researchers found combining Intermountain Mortality Risk Score (IMRS) with traditional CHA2DS2-VASc score improves identification of atrial fibrillation patients at higher risk of dementia. This study used data from nearly 75,000 AFib patients with no history of dementia.
A study published in the European Heart Journal found that higher alcohol consumption is associated with an increased risk of developing cardiac arrhythmias. The research, which monitored participants as they drank, found that even moderate drinking can lead to abnormal heart rhythms.
The American Association for Thoracic Surgery has released a new consensus statement on surgical ablation for atrial fibrillation, emphasizing its safety and effectiveness in reducing early death and late stroke risk. The guidelines also recommend hybrid procedures, optimal ablation tools, and standardized training.
Research found that bigger women have a significantly higher risk of atrial fibrillation due to their larger body size, with those in the highest body surface area quartile having nearly three times the risk as those in the lowest. The study's findings suggest that avoiding excess weight may be beneficial for tall individuals.
A new analysis found that apixaban, a non-vitamin K antagonist oral anticoagulant (NOAC), is superior to warfarin in reducing brain bleeds and stroke risk in patients with atrial fibrillation. The study showed that apixaban reduced intracranial hemorrhage by 58% compared to warfarin.
A recent study found that direct acting oral anticoagulants and aspirin may increase heart attack risk compared to vitamin k antagonists like warfarin. Researchers are urging more research on the topic as use of these medications increases.
Researchers at Intermountain Medical Center Heart Institute have identified three microRNA molecules linked to AFib recurrence after ablation therapy. These molecular markers hold promise as screening tools to help determine which patients will benefit from various therapies.
Researchers combined two independent risk measurements to improve stroke and mortality predictions in atrial fibrillation patients. The new tool provides a more accurate scale of low and high risk, helping physicians determine the need for blood thinners in treatment.
Researchers found that patients with persistent AF who are successfully treated with ablation may no longer need blood thinners. In fact, 174 participants discontinued blood thinner use at some point in the three years, and 174 remained off blood thinners at their last follow-up.
A new study suggests that a low dose of apixaban, an oral anticoagulant, can be maintained at safe levels in dialysis patients to potentially prevent strokes. The research indicates that this dosage may be effective for stroke prevention in these patients.
A recent study published in JAMA Network found that nearly 84% of patients with atrial fibrillation who experienced a stroke were not receiving therapeutic anticoagulation prior to their stroke. Therapeutic anticoagulation was associated with lower odds of moderate or severe stroke and lower odds of in-hospital mortality.
A study of over 94,000 patients with atrial fibrillation found that only 16% received recommended anticoagulation therapy prior to stroke. Patients who did receive treatment had less severe stroke outcomes and lower mortality rates. Adherence to guidelines could prevent up to 88,000 strokes per year in the US
A UBC Okanagan study used digital cameras to collect photos from older patients with atrial fibrillation, providing valuable insights into their daily care and environmental context. The images revealed nuances of living with a chronic condition in rural communities.
A systematic review of 14 randomized trials found that vitamin C significantly reduced the incidence of post-operative atrial fibrillation in high-risk patients. The review also showed that vitamin C decreased hospital stay length and intensive care unit stay, with intravenous administration having greater effects.
A new study reveals that catheter ablation significantly reduces symptoms in over half of patients with atrial fibrillation (AF), a condition that increases the risk of stroke and death. The procedure's success rate is higher than expected, but monitoring after treatment is often inadequate.
New clinical practice guidelines recommend surgical ablation for treating atrial fibrillation, showing improved heart rhythm, quality of life, and stroke reduction. Surgical ablation is an effective treatment option for Afib, with significant improvements in long-term outcomes.
Researchers at Nocturnal and GW are developing a new generation of catheters for treating atrial fibrillation with real-time lesion visualization tools. The technology aims to improve treatment options for millions of people affected by the condition.
Patients with atrial fibrillation who use warfarin are two to three times more likely to develop dementia compared to those without atrial fibrillation. Erratic blood levels of warfarin contribute to the risk, suggesting that managing abnormal heart rhythm may also lower dementia risk.
A UK study found that nearly half of stroke patients were not prescribed preventative drugs, including those with high blood pressure and irregular heartbeats. Researchers estimate that up to 12,000 first strokes could be prevented annually through optimal prescribing.
The RE-DUAL PCI study evaluates the safety and efficacy of dabigatran etexilate in AF patients undergoing PCI. This first-ever study to use a dual versus triple antithrombotic regimen with NOAC dosages already approved for stroke prevention will inform optimal anticoagulant choices for AF patients requiring PCI.
Research presented at the American Heart Association's Scientific Sessions 2016 found that disrupted sleep, including insomnia, is independently associated with an increased risk of atrial fibrillation. The study analyzed data from three sources and showed a 26% higher risk for those who frequently woke up during the night.
A new study found that combining rivaroxaban with single or dual anti-platelet therapy reduces clinically significant bleeding in patients with atrial fibrillation who undergo stenting procedures. The treatment strategy also lowers risks of rehospitalization and death from all causes.
A study found that only 46% of hospitalized atrial fibrillation patients receive oral anticoagulants, which can help prevent strokes. Researchers say this highlights a gap in care and emphasizes the need for better optimization of medication decisions during hospital stays and at discharge.
A smartphone application called Cardiio Rhythm uses facial signals to detect subtle beat-to-beat variations in heart rate, correctly identifying over 92% of cases with atrial fibrillation. The technology's convenience makes it attractive for large-scale community screenings.
Researchers found that catheter ablations lower the long-term risk of recurrent stroke by 50% in atrial fibrillation patients with a prior history of stroke. The procedure creates scar tissue to prevent rapid electric currents from causing abnormal heart rhythms.
Researchers found that short episodes of atrial fibrillation are associated with a low risk of stroke and other cardiovascular complications. Patients experiencing only brief episodes of the condition were at no greater risk than those without atrial fibrillation, suggesting that anticoagulants may not be necessary in this group.
A team of researchers found that widely accepted atrial fibrillation risk prediction algorithms do not accurately predict incidence when applied to electronic medical records. The study suggests that existing models may be incompatible with EMR data, leading to inconsistent predictions and potential misdiagnosis.
A smartphone app combined with a hand-held ECG monitor can detect atrial fibrillation with a high degree of accuracy. The condition affects nearly one in 10 people and is associated with a heightened risk of stroke and death.
A new imaging technique can predict who is most at risk for stroke due to atrial fibrillation. The technique, called 'atrial 4D flow CMR,' detects blood flow velocity and can help reduce over-treatment of patients.
A Mayo Clinic study found that NOACs dabigatran, rivaroxaban, and apixaban are at least as effective as warfarin in preventing stroke in atrial fibrillation patients. However, apixaban was associated with lower major bleeding rates, while rivaroxaban had a higher risk of serious bleeding.
The Canadian Cardiovascular Society has released updated guidelines for managing atrial fibrillation, prioritizing the use of non-vitamin K antagonist oral anticoagulants (NOACs) over warfarin. The new recommendations aim to improve patient outcomes and reduce stroke risk.
A large study found that atrial fibrillation is associated with a wide range of serious events, including heart attacks, chronic kidney disease, and sudden cardiac death. The risk of these events is higher than stroke, prompting calls for interventions to reduce non-stroke outcomes.
Atrial fibrillation, a common irregular heartbeat, is linked to genetic variations in genes controlled by Tbx5 and Pitx2. The study offers insights into the mechanisms underlying heart arrhythmias, potentially leading to targeted treatments for patients with AF.
A large-scale clinical trial found that non-vitamin K antagonist oral anticoagulants (NOACs) can be safely used as an alternative to warfarin before cardioversion in atrial fibrillation patients. Edoxaban was shown to be equally effective as current use of warfarin, and expedited the process from initial standard treatment.
The ENSURE-AF trial shows edoxaban as an effective and safe alternative to standard therapy, with comparable rates of stroke and bleeding events. Patients can start edoxaban 2 hours prior to cardioversion if they have access to transoesophageal echocardiography.
The new guidelines aim to improve outcomes in patients with atrial fibrillation by integrating input from different specialties. They recommend oral anticoagulation with NOACs as the first line treatment for eligible patients, and catheter ablation as a first line treatment for selected patients.
A new low-cost application has been developed to detect atrial fibrillation using a smartphone's accelerometer and gyroscope. The algorithm achieved sensitivity and specificity rates of over 95%, making it a promising tool for widespread screening and early detection.
A study found that alcohol-related hospitalization is associated with a doubled risk of ischemic stroke in low-risk patients with non-valvular atrial fibrillation. The study included over 25,000 patients and showed that age and alcohol-related hospitalization were significant predictors of stroke risk.
A study of over 43,000 patients with atrial fibrillation found that new oral anticoagulants (NOACs) provided similar stroke prevention to warfarin, but caused fewer bleeding incidents. NOACs were associated with a lower risk of intracranial bleeding, particularly when compared to warfarin.
A study published in JAMA found that only 34% of patients with stable INR values while taking warfarin remained stable over the subsequent year, indicating that predicting stability is difficult. Non-vitamin K oral anticoagulants may offer improved safety and efficacy but are more costly.
Researchers found an association between atrial fibrillation and smaller frontal lobe brain volumes in a recent study published in Heart Rhythm. The study examined the relationship between AF and brain volume using MRI, revealing that AF was associated with reduced frontal lobe volumes even after adjusting for other factors.
A recent study using a highly sensitive blood coagulation test called dielectric blood coagulometry (DBCM) found that non-Atrial Fibrillation patients with high CHADS2 scores exhibited hypercoagulability. DBCM detected small changes in blood coagulation, particularly in those at higher risk of stroke.
The American College of Cardiology has updated clinical performance and quality measures for treating adult patients with atrial fibrillation or atrial flutter. The new measures include inpatient setting, patient safety, and other domains to improve continuity of care.
A study published in JAMA Cardiology found that blacks with atrial fibrillation have nearly double the risk of adverse outcomes compared to whites. The study analyzed data from the Atherosclerosis Risk in Communities (ARIC) Study and found significant racial differences in outcomes related to AFib.
A study published in JAMA Cardiology found that black individuals with atrial fibrillation have a significantly increased risk of stroke, heart failure, coronary heart disease (CHD), and all-cause mortality compared to white individuals. The rate differences for these outcomes were found to be approximately 1.5- to 2.0-fold greater in ...
Researchers found nearly 40% of AF patients at intermediate to high risk for stroke treated with aspirin alone, despite previous data showing blood thinners more beneficial. The study highlights the need for cardiology specialists to adhere to standardized recommendations regarding the use of oral blood thinners.