Articles tagged with Brain Injuries
Researchers found elevated levels of tau and ubiquitin C-terminal hydrolase L1 biomarkers after high-acceleration head impacts, even without clinical concussion. The study suggests a potential new avenue for reducing risk to young athletes through technological improvements and game rule refinements.
Researchers will investigate the role of sphingolipids in forming microparticles associated with increased risk of blood clotting after traumatic brain injury. The goal is to develop therapies to prevent and treat post-injury blood clots.
A new study found that over 2.2 million children aged 5-17 were treated for bicycle-related injuries in US emergency departments between 2006 and 2015. Helmet use was associated with lower head and neck injury rates, but laws enforcement varies by state.
Microglia, specialized immune cells in the brain, have been found to gobble up the remnants of injured neurons, preventing damage from spreading to neighboring neurons. This discovery could lead to new strategies for boosting microglial clearance and limiting neurodegeneration after brain or spinal cord injury.
Developmental prosopagnosia often occurs due to a neurobiological problem in the brain affecting visual recognition broadly. The study found that DPs had reduced responses to faces but normal responses to objects, scenes, and bodies across all face-selective areas.
A new study reveals that N-acetylaspartate (NAA) molecules can inhibit the clumping of amyloid-beta proteins, which are associated with cognitive decline and neurological problems. By restoring NAA levels after head trauma or in neurological diseases, it may be possible to block the progression of amyloid pathologies.
A pilot study found that a simple problem-solving task activated the region responsible for memory function in athletes with concussions, potentially improving symptoms of depression and anxiety. The research challenges current guidelines recommending total inactivity after a brain injury.
Researchers analyze RFK's injuries from 1968 assassination, noting similarities between then and now in gunshot wound care. They conclude that while aggressive treatment was made to save Kennedy, his severe brain injury would likely be fatal with modern techniques.
A new study confirms helmets are effective in protecting skiers and snowboarders from some head injuries, but found no significant reduction in the risk of traumatic brain injury (TBI) or concussion. Helmet use was associated with a lower risk of non-head injuries, suggesting that helmet users take less risk.
Researchers found no significant link between fluid infusion and brain injury in children with DKA, contrary to decades of clinical practice. The study provides more treatment flexibility for clinicians, but the authors continue to investigate potential causes of neurological damage.
A new study found that military service members who depicted psychological injuries in their artwork had more acute post-traumatic stress disorder symptoms than those who used symbols of their military units. The research team linked themes in masks made by active service members to measures of depression, anxiety, and PTSD.
Researchers have found evidence that dissolving NETs can reduce swelling and improve blood flow after traumatic brain injuries. A drug called DNase, which is currently used to thin out lung mucus in cystic fibrosis, appears to dissolve NETs and has shown promise in reducing swelling and improving recovery.
Researchers have identified a safer way to make rugby tackles by reducing the impact on the head. The recommended techniques include tackling at the lower trunk and avoiding high-impact tackles to the upper trunk. These strategies aim to minimize the risk of concussions and other head injuries.
Researchers found cognitive training reduced depressive symptoms and improved brain health in individuals with chronic traumatic brain injury. The study showed significant reductions in depressive symptoms, increased cortical thickness, and improved neural network connectivity.
A new study published in JAMA Network Open found that nearly half of concussion patients receive no follow-up care within three months of discharge from the hospital. The researchers used data from over 2,700 brain injury patients and found a significant gap in care for patients with lesions on their head CT scans.
A new study found that many patients with traumatic brain injuries (TBI) and concussions do not receive adequate follow-up care after hospital discharge. The study revealed that approximately half of the patients saw a general practitioner, while about half were discharged without TBI educational materials.
A nationwide study found that over half of concussion patients are lost in the healthcare system shortly after diagnosis, posing a significant risk to their health. The lack of follow-up care is particularly concerning, as it can lead to debilitating symptoms and prolonged recovery times.
Researchers found that many patients with mild traumatic brain injury (TBI) do not receive educational materials or see clinicians for follow-up care after emergency department discharge. Persistent symptoms can impact their daily lives and require additional medical attention.
A new model reveals that brain cooling can reduce pressure inside the head, relieving swelling and further injury. Cooling newborn babies' scalps to 10C could help their core brain temperature fall, aiding recovery from birth complications.
The VTC Research Institute is developing a test to diagnose mild traumatic brain injury (mTBI), which can have long-term damage despite subtle or no physical signs. The test combines analysis of multiple biomarkers with imaging and cognitive tests.
Children with brain injuries face significant challenges transitioning to school, including educator lack of understanding and catching up on missed work. Leading researchers highlight the need for effective supports to improve academic achievement and reduce economic and social disadvantage.
Researchers tracked over 350,000 veterans and found a significant link between concussion and dementia, with concussion alone doubling the risk. The study suggests that traumatic brain injury may hasten neurodegenerative conditions by inducing or accelerating abnormal protein accumulation.
Researchers discovered changes in tiny blood vessels linked to cognitive symptoms in patients with traumatic brain injuries (TBIs). The study may lead to tailored therapies by pinpointing specific types of TBIs.
Research at Albert Einstein College of Medicine found that frequent soccer ball heading is associated with poorer performance on psychomotor speed and attention tasks. Players who headed the ball more frequently showed subtle reductions in neuropsychological function, which may lead to microstructural changes in the brain.
Researchers at UTHealth will investigate a stem cell therapy using MultiStem in severely injured trauma patients to prevent post-injury organ failure and improve recovery rates. The Phase 2 clinical trial aims to enroll approximately 150 patients and is subject to FDA review and approval.
Researchers found specific small molecules in blood plasma accurately predict whether someone has sustained a mild traumatic brain injury (mTBI) or not. The discovery could lead to reliable diagnostics for concussions.
A new study reveals significant differences in post-concussion symptom severity and length of recovery between male and female college athletes. Notably, female athletes who used hormonal contraceptives experienced different outcomes compared to non-users, suggesting a potential impact on concussion recovery.
Researchers at UCSF found a 56% increased risk of Parkinson's disease among veterans with concussion compared to those without traumatic brain injury. The study followed over 300,000 veterans for an average of 4.6 years and adjusted for age, sex, and other health conditions.
A large population of U.S. veterans with mild, moderate, or severe traumatic brain injury were found to have a higher risk of developing Parkinson's disease. Those with mild traumatic brain injury had a 56% increased risk, while those with moderate to severe injuries had an 83% and 71% increased risk respectively.
In a breakthrough study, NIH scientists identified distinct immune cell subsets that work together to repair the damaged meninges and blood vessels in mice. The research provides new insights into the recovery process after concussion and may lead to the development of targeted therapies to improve patient outcomes.
A Portland State University research team published an interactive diagram and web-based presentation in Frontiers in Neurology, revealing the complex nature of mild traumatic brain injury (TBI). The causal-loop diagram shows how specific variables interact to influence concussion recovery.
The new Glasgow Coma Scale-Pupils score (GCS-P) tool combines GCS scores and pupil reactivity to provide a more comprehensive assessment of traumatic brain injury (TBI) severity and prognosis. The GCS-P has been validated to be as predictive as other, more complex models, while being easy to apply and communicate.
A nationwide study of 2.8 million people over 36 years found that sustaining a traumatic brain injury (TBI) is associated with an increased risk of developing both dementia and Alzheimer's disease. The risk of dementia increased with the number and severity of injuries, even a single mild TBI.
A Norwegian study reveals that even mild concussions can lead to long-term headache woes, affecting twice as many people as the general population. The research highlights the need for closer follow-up of patients with head injuries who experience persistent headaches.
A large study found a significant link between traumatic brain injury (TBI) and dementia, with the risk increasing by 24% in individuals with TBI history. The study also found that the severity and number of TBIs were associated with increased dementia risk.
A new scoring system, GCS-Pupil, improves the assessment of brain injuries by adding a simple score for pupil response. This allows doctors to quickly predict patient conditions and make informed decisions about care.
A recent Ohio University study found that 67 percent of theater workers have experienced concussion-related symptoms and head impacts; 77 percent had more than three head impacts. Many respondents continued working despite experiencing symptoms, citing concerns about not wanting to be seen as 'not tough enough',
Researchers found that concussions occur when a deep area of the brain shakes rapidly and intensely, straining surrounding tissues. The study's findings suggest a complex relationship between head impacts and brain motion, highlighting the need for further research to improve diagnosis, treatment, and prevention of concussions.
A study by Mehmet Kurt from Stevens Institute of Technology found that concussions occur when deep white matter regions of the brain, particularly the corpus callosum, shake more rapidly and intensely than surrounding areas. This understanding could lead to better helmet designs and real-time diagnostic tools for athletes.
Theresa Currier Thomas has received a $1.65 million grant to study traumatic brain injury and develop more effective treatments. The research aims to understand how communication in the brain changes after an injury, with implications for cognition, sensory processing, and mental health.
A Carnegie Mellon University team has received a three-year grant to refine a custom EEG system that can identify early markers for worsening brain injuries. The team will use the high-density EEG to detect cortical spreading depolarizations, or brain tsunamis, which are biomarkers for worsening brain injuries.
Researchers at the University of Nottingham are developing a new neonatal transport system to reduce vibration and stress on premature babies. The system aims to improve neurological outcomes and long-term quality of life for these vulnerable infants.
Research highlights music therapy's effectiveness in treating traumatic brain injury and posttraumatic stress disorder among military personnel. Studies show that music can rebuild damaged neural connections, promote motivation, and improve patient outcomes.
Severe TBI in children increases risk for attention-deficit/hyperactivity disorder (ADHD) up to 7 years after injury. A study of 187 children with TBI compared to orthopedic injury found 25.7% developed secondary ADHD, highlighting the need for post-injury monitoring.
A new study found that severe combat wounds and chronic PTSD can increase the risk of developing high blood pressure. The research reviewed records of over 3,800 US service members who received intensive care for combat injuries sustained during the Iraq and Afghanistan wars.
Researchers at UCalgary have developed a portable brain imaging system that uses light to detect and monitor damage in the brain from concussion. The device measures communication in the brain by measuring oxygen levels, revealing patterns of blood flow and oxygen levels that change after concussion.
A recent review article emphasizes the urgent need for more clinical research, data, and prognostic models on traumatic brain injury in older adults. The lack of geriatric-specific TBI guidelines presents barriers to optimal care, and the authors discuss issues related to neurocritical care, neurosurgical management, and rehabilitation.
A new research from the University of Pennsylvania School of Medicine found that patients under 65 who are taken to a trauma center have a higher chance of being favorably discharged, while those over 65 have a lower risk of mortality. The study also highlights a serious care disparity for these severely injured patients.
A new study from UT Southwestern Medical Center found a correlation between traumatic brain injury and early-onset Alzheimer's disease. People who sustained concussions were diagnosed with dementia on average 2 1/2 years earlier than those without TBI.
Researchers recommend routine screening for Traumatic Brain Injury (TBI) in offenders to improve medical support and reduce crime. Young people with TBI are at greater risk of early, violent offending due to compromised neurological functions and increased risk of behavioral disorders.
The Kessler Foundation will conduct a pilot study assessing the clinical, functional and neurophysiological effectiveness of robotic exoskeleton-assisted gait therapy for children and young adults with traumatic brain injuries. The study aims to understand the neural mechanism involved in recovery through training.
A new Annals of Neurology study investigated the mechanisms and timing of events in the brain and circulation during the dying process. The findings suggest that spreading depolarization marks the loss of stored energy in brain cells, leading to death, but also highlight its reversibility with restored circulation.
A study by Georgetown University Medical Center found that babies who suffered a perinatal stroke regained language function in the opposite side of their brain. The research, led by Elissa L. Newport, PhD, discovered that teenagers and young adults used the right sides of their brains for language after a left-brain injury.
Researchers at Imperial College London found that xenon gas can limit blast-induced brain injury by preventing damage from developing. The study suggests that xenon could be a viable treatment option after blasts occur, potentially reducing debilitating symptoms.
Penn researchers have identified a neurological syndrome in US government personnel serving in Havana, Cuba, who reported hearing unusual noises and experiencing memory and thinking dysfunction, vision and balance problems. Rehabilitation interventions appear to improve symptoms.
A study published in PNAS suggests that video games can complement physical therapies to overcome attention deficit disorders, which contribute to motor skills disorders in stroke patients. The researchers analyzed brain injuries in 167 patients and found a connection between attention control areas and mobility problems.
A nationwide Swedish study found that traumatic brain injuries (TBI) significantly increase the risk of dementia diagnosis for over 30 years following the injury. The risk decreases over time but remains significant, with severe TBI or multiple TBIs increasing the risk even more.
A new study published in eNeuro found that a drug currently being evaluated for depression and suicidal tendencies also alleviates anxiety, fearful behaviors, and memory deficits in rats exposed to blast injuries. The drug, BCI-838, promotes the generation of new brain cells in the hippocampus.
The American Stroke Association honored 10 scientists and researchers for their significant contributions to stroke research, including Joanna Wardlaw, Walter Koroshetz, Jun Chen, and others. The award recognizes their work in investigating and managing clinical stroke science, basic stroke research, and more.
A Boston University study identified evidence of early Chronic Traumatic Encephalopathy (CTE) brain pathology after head impact, even in the absence of signs of concussion. The researchers found that head impact caused persistent changes in brain electrical functions and damaged blood vessels, leading to CTE.