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Who is at risk of heart rhythm disorders?

A new international consensus statement outlines the best way to identify people at risk of developing common and devastating heart rhythm disorders, including atrial fibrillation and ventricular tachyarrhythmia. The guidelines focus on accurate risk assessment to enable earlier diagnosis and intervention with lifestyle changes or medi...

SourceEuropean Society of Cardiology·JournalEP Europace·DateJun 15, 2020

Dual therapy reduces risk for bleeding better than triple therapy for patients with atrial fibrillation

A systematic review and meta-analysis found that dual therapy with a direct oral anticoagulant (DOAC) plus P2Y12 inhibitor was associated with reduced risk of major bleeding compared to triple therapy with a vitamin K antagonist (VKA) plus aspirin and P2Y12 inhibitor for patients with nonvalvular atrial fibrillation after percutaneous ...

SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·DateMar 16, 2020

Apixaban may be a safer and more effective than rivaroxaban for preventing stroke and blood clots

A large cohort study published in Annals of Internal Medicine found that apixaban was associated with a lower risk of stroke or systemic blood clots compared to rivaroxaban in patients with nonvalvular atrial fibrillation. The study also showed that apixaban was linked to a lower risk of gastrointestinal bleeding or bleeding in the brain.

SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·DateMar 9, 2020

Ohio State first in US to use new atrial fibrillation device

The Ohio State University Wexner Medical Center has successfully used a new atrial fibrillation device, achieving 100% pulmonary vein isolation without nerve injuries or serious side effects. The PFA technology uses pulsed electric fields to interrupt pathways and triggers in the heart, potentially becoming the standard tool for resolv...

Zebrafish teach researchers more about atrial fibrillation

Researchers have found a possible link between a genetic variation and atrial fibrillation in zebrafish, suggesting a structural defect in the heart muscle and mitochondria. Early treatment with antioxidants may prevent the disorder in fish, but more research is needed to understand its human implications.

SourceUniversity of Copenhagen - The Faculty of Health and Medical Sciences·JournalProceedings of the National Academy of Sciences·DateJan 21, 2020

Brush your teeth to protect the heart

A nationwide cohort study in Korea found that frequent tooth brushing reduced the risk of atrial fibrillation and heart failure by 10% and 12%, respectively. The study suggests a potential mechanism: reducing bacteria in the subgingival biofilm, which can prevent translocation to the bloodstream.

SourceEuropean Society of Cardiology·JournalEuropean Journal of Preventive Cardiology·DateDec 2, 2019

Research improves understanding of mechanism of atrial fibrillation

Researchers at Baylor College of Medicine have discovered a functional link between noncoding DNA regions called Pitx2 enhancers and the expression of the Pitx2 gene in relation to atrial fibrillation. This interaction prevents predisposition to the condition by looping and folding distant Pitx2 enhancers to make contact with the gene.

SourceBaylor College of Medicine·JournalProceedings of the National Academy of Sciences·DateOct 21, 2019

Electrical-first cardioversion strategy for AFib results in shorter ED length of stay

A multicenter randomized controlled trial confirms an electrical-first approach is more effective in restoring sinus rhythm and shortening ED length of stay. The study found that patients managed with this strategy were discharged within four hours at a higher rate than those receiving a chemical-first approach.

SourceSociety for Academic Emergency Medicine·JournalAcademic Emergency Medicine·DateSep 11, 2019

What's at the 'heart' of a heartbeat?

Atrial fibrillation is a major concern due to its association with serious complications like heart failure and stroke. Researchers have identified a new piece of the puzzle that has changed the field's understanding of the molecular mechanisms leading to atrial fibrillation, involving a phosphatase regulatory subunit known as PPP1R3A.

SourceBaylor College of Medicine·JournalCirculation·DateAug 20, 2019

Beta blockers can block the effects of stress and anger in patients prone to emotion-triggered atrial fibrillation

A new study found that beta blockers can reduce the triggering effect of anger and stress on atrial fibrillation in patients prone to emotion-triggered AF. Patients taking beta blockers experienced fewer AF episodes, with a reduced pro-arrhythmic effect of anger or stress compared to those not taking these medications.

SourceElsevier·JournalHeartRhythm Case Reports·DateJun 4, 2019

New research addresses incidence of atrial fibrillation after aortic valve replacement

Researchers found that approximately 50 percent of hospitalizations for both TAVI and surgical aortic valve replacement were associated with the development of new atrial fibrillation. Hospitalizations with new atrial fibrillation had higher odds of in-hospital stroke and in-hospital death compared to those without, highlighting the ne...

SourceUniversity of Alabama at Birmingham·JournalJAMA Internal Medicine·DateJun 3, 2019

Higher hospital readmission rates for cardiac patients in Northern vs. Southern Ontario: Importance

A study published in the Canadian Journal of Cardiology found that patients in Northern Ontario had higher hospital readmission rates for heart conditions, despite similar survival rates at 30 days. The researchers suggest providing timely transitional care and improving access to specialist care as key strategies to reduce readmissions.

SourceElsevier·JournalCanadian Journal of Cardiology·DateFeb 28, 2019

Should we screen people for irregular heartbeat?

Screening for irregular heartbeat has been proposed as a potential solution to reduce stroke risk, but experts disagree on its effectiveness. Mark Lown suggests that trained clinicians can accurately identify positive cases, while Patrick Moran raises concerns about the lack of evidence on screening's benefits.

SourceBMJ Group·JournalThe BMJ·DateFeb 13, 2019

Do women with breast cancer have a higher risk of atrial fibrillation?

A new study published in HeartRhythm found that women with breast cancer have an increased risk of developing atrial fibrillation within three years following their cancer diagnosis compared to other women of the same age. The risk is higher for younger patients, with more than doubled incidence in those under sixty years old.

SourceElsevier·JournalHeartRhythm Case Reports·DateJan 29, 2019