Articles tagged with Brain Injuries
Researchers have identified nine distinct groups of microglia, including some that appear only in embryonic or newborn stages, and others that are involved in myelination. These findings may help uncover new roles for microglia in disease and development, and could lead to the development of therapies targeting specific subpopulations.
A study by Washington State University found that rural children with mild traumatic brain injuries receive less care and have significantly higher healthcare costs compared to urban youth. This disparity is attributed to limited access to specialized services and a shortage of healthcare providers in rural areas, leading to longer tra...
Researchers at Virginia Tech are leading a national concussion study to examine the impact of gender on injury response, exploring how men's and women's rugby and lacrosse athletes respond differently to head injuries. The $1M grant will support data collection using advanced sensors and imaging techniques.
A new Veterans Affairs study found that Iraq and Afghanistan veterans with a history of repeated traumatic brain injuries are at much greater risk for recent suicidal ideation compared to those with one TBI or none. The researchers identified poor sleep quality and depression as key risk factors for suicidal thinking.
Researchers have found that electroencephalography (EEG) can identify patients who are cognitively aware but unable to respond due to severe brain injury. The study suggests that EEG may be used as a cost-effective screening tool to help stratify patients and identify those with high levels of cognitive function.
A UCLA cell study has discovered the impact of head injuries on individual cells and genes, leading to serious brain disorders. The researchers found that hundreds of genes are adversely affected by mild traumatic brain injury, which can later lead to diseases such as Alzheimer's and Parkinson's.
A UCSF-led research consortium will investigate the causes and effects of traumatic brain injury (TBI) using a $3.45 million grant from the NFL's Play Smart. Play Safe initiative. The study aims to track patients over several years to advance understanding of TBI.
A systematic review and meta-analysis of 17 studies involving over 700,000 patients with concussions or mild traumatic brain injury found a significant association between the two conditions and an increased risk of suicide. However, the absolute risk was small due to the low mortality rate among these patients.
The American Academy of Pediatrics recommends light physical activity and allows electronic device use during concussion recovery. Young athletes should stop playing immediately after a suspected concussion but can engage in brisk walking and academic workloads with reduced intensity.
A new study found that patients with atrial fibrillation show signs of asymptomatic brain injury. Three biomarkers were significantly higher in AF patients, suggesting chronic cerebral injuries may contribute to neurodegenerative problems.
Researchers found microscopic neuropathology and neurophysiological changes in a rat model of mild traumatic brain injury. The study suggests that even mild exposure to a single blast shock wave can induce pathogenic effects that accumulate over time.
A new study examines geographic disparities in death due to traumatic brain injury among US veterans, finding higher mortality rates for those living in the US territories. The researchers highlight concerns about potential differences in healthcare quality between the US mainland and US territories.
The Traumatic Brain Injury Model Systems Center (TBIMSC) program has served as a critical source of research to improve care and outcomes for patients with TBI. The TBIMSCs have produced hundreds of research papers advancing the field, including studies on long-term health, social participation, employment, and quality of life.
A study in mice found that eliminating microglia cells eliminated inflammation following traumatic brain injury, offering a potential target for treatment. The research aims to understand cellular-level changes associated with sports-related concussion and other brain injuries.
UTA researcher Weidong Zhou is developing a bioresorbable sensing platform for brain implants that can be absorbed by the body, eliminating the need for surgeries. This device will increase patient comfort during recovery and reduce complications from monitoring devices.
Researchers at Virginia Tech are conducting a three-year study to identify the root causes of epilepsy development after traumatic brain injuries. The team aims to find predictive biomarkers and strategies to prevent brain changes that lead to epilepsy.
Researchers have developed a mouse model expressing human tau protein to study the effects of repetitive brain injury on cognitive function, motor dysfunction and white matter damage. The study found that repetitive concussive injuries resulted in chronic disruptions in white matter and associated neuroinflammation.
Children whose parents are injured may experience altered sleep habits due to post-traumatic stress disorder from military combat. Researchers found a 48% increase in sleep visits among these children, with some experiencing increased symptoms of insomnia and restlessness.
Research at the 2018 American Academy of Pediatrics National Conference found that traumatic brain injury (TBI) in children can lead to increased risk of developing neuropsychiatric disorders such as headache, depression, and mental or intellectual disorders. The study analyzed data from over 1260 children with TBI and found that 39% d...
Researchers found elevated levels of microRNA biomarkers indicating concussions before the season started in college football players. Cognitive tests showed those with balance and memory issues had higher biomarker levels, suggesting past head injuries persisting over time.
New research published by the Journal of the Royal Society of Medicine highlights the high burden of sport-related injuries among children and adolescents. The study found that almost half of sport injury-related emergency department attendances involved children under the age of 19, with fractures being the most common type of injury.
Researchers aim to develop more efficient classification and predictive models for traumatic brain injuries, which would allow clinicians to provide targeted care and improve patient outcomes. The study's findings could also inform clinical trials and allocate resources more effectively.
A landmark study published in JAMA found that brain cooling, a long-debated treatment for traumatic brain injury (TBI), offers no benefits to patients. The POLAR trial involved 511 patients across six countries and showed that neither group had significantly better outcomes in terms of living independently after TBI recovery.
A new study found that athletes with a specific gene variant associated with dyslexia were less likely to suffer concussion injuries. The study suggests that the more diffuse wiring of the dyslexic brain may provide neuroprotection against impact injuries.
Researchers used a novel method to analyze individual brain cells in mice, revealing specific genes that may play roles in traumatic brain injury. Treatments targeting these genes, such as thyroid hormone therapy, showed promise in improving learning and memory tasks.
A new study published in JAMA found that moving the kickoff line to reduce speed and collisions on kickoffs resulted in a significant decrease in concussion rates. The study, conducted by the Ivy League and University of Pennsylvania School of Medicine, showed a 68% reduction in concussions after implementing the rule change.
Researchers analyzed data from the TBI Model System National Data and Statistical Center to identify physical, cognitive, and psychosocial characteristics associated with mortality in chronic TBI survivors. Independence in mobility and community participation were found to be important factors for long-term survival in this population.
Researchers found a new mechanism involving KCNB1 potassium channels that builds up toxins in brains affected by Alzheimer's disease. The build-up is caused by oxidation and can also contribute to other conditions such as traumatic brain injury.
Researchers found a correlation between neurobehavioral symptoms and unemployment among individuals with moderate-to-severe TBI. Frontal system neurobehavioral syndromes can predict employment outcomes, highlighting the need for rehabilitative strategies to address these behaviors.
Researchers developed a new MRI technique that analyzes overlooked data to reveal brain cell density and connectivity. This may aid in diagnosing brain conditions such as Alzheimer's disease, multiple sclerosis, traumatic brain injury, and autism.
The study analyzed national survey data to estimate lifetime TBI in children and found that such injuries send children to emergency departments and carry risk for long-term adverse outcomes. Parents reported diagnoses, which may lead to underestimation of TBI prevalence.
A visual aid designed for parents of children with minor head injuries helped them communicate with emergency medicine physicians and make informed decisions about their child's care. Parents who used the decision aid had better understanding of symptoms, relative risk of brain injury, and pros and cons of CT scans.
A study found that infant walker-related injuries decreased dramatically between 1990 and 2014, largely due to improved safety standards. The number of injuries dropped by 90% during the study period, with falls down stairs being the leading cause.
Researchers found that re-engaging the brain immediately after injury can help recover from brain damage or stroke faster. The study suggests that other primitive brain regions may be involved in touch perception and that patients could benefit from earlier reintroduction to activities.
Mice deficient in tPA exhibited greater white matter damage and cognitive function loss after TBI, while tPA treatment improved neurological function. The study suggests a potential therapeutic target for recovering from TBI.
The new guidelines focus on the needs of clinicians and managers providing rehabilitation care for patients with moderate to severe TBI. The guidelines cover topics such as intensity and frequency of services, managing behavioral disorders, and social participation.
The new guidelines standardize a framework for recognizing, treating and managing a child's recovery from mild traumatic brain injury. Key recommendations include screening for risk factors, safe prescribing and education for children and families.
The CDC has published a comprehensive guideline for the diagnosis and management of pediatric mTBI, which covers diagnosis, prognosis, management and treatment for all causes of pediatric mTBI. The guideline includes 19 sets of recommendations for healthcare professionals to take to improve health outcomes.
A new CDC treatment guideline for children with concussions provides guidance on diagnosis, management, and follow-up care. The guideline recommends validated symptom scales for diagnosis and assessing risk factors for prolonged recovery.
The CDC guideline provides 19 recommendations for diagnosing, managing, and treating mild traumatic brain injury in children, including return to school and symptom management. The guideline aims to improve clinical decision-making and treatment outcomes for pediatric concussions.
Dr. Lequerica's work focuses on the relationships between insomnia and fatigue after TBI, aiming to generate effective interventions to address the needs of TBI survivors. He has authored over 40 peer-reviewed publications and is a leading expert in brain injury rehabilitation.
Researchers at University of Georgia have successfully reproduced the effects of traumatic brain injury and stimulated recovery in neuron cells grown in a petri dish. The procedure has significant implications for studying and treating such injuries.
Researchers at Stanford University found that head positioning is a more important factor in determining concussion risk than neck tension. Small variations in position can affect the subsequent rotation of the head and increase or decrease concussion risk.
Researchers found a lower retention rate among Hispanics (85.2%) compared to blacks (90.5%) and whites (98.5%) in TBI outcomes research. Environmental and socio-economic factors with race/ethnicity interactions are crucial to consider for effective retention strategies.
A Danish national register study found a higher risk of suicide among those with traumatic brain injury (TBI) compared to the general population. The risk was particularly high among those with severe TBI, multiple medical contacts, and longer hospital stays.
Researchers found that children with a history of mild traumatic brain injury do not have an increased genetic risk for attention-deficit/hyperactivity disorder (ADHD), contrasting with developmental ADHD. The study suggests at least two forms of ADHD, one linked to inherited genes and the other to traumatic brain injury.
A study found that foreign-born Hispanics living in areas with many foreign language speakers were 2.8 times more likely to engage in productive activities like employment and volunteer work one year after TBI. The researchers emphasize the importance of tailoring interventions to individual needs, considering neighborhood factors.
A new guideline provides recommendations for improving diagnosis, health outcomes, and care of people with prolonged disorders of consciousness. The guideline emphasizes the importance of early and accurate diagnosis to avoid misdiagnosis and premature treatment withdrawal.
A three-part study of 22 retired pro football and hockey players found no increase in the rate of early-onset dementia or cognitive decline. Standard neuropsychological tests and brain imaging scans showed minimal differences between groups, contradicting previous concerns about CTE.
Researchers at Vanderbilt University have identified a key enzyme that drives neuron death in neurodegenerative diseases, including Alzheimer's and ALS. The enzyme histone deacetylase 1 (HDAC1) modifies a molecular motor that triggers signaling agents to travel down the axon, killing the neuron.
A new study by researchers at Albert Einstein College of Medicine found that women's brains are five times more extensive in damaged tissue after repeated soccer heading compared to male players. The study suggests sex-specific guidelines may be necessary for preventing soccer-related head injuries.
Researchers at the University of Guelph have discovered that leopard geckos can create new brain cells using a specific type of stem cell. This finding has implications for treating brain injuries and diseases, as it suggests that geckos may be able to regenerate parts of their brains.
A Rutgers-led team of scientists has identified two molecules that protect nerve cells after traumatic brain injury and could lead to new treatments. The study found that speeding the breakdown of guanine protects neurons from injury and retains brain functioning.
A new diagnostic blood test developed by Banyan Biomarkers Inc. has been validated to correctly identify 99.6% of patients without traumatic brain injury (TBI) on head CT scans. The test reduces unnecessary head CT scans, radiation exposure and healthcare costs associated with TBI treatment.
A new blood test, Banyan Brain Trauma Indicator, has been approved to help diagnose traumatic brain injuries. The test detects two brain proteins in the blood after a head injury and can predict the presence of an intracranial injury on a head CT scan.
A blood test has been shown to accurately identify patients without traumatic intracranial injuries, reducing the need for CT scans. The test uses biomarker proteins released into the bloodstream after a brain injury and showed a high sensitivity rate of 99.6%.
Recurrent injury rates were six times higher in girls' soccer and nearly three times higher in girls' basketball without athletic trainers. Schools with athletic trainers better identified athletes with concussion and applied evidence-based injury prevention strategies.
Researchers found that lysophosphatidic acid levels increase after traumatic brain injury, particularly in areas associated with cell death and axonal injury. Elevated LPA may serve as a biomarker for TBI through blood testing, providing a prognostic indicator of injury and outcome.
A pre-clinical pilot study found that a combination therapy of CBD and an NMDA antagonist improved cognitive functions and showed no adverse effects in animals. Researchers believe this treatment could reduce symptoms associated with concussion, traumatic brain injury, and post-injury brain cell inflammation.
A recent study published in the Journal of Head Trauma Rehabilitation found that obesity and overweight are associated with chronic disease risks for survivors of moderate to severe traumatic brain injury. The study included 7,287 adults with TBI who underwent inpatient acute rehabilitation.