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Researchers hope to integrate social determinants of health and eradicate inequities in atrial fibrillation diagnosis, management and outcomes

Atrial fibrillation diagnosis and management are often hindered by social determinants of health, which can lead to adverse outcomes. Researchers hope to address this issue by integrating SDOH into AF research, enabling more equitable access to care and management decisions.

SourceBoston University School of Medicine·JournalJAMA Cardiology·TypeData/statistical analysis·DateDec 7, 2022

Screening for stroke risk can save lives and money

Research conducted at Linköping University found that screening for atrial fibrillation in older people could increase the chance of preventing stroke while saving money for healthcare systems. The study, based on data from the STROKESTOP clinical trial, suggests that screening can be a cost-effective intervention.

SourceLinköping University·JournalEuropean Heart Journal·DateNov 9, 2022

Severe obesity in youth a risk factor for early atrial fibrillation

A University of Gothenburg study found that severe obesity at age 18 is associated with a three- to fourfold increased risk of developing atrial fibrillation in younger middle age. The study analyzed data from over 1.7 million men in Sweden and found that higher BMI was linked to mortality risk, heart failure, and ischemic stroke.

SourceUniversity of Gothenburg·JournalJournal of the American Heart Association·TypeData/statistical analysis·DateNov 9, 2022

National study suggests it’s time to rethink how we treat atrial fibrillation

A national study published in The New England Journal of Medicine finds that early intervention with catheter cryoablation can halt disease progression and reduce serious health risks. Cryoablation is more effective than antiarrhythmic drugs in reducing the risk of persistent AF, hospitalization, and adverse events.

SourceUniversity of British Columbia·JournalNew England Journal of Medicine·TypeRandomized controlled/clinical trial·DateNov 7, 2022

1.3 million American adults with diabetes ration their insulin due to cost; younger adults and the uninsured are most likely to ration

A study found that 16.5% of American adults with diabetes ration their insulin, with younger adults and the uninsured being most affected. Insulin rationing is often linked to cost concerns, with many patients delaying purchases or taking less insulin than needed.

SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·TypeObservational study·DateOct 17, 2022

Are smartwatch health apps to detect atrial fibrillation smart enough?

A study published in the Canadian Journal of Cardiology found that smartwatch health apps detecting atrial fibrillation generated a high rate of false positives and inconclusive results, especially in patients with certain cardiac conditions. Better algorithms and machine learning may help improve the accuracy of these devices.

SourceElsevier·JournalCanadian Journal of Cardiology·TypeExperimental study·DateOct 12, 2022

Cleveland Clinic researchers identify diabetes drug metformin as potential atrial fibrillation treatment in collaborative research

Researchers found that metformin targeted 30 genes associated with atrial fibrillation, showing direct effects on gene expression for eight. The study suggests metformin may be a promising candidate for treating atrial fibrillation due to its potential to reduce the risk of complications such as stroke and heart failure.

SourceCleveland Clinic·JournalCell Reports Medicine·DateOct 11, 2022

New risk score predicts mortality for atrial fibrillation patients undergoing transcatheter aortic valve replacement

A new risk score can help predict mortality for patients with atrial fibrillation who have undergone successful TAVR and been discharged home. The risk score was developed using data from the ENVISAGE-TAVI AF trial, which found that patients with certain clinical risks were more likely to die within a year of discharge.

Johns Hopkins researchers find link between dementia and atrial cardiopathy

Researchers found a link between atrial cardiopathy and dementia in older adults, with those having the condition at a higher risk of developing dementia over time. The study suggests that subtle changes in the left atrium may be an independent risk factor for dementia, even after controlling for other vascular risk factors.

SourceJohns Hopkins Medicine·JournalJournal of the American Heart Association·DateAug 10, 2022

Efforts to save money on prescription drugs associated with increased stroke risk for seniors

A new study by the University of Southern California found that formulary restrictions and prior authorization policies can limit access to life-saving medications like NOACs, leading to increased stroke risk. The research suggests that these policies may be 'penny wise and pound foolish' for patients with atrial fibrillation.

SourceUniversity of Southern California·JournalThe American Journal of Managed Care·TypeData/statistical analysis·DateAug 8, 2022

Wrist-worn devices are shown by mass general researchers to be cost-effective for screening of atrial fibrillation

Researchers from Massachusetts General Hospital found that wrist-worn devices are more cost-effective than traditional electrocardiograms and pulse palpation for screening individuals with atrial fibrillation. The use of these devices was also associated with a reduction in stroke incidence.

SourceMassachusetts General Hospital·JournalJAMA Health Forum·TypeComputational simulation/modeling·DateAug 5, 2022

ACP offers guidance on the ethical use of genetic testing and precision medicine

The American College of Physicians (ACP) has issued a position paper on the ethical use of genetic testing and precision medicine in internal medicine. The guidelines address key issues such as incidental findings, education for physicians and patients, and counseling needs. ACP emphasizes the need for ongoing surveillance and anticoag...

SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·TypeLiterature review·DateJul 25, 2022

Atrial fibrillation after surgery is linked to an increased risk of hospitalization for heart failure

A study of over three million patients found that post-operative atrial fibrillation increases the risk of hospitalization for heart failure. The risk is present regardless of whether surgery was performed for a heart condition, and can be as high as doubling in non-heart-related conditions.

SourceEuropean Society of Cardiology·JournalEuropean Heart Journal·TypeObservational study·DateJun 28, 2022

NOACs associated with lower risk for diabetic complications and mortality compared with warfarin

A retrospective cohort study of patients with atrial fibrillation and diabetes found that non-vitamin K antagonist oral anticoagulants (NOAC) were associated with a lower risk of diabetes complications and mortality than warfarin. The study suggests that NOAC may be a better therapeutic choice for this patient population.

SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·TypeData/statistical analysis·DateFeb 14, 2022

USPSTF statement on screening for atrial fibrillation

The USPSTF recommends against screening for atrial fibrillation in asymptomatic adults aged 50 or older. The current evidence is insufficient to assess the balance of benefits and harms of screening, which is associated with a substantial increase in stroke risk. Atrial fibrillation is a major risk factor for ischemic stroke.

SourceJAMA Network·JournalJAMA·DateJan 25, 2022

Safer, newer blood thinners are under-prescribed for elderly and at-risk patients

A new study published in the Canadian Journal of Cardiology found that frail patients with atrial fibrillation are under-prescribed for direct oral anticoagulants (DOACs), a safer alternative to traditional warfarin treatment. Despite needing DOACs most, these patients are less likely to receive them than non-frail patients.

SourceElsevier·JournalCanadian Journal of Cardiology·TypeData/statistical analysis·DateDec 20, 2021

Simple surgical technique associated with significant reduction in the risk of atrial fibrillation after cardiac surgery

A new study found that a simple surgical technique called posterior left pericardiotomy significantly reduces the risk of atrial fibrillation in patients undergoing cardiac surgery. The procedure, which involves draining excess fluid and small clots from the heart sac, was associated with a 56% lower incidence of irregular heart rhythm...

SourceWeill Cornell Medicine·JournalThe Lancet·DateNov 15, 2021

Artificial intelligence–based method predicts risk of atrial fibrillation

Researchers at Massachusetts General Hospital developed an AI-based method to predict atrial fibrillation risk based on electrocardiogram data. The method was highly predictive, especially in subsets of individuals with prior heart failure or stroke, and could serve as a pre-screening tool for patients at risk.

SourceMassachusetts General Hospital·JournalCirculation·TypeComputational simulation/modeling·DateNov 15, 2021