A Boston University study identified evidence of early Chronic Traumatic Encephalopathy (CTE) brain pathology after head impact, even in the absence of signs of concussion. The researchers found that head impact caused persistent changes in brain electrical functions and damaged blood vessels, leading to CTE.
Dr. Chiaravalloti will test the modified Story Memory Technique's impact on new learning and memory abilities in older adults with mild cognitive impairment. The study aims to improve daily functioning and quality of life for this population.
A recent study published in ACS' Journal of Proteome Research reveals that signaling molecules play a crucial role in mild concussions. The research provides insights into the mechanisms underlying brain injury and recovery, potentially leading to the development of new treatments for traumatic brain injuries.
A preliminary study suggests that CranioSacral Therapy can improve range of motion, pain, sleep, and cognitive function in ex-NFL players with concussion and mild TBI. More clinical research data is needed to understand its effectiveness in treating post-concussive syndrome and potentially chronic traumatic encephalopathy.
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Researchers have found that brain implants can function with the help of glial cells, which are often overlooked as a potential target for treatment. The study suggests that glial cells play a critical role in maintaining optimal brain activity and suggest targeting them may improve current treatments for neurological diseases.
Researchers discovered that zebrafish exhibit significant spatial memory impairment after a blow to the head, with slower reaction times to familiar environments. Genetic analysis identified key genes involved in brain cell proliferation and migration, offering new insights into potential human recovery strategies.
A recent study reviewed 18 studies involving 7,587 patients, examining head injuries in MMA fighting published between 1990 and 2016. The review found no consistent definition or protocol for reporting and medical clearance return to play, making it impossible to determine the frequency and severity of these injuries.
A recent study in NeuroRehabilitation highlights the need for better addressing neurosexuality in patients with neurodisabilities, including members of the LGBTQIA+ community. The research provides guidance for healthcare providers and caregivers to improve sexual function and quality of life.
Researchers found that mild traumatic brain injury can lead to lifelong degenerative changes, including learning and working memory impairment. Studies on mice revealed ongoing neuroinflammation and neuron projection degeneration after a single or repetitive TBI, with some animals showing motor deficits.
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Researchers at the University of Geneva discovered the brain regions used to categorize emotions communicated vocally, highlighting the crucial role of the frontal lobe. The study found that the inferior frontal cortex is activated when categorizing and discriminating emotions from voices.
A Mayo Clinic study found that high school athletes are more likely to correctly identify a concussion as a brain injury than their parents and coaches. Athletes were also better at identifying typical symptoms of concussion but struggled with understanding how the injury occurs and criteria for returning to play.
Researchers at Moss Rehabilitation Research Institute are studying depression in people with traumatic brain injury (TBI) to understand the relationship between activity levels and mental health. The study aims to fine-tune depression treatment for TBI patients by exploring behavioral activation therapy.
A study published in the Journal of the American Academy of Orthopaedic Surgeons found that female athletes experience a higher concussion injury rate than male athletes. Athletes with a prior concussion injury were three times more likely to suffer another contact sport-related concussion.
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Researchers at MUSC develop an ex vivo model of ICP-induced cellular injury to understand early cell-injury mechanisms and identify biomarkers associated with pathological pressure. The novel model successfully initiates cellular stress in a cell-specific manner, offering potential for therapies to minimize neurological deficits.
A new Penn Medicine study found that female axons are smaller and have fewer microtubules, making them more susceptible to concussion. Women athletes are more likely to experience concussions and worse outcomes than men, possibly due to these anatomical differences.
New study reveals that five babies per 1,000 born in England may have sustained brain injury at or soon after birth, leading to serious conditions like cerebral palsy and blindness. The research, using routine NHS data, aims to better understand how to prevent brain injuries in preterm and full-term babies.
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The Northern New Jersey Traumatic Brain Injury System will improve quality of life for people with traumatic brain injury through comprehensive care, research, and resource dissemination. The system aims to optimize individual outcomes by addressing complex medical, cognitive, and psychosocial challenges.
A recent study published in JAMA Pediatrics found that microRNA levels in the saliva of children with mild traumatic brain injury can accurately identify those with prolonged concussion symptoms. This discovery holds promise for improving concussion management and reducing parental anxiety.
A study by McMaster University neuroscientists found that even mild trauma from contact sports can disrupt the production of new neurons in the hippocampus, a region critical to memory. Temporary memory losses were observed in concussed athletes, while scores improved after a reprieve from their sport.
Studies show that head impacts can cause lasting damage even without concussions, affecting brain connections and memory. Better helmet rules and concussion education are needed to ensure athlete safety.
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A study of firearms-related eye trauma in the US found significant racial disparities, with African Americans making up 35% of patients and suffering greater odds of being assaulted on the street. Whites were more likely to suffer self-inflicted injuries at home, while most common injury locations were the home and the street
Research explores military-related brain disorders and potential treatments, including improved visual responses and neural stem cell therapy. Disruptions in brain networks may underlie symptoms of Gulf War Illness, such as changes in vision, language function, pain perception, and mood regulation.
A new study has identified a promising treatment to reduce brain injury in newborns who have suffered from hypoxia-ischemia, a condition that can cause severe complications. The treatment involves combining standard cooling therapy with a selective Src kinase inhibitor to block a regulatory enzyme of apoptosis.
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MossRehab's Drucker Brain Injury Unit and MRRI have been recognized for excellence in TBI treatment and research. The facility has continuously funded research on outcome prediction and treatment since 1997.
A new study published in Journal of Neurotrauma found that traumatic spinal cord injuries can lead to persistent changes in metabolism, blood flow, and oxygenation up to 7 days post-injury. This suggests that current clinical practices may not be sufficient to prevent ischemia-related damage.
Cognivive's video games aim to enhance spatiotemporal cognitive abilities, building underlying capacity that different skills can draw on, improving real-world problem-solving abilities.
UNC researchers discovered that high-intensity shear shock waves amplify deep inside the brain, delivering a tenfold increase in tissue-ripping acceleration. This phenomenon may explain why some head knocks cause more harm than others.
A systematic review of 242,731 traumatic brain injuries in baseball and softball found poor helmet use and return-to-play guidelines. The study recommends mandatory helmet use, education, and economic incentives to reduce preventable injuries.
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A Lithuanian professor has been awarded the Paper of the Year by The Congress of Neurological Surgeons (CNS) for his groundbreaking research on severe traumatic brain injury. The study found that longer durations of cerebrovascular autoregulation impairment events significantly correlate with worse patient outcomes.
A new study finds that continuously recording aEEG data provides more accurate predictions of outcomes for infants undergoing cooling therapy. Infants with persistent abnormal patterns are at increased risk of adverse outcomes, highlighting the importance of continuous monitoring.
The study advocates for a holistic approach to understanding concussion, analyzing complex problems as whole systems and integrating research findings. Researchers hope this new method will lead to better diagnosis, evaluation, and treatment of TBI.
Scientists have discovered a key protein controlling ferroptosis, a highly regulated cell death process that plays a role in health and disease. The research links ferroptosis to diseases such as asthma, kidney injury, and brain trauma, suggesting potential drug targets for treatment.
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A recent study found that state-level TBI laws lead to a significant decline in the rate of recurrent concussions among US high school athletes approximately 2.5 years after implementation. The laws are reported to increase initial concussion reports and reduce recurrent concussions.
Researchers found that transcranial electrical stimulation significantly improved neural function in participants with mild traumatic brain injury, as shown by reduced abnormal slow-waves in MEG scans. The treatment also led to a significant reduction in post-concussion scores.
A recent evidence review found that collision sports, such as youth rugby, carry high rates of injury, including concussions. Experts argue that banning tackle and scrum in school rugby could significantly reduce these risks. In contrast, other strategies like wearing protective equipment have weak evidence supporting their effectiveness.
Researchers at Brigham Young University have developed a nano composite smartfoam that measures the impact of hits via electrical signals, collecting data in real time to determine impact severity and location. The technology has shown 90% accuracy in measuring concussion risks, revolutionizing football safety protocols.
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The University of Texas at San Antonio has assembled a world-class research enterprise to develop groundbreaking approaches for treating brain diseases and injuries. Researchers will collaborate on complex projects using expertise in neurodegenerative disease, regenerative medicine, and stem cell therapies.
Neutrophils, white blood cells that can cause damage after a hemorrhagic stroke, can be trained to release beneficial molecules like lactoferrin. This could lead to a new therapeutic approach for reducing brain damage after the injury.
Girls are significantly more likely than boys to return to play the same day after a soccer-related concussion, with over half of female athletes resuming play within 24 hours. This finding highlights the need for improved education and awareness among parents, coaches, and medical staff to prevent premature returns to play.
A study of 108 child patients found that 76% sustained at least one bone fracture, with skull fractures accounting for nearly half of all fractures. Children under 16 years old should not drive golf carts, and those using them should do so at cautious speeds.
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A Rutgers University study suggests that excessive neurogenesis after a traumatic head injury can lead to epileptic seizures and long-term cognitive decline. By preventing this process with a drug, the rate of brain cell birth returned to normal levels, reducing the risk of seizures.
Researchers used high-speed photography to study the formation of small bubbles in liquids, which can cause destructive shockwaves and potentially lead to brain trauma. The team developed an alternative formula to predict when cavitation will occur, with potential applications for athletic safety devices and military blast protection.
Worcester Polytechnic Institute Professor Songbai Ji is developing highly specific computer models of the head and brain to better diagnose concussions in real time. The models use neuroimaging data to assess injury risk and simulate real-time impact, providing athletic trainers with valuable tools to assess athlete safety.
A drug originally developed in the 1960s as an antiviral medication is showing promise in reducing aggression in traumatic brain injury patients. Amantadine, taken twice daily at 100mg, has been found to decrease aggression in multiple studies, improving quality of life for affected individuals.
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Researchers evaluate innovative treatments for common emotional problems after TBI, including videoconferencing technology and web-based interventions. Participants show significant improvements in emotional regulation, positive emotions, and problem-solving skills.
Researchers developed PupilScreen, a smartphone app that detects changes in pupil's response to light using AI-powered deep learning tools, promising improved diagnosis accuracy for concussion and TBI. The app can be used by coaches, parents, medics, and others on the sidelines of sports games or in emergency situations.
Researchers found overlap in activity of anterior cingulate cortex indicating pattern of self-regulation triggered by cognitive fatigue. The study broadens understanding of disease entities associated with lower threshold for cognitive fatigue.
A ground-breaking concussion study is underway, involving rugby players, to develop a rapid test for diagnosing concussions. The test, which measures biomarkers present in saliva and urine, has the potential to improve diagnosis and treatment of brain trauma, particularly in sports.
Researchers at UBC Okanagan campus have developed a new technique using ultrasound equipment to measure brain blood flow, providing a potential tool for diagnosing concussions. The study found a clear link between the brain injury and changes in blood flow response.
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A recent study of over 5 years of pediatric patients treated for sports concussion found that magnetic resonance imaging (MRI) revealed structural changes to the brain related to persistent symptoms. However, the study indicated that MRI in children with persistent symptoms after concussion rarely identified brain injury.
A retrospective study of nearly 1,100 patients with severe TBI found that ICP monitoring was associated with a significant decrease in mortality rates, but no improvement in favorable outcomes. The study also showed that ICP monitoring was linked to more aggressive therapy.
Research suggests that traumatic brain injuries in childhood and adolescence can increase the risk of alcohol abuse problems in adulthood. The study found a clearer link between brain injury and alcohol abuse in people who suffered an injury before age 5, with children under 5 being over 3.6 times more likely to exhibit substance abuse...
The University of Michigan Injury Center has received $2.5 million from the CDC to continue its research on preventing injuries such as opioid overdoses, concussion, and motor vehicle crashes. The center aims to reduce injury by publishing innovative research and translating it into practice for local communities.
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Children who develop brain injury due to non-fatal drowning often suffer from severe motor deficits, while maintaining relatively intact perceptual and cognitive abilities. The study used resting-state functional magnetic resonance imaging to assess brain integrity in 11 children with quadriplegia caused by drowning-induced brain injury.
Researchers found that trigeminal nerve stimulation increased cerebral blood flow and oxygen delivery to the brain in animal models with traumatic brain injury, reducing secondary injury. This study provides strong evidence for the potential of TNS as a novel therapeutic strategy for managing TBI.
Researchers analyzed concussion data from national high school surveillance system, finding a decrease in severe symptoms like amnesia and an increase in dizziness and light sensitivity. Clinicians may be over-diagnosing concussions, while diagnostic tools have shifted to more computerized and non-invasive methods.
Researchers found that memantine significantly reduced blood levels of neuron-specific enolase, a marker of neuronal damage, in patients with moderate TBI. The study also showed marked improvements in Glasgow Coma Scale scores on day 3, indicating potential therapeutic benefits.
A new research group at the University of Cambridge aims to improve care for patients with traumatic brain injury (TBI) in low- and middle-income countries. The group will focus on preventing, investigating, treating, and improving outcomes for head-injured patients in these regions.
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A UTA professor's study found that many parents have a limited understanding of concussions and their impact on children's futures. The research highlights the importance of educating caregivers to recognize symptoms and protect youth athletes.
Researchers found elevated levels of two brain injury markers, neurofilament light chain and tau, in active professional fighters compared to retired fighters or non-fighters. These markers may signify permanent traumatic brain injury with long-term consequences.